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The map label for this gene is kdpE [H]

Identifier: 77460250

GI number: 77460250

Start: 4552906

End: 4553631

Strand: Reverse

Name: kdpE [H]

Synonym: Pfl01_4029

Alternate gene names: 77460250

Gene position: 4553631-4552906 (Counterclockwise)

Preceding gene: 77460251

Following gene: 77460249

Centisome position: 70.73

GC content: 64.88

Gene sequence:

>726_bases
ATGAGCCAGACCGCGACCATTTTGGTCATCGATGACGAACCGCAGATCCGCAAGTTCCTGCGCATCAGCCTCGCTTCCCA
GGGCTACAAAGTGCTGGAGGCCGGCACCGGCGCCGAGGGCCTGGCCCAGGCGGCGCTGAACAAACCGGACCTGCTGGTGC
TCGACCTCGGCCTGCCGGACATGGACGGCCAGCAGGTACTGCGCGAGTTTCGCGAATGGGCCACGGCGCCGGTGCTGGTG
CTGTCCGTGCGCGCCAGCGAAGGGCAGAAAGTCCAGGCGCTGGATGGCGGCGCCAATGACTACGTGACCAAGCCGTTCGG
CATTCAGGAGTTTCTCGCCCGGGTGCGCGCGTTGCTGCGCCAGGCGCCAGCGGGGGAAGCGCAGCAGGCCGCGTTGAATT
TCGGCCCGCTGACCGTGGATCTGGCGTATCGGCGGGTGCTGCTCGACGGTGTCGAAGTCGGCCTGACTCGCAAGGAGTAC
GCGGTGCTGGCGCAACTGGCGCGGCATCCGGGGCGTGTGATCACCCAGCAGCAATTGCTCAAAGACATCTGGGGCCCGAC
TCACACCGAGGACAGCCACTACCTGCGGATCGTGGTCGGGCATCTGCGGCAGAAGCTGGCAGACGATCCGACCCGGCCCC
GGTTTATCGTGACCGAGGCGGGTGTGGGGTATCGGTTGTTGGATAATCAGGTTCCATCGACAATCGAAATATCCGATGGG
ATCTGA

Upstream 100 bases:

>100_bases
CACCTTGCACCTGCCGTTGCAGACGCAACCGGGGATGGACGATGAAGCCTGATCCACGCTGCGCTACTCTCTTGCCACTC
TTTTGTGTTGATGTGAATTC

Downstream 100 bases:

>100_bases
GTGCTATTTACCGGGTTACCGTTCATCGTGACTGTCAGTTCTGTCAGGTGCGATGCGTGAGTTGCCAGCTGTAAGTTCTT
CTAGCGAATGATCAGGGCCA

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MSQTATILVIDDEPQIRKFLRISLASQGYKVLEAGTGAEGLAQAALNKPDLLVLDLGLPDMDGQQVLREFREWATAPVLV
LSVRASEGQKVQALDGGANDYVTKPFGIQEFLARVRALLRQAPAGEAQQAALNFGPLTVDLAYRRVLLDGVEVGLTRKEY
AVLAQLARHPGRVITQQQLLKDIWGPTHTEDSHYLRIVVGHLRQKLADDPTRPRFIVTEAGVGYRLLDNQVPSTIEISDG
I

Sequences:

>Translated_241_residues
MSQTATILVIDDEPQIRKFLRISLASQGYKVLEAGTGAEGLAQAALNKPDLLVLDLGLPDMDGQQVLREFREWATAPVLV
LSVRASEGQKVQALDGGANDYVTKPFGIQEFLARVRALLRQAPAGEAQQAALNFGPLTVDLAYRRVLLDGVEVGLTRKEY
AVLAQLARHPGRVITQQQLLKDIWGPTHTEDSHYLRIVVGHLRQKLADDPTRPRFIVTEAGVGYRLLDNQVPSTIEISDG
I
>Mature_240_residues
SQTATILVIDDEPQIRKFLRISLASQGYKVLEAGTGAEGLAQAALNKPDLLVLDLGLPDMDGQQVLREFREWATAPVLVL
SVRASEGQKVQALDGGANDYVTKPFGIQEFLARVRALLRQAPAGEAQQAALNFGPLTVDLAYRRVLLDGVEVGLTRKEYA
VLAQLARHPGRVITQQQLLKDIWGPTHTEDSHYLRIVVGHLRQKLADDPTRPRFIVTEAGVGYRLLDNQVPSTIEISDGI

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=50.4504504504504, Blast_Score=228, Evalue=3e-61,
Organism=Escherichia coli, GI87082012, Length=221, Percent_Identity=35.7466063348416, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1787375, Length=220, Percent_Identity=34.5454545454545, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=33.4841628959276, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1789809, Length=232, Percent_Identity=30.6034482758621, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1790552, Length=226, Percent_Identity=34.070796460177, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1789402, Length=222, Percent_Identity=34.6846846846847, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1788394, Length=230, Percent_Identity=31.7391304347826, Blast_Score=111, Evalue=3e-26,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=29.7413793103448, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI1790860, Length=230, Percent_Identity=33.4782608695652, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1786599, Length=228, Percent_Identity=32.0175438596491, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=30.2631578947368, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI2367329, Length=224, Percent_Identity=30.3571428571429, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI145693140, Length=229, Percent_Identity=27.9475982532751, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1788550, Length=112, Percent_Identity=36.6071428571429, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1790299, Length=138, Percent_Identity=33.3333333333333, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26452; Mature: 26321

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQTATILVIDDEPQIRKFLRISLASQGYKVLEAGTGAEGLAQAALNKPDLLVLDLGLPD
CCCCEEEEEECCCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHCCCCCEEEEECCCCC
MDGQQVLREFREWATAPVLVLSVRASEGQKVQALDGGANDYVTKPFGIQEFLARVRALLR
CCHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHH
QAPAGEAQQAALNFGPLTVDLAYRRVLLDGVEVGLTRKEYAVLAQLARHPGRVITQQQLL
HCCCCCHHHHHHCCCCEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHH
KDIWGPTHTEDSHYLRIVVGHLRQKLADDPTRPRFIVTEAGVGYRLLDNQVPSTIEISDG
HHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEECCCCCCCEEEECCC
I
C
>Mature Secondary Structure 
SQTATILVIDDEPQIRKFLRISLASQGYKVLEAGTGAEGLAQAALNKPDLLVLDLGLPD
CCCEEEEEECCCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHCCCCCEEEEECCCCC
MDGQQVLREFREWATAPVLVLSVRASEGQKVQALDGGANDYVTKPFGIQEFLARVRALLR
CCHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHH
QAPAGEAQQAALNFGPLTVDLAYRRVLLDGVEVGLTRKEYAVLAQLARHPGRVITQQQLL
HCCCCCHHHHHHCCCCEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHH
KDIWGPTHTEDSHYLRIVVGHLRQKLADDPTRPRFIVTEAGVGYRLLDNQVPSTIEISDG
HHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEECCCCCCCEEEECCC
I
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]