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The map label for this gene is yafC [H]

Identifier: 77460216

GI number: 77460216

Start: 4524260

End: 4525216

Strand: Direct

Name: yafC [H]

Synonym: Pfl01_3995

Alternate gene names: 77460216

Gene position: 4524260-4525216 (Clockwise)

Preceding gene: 77460214

Following gene: 77460217

Centisome position: 70.27

GC content: 64.58

Gene sequence:

>957_bases
ATGAATCCCAATCAATTGACCGAACAACTCGGACTGTTTCTCGATGTGCTGGAGAGTGGCAGTTTTTCCGCTGCCTCGCG
CCGACATCCGCTGACACCATCCGCCGTTGCCCGGCGTATCGACAGTCTGGAAAGCGCTGTCGGCAGCCAGTTGTTTATCC
GCAGCACTCACGCGGTGCGCGCCACGCCGGCGGGTCTGGCGTTTGCCGAACGGGCGCGGCGCATCGTGGCGGAGTTGCAA
CTTGCCCGGGCTGAAGCGGTATCCCTGAGCAGTGCGCCGGAGGGTCTGATTCGGGTGGATGCGCCGGCGGCGTTCGGACG
GCGGCATCTGGCGCCGGTGATTGCCGATTTTCTGGTGTTGTATCCGGGGCTGGACGTACAACTGCATTTAATCGACAGCT
TCGTCGACATGGACGGTTCAAACCTGGGTAAAGTCGATCTGGTGTTGCGCGCCGGGCAAATGGCTGACACCCGGCTGGTG
GCCACCCCTCTGGCGAGCATGGTGCGCATTGCCTGCGCCAGCCCCGACTATCTCAAGCGCCGCGGCGTACCGAGCGAACC
CGCGCAATTGAGCGAGCATGACGGCCTCGATTGGGACGGCCTCGCCCCGCCCTTCGCCTGGCGCTTCGAACAGGATGGAC
AAATGCAATTGCACCGCCCGGCGCGGGTGCGCATGAGCGCCAACAACGCCGAGGCGCTGGTGTGCGGCGCGCTGGCGGGA
CTCGGGATCGCGCATCTGCCAACCTGGCTGGCCAGCGAATACCTGTTGCGTGGCGAATTGCTGCCGCTGTTCTGTGAAAA
CGGCCTGCCGAAACCGGAAAGCACCGGCATCTATGCACTACGGCTGGAGCAACAGGCCAGCTCCCGCAGCCGCCTGCTGC
TGGAGTACCTCAAGACCCGGTTCAGCCCCGTGCCGCCGTGGGATCTGGCCCTGCAACGGGAGCTGGGCCGGCACTGA

Upstream 100 bases:

>100_bases
CATACGTCAGGCAACTCATCCTACGCAGTCGGCGCTGGCACGGAAACGCACAGCAACGCACAATGGCTGTGCTAAATCCG
CATAGGCACTGGACTGATTC

Downstream 100 bases:

>100_bases
CCAATTCACCACCGGGGACAATTGTCTGGCGCATTAAAGATTCGAGCGCTAGATTCATCTGCATTACCGTTCAAGGCACC
GACATGACCACCGACCGTAG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MNPNQLTEQLGLFLDVLESGSFSAASRRHPLTPSAVARRIDSLESAVGSQLFIRSTHAVRATPAGLAFAERARRIVAELQ
LARAEAVSLSSAPEGLIRVDAPAAFGRRHLAPVIADFLVLYPGLDVQLHLIDSFVDMDGSNLGKVDLVLRAGQMADTRLV
ATPLASMVRIACASPDYLKRRGVPSEPAQLSEHDGLDWDGLAPPFAWRFEQDGQMQLHRPARVRMSANNAEALVCGALAG
LGIAHLPTWLASEYLLRGELLPLFCENGLPKPESTGIYALRLEQQASSRSRLLLEYLKTRFSPVPPWDLALQRELGRH

Sequences:

>Translated_318_residues
MNPNQLTEQLGLFLDVLESGSFSAASRRHPLTPSAVARRIDSLESAVGSQLFIRSTHAVRATPAGLAFAERARRIVAELQ
LARAEAVSLSSAPEGLIRVDAPAAFGRRHLAPVIADFLVLYPGLDVQLHLIDSFVDMDGSNLGKVDLVLRAGQMADTRLV
ATPLASMVRIACASPDYLKRRGVPSEPAQLSEHDGLDWDGLAPPFAWRFEQDGQMQLHRPARVRMSANNAEALVCGALAG
LGIAHLPTWLASEYLLRGELLPLFCENGLPKPESTGIYALRLEQQASSRSRLLLEYLKTRFSPVPPWDLALQRELGRH
>Mature_318_residues
MNPNQLTEQLGLFLDVLESGSFSAASRRHPLTPSAVARRIDSLESAVGSQLFIRSTHAVRATPAGLAFAERARRIVAELQ
LARAEAVSLSSAPEGLIRVDAPAAFGRRHLAPVIADFLVLYPGLDVQLHLIDSFVDMDGSNLGKVDLVLRAGQMADTRLV
ATPLASMVRIACASPDYLKRRGVPSEPAQLSEHDGLDWDGLAPPFAWRFEQDGQMQLHRPARVRMSANNAEALVCGALAG
LGIAHLPTWLASEYLLRGELLPLFCENGLPKPESTGIYALRLEQQASSRSRLLLEYLKTRFSPVPPWDLALQRELGRH

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=302, Percent_Identity=31.1258278145695, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI145693193, Length=259, Percent_Identity=31.6602316602317, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1789440, Length=298, Percent_Identity=29.5302013422819, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1789639, Length=289, Percent_Identity=29.4117647058824, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI87081978, Length=310, Percent_Identity=29.0322580645161, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1787128, Length=289, Percent_Identity=26.9896193771626, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787589, Length=244, Percent_Identity=27.8688524590164, Blast_Score=81, Evalue=8e-17,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34732; Mature: 34732

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPNQLTEQLGLFLDVLESGSFSAASRRHPLTPSAVARRIDSLESAVGSQLFIRSTHAVR
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCC
ATPAGLAFAERARRIVAELQLARAEAVSLSSAPEGLIRVDAPAAFGRRHLAPVIADFLVL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHH
YPGLDVQLHLIDSFVDMDGSNLGKVDLVLRAGQMADTRLVATPLASMVRIACASPDYLKR
CCCCCEEEEEHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHH
RGVPSEPAQLSEHDGLDWDGLAPPFAWRFEQDGQMQLHRPARVRMSANNAEALVCGALAG
CCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEECCCEEEEEECCCCCHHHHHHHHH
LGIAHLPTWLASEYLLRGELLPLFCENGLPKPESTGIYALRLEQQASSRSRLLLEYLKTR
CCHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHH
FSPVPPWDLALQRELGRH
CCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MNPNQLTEQLGLFLDVLESGSFSAASRRHPLTPSAVARRIDSLESAVGSQLFIRSTHAVR
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCC
ATPAGLAFAERARRIVAELQLARAEAVSLSSAPEGLIRVDAPAAFGRRHLAPVIADFLVL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHH
YPGLDVQLHLIDSFVDMDGSNLGKVDLVLRAGQMADTRLVATPLASMVRIACASPDYLKR
CCCCCEEEEEHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHH
RGVPSEPAQLSEHDGLDWDGLAPPFAWRFEQDGQMQLHRPARVRMSANNAEALVCGALAG
CCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEECCCEEEEEECCCCCHHHHHHHHH
LGIAHLPTWLASEYLLRGELLPLFCENGLPKPESTGIYALRLEQQASSRSRLLLEYLKTR
CCHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHH
FSPVPPWDLALQRELGRH
CCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]