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The map label for this gene is ycfH [H]

Identifier: 77460370

GI number: 77460370

Start: 4687562

End: 4688347

Strand: Reverse

Name: ycfH [H]

Synonym: Pfl01_4149

Alternate gene names: 77460370

Gene position: 4688347-4687562 (Counterclockwise)

Preceding gene: 77460371

Following gene: 77460369

Centisome position: 72.82

GC content: 61.96

Gene sequence:

>786_bases
ATGCTCGTAGATTCCCATTGTCATCTTGATCGCCTCGACCTCGCTGCTCACGACGGTTCCCTGGATGCCGCGCTGGATGC
GGCCCGCGAACGCGGCGTCGGGCATTTCCTGTGCATCGGCGTCAGCGCCGACAACGCGGCCGATGTCAAAGCCTTGGCCG
AGCGTTACGACGACGTCGATTGCTCGGTCGGCGTGCATCCGCTGGATGTGCAGCCGGGCGCGGCGCCGGCGCTGGACTGG
CTGCTGCACGAGCTCAATCACCCGAAAGTGGTAGCGATCGGTGAAACCGGTCTGGACTATCACTATGAGCCGGAAGCCGC
CGAGCTGCAGCAGGAATCGTTCCGATTGCACCTGCAAGCTGCGCAGCAGACCGGCAAACCGGTGATCATCCACACCCGTG
GCGCCCGCGCCGACACACTCGAACTTTTGCGCGAAGCCGCGTTGCCTCAGGCGGGTGTGCTGCATTGCTTCACCGAAGAC
TGGGAAATGGCCAAGGTGGCACTGGACATGGGTTATTACATTTCCCTGTCGGGCATCGTCACCTTCCGCAACGCCGATGC
GTTGCGCGATGTGGCGAGCAAGGTTCCGGCCGATCGGCTGCTGGTTGAGACCGATTCGCCGTATCTGGCGCCGATCCCGT
ATCGCGGCAAACCGAACCTGCCGCAATACGTGCGGGAAGTGGCAGAGTTTCTGGCGATGCTGCGCGGCGAGAACTATGAG
CGTTTTGCCGAGCAGACCACCGAGAACTTCAAGCGACTGTTTCCGCTGGCGAATGTAAAAGCCTGA

Upstream 100 bases:

>100_bases
CGATGGCGACAACACTGCGCGCAGTCGCATCGAAACTCATCTGGCCGGAGCCCTGAAATCCGACCGTCCCACTCATACGA
TGTAAGTTGCAGTCCTTTTT

Downstream 100 bases:

>100_bases
ATCGCAGGCAAAAAAAACCCGGGTTCTGGGGGGTGAATCCGGGTTAAGACCATTAGGAGTAAAACAAAGGCACGCGGTCC
CTTGGTACCTTTACCGGCGC

Product: TatD-like deoxyribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MLVDSHCHLDRLDLAAHDGSLDAALDAARERGVGHFLCIGVSADNAADVKALAERYDDVDCSVGVHPLDVQPGAAPALDW
LLHELNHPKVVAIGETGLDYHYEPEAAELQQESFRLHLQAAQQTGKPVIIHTRGARADTLELLREAALPQAGVLHCFTED
WEMAKVALDMGYYISLSGIVTFRNADALRDVASKVPADRLLVETDSPYLAPIPYRGKPNLPQYVREVAEFLAMLRGENYE
RFAEQTTENFKRLFPLANVKA

Sequences:

>Translated_261_residues
MLVDSHCHLDRLDLAAHDGSLDAALDAARERGVGHFLCIGVSADNAADVKALAERYDDVDCSVGVHPLDVQPGAAPALDW
LLHELNHPKVVAIGETGLDYHYEPEAAELQQESFRLHLQAAQQTGKPVIIHTRGARADTLELLREAALPQAGVLHCFTED
WEMAKVALDMGYYISLSGIVTFRNADALRDVASKVPADRLLVETDSPYLAPIPYRGKPNLPQYVREVAEFLAMLRGENYE
RFAEQTTENFKRLFPLANVKA
>Mature_261_residues
MLVDSHCHLDRLDLAAHDGSLDAALDAARERGVGHFLCIGVSADNAADVKALAERYDDVDCSVGVHPLDVQPGAAPALDW
LLHELNHPKVVAIGETGLDYHYEPEAAELQQESFRLHLQAAQQTGKPVIIHTRGARADTLELLREAALPQAGVLHCFTED
WEMAKVALDMGYYISLSGIVTFRNADALRDVASKVPADRLLVETDSPYLAPIPYRGKPNLPQYVREVAEFLAMLRGENYE
RFAEQTTENFKRLFPLANVKA

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI225903424, Length=271, Percent_Identity=30.2583025830258, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI110349734, Length=267, Percent_Identity=29.5880149812734, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI110349730, Length=267, Percent_Identity=29.2134831460674, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI226061853, Length=273, Percent_Identity=29.3040293040293, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI14042943, Length=275, Percent_Identity=25.8181818181818, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI226061614, Length=259, Percent_Identity=27.7992277992278, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI225903439, Length=249, Percent_Identity=25.7028112449799, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI226061595, Length=229, Percent_Identity=28.82096069869, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1787342, Length=256, Percent_Identity=52.734375, Blast_Score=241, Evalue=3e-65,
Organism=Escherichia coli, GI87082439, Length=255, Percent_Identity=32.9411764705882, Blast_Score=130, Evalue=9e-32,
Organism=Escherichia coli, GI48994985, Length=243, Percent_Identity=33.3333333333333, Blast_Score=115, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17559024, Length=272, Percent_Identity=30.1470588235294, Blast_Score=110, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI17543026, Length=294, Percent_Identity=25.8503401360544, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71980746, Length=269, Percent_Identity=25.2788104089219, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17565396, Length=172, Percent_Identity=30.8139534883721, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24648690, Length=213, Percent_Identity=32.8638497652582, Blast_Score=94, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24586117, Length=210, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221330018, Length=212, Percent_Identity=29.2452830188679, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 28806; Mature: 28806

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS01137 TATD_1 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVDSHCHLDRLDLAAHDGSLDAALDAARERGVGHFLCIGVSADNAADVKALAERYDDVD
CEECCCCCCCHHHHCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCCC
CSVGVHPLDVQPGAAPALDWLLHELNHPKVVAIGETGLDYHYEPEAAELQQESFRLHLQA
CCCCCEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHH
AQQTGKPVIIHTRGARADTLELLREAALPQAGVLHCFTEDWEMAKVALDMGYYISLSGIV
HHHCCCEEEEEECCCCHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHCCEEEEEEEEE
TFRNADALRDVASKVPADRLLVETDSPYLAPIPYRGKPNLPQYVREVAEFLAMLRGENYE
EECCHHHHHHHHHHCCCCCEEEECCCCEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCHH
RFAEQTTENFKRLFPLANVKA
HHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MLVDSHCHLDRLDLAAHDGSLDAALDAARERGVGHFLCIGVSADNAADVKALAERYDDVD
CEECCCCCCCHHHHCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCCC
CSVGVHPLDVQPGAAPALDWLLHELNHPKVVAIGETGLDYHYEPEAAELQQESFRLHLQA
CCCCCEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHH
AQQTGKPVIIHTRGARADTLELLREAALPQAGVLHCFTEDWEMAKVALDMGYYISLSGIV
HHHCCCEEEEEECCCCHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHCCEEEEEEEEE
TFRNADALRDVASKVPADRLLVETDSPYLAPIPYRGKPNLPQYVREVAEFLAMLRGENYE
EECCHHHHHHHHHHCCCCCEEEECCCCEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCHH
RFAEQTTENFKRLFPLANVKA
HHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]