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The map label for this gene is ydiD [C]

Identifier: 77460426

GI number: 77460426

Start: 4745710

End: 4747365

Strand: Reverse

Name: ydiD [C]

Synonym: Pfl01_4205

Alternate gene names: 77460426

Gene position: 4747365-4745710 (Counterclockwise)

Preceding gene: 77460427

Following gene: 77460425

Centisome position: 73.74

GC content: 63.35

Gene sequence:

>1656_bases
ATGTCTTCCGCCTTCCGTTTGCCGCTGGACGTGTTTTACGAACGCGAGGCCCGGCACCCGCGTCAGCGTTTTCTGGTGCA
GCCGATCGGCGGCGGGCAGGTCGAGACACTGACCTGGGCCGACGTCGGCCATCAGGCTCGCTGCGCGGCGCACTGGCTGC
GATCCCGGGAATTGCCGCAAGGCAGCCACATCGCCCTGATCTCGAAAAACTGCGCGCACTGGATCATCGCCGATCTGGCG
ATCTGGATGGCCGGGCACGTTTCGGTGCCGCTCTATCCGAACCTCACCGCCGAATCGGTGAATCAGGTGCTGACCCACTC
GGAAAGCGTGCTGGCGTTCATCGGCAAACTCGATGACTGGCCGGGTATGTCGCCAGGCGTGCCGGCGGGCCTGACCACCG
TCAGCCTGCCGCTGCACCCACCGGGCACGTTCGATTTCAACTGGGATGACCTGCAACGCAGCTCGCCGATCCAGGACGAT
CCACGTCCCGCCGCCGAGCAACTGGCGACGATTATTTACACCTCCGGCACCACCGGCCTGCCCAAGGGCGTGATGCACAG
CTTCGCCAATCTCGGATTCGCGACGACGCGCGGTACGCAGCTGTTCGGCCTCAATGAGAACGACCGGCTGCTGTCGTATT
TGCCGCTGTGCCATGTGGCCGAGCGGATGTTCGTCGAACTGGCGTCGATCTACACCGGGCAGACGGTGTTTTTCGCCGAG
AGCCTCGACACCTTCCTCGCCGATCTCAAGCGGGCGCGACCAACGGCGATGTTCGGTGTGCCGCGGATCTGGACCAAGTT
CCAGATGGGTGTCTACAGCAAGATCCCGGCGAAACGTCTGGATTTCCTGCTCGGTCTGCCCTTCATCGGCAAGCGGGTCG
GTCACAAGGTGTTGGCGGGGTTGGGGCTGGATGCCTTGCGCGTAGCGCTGTCTGGCGCGGCGCCGGTGCCGCTGACCTTG
TTGCGCTGGTATCAGAAACTCGGGCTCGACGTGCTGGAGGTCTACGGCATGACCGAAAGCTGCGGTTATTCGCACATCTG
CCTGCCGGGGCAATACAAGGAAGGCTGGATCGGCCGGCCGTGCCCCGAAGTTGAAGTGCGGATCGACGAGTCCGGCGAAG
TGCAGGTGCGCAGCCAGGCGAACATGCTCGGCTATTTCAAGGAACCGCAGAAAACCGCCGAAACTCTCACTGAAGACGGC
TTCCTGCGCACTGGCGACAAGGGCGAGCAGGACGCCGAAGGGCGCTTGCGCCTGACCGGGCGGCTCAAGGAAATCTTCAA
GACCAGCAAGGGCAAATACGTCGCCCCGGCGCCGATCGAAAACCGGCTGGCGGTGCATTCGCGGATCGAACAGGTCTGTG
TGGTCGGTGATGGCCTGAGTGCACCGCTGGGGTTGTGCGTTCTTTCCGCCGTGGGCCGGGAAGAGCCCCGCGCGCCGCTG
CATTCGAGCCTGGAAAAACTGCTGGAGGAGGTCAACGCCGTGCTCGACAAACACGAGCGTTTGCGCCGGCTGGTGGTGGT
CAAGGACAGCTGGGCGGTGGAGAACGGCTTCCTCACGCCGACCCTGAAAATCAAACGCAACATCATCGAAGACACCTACG
GAGCACGCTTCGAAGAATGGAGCGAGCGCAGCGAGGCGGTGCTGTGGCAGGATTGA

Upstream 100 bases:

>100_bases
CAGCCTTAAACATCCCTGAAATTTTTTGTACGAAATAGTCAACCAAGCACTTGCTTGGTTGACTACGCTTGCTCCAGACC
AAAAAACAGGAGCGAGTCGA

Downstream 100 bases:

>100_bases
GCGTCGATCAAAACAACAAAGGAAGCCTGCGATGACCTTGTGGCGCACCACTCCGAACATCGAGCAGTTGAACGCAATCC
AGAAAAACACCATCGGCGAA

Product: AMP-dependent synthetase and ligase

Products: NA

Alternate protein names: Long-chain acyl-CoA synthetase; LACS [H]

Number of amino acids: Translated: 551; Mature: 550

Protein sequence:

>551_residues
MSSAFRLPLDVFYEREARHPRQRFLVQPIGGGQVETLTWADVGHQARCAAHWLRSRELPQGSHIALISKNCAHWIIADLA
IWMAGHVSVPLYPNLTAESVNQVLTHSESVLAFIGKLDDWPGMSPGVPAGLTTVSLPLHPPGTFDFNWDDLQRSSPIQDD
PRPAAEQLATIIYTSGTTGLPKGVMHSFANLGFATTRGTQLFGLNENDRLLSYLPLCHVAERMFVELASIYTGQTVFFAE
SLDTFLADLKRARPTAMFGVPRIWTKFQMGVYSKIPAKRLDFLLGLPFIGKRVGHKVLAGLGLDALRVALSGAAPVPLTL
LRWYQKLGLDVLEVYGMTESCGYSHICLPGQYKEGWIGRPCPEVEVRIDESGEVQVRSQANMLGYFKEPQKTAETLTEDG
FLRTGDKGEQDAEGRLRLTGRLKEIFKTSKGKYVAPAPIENRLAVHSRIEQVCVVGDGLSAPLGLCVLSAVGREEPRAPL
HSSLEKLLEEVNAVLDKHERLRRLVVVKDSWAVENGFLTPTLKIKRNIIEDTYGARFEEWSERSEAVLWQD

Sequences:

>Translated_551_residues
MSSAFRLPLDVFYEREARHPRQRFLVQPIGGGQVETLTWADVGHQARCAAHWLRSRELPQGSHIALISKNCAHWIIADLA
IWMAGHVSVPLYPNLTAESVNQVLTHSESVLAFIGKLDDWPGMSPGVPAGLTTVSLPLHPPGTFDFNWDDLQRSSPIQDD
PRPAAEQLATIIYTSGTTGLPKGVMHSFANLGFATTRGTQLFGLNENDRLLSYLPLCHVAERMFVELASIYTGQTVFFAE
SLDTFLADLKRARPTAMFGVPRIWTKFQMGVYSKIPAKRLDFLLGLPFIGKRVGHKVLAGLGLDALRVALSGAAPVPLTL
LRWYQKLGLDVLEVYGMTESCGYSHICLPGQYKEGWIGRPCPEVEVRIDESGEVQVRSQANMLGYFKEPQKTAETLTEDG
FLRTGDKGEQDAEGRLRLTGRLKEIFKTSKGKYVAPAPIENRLAVHSRIEQVCVVGDGLSAPLGLCVLSAVGREEPRAPL
HSSLEKLLEEVNAVLDKHERLRRLVVVKDSWAVENGFLTPTLKIKRNIIEDTYGARFEEWSERSEAVLWQD
>Mature_550_residues
SSAFRLPLDVFYEREARHPRQRFLVQPIGGGQVETLTWADVGHQARCAAHWLRSRELPQGSHIALISKNCAHWIIADLAI
WMAGHVSVPLYPNLTAESVNQVLTHSESVLAFIGKLDDWPGMSPGVPAGLTTVSLPLHPPGTFDFNWDDLQRSSPIQDDP
RPAAEQLATIIYTSGTTGLPKGVMHSFANLGFATTRGTQLFGLNENDRLLSYLPLCHVAERMFVELASIYTGQTVFFAES
LDTFLADLKRARPTAMFGVPRIWTKFQMGVYSKIPAKRLDFLLGLPFIGKRVGHKVLAGLGLDALRVALSGAAPVPLTLL
RWYQKLGLDVLEVYGMTESCGYSHICLPGQYKEGWIGRPCPEVEVRIDESGEVQVRSQANMLGYFKEPQKTAETLTEDGF
LRTGDKGEQDAEGRLRLTGRLKEIFKTSKGKYVAPAPIENRLAVHSRIEQVCVVGDGLSAPLGLCVLSAVGREEPRAPLH
SSLEKLLEEVNAVLDKHERLRRLVVVKDSWAVENGFLTPTLKIKRNIIEDTYGARFEEWSERSEAVLWQD

Specific function: Unknown

COG id: COG1022

COG function: function code I; Long-chain acyl-CoA synthetases (AMP-forming)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI42794756, Length=561, Percent_Identity=26.5597147950089, Blast_Score=176, Evalue=5e-44,
Organism=Homo sapiens, GI42794760, Length=561, Percent_Identity=26.5597147950089, Blast_Score=176, Evalue=5e-44,
Organism=Homo sapiens, GI42794758, Length=561, Percent_Identity=26.5597147950089, Blast_Score=176, Evalue=5e-44,
Organism=Homo sapiens, GI40807491, Length=580, Percent_Identity=26.8965517241379, Blast_Score=176, Evalue=6e-44,
Organism=Homo sapiens, GI83745141, Length=606, Percent_Identity=26.4026402640264, Blast_Score=171, Evalue=2e-42,
Organism=Homo sapiens, GI57165412, Length=554, Percent_Identity=28.5198555956679, Blast_Score=170, Evalue=3e-42,
Organism=Homo sapiens, GI57165410, Length=554, Percent_Identity=28.7003610108303, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI42794754, Length=614, Percent_Identity=25.5700325732899, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI42794752, Length=614, Percent_Identity=25.5700325732899, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI27477105, Length=591, Percent_Identity=25.0423011844332, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI4758332, Length=589, Percent_Identity=24.9575551782683, Blast_Score=124, Evalue=3e-28,
Organism=Homo sapiens, GI12669909, Length=611, Percent_Identity=24.5499181669394, Blast_Score=124, Evalue=3e-28,
Organism=Homo sapiens, GI156151445, Length=490, Percent_Identity=23.469387755102, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI157311624, Length=322, Percent_Identity=24.5341614906832, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI157311622, Length=322, Percent_Identity=24.5341614906832, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI42544132, Length=492, Percent_Identity=23.3739837398374, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI58082049, Length=309, Percent_Identity=24.5954692556634, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI122937307, Length=557, Percent_Identity=23.5188509874327, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI145693145, Length=444, Percent_Identity=25.4504504504505, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI221142682, Length=458, Percent_Identity=24.8908296943231, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1788107, Length=499, Percent_Identity=23.8476953907816, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1786810, Length=299, Percent_Identity=25.752508361204, Blast_Score=68, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17510401, Length=561, Percent_Identity=27.6292335115865, Blast_Score=177, Evalue=9e-45,
Organism=Caenorhabditis elegans, GI17541856, Length=567, Percent_Identity=27.8659611992945, Blast_Score=173, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17556552, Length=576, Percent_Identity=26.5625, Blast_Score=169, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI193204819, Length=591, Percent_Identity=27.2419627749577, Blast_Score=151, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17564090, Length=452, Percent_Identity=29.4247787610619, Blast_Score=136, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17558820, Length=373, Percent_Identity=27.3458445040214, Blast_Score=131, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI25147511, Length=586, Percent_Identity=25.2559726962457, Blast_Score=129, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17553312, Length=571, Percent_Identity=24.3432574430823, Blast_Score=124, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI32563687, Length=370, Percent_Identity=27.2972972972973, Blast_Score=124, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17531443, Length=507, Percent_Identity=25.8382642998028, Blast_Score=121, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17559526, Length=325, Percent_Identity=28.9230769230769, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17557194, Length=426, Percent_Identity=24.6478873239437, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71994703, Length=472, Percent_Identity=23.3050847457627, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71994690, Length=472, Percent_Identity=23.3050847457627, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71994694, Length=472, Percent_Identity=23.3050847457627, Blast_Score=78, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6324893, Length=474, Percent_Identity=26.7932489451477, Blast_Score=147, Evalue=6e-36,
Organism=Saccharomyces cerevisiae, GI6320852, Length=576, Percent_Identity=26.0416666666667, Blast_Score=143, Evalue=9e-35,
Organism=Saccharomyces cerevisiae, GI6322182, Length=420, Percent_Identity=25.7142857142857, Blast_Score=120, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6323903, Length=421, Percent_Identity=26.1282660332542, Blast_Score=118, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6319699, Length=511, Percent_Identity=23.8747553816047, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI19921316, Length=617, Percent_Identity=26.0940032414911, Blast_Score=176, Evalue=5e-44,
Organism=Drosophila melanogaster, GI281366413, Length=544, Percent_Identity=27.0220588235294, Blast_Score=167, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24666501, Length=544, Percent_Identity=27.0220588235294, Blast_Score=167, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24666497, Length=544, Percent_Identity=27.0220588235294, Blast_Score=167, Evalue=2e-41,
Organism=Drosophila melanogaster, GI17933690, Length=599, Percent_Identity=24.3739565943239, Blast_Score=162, Evalue=6e-40,
Organism=Drosophila melanogaster, GI62471681, Length=437, Percent_Identity=27.6887871853547, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI62471687, Length=437, Percent_Identity=27.6887871853547, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24586634, Length=437, Percent_Identity=27.6887871853547, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI22026970, Length=437, Percent_Identity=27.6887871853547, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI62471679, Length=437, Percent_Identity=27.9176201372998, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI62471683, Length=437, Percent_Identity=27.9176201372998, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI62471685, Length=437, Percent_Identity=27.9176201372998, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24586636, Length=437, Percent_Identity=27.9176201372998, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI62471689, Length=437, Percent_Identity=27.9176201372998, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24581924, Length=518, Percent_Identity=24.3243243243243, Blast_Score=86, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.3 [H]

Molecular weight: Translated: 61230; Mature: 61099

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSAFRLPLDVFYEREARHPRQRFLVQPIGGGQVETLTWADVGHQARCAAHWLRSRELPQ
CCCCCCCCHHHHHHHHHCCCHHHEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHCCCCC
GSHIALISKNCAHWIIADLAIWMAGHVSVPLYPNLTAESVNQVLTHSESVLAFIGKLDDW
CCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHCCCCC
PGMSPGVPAGLTTVSLPLHPPGTFDFNWDDLQRSSPIQDDPRPAAEQLATIIYTSGTTGL
CCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHEEEEEECCCCCC
PKGVMHSFANLGFATTRGTQLFGLNENDRLLSYLPLCHVAERMFVELASIYTGQTVFFAE
CHHHHHHHHHCCCEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHH
SLDTFLADLKRARPTAMFGVPRIWTKFQMGVYSKIPAKRLDFLLGLPFIGKRVGHKVLAG
HHHHHHHHHHHCCCCHHCCCCHHHHHHHHCHHHCCCHHHHHHHHCCCHHHHHHHHHHHHH
LGLDALRVALSGAAPVPLTLLRWYQKLGLDVLEVYGMTESCGYSHICLPGQYKEGWIGRP
CCHHHHHHHHCCCCCCHHHHHHHHHHHCHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCC
CPEVEVRIDESGEVQVRSQANMLGYFKEPQKTAETLTEDGFLRTGDKGEQDAEGRLRLTG
CCCCEEEECCCCCEEEECCCCHHHCCCCHHHHHHHHHCCCCEECCCCCCCCCCCEEEHHH
RLKEIFKTSKGKYVAPAPIENRLAVHSRIEQVCVVGDGLSAPLGLCVLSAVGREEPRAPL
HHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCCCCCHH
HSSLEKLLEEVNAVLDKHERLRRLVVVKDSWAVENGFLTPTLKIKRNIIEDTYGARFEEW
HHHHHHHHHHHHHHHHHHHHHHEEEEEECCCEECCCCCCCHHHHHHHHHHHHHCCHHHHH
SERSEAVLWQD
HHHCCCEECCC
>Mature Secondary Structure 
SSAFRLPLDVFYEREARHPRQRFLVQPIGGGQVETLTWADVGHQARCAAHWLRSRELPQ
CCCCCCCHHHHHHHHHCCCHHHEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHCCCCC
GSHIALISKNCAHWIIADLAIWMAGHVSVPLYPNLTAESVNQVLTHSESVLAFIGKLDDW
CCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHCCCCC
PGMSPGVPAGLTTVSLPLHPPGTFDFNWDDLQRSSPIQDDPRPAAEQLATIIYTSGTTGL
CCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHEEEEEECCCCCC
PKGVMHSFANLGFATTRGTQLFGLNENDRLLSYLPLCHVAERMFVELASIYTGQTVFFAE
CHHHHHHHHHCCCEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHH
SLDTFLADLKRARPTAMFGVPRIWTKFQMGVYSKIPAKRLDFLLGLPFIGKRVGHKVLAG
HHHHHHHHHHHCCCCHHCCCCHHHHHHHHCHHHCCCHHHHHHHHCCCHHHHHHHHHHHHH
LGLDALRVALSGAAPVPLTLLRWYQKLGLDVLEVYGMTESCGYSHICLPGQYKEGWIGRP
CCHHHHHHHHCCCCCCHHHHHHHHHHHCHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCC
CPEVEVRIDESGEVQVRSQANMLGYFKEPQKTAETLTEDGFLRTGDKGEQDAEGRLRLTG
CCCCEEEECCCCCEEEECCCCHHHCCCCHHHHHHHHHCCCCEECCCCCCCCCCCEEEHHH
RLKEIFKTSKGKYVAPAPIENRLAVHSRIEQVCVVGDGLSAPLGLCVLSAVGREEPRAPL
HHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCCCCCHH
HSSLEKLLEEVNAVLDKHERLRRLVVVKDSWAVENGFLTPTLKIKRNIIEDTYGARFEEW
HHHHHHHHHHHHHHHHHHHHHHEEEEEECCCEECCCCCCCHHHHHHHHHHHHHCCHHHHH
SERSEAVLWQD
HHHCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]