Click here to switch to the map view.

The map label for this gene is ompR [H]

Identifier: 77460594

GI number: 77460594

Start: 4927468

End: 4928199

Strand: Reverse

Name: ompR [H]

Synonym: Pfl01_4373

Alternate gene names: 77460594

Gene position: 4928199-4927468 (Counterclockwise)

Preceding gene: 77460595

Following gene: 77460593

Centisome position: 76.54

GC content: 63.66

Gene sequence:

>732_bases
GTGAGCTCAGTCAACAAGTCGATTTTGTTGGTCGATGACGACCAGGAGATACGCGAGTTGCTGGAAACCTACCTGACCCG
CGCGGGTTTTCAGGTACGGGCCACGGCGGATGGCGCCGGTTTTCGTCAGGCGCTGAACGAGGCGCCGAGCGATCTGGTGA
TCCTCGATGTGATGCTGCCCGATGAAGACGGCTTCAGCCTGTGCCGTTGGGTGCGCCAGCATCCGCGTCAGGCTCAGGTG
CCGATCATCATGCTCACCGCCAGTTCCGACGAAGCCGACCGGGTCATCGGCCTGGAGCTCGGCGCCGACGATTACCTCGG
CAAACCTTTCAGCCCCCGCGAACTGCAGGCCCGGATCAAGGCCCTGCTGCGCCGCGCCCAATTCGGCCAGGAACGCGGCG
GCAGTGAAGTGCTGGCGTTCGATGAATGGCGGCTGGACATGGTCAGCCATCGGCTGTTTCACGCCGACGGCGAGGAGGTG
ATTCTGTCCGGCGCCGACTTCGCCCTGTTGAAACTGTTTCTTGATCATCCCCAGGAAATCCTCGACCGCGACACCATCGG
CAACGCCACCCGTGGCCGCGACCTGATGCCCCTCGACCGCATCGTCGACATGGCCGTCAGCCGTTTGCGCCAGCGTCTGC
GCGACACCGAAAAACCGCCGCGCCTGATCCGCACCGTGCGTGGCAGCGGCTACCAACTGGCAGCCAATGTGGTTGCCGGC
AATGGTCACTGA

Upstream 100 bases:

>100_bases
CTCGAACAATCCGGTCAATGATCATTCCCACGCCGGGCGTGGGAACCCTCGACACATCAGGCATAATCCGCCCAATTCCA
ACAACAAGGATGCCTTCGAA

Downstream 100 bases:

>100_bases
GTTCCTGCGCACCACCGCGCGCAAAGTGCCGATGCCGCGTTCGCTGCTCGGGCGGATGCTGCTGCTGACGTTGCTCGCGG
TGTTGTTCGCCCAGACGCTG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MSSVNKSILLVDDDQEIRELLETYLTRAGFQVRATADGAGFRQALNEAPSDLVILDVMLPDEDGFSLCRWVRQHPRQAQV
PIIMLTASSDEADRVIGLELGADDYLGKPFSPRELQARIKALLRRAQFGQERGGSEVLAFDEWRLDMVSHRLFHADGEEV
ILSGADFALLKLFLDHPQEILDRDTIGNATRGRDLMPLDRIVDMAVSRLRQRLRDTEKPPRLIRTVRGSGYQLAANVVAG
NGH

Sequences:

>Translated_243_residues
MSSVNKSILLVDDDQEIRELLETYLTRAGFQVRATADGAGFRQALNEAPSDLVILDVMLPDEDGFSLCRWVRQHPRQAQV
PIIMLTASSDEADRVIGLELGADDYLGKPFSPRELQARIKALLRRAQFGQERGGSEVLAFDEWRLDMVSHRLFHADGEEV
ILSGADFALLKLFLDHPQEILDRDTIGNATRGRDLMPLDRIVDMAVSRLRQRLRDTEKPPRLIRTVRGSGYQLAANVVAG
NGH
>Mature_242_residues
SSVNKSILLVDDDQEIRELLETYLTRAGFQVRATADGAGFRQALNEAPSDLVILDVMLPDEDGFSLCRWVRQHPRQAQVP
IIMLTASSDEADRVIGLELGADDYLGKPFSPRELQARIKALLRRAQFGQERGGSEVLAFDEWRLDMVSHRLFHADGEEVI
LSGADFALLKLFLDHPQEILDRDTIGNATRGRDLMPLDRIVDMAVSRLRQRLRDTEKPPRLIRTVRGSGYQLAANVVAGN
GH

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=44.3478260869565, Blast_Score=191, Evalue=4e-50,
Organism=Escherichia coli, GI1790863, Length=234, Percent_Identity=36.3247863247863, Blast_Score=157, Evalue=6e-40,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=37.8260869565217, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI2367329, Length=236, Percent_Identity=40.2542372881356, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1787229, Length=235, Percent_Identity=37.4468085106383, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1788394, Length=236, Percent_Identity=35.1694915254237, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1786784, Length=233, Percent_Identity=37.7682403433476, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI87082012, Length=229, Percent_Identity=37.5545851528384, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1790860, Length=229, Percent_Identity=35.8078602620087, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI145693140, Length=241, Percent_Identity=32.3651452282158, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1786911, Length=228, Percent_Identity=34.6491228070175, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1790552, Length=230, Percent_Identity=33.9130434782609, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1789402, Length=228, Percent_Identity=37.719298245614, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=30.8035714285714, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI1788550, Length=131, Percent_Identity=29.0076335877863, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790299, Length=124, Percent_Identity=33.8709677419355, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787487, Length=141, Percent_Identity=31.2056737588652, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27242; Mature: 27111

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSVNKSILLVDDDQEIRELLETYLTRAGFQVRATADGAGFRQALNEAPSDLVILDVMLP
CCCCCCCEEEEECCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHCCCCCEEEEEEEEC
DEDGFSLCRWVRQHPRQAQVPIIMLTASSDEADRVIGLELGADDYLGKPFSPRELQARIK
CCCCHHHHHHHHHCCCCCCCCEEEEECCCCCCCCEEEEEECCCHHCCCCCCHHHHHHHHH
ALLRRAQFGQERGGSEVLAFDEWRLDMVSHRLFHADGEEVILSGADFALLKLFLDHPQEI
HHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCHHHH
LDRDTIGNATRGRDLMPLDRIVDMAVSRLRQRLRDTEKPPRLIRTVRGSGYQLAANVVAG
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEEEEECC
NGH
CCC
>Mature Secondary Structure 
SSVNKSILLVDDDQEIRELLETYLTRAGFQVRATADGAGFRQALNEAPSDLVILDVMLP
CCCCCCEEEEECCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHCCCCCEEEEEEEEC
DEDGFSLCRWVRQHPRQAQVPIIMLTASSDEADRVIGLELGADDYLGKPFSPRELQARIK
CCCCHHHHHHHHHCCCCCCCCEEEEECCCCCCCCEEEEEECCCHHCCCCCCHHHHHHHHH
ALLRRAQFGQERGGSEVLAFDEWRLDMVSHRLFHADGEEVILSGADFALLKLFLDHPQEI
HHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCHHHH
LDRDTIGNATRGRDLMPLDRIVDMAVSRLRQRLRDTEKPPRLIRTVRGSGYQLAANVVAG
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEEEEECC
NGH
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]