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The map label for this gene is dgdR [H]

Identifier: 77460214

GI number: 77460214

Start: 4522518

End: 4523408

Strand: Direct

Name: dgdR [H]

Synonym: Pfl01_3993

Alternate gene names: 77460214

Gene position: 4522518-4523408 (Clockwise)

Preceding gene: 77460211

Following gene: 77460216

Centisome position: 70.24

GC content: 59.71

Gene sequence:

>891_bases
ATGTTTCTGATGGCATGCATCACGGAGATTCATCAATTGTCGGCGTACCCCAGTATCGATACCGATGTTCTGCGCACCTT
TGTCGCGATTGCCGATCAGGGCGGTTTTACCCGTGCCGGCGAAATGGTCAACCGCACCCAATCGGCGGTGAGCATGCAAA
TGAAGCGTCTGGAAGAGGACGTGTTGCAGCGCCAGTTGTTCGAGCGCGACGGACGTCAGGTGCGCCTGACCGCCGAAGGC
CAGGTGTTGCTTGGTTACGCGCGGCGCATCCTGAAATTGCACAGCGAAGTGTTCAACACCCTGCGCGAGCCGCACATGGT
CGGCACGGTGCGGATCGGCACGCCGGACGATTACGTGATGCGGTTTCTGCCGGGGATCCTGTCGCGCTTCGCCCAGTTCT
ATCCGCTGATCCAGATCGAAGTGCATTGCGAGTCGACCAAGCAATTGCTGCAACGCACGGACCTGGATCTGTCGATCGTC
ACCCGCGAGCCAGGCAACGAGATCGGCCAACTGCTGCGCAAGGAGCGTTTTGTCTGGGCCGAGGCGCAGAACTTCAGCGC
CCACGAGCAGACGCCGTTGCCACTGGCAATGTTCAACAGTGATTGCTTCTGTCGCCTGTGGGCCTGCAATGCGCTGGACG
CTATGGGCCGCGAATACCGGATCGCCTACAACAGCACCAGCCTGTCGGCATTGATGGCGGTGGTGAGCGCCGGCCTGGCG
ATCACCGCGCAGCTGGAAAGCCTGATTACCCCAGACATGCGGATTCTTGGAGATGCCGAAAATCTGCCGCTGCTGCCCGA
GGCCAGCATCATGCTGATCCGCAACCTCAACAATCCCTCGCCGATCACCGAATGCCTGGCCGAGCACATCGTCGAAGGCT
TCAAACTTTAA

Upstream 100 bases:

>100_bases
CACTCTTTCATCGCTCACATACAGTTTTTGACCTTTCATCGTGTTGCCCTCCTTTAGGGATGGCTCAAGTCTCGCGCCGG
CGCTACGATCAATCCAACGA

Downstream 100 bases:

>100_bases
ACGCGAGCATCACCGCGCACAGCACCAGGAACCCGCAGAACAGCCCACGCAGGAGTTTTTCCGGCATCGCGTGGGCCACT
TTCACGCCCCAACTGATGCT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: 2,2-dialkylglycine decarboxylase repressor [H]

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MFLMACITEIHQLSAYPSIDTDVLRTFVAIADQGGFTRAGEMVNRTQSAVSMQMKRLEEDVLQRQLFERDGRQVRLTAEG
QVLLGYARRILKLHSEVFNTLREPHMVGTVRIGTPDDYVMRFLPGILSRFAQFYPLIQIEVHCESTKQLLQRTDLDLSIV
TREPGNEIGQLLRKERFVWAEAQNFSAHEQTPLPLAMFNSDCFCRLWACNALDAMGREYRIAYNSTSLSALMAVVSAGLA
ITAQLESLITPDMRILGDAENLPLLPEASIMLIRNLNNPSPITECLAEHIVEGFKL

Sequences:

>Translated_296_residues
MFLMACITEIHQLSAYPSIDTDVLRTFVAIADQGGFTRAGEMVNRTQSAVSMQMKRLEEDVLQRQLFERDGRQVRLTAEG
QVLLGYARRILKLHSEVFNTLREPHMVGTVRIGTPDDYVMRFLPGILSRFAQFYPLIQIEVHCESTKQLLQRTDLDLSIV
TREPGNEIGQLLRKERFVWAEAQNFSAHEQTPLPLAMFNSDCFCRLWACNALDAMGREYRIAYNSTSLSALMAVVSAGLA
ITAQLESLITPDMRILGDAENLPLLPEASIMLIRNLNNPSPITECLAEHIVEGFKL
>Mature_296_residues
MFLMACITEIHQLSAYPSIDTDVLRTFVAIADQGGFTRAGEMVNRTQSAVSMQMKRLEEDVLQRQLFERDGRQVRLTAEG
QVLLGYARRILKLHSEVFNTLREPHMVGTVRIGTPDDYVMRFLPGILSRFAQFYPLIQIEVHCESTKQLLQRTDLDLSIV
TREPGNEIGQLLRKERFVWAEAQNFSAHEQTPLPLAMFNSDCFCRLWACNALDAMGREYRIAYNSTSLSALMAVVSAGLA
ITAQLESLITPDMRILGDAENLPLLPEASIMLIRNLNNPSPITECLAEHIVEGFKL

Specific function: Not Known, Does Not Seem To Act On The Proton Translocating NADH Dehydrogenase Genes (Nuoa-N) Which Are Part Of The Lrha Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788626, Length=258, Percent_Identity=34.4961240310078, Blast_Score=151, Evalue=4e-38,
Organism=Escherichia coli, GI157672245, Length=227, Percent_Identity=28.6343612334802, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI145693105, Length=143, Percent_Identity=31.4685314685315, Blast_Score=75, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33404; Mature: 33404

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLMACITEIHQLSAYPSIDTDVLRTFVAIADQGGFTRAGEMVNRTQSAVSMQMKRLEED
CHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VLQRQLFERDGRQVRLTAEGQVLLGYARRILKLHSEVFNTLREPHMVGTVRIGTPDDYVM
HHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHH
RFLPGILSRFAQFYPLIQIEVHCESTKQLLQRTDLDLSIVTREPGNEIGQLLRKERFVWA
HHHHHHHHHHHHHCCEEEEEEECHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHEE
EAQNFSAHEQTPLPLAMFNSDCFCRLWACNALDAMGREYRIAYNSTSLSALMAVVSAGLA
ECCCCCCCCCCCCCCEEECCCCEEEEEEHHHHHHCCCCEEEEECCHHHHHHHHHHHCCHH
ITAQLESLITPDMRILGDAENLPLLPEASIMLIRNLNNPSPITECLAEHIVEGFKL
HHHHHHHHCCCCHHEECCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFLMACITEIHQLSAYPSIDTDVLRTFVAIADQGGFTRAGEMVNRTQSAVSMQMKRLEED
CHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VLQRQLFERDGRQVRLTAEGQVLLGYARRILKLHSEVFNTLREPHMVGTVRIGTPDDYVM
HHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHH
RFLPGILSRFAQFYPLIQIEVHCESTKQLLQRTDLDLSIVTREPGNEIGQLLRKERFVWA
HHHHHHHHHHHHHCCEEEEEEECHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHEE
EAQNFSAHEQTPLPLAMFNSDCFCRLWACNALDAMGREYRIAYNSTSLSALMAVVSAGLA
ECCCCCCCCCCCCCCEEECCCCEEEEEEHHHHHHCCCCEEEEECCHHHHHHHHHHHCCHH
ITAQLESLITPDMRILGDAENLPLLPEASIMLIRNLNNPSPITECLAEHIVEGFKL
HHHHHHHHCCCCHHEECCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2180928 [H]