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The map label for this gene is hdl IVa [H]

Identifier: 77460024

GI number: 77460024

Start: 4304853

End: 4305560

Strand: Reverse

Name: hdl IVa [H]

Synonym: Pfl01_3802

Alternate gene names: 77460024

Gene position: 4305560-4304853 (Counterclockwise)

Preceding gene: 77460026

Following gene: 77460023

Centisome position: 66.87

GC content: 63.56

Gene sequence:

>708_bases
ATGACCTTGATCAACACACCGCGCCCGCAATGGCTGACATTCGATTGCTACGGCACCTTGATTCAATGGGACGAAGGCCT
GCGCGCCGTGGCTGAGCGGATCCTCAGCGAGAAGGGCGAACACCGGGTCGACGCCGGGCGCCTGATCGAGGTTTACGACC
GCCACGAACATCGCCTGGAGCAGACGCCACCGCATCGCTCGTTTCGCGAACTCAGCACACTCGGCCTGCAACTGGCCCTG
GAAGAACTGGGGCTGGCGAGTGCCAGCCAGGACAGCCAGCGCCTGGCCGCCGCGATCCCGCAGATGCCGCCGTTCCCCGA
AGTCGTCGAGACCCTCGCGCAGCTCAAGGCCAAGGGTTTCAAGCTGTGCATCGTCTCCAACACCGATGACGACATCATCG
CCGGCAACGTCGCTCAATTGGGTGGCCACATAGACCGGGTGATCACCGCGCAGCAGGCCGGCGCCTACAAACCGGCGCCG
AGGCTGTTCGACTACGCTCATGAGCAATTGGGCGTCAGCCGCGATCAGGTGGTGCACATCTGCGCCAGCCCGATGCTCGA
CCACACGGCGGCCCGCGACATGCATTTTCGCTGCGTATGGATTGATCGAGGGACCGGTCGTCAGTTGCTGCCGGACTATC
GGCCCGACGCGATCCTCAACACGCTGGACGAAGTGCTGCCGCTGTTCGCATCCCTTGGCTGGTCATAA

Upstream 100 bases:

>100_bases
TCTCGATATTTGTTTGGCAACTGACGGTCGGCTATTTATTTAATTTCACACTATCACCCCGAGTTCATAAGCTGAAGCCC
TCACTTGCAGAGGAATTCCC

Downstream 100 bases:

>100_bases
AGGAGGTTCGCCATGGCCCATACCCTGACCGGCAGCGCCCGACCCGCGCGTTACACCTCGTTGAACCTCGACAGCGAAGC
CGTCATCACCGCTCGCAAAG

Product: haloacid dehalogenase, type II

Products: NA

Alternate protein names: 2-haloalkanoic acid dehalogenase IVA; Halocarboxylic acid halidohydrolase IVA; L-2-haloacid dehalogenase IVA [H]

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MTLINTPRPQWLTFDCYGTLIQWDEGLRAVAERILSEKGEHRVDAGRLIEVYDRHEHRLEQTPPHRSFRELSTLGLQLAL
EELGLASASQDSQRLAAAIPQMPPFPEVVETLAQLKAKGFKLCIVSNTDDDIIAGNVAQLGGHIDRVITAQQAGAYKPAP
RLFDYAHEQLGVSRDQVVHICASPMLDHTAARDMHFRCVWIDRGTGRQLLPDYRPDAILNTLDEVLPLFASLGWS

Sequences:

>Translated_235_residues
MTLINTPRPQWLTFDCYGTLIQWDEGLRAVAERILSEKGEHRVDAGRLIEVYDRHEHRLEQTPPHRSFRELSTLGLQLAL
EELGLASASQDSQRLAAAIPQMPPFPEVVETLAQLKAKGFKLCIVSNTDDDIIAGNVAQLGGHIDRVITAQQAGAYKPAP
RLFDYAHEQLGVSRDQVVHICASPMLDHTAARDMHFRCVWIDRGTGRQLLPDYRPDAILNTLDEVLPLFASLGWS
>Mature_234_residues
TLINTPRPQWLTFDCYGTLIQWDEGLRAVAERILSEKGEHRVDAGRLIEVYDRHEHRLEQTPPHRSFRELSTLGLQLALE
ELGLASASQDSQRLAAAIPQMPPFPEVVETLAQLKAKGFKLCIVSNTDDDIIAGNVAQLGGHIDRVITAQQAGAYKPAPR
LFDYAHEQLGVSRDQVVHICASPMLDHTAARDMHFRCVWIDRGTGRQLLPDYRPDAILNTLDEVLPLFASLGWS

Specific function: Catalyzes the hydrolytic dehalogenation of small (S)-2- haloalkanoic acids to yield the corresponding (R)-2- hydroxyalkanoic acids. Acts on acids of short chain lengths, C(2) to C(4), with inversion of configuration at C-3 [H]

COG id: COG1011

COG function: function code R; Predicted hydrolase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. S-2- haloalkanoic acid dehalogenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006388
- InterPro:   IPR006402
- InterPro:   IPR006328
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.8.1.2 [H]

Molecular weight: Translated: 26310; Mature: 26179

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLINTPRPQWLTFDCYGTLIQWDEGLRAVAERILSEKGEHRVDAGRLIEVYDRHEHRLE
CCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
QTPPHRSFRELSTLGLQLALEELGLASASQDSQRLAAAIPQMPPFPEVVETLAQLKAKGF
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCE
KLCIVSNTDDDIIAGNVAQLGGHIDRVITAQQAGAYKPAPRLFDYAHEQLGVSRDQVVHI
EEEEEECCCCCHHCCCHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHH
CASPMLDHTAARDMHFRCVWIDRGTGRQLLPDYRPDAILNTLDEVLPLFASLGWS
HHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TLINTPRPQWLTFDCYGTLIQWDEGLRAVAERILSEKGEHRVDAGRLIEVYDRHEHRLE
CCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
QTPPHRSFRELSTLGLQLALEELGLASASQDSQRLAAAIPQMPPFPEVVETLAQLKAKGF
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCE
KLCIVSNTDDDIIAGNVAQLGGHIDRVITAQQAGAYKPAPRLFDYAHEQLGVSRDQVVHI
EEEEEECCCCCHHCCCHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHH
CASPMLDHTAARDMHFRCVWIDRGTGRQLLPDYRPDAILNTLDEVLPLFASLGWS
HHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1376111 [H]