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The map label for this gene is ycgR [H]

Identifier: 77460478

GI number: 77460478

Start: 4802773

End: 4803507

Strand: Direct

Name: ycgR [H]

Synonym: Pfl01_4257

Alternate gene names: 77460478

Gene position: 4802773-4803507 (Clockwise)

Preceding gene: 77460477

Following gene: 77460483

Centisome position: 74.6

GC content: 59.05

Gene sequence:

>735_bases
GTGTCCAATGATGACGCTCCGCAGCCCCCAAAGGTGCTTACCACGCCCCTGGAGATCTCCAGCAATCTGCGCCAGCTGCT
TGAAAGCCATGATCCGCTGATCATCACCTTCCACGAGCGCAGCCAGCGCTTCCAGAGCTATCTGATCAAGGTTGACCGGG
AAACCGCCACGATTGCCCTGGACGAGATGATCCCGCGCGATGGCGAACGCTTCCTGCTCGCCGGCGAGCCGTTCAAGGTC
GAAGGTTTTCATGACGGTGTGCGCATTGCCTGGGAATGCAACGGCACGCTGAACATCGAAGAATCCAGTGGCGACCGCTT
CTACACCGGCGACCTGCCCACCGAAGTGGTTTATCACCAGCGCCGCAACGCCTTCCGCGCAGCCCTCAAGCTGACCGATC
TGGTCAGCGTTGTGCTCGGTGGCGAAAAGCTCAAGGCACCGATCGACGGCAAACTGCTGGATATCTCCGCCACTGGCTGC
AAACTGCGTTTCGAAGGCGACATCACCGACCGTCTGCAATTGGGCCAGGTTTATGATCGTCTGATCGCCGCGCCGTTGTT
CGGCAACCAGCCGACCTCGGTCGAGTTGCGTTACCTGCACTTCGAAGAAAAACTCAACATCACTTTCGCCGGCCTGCGTT
TTCACAACATCAGCGGCCCGGCGGCCCGCAACGTCGAGCGTTTCGTTTATCAACTGCAACGCGAAGCGCGTCGGTTCGAT
AAAGACGACCTCTGA

Upstream 100 bases:

>100_bases
CGTGATGCTTTCTTCCATGCTTGCGCCCTATCAACGTGCGAAACATGCTGGCAAAATACTGGCCAGCCGTAGTCAAATTT
TGTCTGGAGATTGATTTAAC

Downstream 100 bases:

>100_bases
TCGGCAAGCATAAAAAACGGGCAGTCACTGCGGTGACTGCCCGTTTTTTTATGCCTGAATCACGGTCTGGCGGGGCTGAT
GTCCGGCCCTTCGCCTTCGA

Product: hypothetical protein

Products: NA

Alternate protein names: Cyclic di-GMP binding protein YcgR [H]

Number of amino acids: Translated: 244; Mature: 243

Protein sequence:

>244_residues
MSNDDAPQPPKVLTTPLEISSNLRQLLESHDPLIITFHERSQRFQSYLIKVDRETATIALDEMIPRDGERFLLAGEPFKV
EGFHDGVRIAWECNGTLNIEESSGDRFYTGDLPTEVVYHQRRNAFRAALKLTDLVSVVLGGEKLKAPIDGKLLDISATGC
KLRFEGDITDRLQLGQVYDRLIAAPLFGNQPTSVELRYLHFEEKLNITFAGLRFHNISGPAARNVERFVYQLQREARRFD
KDDL

Sequences:

>Translated_244_residues
MSNDDAPQPPKVLTTPLEISSNLRQLLESHDPLIITFHERSQRFQSYLIKVDRETATIALDEMIPRDGERFLLAGEPFKV
EGFHDGVRIAWECNGTLNIEESSGDRFYTGDLPTEVVYHQRRNAFRAALKLTDLVSVVLGGEKLKAPIDGKLLDISATGC
KLRFEGDITDRLQLGQVYDRLIAAPLFGNQPTSVELRYLHFEEKLNITFAGLRFHNISGPAARNVERFVYQLQREARRFD
KDDL
>Mature_243_residues
SNDDAPQPPKVLTTPLEISSNLRQLLESHDPLIITFHERSQRFQSYLIKVDRETATIALDEMIPRDGERFLLAGEPFKVE
GFHDGVRIAWECNGTLNIEESSGDRFYTGDLPTEVVYHQRRNAFRAALKLTDLVSVVLGGEKLKAPIDGKLLDISATGCK
LRFEGDITDRLQLGQVYDRLIAAPLFGNQPTSVELRYLHFEEKLNITFAGLRFHNISGPAARNVERFVYQLQREARRFDK
DDL

Specific function: Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility. Binds c-di-GMP with a dissociation constant of 165 nM [H]

COG id: COG5581

COG function: function code M; Predicted glycosyltransferase

Gene ontology:

Cell location: Bacterial flagellum basal body [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PilZ domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009875
- InterPro:   IPR012349
- InterPro:   IPR009926 [H]

Pfam domain/function: PF07238 PilZ; PF07317 YcgR [H]

EC number: NA

Molecular weight: Translated: 27773; Mature: 27642

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNDDAPQPPKVLTTPLEISSNLRQLLESHDPLIITFHERSQRFQSYLIKVDRETATIAL
CCCCCCCCCCCEEECHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHEEECCCCEEEEE
DEMIPRDGERFLLAGEPFKVEGFHDGVRIAWECNGTLNIEESSGDRFYTGDLPTEVVYHQ
HHHCCCCCCEEEEECCCEEECCCCCCEEEEEEECCEEEEECCCCCEEEECCCCHHHHHHH
RRNAFRAALKLTDLVSVVLGGEKLKAPIDGKLLDISATGCKLRFEGDITDRLQLGQVYDR
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCEEEEECCCCHHHHHHHHHHHH
LIAAPLFGNQPTSVELRYLHFEEKLNITFAGLRFHNISGPAARNVERFVYQLQREARRFD
HHHCCCCCCCCCCEEEEEEEEECCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCC
KDDL
CCCC
>Mature Secondary Structure 
SNDDAPQPPKVLTTPLEISSNLRQLLESHDPLIITFHERSQRFQSYLIKVDRETATIAL
CCCCCCCCCCEEECHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHEEECCCCEEEEE
DEMIPRDGERFLLAGEPFKVEGFHDGVRIAWECNGTLNIEESSGDRFYTGDLPTEVVYHQ
HHHCCCCCCEEEEECCCEEECCCCCCEEEEEEECCEEEEECCCCCEEEECCCCHHHHHHH
RRNAFRAALKLTDLVSVVLGGEKLKAPIDGKLLDISATGCKLRFEGDITDRLQLGQVYDR
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCEEEEECCCCHHHHHHHHHHHH
LIAAPLFGNQPTSVELRYLHFEEKLNITFAGLRFHNISGPAARNVERFVYQLQREARRFD
HHHCCCCCCCCCCEEEEEEEEECCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCC
KDDL
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12534463 [H]