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The map label for this gene is yafC [C]

Identifier: 77460131

GI number: 77460131

Start: 4426861

End: 4427769

Strand: Direct

Name: yafC [C]

Synonym: Pfl01_3910

Alternate gene names: 77460131

Gene position: 4426861-4427769 (Clockwise)

Preceding gene: 77460129

Following gene: 77460136

Centisome position: 68.76

GC content: 61.17

Gene sequence:

>909_bases
ATGGACAAGCTCAACGCAATGGCCATCTTCGTCCGGGTGGTCGAACGCGGCAGTTTCTCCGCCGTTGCCCGGGAACTGCA
CACCACCCAGCCGACCATCAGCAAAGTGCTGCGCGCCCTTGAGAATGAATTGGGCGGCAAGCTGATTGCCCGCAGTACAC
GCAAGCTGTCACTGACCGATGAAGGTCAGCGGTACTACAACGAATGTCGAAATATCCTCGCCGCCGTGGACGCTGCCGAG
CACAGTTTCCAGTCCGGCAGGGAAACCGTCGCCGGACCTTTGCGGATCGGCTCCTCCGTCAGTTTCGGCCGCTTGCATAT
CGCTTCGCGGCTGGCGGAGTTTCTGCAGCGCTTTCCGCAGGTGCAGGTCGACCTGCAACTGAGCGATCAGAATCTGGATC
TGGTCAGCGAAGGCCTGGACGTCAGCCTGCGCATCGGCGAGCTGAACGACAGCGGCATGATCGCCCGACGCATCGGCACC
ACCCACCGGCTCACGGTGGCGACGCCCGATTACCTGCGACGCCACGGCCACCCACAATCACCTCAGGATCTTGCGCAGCA
CAACTGCCTGCAATTCAACCTGCTCAGCACTCAGAACCTGTGGACTTACGAGAAGGATGGCCAACACCACGACGTACGCA
TCCAGGGCAACGCCCAGAGCAACAACTCCGAAGCGATCCGCGAAATGGTCTTGGGAGGACTGGGGGTTTCGCTGTCACCG
GTCTGGCTGTTCAGCGAAGATTTGAAGGCGGGTCGAGTGATCGCCCTGTTGCAGGACTACCAGACCCGATCATTGCCGAT
TCACGCCGTGTCCCCGGCGAACCGTCGCCAGTCCGCCAGGGTCAACGCGTTTGTCGACTTCATGACCCAGGCGCTGGCTG
CAGCGCCCGAGCTTCAACCGATCAGATAG

Upstream 100 bases:

>100_bases
TGTGGGAGAAAGTGAAGCCATGTTCCCGCAGCAGCTCCATGCCGATAAGACGTCAAATGACTATAGTAAGCATGCCAAAT
CGGCATGAATGAGGCGCTTC

Downstream 100 bases:

>100_bases
CGGCAGTACGCGTGTTCAGCCATTCCAGTGCCGCGCCATCGAGCAGCGGACTCAGGCGCTCGCGCACTTCGGCGTGATAG
GCGTTGAACCATTGTTTCTC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MDKLNAMAIFVRVVERGSFSAVARELHTTQPTISKVLRALENELGGKLIARSTRKLSLTDEGQRYYNECRNILAAVDAAE
HSFQSGRETVAGPLRIGSSVSFGRLHIASRLAEFLQRFPQVQVDLQLSDQNLDLVSEGLDVSLRIGELNDSGMIARRIGT
THRLTVATPDYLRRHGHPQSPQDLAQHNCLQFNLLSTQNLWTYEKDGQHHDVRIQGNAQSNNSEAIREMVLGGLGVSLSP
VWLFSEDLKAGRVIALLQDYQTRSLPIHAVSPANRRQSARVNAFVDFMTQALAAAPELQPIR

Sequences:

>Translated_302_residues
MDKLNAMAIFVRVVERGSFSAVARELHTTQPTISKVLRALENELGGKLIARSTRKLSLTDEGQRYYNECRNILAAVDAAE
HSFQSGRETVAGPLRIGSSVSFGRLHIASRLAEFLQRFPQVQVDLQLSDQNLDLVSEGLDVSLRIGELNDSGMIARRIGT
THRLTVATPDYLRRHGHPQSPQDLAQHNCLQFNLLSTQNLWTYEKDGQHHDVRIQGNAQSNNSEAIREMVLGGLGVSLSP
VWLFSEDLKAGRVIALLQDYQTRSLPIHAVSPANRRQSARVNAFVDFMTQALAAAPELQPIR
>Mature_302_residues
MDKLNAMAIFVRVVERGSFSAVARELHTTQPTISKVLRALENELGGKLIARSTRKLSLTDEGQRYYNECRNILAAVDAAE
HSFQSGRETVAGPLRIGSSVSFGRLHIASRLAEFLQRFPQVQVDLQLSDQNLDLVSEGLDVSLRIGELNDSGMIARRIGT
THRLTVATPDYLRRHGHPQSPQDLAQHNCLQFNLLSTQNLWTYEKDGQHHDVRIQGNAQSNNSEAIREMVLGGLGVSLSP
VWLFSEDLKAGRVIALLQDYQTRSLPIHAVSPANRRQSARVNAFVDFMTQALAAAPELQPIR

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=292, Percent_Identity=34.2465753424658, Blast_Score=188, Evalue=5e-49,
Organism=Escherichia coli, GI145693193, Length=302, Percent_Identity=31.7880794701987, Blast_Score=164, Evalue=8e-42,
Organism=Escherichia coli, GI1789639, Length=289, Percent_Identity=30.4498269896194, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI87081978, Length=291, Percent_Identity=31.2714776632302, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1789440, Length=283, Percent_Identity=31.095406360424, Blast_Score=151, Evalue=4e-38,
Organism=Escherichia coli, GI1787128, Length=287, Percent_Identity=28.9198606271777, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1787589, Length=281, Percent_Identity=27.7580071174377, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1789173, Length=294, Percent_Identity=25.8503401360544, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1788706, Length=295, Percent_Identity=21.6949152542373, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI157672245, Length=242, Percent_Identity=28.099173553719, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787601, Length=147, Percent_Identity=30.6122448979592, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87082132, Length=297, Percent_Identity=23.2323232323232, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1790011, Length=319, Percent_Identity=23.5109717868339, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787879, Length=146, Percent_Identity=32.1917808219178, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786448, Length=193, Percent_Identity=27.4611398963731, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787806, Length=156, Percent_Identity=33.974358974359, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1790399, Length=264, Percent_Identity=25, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789204, Length=245, Percent_Identity=25.7142857142857, Blast_Score=61, Evalue=1e-10,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33567; Mature: 33567

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLNAMAIFVRVVERGSFSAVARELHTTQPTISKVLRALENELGGKLIARSTRKLSLTD
CCCHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEECCCCCEEECCC
EGQRYYNECRNILAAVDAAEHSFQSGRETVAGPLRIGSSVSFGRLHIASRLAEFLQRFPQ
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHCCC
VQVDLQLSDQNLDLVSEGLDVSLRIGELNDSGMIARRIGTTHRLTVATPDYLRRHGHPQS
EEEEEEECCCCCHHHHCCCCEEEEEECCCCCCCCHHHCCCCEEEEEECHHHHHHCCCCCC
PQDLAQHNCLQFNLLSTQNLWTYEKDGQHHDVRIQGNAQSNNSEAIREMVLGGLGVSLSP
HHHHHHCCCEEEEEECCCCCEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCE
VWLFSEDLKAGRVIALLQDYQTRSLPIHAVSPANRRQSARVNAFVDFMTQALAAAPELQP
EEEECCCCCCCCEEEEEHHCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
IR
CC
>Mature Secondary Structure
MDKLNAMAIFVRVVERGSFSAVARELHTTQPTISKVLRALENELGGKLIARSTRKLSLTD
CCCHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEECCCCCEEECCC
EGQRYYNECRNILAAVDAAEHSFQSGRETVAGPLRIGSSVSFGRLHIASRLAEFLQRFPQ
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHCCC
VQVDLQLSDQNLDLVSEGLDVSLRIGELNDSGMIARRIGTTHRLTVATPDYLRRHGHPQS
EEEEEEECCCCCHHHHCCCCEEEEEECCCCCCCCHHHCCCCEEEEEECHHHHHHCCCCCC
PQDLAQHNCLQFNLLSTQNLWTYEKDGQHHDVRIQGNAQSNNSEAIREMVLGGLGVSLSP
HHHHHHCCCEEEEEECCCCCEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCE
VWLFSEDLKAGRVIALLQDYQTRSLPIHAVSPANRRQSARVNAFVDFMTQALAAAPELQP
EEEECCCCCCCCEEEEEHHCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
IR
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]