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The map label for this gene is aroA [H]

Identifier: 77460295

GI number: 77460295

Start: 4602080

End: 4604287

Strand: Reverse

Name: aroA [H]

Synonym: Pfl01_4074

Alternate gene names: 77460295

Gene position: 4604287-4602080 (Counterclockwise)

Preceding gene: 77460296

Following gene: 77460294

Centisome position: 71.51

GC content: 63.77

Gene sequence:

>2208_bases
ATGATCGGGCGCCTGGTGGTGGTTGGTCTGGGGTTGATCGGTGGTTCGTTTGCCAAAGGCTTGCGTGAAAGCGGCGTCTG
TCGCGAAGTGGTCGGGGTCGATCTCGACCCGCAATCGCGCAAGCTGGCGGTCGAGTTGGGCGTGGTGGATCGTTGCGAAG
ACGACCTGGTGGCGGCTTGCCGGGGCGCGGACGTGATCCAGTTGGCGGTGCCGATCCTGGCCATGGAAAAAGTGCTGGCC
CGTCTGGCCGGCATGGATCTGGGGCAGGCGATCCTGACGGATGTCGGCAGCGCCAAGGGCAATGTGGTGCGTGCGGCGAC
CGAAGCGTTCGGCGGCATGCCGGCGCGTTTCGTGCCGGGCCATCCGATTGCCGGCTCCGAGCAGAGCGGGGTGGAAGCTT
CCAACTCAGAGCTGTTCCGTCGTCATAAAGTGATTCTGACCCCGTTGGAGCAGACCGATCCGGCCGCCCTGGCCGTGGTC
GATCGCTTGTGGCGTGAGCTGGGCGCCGACGTCGAGCACATGCAGGTCGAACGTCACGATGAAGTGCTGGCCGCGACCAG
TCATCTGCCGCACCTGCTGGCCTTCGGTCTGGTCGATTCACTGGCCAAGCGCAATGAAAACCTTGAGATCTTCCGTTACG
CTGCGGGCGGTTTCCGTGATTTCACAAGAATCGCCGGAAGCGACCCGGTCATGTGGCATGACATCTTTCTCGCCAACCGC
GAGGCTGTCCTGCGCACACTCGATACATTTCGCAGCGACCTCGACGCCTTGCGCGACGCGGTCGATGCAGGGGATGGGCA
CCAATTGTTGGGCGTCTTCACGCGCGCCCGGGTTGCCCGCGAGCATTTCAGTAAAATCCTGGCCCGCAGGGCCTATGTGG
ACGCTATGAATTCCAACGATCTGATTTTCCTGGCTCAACCTGGTGGCCGCCTGTCCGGTCGGATTCGCGTACCGGGTGAC
AAATCGATTTCCCACCGTTCGATCATGCTCGGTTCCCTGGCTGAAGGCGTCACCGAAGTCGAAGGCTTCCTCGAGGGCGA
AGACGCCCTGGCGACCTTGCAGGCGTTCCGCGACATGGGCGTGGTCATCGAAGGCCCGCATCACGGCCGCGTGACCATCC
ACGGTGTCGGCCTGCATGGCCTGAAGCCTGCGCCGGGCCCGATCTATCTGGGCAACTCCGGCACTTCGATGCGCCTGCTG
TCCGGCCTGCTGGCCGCGCAGGATTTCGACAGCACCCTAACCGGTGACGCTTCGTTGTCCAAGCGCCCGATGAATCGCGT
CGCCAACCCGCTGCGGGAAATGGGCGCCGTGATCGAAACCGCTGCCGAGGGTCGTCCACCGATGACCATTCGTGGCGGTC
ACAAGCTTAAAGGCCTGACCTACACCATGCCGATGGCCAGTGCTCAGGTTAAATCCTGCCTGCTGCTGGCGGGTCTGTAC
GCCGAAGGTAAGACCACCGTGACCGAGCCGGCACCGACCCGTGATCACACCGAGCGTATGCTGCGCGGCTTTGGCTATCC
GGTGAGCGTCAACGGTGCCACGGCATCGGTTGAGTCTGGTGGCAAGCTGACCGCGACCCACATCGAAGTGCCTGGCGACA
TCTCGTCGTCGGCGTTCTTCCTGGTGGCCGCATCGATCGCTGAAGGCTCGGAGCTGGTGCTCGAGCACGTCGGCATCAAC
CCGACCCGCACCGGCGTGATCGACATCCTGCGTCTGATGGGCGCCGACATCACTCTGGAAAACCAGCGTGAAGTGGGTGG
CGAGCCGGTTGCCGACCTGCGTGTGCGAGCAGCTAAACTCAAGGGTATCGAGATTCCGGAAGCGCTGGTTCCACTGGCCA
TCGACGAATTCCCGGTGCTGTTCGTGGCCGCGGCCTGTGCTGAAGGGCGCACCGTGCTGACCGGCGCCGAAGAGCTGCGG
GTCAAGGAGTCTGACCGTATCCAGGTCATGGCGGACGGTCTGCTGGCGCTGGGCGTCAAGTGCGAACCGACCCCGGACGG
CATCATCATCGACGGCGGCCAGATCGGCGGCGGCGAAGTGCATGGTCATGGCGATCACCGTATCGCGATGGCTTTCAGCG
TGGCCTCGCTGCGCGCCACGGCACCGATCCGCATCCATGACTGCGCCAACGTCGCGACATCGTTCCCGAACTTCCTGGCG
CTCTGCGCGCAGGTCGGCATTCGTGTGGCGCAAGAGGCTCAGTCGTGA

Upstream 100 bases:

>100_bases
GTGACCATCGGTCTGCCGGCGGAAAACAGCCGCTTCCTCGAAGCGCTGCGCAAGGTTCTGGCTCGTGGGTGATGTCACTG
CGCTGCAATCTGCTGCACCT

Downstream 100 bases:

>100_bases
ACAACATTGCACCGGTCATCACCATCGACGGGCCAAGCGGCTCGGGCAAAGGCACCGTAGCCGGGATTCTGGCCAAGCGT
CTTGGCTGGAACCTGCTGGA

Product: bifunctional cyclohexadienyl dehydrogenase/ 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 735; Mature: 735

Protein sequence:

>735_residues
MIGRLVVVGLGLIGGSFAKGLRESGVCREVVGVDLDPQSRKLAVELGVVDRCEDDLVAACRGADVIQLAVPILAMEKVLA
RLAGMDLGQAILTDVGSAKGNVVRAATEAFGGMPARFVPGHPIAGSEQSGVEASNSELFRRHKVILTPLEQTDPAALAVV
DRLWRELGADVEHMQVERHDEVLAATSHLPHLLAFGLVDSLAKRNENLEIFRYAAGGFRDFTRIAGSDPVMWHDIFLANR
EAVLRTLDTFRSDLDALRDAVDAGDGHQLLGVFTRARVAREHFSKILARRAYVDAMNSNDLIFLAQPGGRLSGRIRVPGD
KSISHRSIMLGSLAEGVTEVEGFLEGEDALATLQAFRDMGVVIEGPHHGRVTIHGVGLHGLKPAPGPIYLGNSGTSMRLL
SGLLAAQDFDSTLTGDASLSKRPMNRVANPLREMGAVIETAAEGRPPMTIRGGHKLKGLTYTMPMASAQVKSCLLLAGLY
AEGKTTVTEPAPTRDHTERMLRGFGYPVSVNGATASVESGGKLTATHIEVPGDISSSAFFLVAASIAEGSELVLEHVGIN
PTRTGVIDILRLMGADITLENQREVGGEPVADLRVRAAKLKGIEIPEALVPLAIDEFPVLFVAAACAEGRTVLTGAEELR
VKESDRIQVMADGLLALGVKCEPTPDGIIIDGGQIGGGEVHGHGDHRIAMAFSVASLRATAPIRIHDCANVATSFPNFLA
LCAQVGIRVAQEAQS

Sequences:

>Translated_735_residues
MIGRLVVVGLGLIGGSFAKGLRESGVCREVVGVDLDPQSRKLAVELGVVDRCEDDLVAACRGADVIQLAVPILAMEKVLA
RLAGMDLGQAILTDVGSAKGNVVRAATEAFGGMPARFVPGHPIAGSEQSGVEASNSELFRRHKVILTPLEQTDPAALAVV
DRLWRELGADVEHMQVERHDEVLAATSHLPHLLAFGLVDSLAKRNENLEIFRYAAGGFRDFTRIAGSDPVMWHDIFLANR
EAVLRTLDTFRSDLDALRDAVDAGDGHQLLGVFTRARVAREHFSKILARRAYVDAMNSNDLIFLAQPGGRLSGRIRVPGD
KSISHRSIMLGSLAEGVTEVEGFLEGEDALATLQAFRDMGVVIEGPHHGRVTIHGVGLHGLKPAPGPIYLGNSGTSMRLL
SGLLAAQDFDSTLTGDASLSKRPMNRVANPLREMGAVIETAAEGRPPMTIRGGHKLKGLTYTMPMASAQVKSCLLLAGLY
AEGKTTVTEPAPTRDHTERMLRGFGYPVSVNGATASVESGGKLTATHIEVPGDISSSAFFLVAASIAEGSELVLEHVGIN
PTRTGVIDILRLMGADITLENQREVGGEPVADLRVRAAKLKGIEIPEALVPLAIDEFPVLFVAAACAEGRTVLTGAEELR
VKESDRIQVMADGLLALGVKCEPTPDGIIIDGGQIGGGEVHGHGDHRIAMAFSVASLRATAPIRIHDCANVATSFPNFLA
LCAQVGIRVAQEAQS
>Mature_735_residues
MIGRLVVVGLGLIGGSFAKGLRESGVCREVVGVDLDPQSRKLAVELGVVDRCEDDLVAACRGADVIQLAVPILAMEKVLA
RLAGMDLGQAILTDVGSAKGNVVRAATEAFGGMPARFVPGHPIAGSEQSGVEASNSELFRRHKVILTPLEQTDPAALAVV
DRLWRELGADVEHMQVERHDEVLAATSHLPHLLAFGLVDSLAKRNENLEIFRYAAGGFRDFTRIAGSDPVMWHDIFLANR
EAVLRTLDTFRSDLDALRDAVDAGDGHQLLGVFTRARVAREHFSKILARRAYVDAMNSNDLIFLAQPGGRLSGRIRVPGD
KSISHRSIMLGSLAEGVTEVEGFLEGEDALATLQAFRDMGVVIEGPHHGRVTIHGVGLHGLKPAPGPIYLGNSGTSMRLL
SGLLAAQDFDSTLTGDASLSKRPMNRVANPLREMGAVIETAAEGRPPMTIRGGHKLKGLTYTMPMASAQVKSCLLLAGLY
AEGKTTVTEPAPTRDHTERMLRGFGYPVSVNGATASVESGGKLTATHIEVPGDISSSAFFLVAASIAEGSELVLEHVGIN
PTRTGVIDILRLMGADITLENQREVGGEPVADLRVRAAKLKGIEIPEALVPLAIDEFPVLFVAAACAEGRTVLTGAEELR
VKESDRIQVMADGLLALGVKCEPTPDGIIIDGGQIGGGEVHGHGDHRIAMAFSVASLRATAPIRIHDCANVATSFPNFLA
LCAQVGIRVAQEAQS

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=438, Percent_Identity=30.1369863013699, Blast_Score=132, Evalue=9e-32,
Organism=Saccharomyces cerevisiae, GI6320332, Length=420, Percent_Identity=29.0476190476191, Blast_Score=123, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 77955; Mature: 77955

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGRLVVVGLGLIGGSFAKGLRESGVCREVVGVDLDPQSRKLAVELGVVDRCEDDLVAAC
CCCCEEEEHHHHHCHHHHHHHHHCCCHHHHHCCCCCCCCCEEEEEECCHHCCCHHHHHHH
RGADVIQLAVPILAMEKVLARLAGMDLGQAILTDVGSAKGNVVRAATEAFGGMPARFVPG
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEHHHHHCCCCCCCCCC
HPIAGSEQSGVEASNSELFRRHKVILTPLEQTDPAALAVVDRLWRELGADVEHMQVERHD
CCCCCCCCCCCCCCCHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
EVLAATSHLPHLLAFGLVDSLAKRNENLEIFRYAAGGFRDFTRIAGSDPVMWHDIFLANR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHCCCCCEEEEHEEHHCH
EAVLRTLDTFRSDLDALRDAVDAGDGHQLLGVFTRARVAREHFSKILARRAYVDAMNSND
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LIFLAQPGGRLSGRIRVPGDKSISHRSIMLGSLAEGVTEVEGFLEGEDALATLQAFRDMG
EEEEECCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
VVIEGPHHGRVTIHGVGLHGLKPAPGPIYLGNSGTSMRLLSGLLAAQDFDSTLTGDASLS
CEEECCCCCEEEEEEECCCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCHHH
KRPMNRVANPLREMGAVIETAAEGRPPMTIRGGHKLKGLTYTMPMASAQVKSCLLLAGLY
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEECCCCHHHHHHHHHHHHHH
AEGKTTVTEPAPTRDHTERMLRGFGYPVSVNGATASVESGGKLTATHIEVPGDISSSAFF
CCCCEEECCCCCCHHHHHHHHHHCCCCEEECCCEEECCCCCEEEEEEEECCCCCCCCEEE
LVAASIAEGSELVLEHVGINPTRTGVIDILRLMGADITLENQREVGGEPVADLRVRAAKL
EEEEHHCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCEECCCHHCCCCCHHHHHHHHHHH
KGIEIPEALVPLAIDEFPVLFVAAACAEGRTVLTGAEELRVKESDRIQVMADGLLALGVK
CCCCCCHHHHHHHHCCHHHHHHHHHHCCCCEEEECHHHHCCCCCCCEEEEECCHHHCCCC
CEPTPDGIIIDGGQIGGGEVHGHGDHRIAMAFSVASLRATAPIRIHDCANVATSFPNFLA
CCCCCCCEEEECCEECCCEECCCCCCEEEEEEEHHHHHCCCCEEEECHHHHHHCCHHHHH
LCAQVGIRVAQEAQS
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MIGRLVVVGLGLIGGSFAKGLRESGVCREVVGVDLDPQSRKLAVELGVVDRCEDDLVAAC
CCCCEEEEHHHHHCHHHHHHHHHCCCHHHHHCCCCCCCCCEEEEEECCHHCCCHHHHHHH
RGADVIQLAVPILAMEKVLARLAGMDLGQAILTDVGSAKGNVVRAATEAFGGMPARFVPG
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEHHHHHCCCCCCCCCC
HPIAGSEQSGVEASNSELFRRHKVILTPLEQTDPAALAVVDRLWRELGADVEHMQVERHD
CCCCCCCCCCCCCCCHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
EVLAATSHLPHLLAFGLVDSLAKRNENLEIFRYAAGGFRDFTRIAGSDPVMWHDIFLANR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHCCCCCEEEEHEEHHCH
EAVLRTLDTFRSDLDALRDAVDAGDGHQLLGVFTRARVAREHFSKILARRAYVDAMNSND
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LIFLAQPGGRLSGRIRVPGDKSISHRSIMLGSLAEGVTEVEGFLEGEDALATLQAFRDMG
EEEEECCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
VVIEGPHHGRVTIHGVGLHGLKPAPGPIYLGNSGTSMRLLSGLLAAQDFDSTLTGDASLS
CEEECCCCCEEEEEEECCCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCHHH
KRPMNRVANPLREMGAVIETAAEGRPPMTIRGGHKLKGLTYTMPMASAQVKSCLLLAGLY
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEECCCCHHHHHHHHHHHHHH
AEGKTTVTEPAPTRDHTERMLRGFGYPVSVNGATASVESGGKLTATHIEVPGDISSSAFF
CCCCEEECCCCCCHHHHHHHHHHCCCCEEECCCEEECCCCCEEEEEEEECCCCCCCCEEE
LVAASIAEGSELVLEHVGINPTRTGVIDILRLMGADITLENQREVGGEPVADLRVRAAKL
EEEEHHCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCEECCCHHCCCCCHHHHHHHHHHH
KGIEIPEALVPLAIDEFPVLFVAAACAEGRTVLTGAEELRVKESDRIQVMADGLLALGVK
CCCCCCHHHHHHHHCCHHHHHHHHHHCCCCEEEECHHHHCCCCCCCEEEEECCHHHCCCC
CEPTPDGIIIDGGQIGGGEVHGHGDHRIAMAFSVASLRATAPIRIHDCANVATSFPNFLA
CCCCCCCEEEECCEECCCEECCCCCCEEEEEEEHHHHHCCCCEEEECHHHHHHCCHHHHH
LCAQVGIRVAQEAQS
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA