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The map label for this gene is nahD [H]

Identifier: 77460129

GI number: 77460129

Start: 4425163

End: 4425753

Strand: Direct

Name: nahD [H]

Synonym: Pfl01_3908

Alternate gene names: 77460129

Gene position: 4425163-4425753 (Clockwise)

Preceding gene: 77460128

Following gene: 77460131

Centisome position: 68.73

GC content: 58.04

Gene sequence:

>591_bases
ATGAGCAAAAGCGTGGAGTTCTATTTCGATCTCGGCAGCCCCGCCACTTACCTGGCGTACACCCAACTGCCGAAAATCTG
CGCCGAGACCGGCAGCCAGTTGATCTACATTCCGATGTTGCTGGGCGGCGTCTTCAAAGCCACCGGCAACGCGTCGCCGG
CAATGATCCCGGCCAAGGGTCGTTACATGTTTCAGGACCTGGACCGCTACGCCAAACGCTACGGTGTACCCTTGAAATTC
AACCCGCATTTTCCGATCAATACCCTGATGTTGATGCGCGCGGTCACCGGCATTCAGCTGCGACATCCCGATCGCTTTCA
GCCGTTCATCGATTGCCTGTTCAAAGCGCTGTGGGTTGAAGGGAGCCCCCTCGATGAGCCGGCAGCGGTTGCCGCCGTGC
TGACCGAACATGGCTTCAATCCTGAAGAGGTACTGGCATTGACCAACGATGACGCAGTCAAGGCCATGCTCAAGGACAAC
ACCGAGACCGCAGTGAAGCGCGGCGTCTTCGGCGCGCCGAGCATGTTCATCGACAACCAGTTGTTCTTCGGTCAGGACCG
GCTCGACTTCGTGCTGGAAGCCCTTCGCTAA

Upstream 100 bases:

>100_bases
GCATAGCCAGCCACGGGACGCCTGGACGTTCGAGCTGGATCTGCGTCCGTGGAACGAACGCTGGTAATTCCCCCAATAAC
AAAAACAGAGTGCAGCGAAC

Downstream 100 bases:

>100_bases
ATCTCCACAACCAAACGCCCCTGAGCTGCTTTCGTTGCAAGCAGCTCATGGGCTTTTGCTGCGGTTTCCAGCGTGAACCG
ATGCGGATCGAGCAGCGGTC

Product: DSBA oxidoreductase

Products: NA

Alternate protein names: HCCA isomerase [H]

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MSKSVEFYFDLGSPATYLAYTQLPKICAETGSQLIYIPMLLGGVFKATGNASPAMIPAKGRYMFQDLDRYAKRYGVPLKF
NPHFPINTLMLMRAVTGIQLRHPDRFQPFIDCLFKALWVEGSPLDEPAAVAAVLTEHGFNPEEVLALTNDDAVKAMLKDN
TETAVKRGVFGAPSMFIDNQLFFGQDRLDFVLEALR

Sequences:

>Translated_196_residues
MSKSVEFYFDLGSPATYLAYTQLPKICAETGSQLIYIPMLLGGVFKATGNASPAMIPAKGRYMFQDLDRYAKRYGVPLKF
NPHFPINTLMLMRAVTGIQLRHPDRFQPFIDCLFKALWVEGSPLDEPAAVAAVLTEHGFNPEEVLALTNDDAVKAMLKDN
TETAVKRGVFGAPSMFIDNQLFFGQDRLDFVLEALR
>Mature_195_residues
SKSVEFYFDLGSPATYLAYTQLPKICAETGSQLIYIPMLLGGVFKATGNASPAMIPAKGRYMFQDLDRYAKRYGVPLKFN
PHFPINTLMLMRAVTGIQLRHPDRFQPFIDCLFKALWVEGSPLDEPAAVAAVLTEHGFNPEEVLALTNDDAVKAMLKDNT
ETAVKRGVFGAPSMFIDNQLFFGQDRLDFVLEALR

Specific function: Catalyzes the isomerization of 2-hydroxychromene-2- carboxylate (HCCA) to trans-O-hydroxybenzylidenepyruvate (THBPA). The reaction is reversible [H]

COG id: COG3917

COG function: function code Q; 2-hydroxychromene-2-carboxylate isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI7705704, Length=207, Percent_Identity=28.5024154589372, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI219842333, Length=204, Percent_Identity=27.4509803921569, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17538137, Length=204, Percent_Identity=29.4117647058824, Blast_Score=90, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17539520, Length=211, Percent_Identity=28.436018957346, Blast_Score=85, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001853
- InterPro:   IPR014440
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01323 DSBA [H]

EC number: NA

Molecular weight: Translated: 21876; Mature: 21744

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKSVEFYFDLGSPATYLAYTQLPKICAETGSQLIYIPMLLGGVFKATGNASPAMIPAKG
CCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCCCCCEECCCC
RYMFQDLDRYAKRYGVPLKFNPHFPINTLMLMRAVTGIQLRHPDRFQPFIDCLFKALWVE
CHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHCCEECCCCCCCHHHHHHHHHHHCC
GSPLDEPAAVAAVLTEHGFNPEEVLALTNDDAVKAMLKDNTETAVKRGVFGAPSMFIDNQ
CCCCCCHHHHHHHHHHCCCCHHHEEEECCCHHHHHHHHCCHHHHHHHCCCCCCCHHCCCE
LFFGQDRLDFVLEALR
EEECCHHHHHHHHHHC
>Mature Secondary Structure 
SKSVEFYFDLGSPATYLAYTQLPKICAETGSQLIYIPMLLGGVFKATGNASPAMIPAKG
CCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCCCCCEECCCC
RYMFQDLDRYAKRYGVPLKFNPHFPINTLMLMRAVTGIQLRHPDRFQPFIDCLFKALWVE
CHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHCCEECCCCCCCHHHHHHHHHHHCC
GSPLDEPAAVAAVLTEHGFNPEEVLALTNDDAVKAMLKDNTETAVKRGVFGAPSMFIDNQ
CCCCCCHHHHHHHHHHCCCCHHHEEEECCCHHHHHHHHCCHHHHHHHCCCCCCCHHCCCE
LFFGQDRLDFVLEALR
EEECCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002605; 1447127 [H]