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The map label for this gene is etfA [H]

Identifier: 77460337

GI number: 77460337

Start: 4656859

End: 4657788

Strand: Reverse

Name: etfA [H]

Synonym: Pfl01_4116

Alternate gene names: 77460337

Gene position: 4657788-4656859 (Counterclockwise)

Preceding gene: 77460338

Following gene: 77460336

Centisome position: 72.34

GC content: 60.86

Gene sequence:

>930_bases
ATGACTATCTTGGTAATCGCCGAACACGACAACAAGGTGCTGGCTCCGGCCACCCTGAACACCGTGGCTGCCGCTGCCAA
AATCGGCGGCGACATCCACGTTCTGGTTGCAGGTCAGGGCGCTGGCGCCGTGGCTGAAGCCGCTGCGAAAATCGCTGGCG
TGAGCAAAGTCCTGAACGCTGACAATGCTGCCTACGCGCATCAGCTGCCGGAAAACGTTGCTCCTCTGGTAGCCGAACTG
GGCGCTGGCTACAGCCACATCCTGGCTGCCGCTACTTCCAACGGCAAAAACATCCTGCCGCGCGTTGCCGCCCAGCTGGA
CGTTGACCAGATCTCCGAGATCATCTCGGTAGAAAGCGCTGACACCTTCAAGCGTCCGATCTACGCCGGTAACGCCATCG
CTACCGTGCAATCGACCGCAGCGATCAAAGTGATCACCGTGCGTGCCACCGGTTTCGACCCGGTTGCCGCTGAAGGCGGT
TCGGCTGCCGTTGAAGCGGTTGCTGCTGCTCACAACGCCGGCACTTCCAGCTTCGTCAGCGAAGAACTGGCCAAGTCCGA
TCGTCCTGAGCTGACCGCTGCCAAAATCGTCGTTTCCGGCGGCCGCGGCATGCAGAACGGCGATAACTTCAAACACCTCT
ACGCGCTCGCCGACAAGCTGGGCGCTGCTGTGGGTGCTTCGCGCGCCGCGGTCGACGCAGGTTTCGTACCGAACGACATG
CAGGTCGGTCAGACCGGCAAGATCGTTGCGCCACAGCTGTACATCGCCGTCGGTATCTCCGGCGCGATCCAGCACCTGGC
CGGCATGAAAGACTCCAAAGTGATCGTTGCGATCAACAAGGACGAAGAAGCGCCGATCTTCCAGGTGGCCGATTACGGTC
TGGTGGCGGATCTGTTCGAAGCCGTACCTGAGCTGGAGAAGCTGGTCTAA

Upstream 100 bases:

>100_bases
TGAAAGTCGAAGCGCCAGCTGCACGCAGCGCGGGCATCAAGGTCAAGTCGGTGGCTGAACTGGTCGAGAAACTGAAAAAC
GAAGCGAAGGTAATCTGATC

Downstream 100 bases:

>100_bases
TCCGGCCGCTTCACTTATAAAGAGCCCGACCTTTTGGTCGGGCTTTTTTTTGTCTGGGATTTGAGTGGGAGCGTTTCGCC
ATGGATCTGCATCGTCGGTA

Product: electron transfer flavoprotein subunit alpha and beta

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MTILVIAEHDNKVLAPATLNTVAAAAKIGGDIHVLVAGQGAGAVAEAAAKIAGVSKVLNADNAAYAHQLPENVAPLVAEL
GAGYSHILAAATSNGKNILPRVAAQLDVDQISEIISVESADTFKRPIYAGNAIATVQSTAAIKVITVRATGFDPVAAEGG
SAAVEAVAAAHNAGTSSFVSEELAKSDRPELTAAKIVVSGGRGMQNGDNFKHLYALADKLGAAVGASRAAVDAGFVPNDM
QVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFEAVPELEKLV

Sequences:

>Translated_309_residues
MTILVIAEHDNKVLAPATLNTVAAAAKIGGDIHVLVAGQGAGAVAEAAAKIAGVSKVLNADNAAYAHQLPENVAPLVAEL
GAGYSHILAAATSNGKNILPRVAAQLDVDQISEIISVESADTFKRPIYAGNAIATVQSTAAIKVITVRATGFDPVAAEGG
SAAVEAVAAAHNAGTSSFVSEELAKSDRPELTAAKIVVSGGRGMQNGDNFKHLYALADKLGAAVGASRAAVDAGFVPNDM
QVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFEAVPELEKLV
>Mature_308_residues
TILVIAEHDNKVLAPATLNTVAAAAKIGGDIHVLVAGQGAGAVAEAAAKIAGVSKVLNADNAAYAHQLPENVAPLVAELG
AGYSHILAAATSNGKNILPRVAAQLDVDQISEIISVESADTFKRPIYAGNAIATVQSTAAIKVITVRATGFDPVAAEGGS
AAVEAVAAAHNAGTSSFVSEELAKSDRPELTAAKIVVSGGRGMQNGDNFKHLYALADKLGAAVGASRAAVDAGFVPNDMQ
VGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFEAVPELEKLV

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=310, Percent_Identity=60.9677419354839, Blast_Score=380, Evalue=1e-105,
Organism=Homo sapiens, GI189181759, Length=274, Percent_Identity=62.043795620438, Blast_Score=339, Evalue=2e-93,
Organism=Escherichia coli, GI1787990, Length=228, Percent_Identity=34.2105263157895, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1786226, Length=230, Percent_Identity=33.9130434782609, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI87082157, Length=209, Percent_Identity=33.4928229665072, Blast_Score=79, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17506929, Length=307, Percent_Identity=61.2377850162867, Blast_Score=363, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6325261, Length=292, Percent_Identity=46.5753424657534, Blast_Score=252, Evalue=6e-68,
Organism=Drosophila melanogaster, GI17136898, Length=307, Percent_Identity=67.7524429967427, Blast_Score=402, Evalue=1e-112,
Organism=Drosophila melanogaster, GI24652801, Length=307, Percent_Identity=67.7524429967427, Blast_Score=402, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31343; Mature: 31212

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTILVIAEHDNKVLAPATLNTVAAAAKIGGDIHVLVAGQGAGAVAEAAAKIAGVSKVLNA
CEEEEEEECCCEEECCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCC
DNAAYAHQLPENVAPLVAELGAGYSHILAAATSNGKNILPRVAAQLDVDQISEIISVESA
CCCHHHHHCCHHHHHHHHHHCCCHHHHEEEECCCCCHHHHHHHHHCCHHHHHHHHHCCCC
DTFKRPIYAGNAIATVQSTAAIKVITVRATGFDPVAAEGGSAAVEAVAAAHNAGTSSFVS
HHHHCCCCCCCEEEEEECCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCHHHHH
EELAKSDRPELTAAKIVVSGGRGMQNGDNFKHLYALADKLGAAVGASRAAVDAGFVPNDM
HHHHHCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCC
QVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFE
CCCCCCCEECCEEEEEECHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCHHHHHHHH
AVPELEKLV
HHHHHHHCC
>Mature Secondary Structure 
TILVIAEHDNKVLAPATLNTVAAAAKIGGDIHVLVAGQGAGAVAEAAAKIAGVSKVLNA
EEEEEEECCCEEECCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCC
DNAAYAHQLPENVAPLVAELGAGYSHILAAATSNGKNILPRVAAQLDVDQISEIISVESA
CCCHHHHHCCHHHHHHHHHHCCCHHHHEEEECCCCCHHHHHHHHHCCHHHHHHHHHCCCC
DTFKRPIYAGNAIATVQSTAAIKVITVRATGFDPVAAEGGSAAVEAVAAAHNAGTSSFVS
HHHHCCCCCCCEEEEEECCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCHHHHH
EELAKSDRPELTAAKIVVSGGRGMQNGDNFKHLYALADKLGAAVGASRAAVDAGFVPNDM
HHHHHCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCC
QVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFE
CCCCCCCEECCEEEEEECHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCHHHHHHHH
AVPELEKLV
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]