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The map label for this gene is ydfD [H]

Identifier: 77460414

GI number: 77460414

Start: 4733378

End: 4734778

Strand: Reverse

Name: ydfD [H]

Synonym: Pfl01_4193

Alternate gene names: 77460414

Gene position: 4734778-4733378 (Counterclockwise)

Preceding gene: 77460415

Following gene: 77460413

Centisome position: 73.54

GC content: 61.31

Gene sequence:

>1401_bases
ATGGAATTGAGAATTGACCGACAGGCGATGGTGCCGGTTGTACAGCAGATTGTTGACGGGTTGACCGAGTGGATCGTGCA
GGAACAGGTGCCGCCGACGACGCGGCTGCCCTCCGTACGACAGATCGCTCGACGCAATCTGCTCAGCCAGTCCTGCGTCA
TGGAGGCTTGCGAGCGTCTGGTGGCGCAGGGAATTCTGGCGTCGCGCCAGGGCTCGGGATTCATGGTGGCGGCGTTGTTG
CCGGATTATTGCCGGGGGAGTAATGGCTCCGAGGCAGGCGACGAGCAGCACGGTCGCGTTACGCAATCGCCCTGGCGCGG
CGGATTGAAGCTGGGCGCTGGTGTCCTGCCGGAGAGTTGGCGTGAGCCGGATGATCTGAGTTATGCGATCCGACAGGTGG
CGCGCGCCGATATGGCCAGCCTGTTCAACTACAACGACCCCCTCGGTCTTCCGGCGTTGCGGGAGCAGATTGCCAAGCGT
CTCGGATTGCTGGATATCAAGGCCCTCGATGAACAGGTGCTGACGACTGCCGGTGCCAGCCACGCTCTGGACCTGATCAT
GCGGACCCTGTTCAAGGCCGGCGATTGCGTGGTGGTCGAAACGCCCGGACATGCGCCGCTGTTCGAACTTTTGCGCTTGC
ACGGCATTCGCATGCTGGAGGTGCGCCGCACTCCGAGCGGTCCGGACATCGAAGCGCTCGAGGCGTTACTGCAACAGTTC
AGGCCGACAGCGCTGTTCATCAACAGTCATCACCACAATCCCACGGGCAGTTGCCTGGCGCCGGCGGTGGCGCGACAAGT
CTTGCAATTGAGCAGAACCTACGATCTGCGGGTGATTGAAGATGATGTCTACGCCGATCTGCACAATGGCAGCGGTACTC
GTCTGGCCGCGCTGGATGACGGGGAGCGGGTGATCTATGTCGGCAGCTTTTCCAAGACGCTGAGCAGCTCGCTACGGGTC
GGTTTTGTCTTGGCCAGTGACAAACTGATCGAGCGTATGGCGCGGGTCAAGATGATCAGTTGCATGGGCACCTCGAGGTT
CTGCGAGGCGGTTCTGGCCGGATTGCTGGCCAGTGGTGCCTATCGAAAACTGGTACAGCGTCAGCGTCAGCGACTTTCCA
CTGATCGTGTGGCTGCCCTTCAGGCGCTGGAGGACGCTGACTGGGAGGTGTTCGGCAAGCCCACGGGCGGCCTGTTCATC
TGGGCACGTTCGCCAGTGGCCGATGAGACACGTTTGCGCGGGCATGCTCTACGCTGCGGTGTTCAGTTGTCCTGCGCAAC
GTCGTTCAGTCCCAGTGGCGAAGCCTGCGACTGGCAGCGGATCAACGTGGCTTACGCCTGTGATCCACGGGCACGGCAGT
TTTTTCGCGATACAGCCATGGATCGACCTCGAACGTTCTGA

Upstream 100 bases:

>100_bases
AATGGTTAGAACGGAGGCTTTTGACGGTTTTGTCGCACAGCCCGAACGGAGCGGCTGTGATTTACTGCCGCCAGCAAAAC
GGACGGGAGTTTGCGTGCTC

Downstream 100 bases:

>100_bases
AAACGACGCGTGCGTAGCTTTTTGCCATTATTCCGACGCCAGAGACTTGTGCTGGTTCAAGGCCGTTGCGAATCTTCGGC
AACAGACTATGGCAGGGGGC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MELRIDRQAMVPVVQQIVDGLTEWIVQEQVPPTTRLPSVRQIARRNLLSQSCVMEACERLVAQGILASRQGSGFMVAALL
PDYCRGSNGSEAGDEQHGRVTQSPWRGGLKLGAGVLPESWREPDDLSYAIRQVARADMASLFNYNDPLGLPALREQIAKR
LGLLDIKALDEQVLTTAGASHALDLIMRTLFKAGDCVVVETPGHAPLFELLRLHGIRMLEVRRTPSGPDIEALEALLQQF
RPTALFINSHHHNPTGSCLAPAVARQVLQLSRTYDLRVIEDDVYADLHNGSGTRLAALDDGERVIYVGSFSKTLSSSLRV
GFVLASDKLIERMARVKMISCMGTSRFCEAVLAGLLASGAYRKLVQRQRQRLSTDRVAALQALEDADWEVFGKPTGGLFI
WARSPVADETRLRGHALRCGVQLSCATSFSPSGEACDWQRINVAYACDPRARQFFRDTAMDRPRTF

Sequences:

>Translated_466_residues
MELRIDRQAMVPVVQQIVDGLTEWIVQEQVPPTTRLPSVRQIARRNLLSQSCVMEACERLVAQGILASRQGSGFMVAALL
PDYCRGSNGSEAGDEQHGRVTQSPWRGGLKLGAGVLPESWREPDDLSYAIRQVARADMASLFNYNDPLGLPALREQIAKR
LGLLDIKALDEQVLTTAGASHALDLIMRTLFKAGDCVVVETPGHAPLFELLRLHGIRMLEVRRTPSGPDIEALEALLQQF
RPTALFINSHHHNPTGSCLAPAVARQVLQLSRTYDLRVIEDDVYADLHNGSGTRLAALDDGERVIYVGSFSKTLSSSLRV
GFVLASDKLIERMARVKMISCMGTSRFCEAVLAGLLASGAYRKLVQRQRQRLSTDRVAALQALEDADWEVFGKPTGGLFI
WARSPVADETRLRGHALRCGVQLSCATSFSPSGEACDWQRINVAYACDPRARQFFRDTAMDRPRTF
>Mature_466_residues
MELRIDRQAMVPVVQQIVDGLTEWIVQEQVPPTTRLPSVRQIARRNLLSQSCVMEACERLVAQGILASRQGSGFMVAALL
PDYCRGSNGSEAGDEQHGRVTQSPWRGGLKLGAGVLPESWREPDDLSYAIRQVARADMASLFNYNDPLGLPALREQIAKR
LGLLDIKALDEQVLTTAGASHALDLIMRTLFKAGDCVVVETPGHAPLFELLRLHGIRMLEVRRTPSGPDIEALEALLQQF
RPTALFINSHHHNPTGSCLAPAVARQVLQLSRTYDLRVIEDDVYADLHNGSGTRLAALDDGERVIYVGSFSKTLSSSLRV
GFVLASDKLIERMARVKMISCMGTSRFCEAVLAGLLASGAYRKLVQRQRQRLSTDRVAALQALEDADWEVFGKPTGGLFI
WARSPVADETRLRGHALRCGVQLSCATSFSPSGEACDWQRINVAYACDPRARQFFRDTAMDRPRTF

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=278, Percent_Identity=25.5395683453237, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI33469970, Length=278, Percent_Identity=25.5395683453237, Blast_Score=95, Evalue=1e-19,
Organism=Escherichia coli, GI1787710, Length=455, Percent_Identity=28.3516483516484, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1790797, Length=470, Percent_Identity=25.3191489361702, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788722, Length=274, Percent_Identity=24.8175182481752, Blast_Score=73, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21356535, Length=381, Percent_Identity=25.9842519685039, Blast_Score=96, Evalue=6e-20,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 51450; Mature: 51450

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELRIDRQAMVPVVQQIVDGLTEWIVQEQVPPTTRLPSVRQIARRNLLSQSCVMEACERL
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VAQGILASRQGSGFMVAALLPDYCRGSNGSEAGDEQHGRVTQSPWRGGLKLGAGVLPESW
HHHHHHHCCCCCCEEEHEECHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCC
REPDDLSYAIRQVARADMASLFNYNDPLGLPALREQIAKRLGLLDIKALDEQVLTTAGAS
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCHH
HALDLIMRTLFKAGDCVVVETPGHAPLFELLRLHGIRMLEVRRTPSGPDIEALEALLQQF
HHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHC
RPTALFINSHHHNPTGSCLAPAVARQVLQLSRTYDLRVIEDDVYADLHNGSGTRLAALDD
CCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCHHHEEECCCCCCEEEEECC
GERVIYVGSFSKTLSSSLRVGFVLASDKLIERMARVKMISCMGTSRFCEAVLAGLLASGA
CCEEEEEECCHHHHHCCCEEEEEEECHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
YRKLVQRQRQRLSTDRVAALQALEDADWEVFGKPTGGLFIWARSPVADETRLRGHALRCG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEECCCCCCHHHHCCHHHHCC
VQLSCATSFSPSGEACDWQRINVAYACDPRARQFFRDTAMDRPRTF
EEEEEECCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MELRIDRQAMVPVVQQIVDGLTEWIVQEQVPPTTRLPSVRQIARRNLLSQSCVMEACERL
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VAQGILASRQGSGFMVAALLPDYCRGSNGSEAGDEQHGRVTQSPWRGGLKLGAGVLPESW
HHHHHHHCCCCCCEEEHEECHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCC
REPDDLSYAIRQVARADMASLFNYNDPLGLPALREQIAKRLGLLDIKALDEQVLTTAGAS
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCHH
HALDLIMRTLFKAGDCVVVETPGHAPLFELLRLHGIRMLEVRRTPSGPDIEALEALLQQF
HHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHC
RPTALFINSHHHNPTGSCLAPAVARQVLQLSRTYDLRVIEDDVYADLHNGSGTRLAALDD
CCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCHHHEEECCCCCCEEEEECC
GERVIYVGSFSKTLSSSLRVGFVLASDKLIERMARVKMISCMGTSRFCEAVLAGLLASGA
CCEEEEEECCHHHHHCCCEEEEEEECHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
YRKLVQRQRQRLSTDRVAALQALEDADWEVFGKPTGGLFIWARSPVADETRLRGHALRCG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEECCCCCCHHHHCCHHHHCC
VQLSCATSFSPSGEACDWQRINVAYACDPRARQFFRDTAMDRPRTF
EEEEEECCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]