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The map label for this gene is bdlA [H]

Identifier: 77460529

GI number: 77460529

Start: 4865350

End: 4866669

Strand: Direct

Name: bdlA [H]

Synonym: Pfl01_4308

Alternate gene names: 77460529

Gene position: 4865350-4866669 (Clockwise)

Preceding gene: 77460528

Following gene: 77460530

Centisome position: 75.57

GC content: 58.86

Gene sequence:

>1320_bases
ATGATTTTCAATCGTCACAAGACCGTCCTCGTCGATCTTCAAAACACCATCAACCAACAAGCCGGCCTGTTGGAAGCGAT
CAACCGCTCCATGGCAGTGATCGAATTCGATGTCGACGGTATCGTTCTGCGCGCCAACGACAACTTCCTGAAAACCATGG
GTTACACCCGCGAACAGGTAGTCGGGCAACCCCATCGTCATTTCTGTTCTCCAGAGTTTGCCCGTGGCAATCAGTACACC
GAGTTGTGGTCGCGATTGAAAAGCGGCCAGTTCCAGTCCGGCACCTTTGAACGCATCGACAGTCAGGGCCGACCGATCTG
GCTCGAAGCCAGCTATAACCCGATCAAGGATGACTCGGGCCGCGTGGTGAAAGTGGTCAAGTACGCCATGGATGTCACCG
CCAAAGTGCAGCAGGAAAGCGAAGCCAATGCGAAATTGCAGGCGATCGACCGCGCCATGGCGGTGATCGAATTCGATCTC
GACGGCAATATTCTCACCGCCAATCAGAATTTCCTGACGCGCATGGGTTACACCCTTGCCGAACTCAAAGGCAAACATCA
CCGCTTGTTCTGCCCCGCGCAACTGGTCAACAGCAGCGCCTACCAGGATTTCTGGCGCCGGTTGAATCAGGGCGAACTGT
TTCAGGGCCAGTTCGAACGCGTCGACAAACGTGGTCAGACCGTATGGCTGGAAGCCAATTACAACCCGGTCTACGACGCC
GCCGGCCGCTTGTGCAAAGTGGTGAAGTTCGCGTCGGACGTGACCGCCCGGGTCGAACAGCACGAGCAGGATGCGCGCAG
TGCCAGCGCGGCCTATCACATCTCGGTGGCCACCCGAAAAGTCGCCGAGCAAGGTACGCAAGTGATTCAGCAAGCCGCCA
GTGAAATGCGCGAGATTGCCGACGACATTGCCGAATCCTCAACCCTCATCGCGCAGCTCGGCGAACGCTCCGAGCAGATC
ACTGCCATCGTCAACACCATCCGCGCGATTGCCGATCAGACCAATCTTTTGGCCCTGAACGCTGCAATCGAAGCCGCCCG
AGCCGGTGAGCAGGGTCGCGGTTTTGCCGTGGTGGCCGATGAAGTGCGGCAGCTGGCAGCGCGCACCAGCGGCTCCACTG
CGGAAATTTCCAACATGATCAGCCTGATCCAGACCGAAACCCGTCAGGCGATCAAGAGCATGGACGGCACCCGAGGGCGT
GCGGCGCAAGGTGTGGAGCTGGCGGATCAGGCCGGTACGGTGATTCTGCAGATTCGGGACGGCGCCAGCGAGGCGGTGGA
AGCGGTGAGCATGTTTGCCAACGAGCGTGCGCCGGGATAA

Upstream 100 bases:

>100_bases
CCAGGATGCTGGCACACTGCTTCCAGCCATCGAGATATCTGGCTGGCTGACGCGGAAACAGGGACCCCACCTTCAGCCCT
ATTTCCAGAGTGCCACGAGC

Downstream 100 bases:

>100_bases
GGCCAACACGGGCGACGCAGGGCTATAGTGACTCAACGTCCCAAGCCCTGCCGAGTCCGTCATGACCACCGAAAAAACCG
AATCATCCACCGCCCCTGTC

Product: Pas/Pac sensor-containing chemotaxis sensory transducer

Products: NA

Alternate protein names: Chemotaxis regulator BdlA [H]

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MIFNRHKTVLVDLQNTINQQAGLLEAINRSMAVIEFDVDGIVLRANDNFLKTMGYTREQVVGQPHRHFCSPEFARGNQYT
ELWSRLKSGQFQSGTFERIDSQGRPIWLEASYNPIKDDSGRVVKVVKYAMDVTAKVQQESEANAKLQAIDRAMAVIEFDL
DGNILTANQNFLTRMGYTLAELKGKHHRLFCPAQLVNSSAYQDFWRRLNQGELFQGQFERVDKRGQTVWLEANYNPVYDA
AGRLCKVVKFASDVTARVEQHEQDARSASAAYHISVATRKVAEQGTQVIQQAASEMREIADDIAESSTLIAQLGERSEQI
TAIVNTIRAIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRQLAARTSGSTAEISNMISLIQTETRQAIKSMDGTRGR
AAQGVELADQAGTVILQIRDGASEAVEAVSMFANERAPG

Sequences:

>Translated_439_residues
MIFNRHKTVLVDLQNTINQQAGLLEAINRSMAVIEFDVDGIVLRANDNFLKTMGYTREQVVGQPHRHFCSPEFARGNQYT
ELWSRLKSGQFQSGTFERIDSQGRPIWLEASYNPIKDDSGRVVKVVKYAMDVTAKVQQESEANAKLQAIDRAMAVIEFDL
DGNILTANQNFLTRMGYTLAELKGKHHRLFCPAQLVNSSAYQDFWRRLNQGELFQGQFERVDKRGQTVWLEANYNPVYDA
AGRLCKVVKFASDVTARVEQHEQDARSASAAYHISVATRKVAEQGTQVIQQAASEMREIADDIAESSTLIAQLGERSEQI
TAIVNTIRAIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRQLAARTSGSTAEISNMISLIQTETRQAIKSMDGTRGR
AAQGVELADQAGTVILQIRDGASEAVEAVSMFANERAPG
>Mature_439_residues
MIFNRHKTVLVDLQNTINQQAGLLEAINRSMAVIEFDVDGIVLRANDNFLKTMGYTREQVVGQPHRHFCSPEFARGNQYT
ELWSRLKSGQFQSGTFERIDSQGRPIWLEASYNPIKDDSGRVVKVVKYAMDVTAKVQQESEANAKLQAIDRAMAVIEFDL
DGNILTANQNFLTRMGYTLAELKGKHHRLFCPAQLVNSSAYQDFWRRLNQGELFQGQFERVDKRGQTVWLEANYNPVYDA
AGRLCKVVKFASDVTARVEQHEQDARSASAAYHISVATRKVAEQGTQVIQQAASEMREIADDIAESSTLIAQLGERSEQI
TAIVNTIRAIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRQLAARTSGSTAEISNMISLIQTETRQAIKSMDGTRGR
AAQGVELADQAGTVILQIRDGASEAVEAVSMFANERAPG

Specific function: Essential for biofilm dispersion by sensing environmental cues. May be involved in sensing and transducing signals within cells, resulting in the modulation of c-di-GMP levels, swimming motility and adhesiveness of the bacterial cell surface [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=127, Percent_Identity=43.3070866141732, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1788195, Length=127, Percent_Identity=44.0944881889764, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1789453, Length=175, Percent_Identity=37.1428571428571, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1788194, Length=143, Percent_Identity=38.4615384615385, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1787690, Length=137, Percent_Identity=39.4160583941606, Blast_Score=79, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00015 MCPsignal; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: NA

Molecular weight: Translated: 48516; Mature: 48516

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFNRHKTVLVDLQNTINQQAGLLEAINRSMAVIEFDVDGIVLRANDNFLKTMGYTREQV
CCCCCCCEEEEEEHHHHHHHHHHHHHHCCCEEEEEEECCEEEEEECCCHHHHCCCCHHHH
VGQPHRHFCSPEFARGNQYTELWSRLKSGQFQSGTFERIDSQGRPIWLEASYNPIKDDSG
CCCCHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHCCCCCEEEEECCCCCCCCCCC
RVVKVVKYAMDVTAKVQQESEANAKLQAIDRAMAVIEFDLDGNILTANQNFLTRMGYTLA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEECCCHHHHHHCHHHH
ELKGKHHRLFCPAQLVNSSAYQDFWRRLNQGELFQGQFERVDKRGQTVWLEANYNPVYDA
HHCCCCCEEECHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEEECCCCCHHHH
AGRLCKVVKFASDVTARVEQHEQDARSASAAYHISVATRKVAEQGTQVIQQAASEMREIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
DDIAESSTLIAQLGERSEQITAIVNTIRAIADQTNLLALNAAIEAARAGEQGRGFAVVAD
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCEEEEHH
EVRQLAARTSGSTAEISNMISLIQTETRQAIKSMDGTRGRAAQGVELADQAGTVILQIRD
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCEEEEEECC
GASEAVEAVSMFANERAPG
CHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIFNRHKTVLVDLQNTINQQAGLLEAINRSMAVIEFDVDGIVLRANDNFLKTMGYTREQV
CCCCCCCEEEEEEHHHHHHHHHHHHHHCCCEEEEEEECCEEEEEECCCHHHHCCCCHHHH
VGQPHRHFCSPEFARGNQYTELWSRLKSGQFQSGTFERIDSQGRPIWLEASYNPIKDDSG
CCCCHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHCCCCCEEEEECCCCCCCCCCC
RVVKVVKYAMDVTAKVQQESEANAKLQAIDRAMAVIEFDLDGNILTANQNFLTRMGYTLA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEECCCHHHHHHCHHHH
ELKGKHHRLFCPAQLVNSSAYQDFWRRLNQGELFQGQFERVDKRGQTVWLEANYNPVYDA
HHCCCCCEEECHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEEECCCCCHHHH
AGRLCKVVKFASDVTARVEQHEQDARSASAAYHISVATRKVAEQGTQVIQQAASEMREIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
DDIAESSTLIAQLGERSEQITAIVNTIRAIADQTNLLALNAAIEAARAGEQGRGFAVVAD
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCEEEEHH
EVRQLAARTSGSTAEISNMISLIQTETRQAIKSMDGTRGRAAQGVELADQAGTVILQIRD
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCEEEEEECC
GASEAVEAVSMFANERAPG
CHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]