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The map label for this gene is hisC2 [H]

Identifier: 77460296

GI number: 77460296

Start: 4604316

End: 4605428

Strand: Reverse

Name: hisC2 [H]

Synonym: Pfl01_4075

Alternate gene names: 77460296

Gene position: 4605428-4604316 (Counterclockwise)

Preceding gene: 77460297

Following gene: 77460295

Centisome position: 71.53

GC content: 63.97

Gene sequence:

>1113_bases
ATGAGTGGCAACTTCCTCGCTCTGGCACAGCCGGGCGTGCAGCAACTTTCGCCATACGTGCCGGGCAAGCCCGTGGACGA
ACTGGCCCGCGAGCTGGACCTGGATCCGGCAAGTATCGTCAAACTGGCGAGCAACGAAAACCCGTTGGGCGCGAGCCCGA
AAGCGCTGGCCGCGATCCGCGAGGCGCTGGACGAACTGACCCGCTATCCGGACGGTAACGGTTTCGCACTGAAATCCCTG
CTGGCCGAGCAGTGCCGTGTCGAGCTGAACCAAGTGACTTTGGGCAACGGTTCCAACGACATTCTCGAGCTGGTGGCGCG
CGCCTATCTGGCGCCGGGCCTGAATGCGGTGTTCAGCGAGCACGCGTTCGCGGTTTACCCGATCGCGACCCAGGCAGTCG
GCGCTCAGGCCAAGGTCGTTCCAGCCAAAGAGTGGGGGCACGATTTGCCAGCGATGCTGGCGGCCATCGATGCGAACACC
CGTGTCGTGTTCATCGCCAACCCGAACAACCCGACCGGTACCTGGTTCGGCGCCGAAGCGCTGGACGACTTCCTGCAGGA
CGTGCCAGAGCACGTGCTGGTGGTGCTGGACGAGGCGTACATCGAATACGCCGAAGGCAGTGATCTGCCGGATGGTCTGG
ACTTCCTCGCGGCTTATCCGAACCTGCTGGTCTCGCGCACGTTCTCCAAGGCCTACGGTCTGGCGGCGCTGCGCGTCGGT
TACGGCCTGTCCACCCCGGTGGTGGCGGACGTGCTGAACCGTGTACGCCAGCCGTTCAACGTCAACAGCCTGGCCCTGGC
CGCGGCGTGTGCGGCGTTGAAAGACGAGGAATATCTGGCGCAGAGCCGCCAGCTCAACGAATCCGGCATGCAACAGCTGG
AGGCGGGTTTTCGCGAGCTGGGTCTGAGCTGGATTCCGTCCAAGGGCAACTTTATCTGCGTCGACCTTGGTCAGGTGGCG
GCTCCGGTGTTCCAGGGCCTGCTGCGTGAAGGCGTGATTGTGCGTCCGGTGGCCAACTACGGCATGCCGAACCATCTGCG
GGTGACCATCGGTCTGCCGGCGGAAAACAGCCGCTTCCTCGAAGCGCTGCGCAAGGTTCTGGCTCGTGGGTGA

Upstream 100 bases:

>100_bases
TCCGCTGATCAAGGGTGTACTGGAAAAGATCAGTCAGGAAGCAGTAGCACTCAAGGTGCTGGGTTCCTACCCGAAAGCAG
TTCTTTAAGGGGTGGTAGCA

Downstream 100 bases:

>100_bases
TGTCACTGCGCTGCAATCTGCTGCACCTATGATCGGGCGCCTGGTGGTGGTTGGTCTGGGGTTGATCGGTGGTTCGTTTG
CCAAAGGCTTGCGTGAAAGC

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase 2 [H]

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MSGNFLALAQPGVQQLSPYVPGKPVDELARELDLDPASIVKLASNENPLGASPKALAAIREALDELTRYPDGNGFALKSL
LAEQCRVELNQVTLGNGSNDILELVARAYLAPGLNAVFSEHAFAVYPIATQAVGAQAKVVPAKEWGHDLPAMLAAIDANT
RVVFIANPNNPTGTWFGAEALDDFLQDVPEHVLVVLDEAYIEYAEGSDLPDGLDFLAAYPNLLVSRTFSKAYGLAALRVG
YGLSTPVVADVLNRVRQPFNVNSLALAAACAALKDEEYLAQSRQLNESGMQQLEAGFRELGLSWIPSKGNFICVDLGQVA
APVFQGLLREGVIVRPVANYGMPNHLRVTIGLPAENSRFLEALRKVLARG

Sequences:

>Translated_370_residues
MSGNFLALAQPGVQQLSPYVPGKPVDELARELDLDPASIVKLASNENPLGASPKALAAIREALDELTRYPDGNGFALKSL
LAEQCRVELNQVTLGNGSNDILELVARAYLAPGLNAVFSEHAFAVYPIATQAVGAQAKVVPAKEWGHDLPAMLAAIDANT
RVVFIANPNNPTGTWFGAEALDDFLQDVPEHVLVVLDEAYIEYAEGSDLPDGLDFLAAYPNLLVSRTFSKAYGLAALRVG
YGLSTPVVADVLNRVRQPFNVNSLALAAACAALKDEEYLAQSRQLNESGMQQLEAGFRELGLSWIPSKGNFICVDLGQVA
APVFQGLLREGVIVRPVANYGMPNHLRVTIGLPAENSRFLEALRKVLARG
>Mature_369_residues
SGNFLALAQPGVQQLSPYVPGKPVDELARELDLDPASIVKLASNENPLGASPKALAAIREALDELTRYPDGNGFALKSLL
AEQCRVELNQVTLGNGSNDILELVARAYLAPGLNAVFSEHAFAVYPIATQAVGAQAKVVPAKEWGHDLPAMLAAIDANTR
VVFIANPNNPTGTWFGAEALDDFLQDVPEHVLVVLDEAYIEYAEGSDLPDGLDFLAAYPNLLVSRTFSKAYGLAALRVGY
GLSTPVVADVLNRVRQPFNVNSLALAAACAALKDEEYLAQSRQLNESGMQQLEAGFRELGLSWIPSKGNFICVDLGQVAA
PVFQGLLREGVIVRPVANYGMPNHLRVTIGLPAENSRFLEALRKVLARG

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=364, Percent_Identity=28.021978021978, Blast_Score=128, Evalue=6e-31,
Organism=Saccharomyces cerevisiae, GI6322075, Length=398, Percent_Identity=26.1306532663317, Blast_Score=118, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001917
- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 39657; Mature: 39525

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS00599 AA_TRANSFER_CLASS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGNFLALAQPGVQQLSPYVPGKPVDELARELDLDPASIVKLASNENPLGASPKALAAIR
CCCCEEEEECCCHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHHHH
EALDELTRYPDGNGFALKSLLAEQCRVELNQVTLGNGSNDILELVARAYLAPGLNAVFSE
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHCCCHHHHHHC
HAFAVYPIATQAVGAQAKVVPAKEWGHDLPAMLAAIDANTRVVFIANPNNPTGTWFGAEA
CCEEEEEHHHHHCCCCEEEEEHHHHCCHHHHHHHHHCCCCEEEEEECCCCCCCCEECHHH
LDDFLQDVPEHVLVVLDEAYIEYAEGSDLPDGLDFLAAYPNLLVSRTFSKAYGLAALRVG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
YGLSTPVVADVLNRVRQPFNVNSLALAAACAALKDEEYLAQSRQLNESGMQQLEAGFREL
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHC
GLSWIPSKGNFICVDLGQVAAPVFQGLLREGVIVRPVANYGMPNHLRVTIGLPAENSRFL
CCEECCCCCCEEEEEHHHHHHHHHHHHHHCCEEEEEHHHCCCCCCEEEEEECCCCCHHHH
EALRKVLARG
HHHHHHHCCC
>Mature Secondary Structure 
SGNFLALAQPGVQQLSPYVPGKPVDELARELDLDPASIVKLASNENPLGASPKALAAIR
CCCEEEEECCCHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHHHH
EALDELTRYPDGNGFALKSLLAEQCRVELNQVTLGNGSNDILELVARAYLAPGLNAVFSE
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHCCCHHHHHHC
HAFAVYPIATQAVGAQAKVVPAKEWGHDLPAMLAAIDANTRVVFIANPNNPTGTWFGAEA
CCEEEEEHHHHHCCCCEEEEEHHHHCCHHHHHHHHHCCCCEEEEEECCCCCCCCEECHHH
LDDFLQDVPEHVLVVLDEAYIEYAEGSDLPDGLDFLAAYPNLLVSRTFSKAYGLAALRVG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
YGLSTPVVADVLNRVRQPFNVNSLALAAACAALKDEEYLAQSRQLNESGMQQLEAGFREL
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHC
GLSWIPSKGNFICVDLGQVAAPVFQGLLREGVIVRPVANYGMPNHLRVTIGLPAENSRFL
CCEECCCCCCEEEEEHHHHHHHHHHHHHHCCEEEEEHHHCCCCCCEEEEEECCCCCHHHH
EALRKVLARG
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA