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The map label for this gene is sgaE [C]

Identifier: 77460023

GI number: 77460023

Start: 4304067

End: 4304840

Strand: Reverse

Name: sgaE [C]

Synonym: Pfl01_3801

Alternate gene names: 77460023

Gene position: 4304840-4304067 (Counterclockwise)

Preceding gene: 77460024

Following gene: 77460022

Centisome position: 66.86

GC content: 63.18

Gene sequence:

>774_bases
ATGGCCCATACCCTGACCGGCAGCGCCCGACCCGCGCGTTACACCTCGTTGAACCTCGACAGCGAAGCCGTCATCACCGC
TCGCAAAGAGCTGGCGGCGTGCTTTCAACTGGCGGCGCTGCACGGGTTGGAAGAGGGGATCTGCAATCACTTTTCGGCGA
TGTTGCCGGGGCATGCTGATCTGTTTCTGGTCAATCCGTACGGCTATGCGTTTTCCGAAGTCACGGCGCATAACCTGCTG
GTCTGCGACTTCGACGGCAACGTGGTGGACGGCGAGGGTCAGCCGGAAGCGACTGCTTTCTTTATTCATGCGCGGCTGCA
CCAGCGACTGCCCCGGGTGAAAGTCGCGTTCCATACGCACATGCCGAACGCGACGGCGTTGTGCCTGTTGGAGGGGCCGC
CGCTGTTGTGGCTGAGTCAGACCGCGCTGAAGTTCTACGGGCGCACGGCGGTGGACGAGCATTACAACGGGCTGGCGCTG
GACGCGCGTGAAGGCTACCGGATTGCCGGGGTCATTGGCGAGGCCGACATTCTGTTTCTGAAAAATCACGGGGTGATTGT
TGCGGCGCCGACCATTGCTGAAGCCTGGGACGATCTGTATTACCTGGAGCGTGCCGCGCAAGTGCAACTGTTGGCGATGG
CCACGCAACGGGTGTTGAAGCCGGTGCCGCACGCGGTGGCGCAGCGGGCGTACGAGCAGATGCGCGAGGGCGATCCGGAA
AGTGCGCGGGCGCATCTGCACAGTGCGATGCGGCGGTTGGCCCGTCAGGGCTGA

Upstream 100 bases:

>100_bases
TCAGTTGCTGCCGGACTATCGGCCCGACGCGATCCTCAACACGCTGGACGAAGTGCTGCCGCTGTTCGCATCCCTTGGCT
GGTCATAAAGGAGGTTCGCC

Downstream 100 bases:

>100_bases
TGCGGGCAAAAACGGGCAGGCAAAAATAATTTGCGTCGCAGGTCATCCAATTGCCCTGCGCGCCGATAGCAACTGGGTCG
GGATCGTCGCGAGGGCACTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MAHTLTGSARPARYTSLNLDSEAVITARKELAACFQLAALHGLEEGICNHFSAMLPGHADLFLVNPYGYAFSEVTAHNLL
VCDFDGNVVDGEGQPEATAFFIHARLHQRLPRVKVAFHTHMPNATALCLLEGPPLLWLSQTALKFYGRTAVDEHYNGLAL
DAREGYRIAGVIGEADILFLKNHGVIVAAPTIAEAWDDLYYLERAAQVQLLAMATQRVLKPVPHAVAQRAYEQMREGDPE
SARAHLHSAMRRLARQG

Sequences:

>Translated_257_residues
MAHTLTGSARPARYTSLNLDSEAVITARKELAACFQLAALHGLEEGICNHFSAMLPGHADLFLVNPYGYAFSEVTAHNLL
VCDFDGNVVDGEGQPEATAFFIHARLHQRLPRVKVAFHTHMPNATALCLLEGPPLLWLSQTALKFYGRTAVDEHYNGLAL
DAREGYRIAGVIGEADILFLKNHGVIVAAPTIAEAWDDLYYLERAAQVQLLAMATQRVLKPVPHAVAQRAYEQMREGDPE
SARAHLHSAMRRLARQG
>Mature_256_residues
AHTLTGSARPARYTSLNLDSEAVITARKELAACFQLAALHGLEEGICNHFSAMLPGHADLFLVNPYGYAFSEVTAHNLLV
CDFDGNVVDGEGQPEATAFFIHARLHQRLPRVKVAFHTHMPNATALCLLEGPPLLWLSQTALKFYGRTAVDEHYNGLALD
AREGYRIAGVIGEADILFLKNHGVIVAAPTIAEAWDDLYYLERAAQVQLLAMATQRVLKPVPHAVAQRAYEQMREGDPES
ARAHLHSAMRRLARQG

Specific function: Probable Pentulose-5-Phosphate-4-Epimerase. Probably Involved In A Metabolic Pathway With Sgah And Sgau. [C]

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family [H]

Homologues:

Organism=Homo sapiens, GI29826325, Length=195, Percent_Identity=30.2564102564103, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI29826323, Length=195, Percent_Identity=30.2564102564103, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI29826321, Length=195, Percent_Identity=30.2564102564103, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI29826319, Length=196, Percent_Identity=30.6122448979592, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI9951927, Length=230, Percent_Identity=26.9565217391304, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI62912453, Length=230, Percent_Identity=26.9565217391304, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI9943848, Length=230, Percent_Identity=26.9565217391304, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI297307160, Length=204, Percent_Identity=26.4705882352941, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI89276787, Length=192, Percent_Identity=26.0416666666667, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI9257190, Length=192, Percent_Identity=26.0416666666667, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI297307158, Length=192, Percent_Identity=26.5625, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI9257192, Length=192, Percent_Identity=26.5625, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115533218, Length=229, Percent_Identity=28.3842794759825, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI115533216, Length=210, Percent_Identity=29.0476190476191, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71989541, Length=182, Percent_Identity=29.6703296703297, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71989555, Length=181, Percent_Identity=29.2817679558011, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71989550, Length=181, Percent_Identity=29.2817679558011, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71989544, Length=181, Percent_Identity=29.2817679558011, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71989560, Length=181, Percent_Identity=29.2817679558011, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI281363755, Length=214, Percent_Identity=28.9719626168224, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281363751, Length=214, Percent_Identity=28.9719626168224, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24655690, Length=214, Percent_Identity=28.9719626168224, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24655685, Length=214, Percent_Identity=28.9719626168224, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281363761, Length=215, Percent_Identity=28.8372093023256, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281363759, Length=215, Percent_Identity=28.8372093023256, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281363753, Length=215, Percent_Identity=28.8372093023256, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281363763, Length=214, Percent_Identity=29.4392523364486, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI281363757, Length=214, Percent_Identity=29.4392523364486, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI17136738, Length=214, Percent_Identity=29.4392523364486, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: 5.1.-.- [C]

Molecular weight: Translated: 28274; Mature: 28142

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHTLTGSARPARYTSLNLDSEAVITARKELAACFQLAALHGLEEGICNHFSAMLPGHAD
CCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LFLVNPYGYAFSEVTAHNLLVCDFDGNVVDGEGQPEATAFFIHARLHQRLPRVKVAFHTH
EEEECCCCCHHHHHHHCEEEEECCCCCEECCCCCCCHHHEEHHHHHHHCCCCEEEEEEEC
MPNATALCLLEGPPLLWLSQTALKFYGRTAVDEHYNGLALDAREGYRIAGVIGEADILFL
CCCCEEEEEECCCCEEEHHHHHHHHHCCHHHHHCCCCEEEECCCCEEEEEEECCCEEEEE
KNHGVIVAAPTIAEAWDDLYYLERAAQVQLLAMATQRVLKPVPHAVAQRAYEQMREGDPE
ECCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCH
SARAHLHSAMRRLARQG
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AHTLTGSARPARYTSLNLDSEAVITARKELAACFQLAALHGLEEGICNHFSAMLPGHAD
CCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LFLVNPYGYAFSEVTAHNLLVCDFDGNVVDGEGQPEATAFFIHARLHQRLPRVKVAFHTH
EEEECCCCCHHHHHHHCEEEEECCCCCEECCCCCCCHHHEEHHHHHHHCCCCEEEEEEEC
MPNATALCLLEGPPLLWLSQTALKFYGRTAVDEHYNGLALDAREGYRIAGVIGEADILFL
CCCCEEEEEECCCCEEEHHHHHHHHHCCHHHHHCCCCEEEECCCCEEEEEEECCCEEEEE
KNHGVIVAAPTIAEAWDDLYYLERAAQVQLLAMATQRVLKPVPHAVAQRAYEQMREGDPE
ECCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCH
SARAHLHSAMRRLARQG
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]