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The map label for this gene is fabF [H]

Identifier: 77460259

GI number: 77460259

Start: 4564535

End: 4565428

Strand: Reverse

Name: fabF [H]

Synonym: Pfl01_4038

Alternate gene names: 77460259

Gene position: 4565428-4564535 (Counterclockwise)

Preceding gene: 77460260

Following gene: 77460257

Centisome position: 70.91

GC content: 66.55

Gene sequence:

>894_bases
GTGCGCACCACCGACAGCCGTGGTCCGCGACGGTTGTCGCCGTTCACCATTCCCTCGTTTCTGGTCAATCTCGCCGCAGG
GCATGTCTCGATCCAGCACGGTCTCAAGGGCCCGCTCGGCGCTCCGGTCACCGCGTGTGCCGCCGGCGTGCAGGCGATCG
GTGACGCTGCGCGATTGATTCGTGCCGGTGAGGCCGACATCGCGGTGTGCGGCGGTGCGGAAGCCTGCATCGATCGCGTC
AGTCTTGCCGGTTTTGCGGCAGCGCGGGCTTTGTCCAGTGGCTACAACGACACCCCTGAGCGCGCCTCGCGCCCGTTCGA
CAGCGGACGTGACGGTTTCGTGATGGGCGAGGGCGCCGGTCTGCTGGTGATCGAGTCGCTGGAGCACGCGCTGGCGCGCG
GCGCACAGCCGTTGGTCGAACTGGTCGGCTACGGCACGAGCGCTGACGCCTATCACCTGACCGCCGGGCCGGAGGATGGT
AGCGGTGCCCGCCGGGCGATGGCATTGGCGCTGGCCCAGGCCGGTATCACGCCGGATCAGGTGCAGCATCTGAACGCCCA
TGCGACATCGACGCCTGTGGGCGACCTCGGTGAGCTGGCGGCGATCAAGTCGGTGTTTGGCGCGCAAAGCGCAATCGCCG
TGACCTCGACCAAATCCGCGACGGGGCATTTGCTGGGTGCGGCGGGGGGGCTGGAAGCGATCTTCACGCTGTTGGCGATC
CGCGATCAAATCGTTCCGCCGACCCTCAACCTGGAAAATCCAGATCCGGTGAGCGAAGGCGTGGATATCGTCCACGGTCA
GGCGCGGTCGATGCCGATCGAGTATGCGTTGTCCAACGGGTTCGGTTTCGGCGGGGTCAATGCCAGCGTGCTGTTCAAGC
GCTGGCAGGCTTAG

Upstream 100 bases:

>100_bases
TGAACAGGCCGGCTGGCACCCGACCGAATCCGGCGCTCAGGAACGCACCGCCACCATCATCGGCTCCGGTGTCGGCGGCT
TCGGCGCTATCGCCGATGCG

Downstream 100 bases:

>100_bases
TCTTCCGAGCGTTTGAGGTGTTCGCGGGTGACGTCCAGGATGCGTTGCGCCAACCCGGCATCCGCGACACTGCGTGACAG
CAGGAGCGCCCCGACCAGTG

Product: 3-oxoacyl-(acyl carrier protein) synthase

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MRTTDSRGPRRLSPFTIPSFLVNLAAGHVSIQHGLKGPLGAPVTACAAGVQAIGDAARLIRAGEADIAVCGGAEACIDRV
SLAGFAAARALSSGYNDTPERASRPFDSGRDGFVMGEGAGLLVIESLEHALARGAQPLVELVGYGTSADAYHLTAGPEDG
SGARRAMALALAQAGITPDQVQHLNAHATSTPVGDLGELAAIKSVFGAQSAIAVTSTKSATGHLLGAAGGLEAIFTLLAI
RDQIVPPTLNLENPDPVSEGVDIVHGQARSMPIEYALSNGFGFGGVNASVLFKRWQA

Sequences:

>Translated_297_residues
MRTTDSRGPRRLSPFTIPSFLVNLAAGHVSIQHGLKGPLGAPVTACAAGVQAIGDAARLIRAGEADIAVCGGAEACIDRV
SLAGFAAARALSSGYNDTPERASRPFDSGRDGFVMGEGAGLLVIESLEHALARGAQPLVELVGYGTSADAYHLTAGPEDG
SGARRAMALALAQAGITPDQVQHLNAHATSTPVGDLGELAAIKSVFGAQSAIAVTSTKSATGHLLGAAGGLEAIFTLLAI
RDQIVPPTLNLENPDPVSEGVDIVHGQARSMPIEYALSNGFGFGGVNASVLFKRWQA
>Mature_297_residues
MRTTDSRGPRRLSPFTIPSFLVNLAAGHVSIQHGLKGPLGAPVTACAAGVQAIGDAARLIRAGEADIAVCGGAEACIDRV
SLAGFAAARALSSGYNDTPERASRPFDSGRDGFVMGEGAGLLVIESLEHALARGAQPLVELVGYGTSADAYHLTAGPEDG
SGARRAMALALAQAGITPDQVQHLNAHATSTPVGDLGELAAIKSVFGAQSAIAVTSTKSATGHLLGAAGGLEAIFTLLAI
RDQIVPPTLNLENPDPVSEGVDIVHGQARSMPIEYALSNGFGFGGVNASVLFKRWQA

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthes

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=290, Percent_Identity=51.0344827586207, Blast_Score=272, Evalue=2e-73,
Organism=Homo sapiens, GI223972627, Length=146, Percent_Identity=50, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI41872631, Length=295, Percent_Identity=25.4237288135593, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI1787337, Length=289, Percent_Identity=55.0173010380623, Blast_Score=298, Evalue=4e-82,
Organism=Escherichia coli, GI1788663, Length=293, Percent_Identity=40.6143344709898, Blast_Score=204, Evalue=4e-54,
Organism=Caenorhabditis elegans, GI71983541, Length=291, Percent_Identity=42.6116838487972, Blast_Score=224, Evalue=3e-59,
Organism=Caenorhabditis elegans, GI71983535, Length=266, Percent_Identity=42.4812030075188, Blast_Score=197, Evalue=5e-51,
Organism=Caenorhabditis elegans, GI212642053, Length=296, Percent_Identity=29.7297297297297, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17550940, Length=258, Percent_Identity=31.0077519379845, Blast_Score=80, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6320904, Length=297, Percent_Identity=45.7912457912458, Blast_Score=256, Evalue=3e-69,
Organism=Drosophila melanogaster, GI24644341, Length=294, Percent_Identity=51.7006802721088, Blast_Score=292, Evalue=2e-79,
Organism=Drosophila melanogaster, GI221330659, Length=281, Percent_Identity=26.3345195729537, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI19920632, Length=281, Percent_Identity=26.3345195729537, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24581345, Length=280, Percent_Identity=23.5714285714286, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 30252; Mature: 30252

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTTDSRGPRRLSPFTIPSFLVNLAAGHVSIQHGLKGPLGAPVTACAAGVQAIGDAARLI
CCCCCCCCCCCCCCCCHHHHHHHHHHCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH
RAGEADIAVCGGAEACIDRVSLAGFAAARALSSGYNDTPERASRPFDSGRDGFVMGEGAG
HCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCEEEECCCC
LLVIESLEHALARGAQPLVELVGYGTSADAYHLTAGPEDGSGARRAMALALAQAGITPDQ
EEEHHHHHHHHHCCCHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCHHH
VQHLNAHATSTPVGDLGELAAIKSVFGAQSAIAVTSTKSATGHLLGAAGGLEAIFTLLAI
HHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCEEECCCCHHHHHHHHHH
RDQIVPPTLNLENPDPVSEGVDIVHGQARSMPIEYALSNGFGFGGVNASVLFKRWQA
HHHCCCCCCCCCCCCCHHHCCHHHCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MRTTDSRGPRRLSPFTIPSFLVNLAAGHVSIQHGLKGPLGAPVTACAAGVQAIGDAARLI
CCCCCCCCCCCCCCCCHHHHHHHHHHCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH
RAGEADIAVCGGAEACIDRVSLAGFAAARALSSGYNDTPERASRPFDSGRDGFVMGEGAG
HCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCEEEECCCC
LLVIESLEHALARGAQPLVELVGYGTSADAYHLTAGPEDGSGARRAMALALAQAGITPDQ
EEEHHHHHHHHHCCCHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCHHH
VQHLNAHATSTPVGDLGELAAIKSVFGAQSAIAVTSTKSATGHLLGAAGGLEAIFTLLAI
HHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCEEECCCCHHHHHHHHHH
RDQIVPPTLNLENPDPVSEGVDIVHGQARSMPIEYALSNGFGFGGVNASVLFKRWQA
HHHCCCCCCCCCCCCCHHHCCHHHCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10784042; 11481430 [H]