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The map label for this gene is adrA [H]

Identifier: 77460528

GI number: 77460528

Start: 4864122

End: 4865174

Strand: Direct

Name: adrA [H]

Synonym: Pfl01_4307

Alternate gene names: 77460528

Gene position: 4864122-4865174 (Clockwise)

Preceding gene: 77460527

Following gene: 77460529

Centisome position: 75.55

GC content: 59.26

Gene sequence:

>1053_bases
ATGGAAAACCAACGCGGCAAAGGTTTGTCATTCGCCAGGCGCATTTACTTGCCACGGTCCATCGGATTGGGCATCGGCTT
CTTCAGTGTCGGTGCCGCGCTGTATCCGTTGAACATGCCGGGCTGGCTCTGGGCGCTGTTGCTGTTCAACGGTTTTCTCT
GGCCGCATGTGGCCTATCAATGCTCGACCCGCTCGGCTTTCCCCTATCGCGCTGAACGCCGCAACCTGCTCTATGACTCG
GTGTGCGGCGGTTTCTGGACCGCGTGTTTCCAGTTCAACCCGCTGACCACCGTGACCATTCTGTCGATGATGACCATGAA
CAACGTGGCCGCCGGTGGCGTGCGCCTGTTCTGGCTGGGCGCCCTCGCCCAGTTGATCGGCGTGCTGCTGGGCTGGTCAG
TGTTCGGCGTCCATTTCACCCTGACGGCCACGCAGACTCAGGTCTGGGCCTGCCTGCCGATGCTGACCCTTTATCCGCTG
GCTTTGGGAATGGTTTGCTACCGGTTGGCGATCAAACTCGCCGAACATAAACGCACCCTGAGCGCCCTGAGCCGTACTGA
CAGCCTGACGGGACTGCTCAACCACGGCGCCTGGAAAGACCTGCTGCACCTCAAGTTCCAACAGTGCCGCCAGCACAATT
CCCAAGCCATTCTGGCGCTGATCGACATCGATCATTTCAAGTCGATCAACGACAGTTACGGGCACATCGTCGGCGACGCG
GTGCTGCGGCAGTTAAGCCATGAGCTGAAATTCGTACTCGACGAAAGCAAGCTGGCCGGGCGTTACGGTGGCGATGAATT
CTGTGTGATCCTGCCCAACCTGCCCCTGAGCAAGGCTGAAGCGCTGATGGAGCAACTGCGTCAGGCACTGGATCGATACC
GCCATCCCGACGTTTCCGAGCTGCGGGTCAGCCTGAGTATCGGGCTTGCTCGCTATCAAACCTCTTACGCCGATGCCCTT
GAGTGGTTCGAAGATTCCGACAAGGCGTTGTACACGGCCAAGCACACGGGACGTAACACAATCAGCGTAGCGTTGACCCG
ATCACCCGCCTGA

Upstream 100 bases:

>100_bases
CCCGCTGGAATAAATGACAATGTCTGTCATTGGCCGATGAACGGTCTGTCTGAAGAATTACACTGCAAAGTGTTTCAGAA
TGAATCTGGCGTAGAACATC

Downstream 100 bases:

>100_bases
AAAAACTTGTACAAAATTGAGAAAAATCGATTTCTTGTACAAGTTTATAAAGTTTTGTATAAGTTAATCCGCCAGCCAGG
ATGCTGGCACACTGCTTCCA

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MENQRGKGLSFARRIYLPRSIGLGIGFFSVGAALYPLNMPGWLWALLLFNGFLWPHVAYQCSTRSAFPYRAERRNLLYDS
VCGGFWTACFQFNPLTTVTILSMMTMNNVAAGGVRLFWLGALAQLIGVLLGWSVFGVHFTLTATQTQVWACLPMLTLYPL
ALGMVCYRLAIKLAEHKRTLSALSRTDSLTGLLNHGAWKDLLHLKFQQCRQHNSQAILALIDIDHFKSINDSYGHIVGDA
VLRQLSHELKFVLDESKLAGRYGGDEFCVILPNLPLSKAEALMEQLRQALDRYRHPDVSELRVSLSIGLARYQTSYADAL
EWFEDSDKALYTAKHTGRNTISVALTRSPA

Sequences:

>Translated_350_residues
MENQRGKGLSFARRIYLPRSIGLGIGFFSVGAALYPLNMPGWLWALLLFNGFLWPHVAYQCSTRSAFPYRAERRNLLYDS
VCGGFWTACFQFNPLTTVTILSMMTMNNVAAGGVRLFWLGALAQLIGVLLGWSVFGVHFTLTATQTQVWACLPMLTLYPL
ALGMVCYRLAIKLAEHKRTLSALSRTDSLTGLLNHGAWKDLLHLKFQQCRQHNSQAILALIDIDHFKSINDSYGHIVGDA
VLRQLSHELKFVLDESKLAGRYGGDEFCVILPNLPLSKAEALMEQLRQALDRYRHPDVSELRVSLSIGLARYQTSYADAL
EWFEDSDKALYTAKHTGRNTISVALTRSPA
>Mature_350_residues
MENQRGKGLSFARRIYLPRSIGLGIGFFSVGAALYPLNMPGWLWALLLFNGFLWPHVAYQCSTRSAFPYRAERRNLLYDS
VCGGFWTACFQFNPLTTVTILSMMTMNNVAAGGVRLFWLGALAQLIGVLLGWSVFGVHFTLTATQTQVWACLPMLTLYPL
ALGMVCYRLAIKLAEHKRTLSALSRTDSLTGLLNHGAWKDLLHLKFQQCRQHNSQAILALIDIDHFKSINDSYGHIVGDA
VLRQLSHELKFVLDESKLAGRYGGDEFCVILPNLPLSKAEALMEQLRQALDRYRHPDVSELRVSLSIGLARYQTSYADAL
EWFEDSDKALYTAKHTGRNTISVALTRSPA

Specific function: Unknown

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=343, Percent_Identity=38.7755102040816, Blast_Score=267, Evalue=6e-73,
Organism=Escherichia coli, GI1787262, Length=169, Percent_Identity=31.3609467455621, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1787541, Length=177, Percent_Identity=33.8983050847458, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI87082007, Length=158, Percent_Identity=34.1772151898734, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1788381, Length=214, Percent_Identity=29.9065420560748, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI87081881, Length=188, Percent_Identity=36.1702127659575, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87081977, Length=177, Percent_Identity=34.4632768361582, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI145693134, Length=159, Percent_Identity=30.188679245283, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787802, Length=144, Percent_Identity=31.25, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87081974, Length=165, Percent_Identity=31.5151515151515, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787056, Length=128, Percent_Identity=35.9375, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1787816, Length=163, Percent_Identity=30.0613496932515, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788956, Length=154, Percent_Identity=31.8181818181818, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR007894 [H]

Pfam domain/function: PF00990 GGDEF; PF05230 MASE2 [H]

EC number: NA

Molecular weight: Translated: 39236; Mature: 39236

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENQRGKGLSFARRIYLPRSIGLGIGFFSVGAALYPLNMPGWLWALLLFNGFLWPHVAYQ
CCCCCCCCHHHHHHHHCCHHHCCCCHHHHHHHEEECCCCHHHHHHHHHHCCCHHHHHHHE
CSTRSAFPYRAERRNLLYDSVCGGFWTACFQFNPLTTVTILSMMTMNNVAAGGVRLFWLG
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
ALAQLIGVLLGWSVFGVHFTLTATQTQVWACLPMLTLYPLALGMVCYRLAIKLAEHKRTL
HHHHHHHHHHHHHHHHEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SALSRTDSLTGLLNHGAWKDLLHLKFQQCRQHNSQAILALIDIDHFKSINDSYGHIVGDA
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHCCCCCHHHHHHHH
VLRQLSHELKFVLDESKLAGRYGGDEFCVILPNLPLSKAEALMEQLRQALDRYRHPDVSE
HHHHHHHHHHHHHCHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHH
LRVSLSIGLARYQTSYADALEWFEDSDKALYTAKHTGRNTISVALTRSPA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEECCCC
>Mature Secondary Structure
MENQRGKGLSFARRIYLPRSIGLGIGFFSVGAALYPLNMPGWLWALLLFNGFLWPHVAYQ
CCCCCCCCHHHHHHHHCCHHHCCCCHHHHHHHEEECCCCHHHHHHHHHHCCCHHHHHHHE
CSTRSAFPYRAERRNLLYDSVCGGFWTACFQFNPLTTVTILSMMTMNNVAAGGVRLFWLG
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
ALAQLIGVLLGWSVFGVHFTLTATQTQVWACLPMLTLYPLALGMVCYRLAIKLAEHKRTL
HHHHHHHHHHHHHHHHEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SALSRTDSLTGLLNHGAWKDLLHLKFQQCRQHNSQAILALIDIDHFKSINDSYGHIVGDA
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHCCCCCHHHHHHHH
VLRQLSHELKFVLDESKLAGRYGGDEFCVILPNLPLSKAEALMEQLRQALDRYRHPDVSE
HHHHHHHHHHHHHCHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHH
LRVSLSIGLARYQTSYADALEWFEDSDKALYTAKHTGRNTISVALTRSPA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]