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The map label for this gene is cph2 [H]

Identifier: 77460022

GI number: 77460022

Start: 4302307

End: 4303968

Strand: Reverse

Name: cph2 [H]

Synonym: Pfl01_3800

Alternate gene names: 77460022

Gene position: 4303968-4302307 (Counterclockwise)

Preceding gene: 77460023

Following gene: 77460017

Centisome position: 66.85

GC content: 62.21

Gene sequence:

>1662_bases
TTGGTTGCCCCACACAACCCGGTGGGCTACGCTCACAAAAAACAAGGGTTTCGGGCTTTTGCCCCTGTCGTACCTGCCCA
GGACACGCTTTTGCCTATCCCCATTCACGATCCGCATCAGGCCCCCGGCGGCACTCTCAAGCGTTTGCCCCTGCGCAAGG
CGGCGGTGTTGTTCATCGTTGCCGTGTGTCTGTGCCTGTCCGGTCTGCTGTATTTGCAGATCGAACAGTCGCGGCGCCAG
GATCTGGCCAACGCGCAGGTGTCGTCGGCCAACCTGACCCGGGCGATGGCGCAGCAGGCTGAAGACACGTTTCTGGCGGC
GGATCTGGTGATGACCAGCCTGGTCGACTGGGTTCAGGAAGATGGCTACGGTGCGGCGCAGAAGCCGCGATTGCAGCGAA
CCTTCGCGCGGCGAGTGCAACAACTCGAGCAGTTGCACGGCATGTTCCTGTTCGACCGCGAAGGGCAGTGGGTGATTACC
TCGTTCCCGGATCTGCCGCGCGGCAATGGCGTGGCCGATCGCGAGTACTTCAAGTTTCACCAGCAGAACGTGTCCGGTGT
GGCGCACATCGGCCCGGCGATCCGCAGCCGCGAGAACGGCGAGTGGATCATCCCGATCTCGAAACGGGTCAACGACCGCG
CCGGCAATTTCCAGGGCGTGTTGCTGGCCGGGATCAAGATGTCGTACTTCGACAAGTTCTTCAAAAGCTTCAGCCTGGAC
GACAACGGCACGATGTTTCTCGGCATGACTGACGGCACGTTGCTCGCCCGTCGGCCGTTCGACGAGTCTCTGATCGGCAC
CTCGCTGGCCAAGGGCGAGATCTATCAGAAGCTGCTGCCCAACGCCTCCGCCGGCACCGCGATGATCGATTCGGTGGTCG
ACGGTGTGACGCGTCTTTATGGTTACCGGCAGCTGGAAAGCTACCCGTTGGTGGTCGCGGCGTCTTCGTCCCGGGACACG
ATTCTCCAGGGCTGGTATGACCGGGCGTTTCAGTCCAGCGTGATCGTGGCGTTGGTGATGCTCGGCGTGGCGCTGTTCGG
CTGGGTGTTCATTCATCAGGTGCGCGATGGCGAGCGGATCGAAAAAAACCTGCGCAAGGCCCAGCAGGCGCTGGAGCAGA
TCGCCACCCACGACAGCCTGACCGGGCTGGCCAACCGGCGTCTGTTCGAGCGTTCGCTGGAGGTAGAGTTTGCCCGCGGT
GCGCGGCAGTCGAGCCCGGTCAGCCTGATCATGCTCGATATCGATTTTTTCAAACGCTACAACGATGCCTACGGCCACGT
GGCTGGCGACCATTGCCTGACGCAGGTCGCGCAGGTGGTGAAAAACTGCTGCCAGCGCAAGTCCGATCTGGCGGTGCGCT
ATGGCGGTGAAGAGTTCGCGGTGCTGCTGCCGGACACCGACATCAACGGCGCACTGGCAATTGCCGGGCAGATCCGCCGC
AGCGTGATGGACAAACACATCACCCACAGCGGTTCGCCCACCGGGTATCTCACGGTGAGCCTGGGTTGCTATGCGTTTAT
TCCGACCGGCAACGACAGCCCGGAACTGTTCATTCAACGCGCGGATGCGGCGCTGTATCAGGCCAAGAACGCCGGCCGCA
ACCGCGCGGCCGTGCTGTCAATGGACGTTGGCGTTGGCGAACTGATGCGTTCGGATCGCTGA

Upstream 100 bases:

>100_bases
GATGCGGGCAAAAACGGGCAGGCAAAAATAATTTGCGTCGCAGGTCATCCAATTGCCCTGCGCGCCGATAGCAACTGGGT
CGGGATCGTCGCGAGGGCAC

Downstream 100 bases:

>100_bases
CAAAATCGAATCGGTTCAGACACAGGCCATGGCCTTCACCATGACCTGCTCTTGTTCGTTCAGCCGCCCGTGCCACCGCC
GGCACCGCCCGTGCCGCCAC

Product: diguanylate cyclase

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 553; Mature: 553

Protein sequence:

>553_residues
MVAPHNPVGYAHKKQGFRAFAPVVPAQDTLLPIPIHDPHQAPGGTLKRLPLRKAAVLFIVAVCLCLSGLLYLQIEQSRRQ
DLANAQVSSANLTRAMAQQAEDTFLAADLVMTSLVDWVQEDGYGAAQKPRLQRTFARRVQQLEQLHGMFLFDREGQWVIT
SFPDLPRGNGVADREYFKFHQQNVSGVAHIGPAIRSRENGEWIIPISKRVNDRAGNFQGVLLAGIKMSYFDKFFKSFSLD
DNGTMFLGMTDGTLLARRPFDESLIGTSLAKGEIYQKLLPNASAGTAMIDSVVDGVTRLYGYRQLESYPLVVAASSSRDT
ILQGWYDRAFQSSVIVALVMLGVALFGWVFIHQVRDGERIEKNLRKAQQALEQIATHDSLTGLANRRLFERSLEVEFARG
ARQSSPVSLIMLDIDFFKRYNDAYGHVAGDHCLTQVAQVVKNCCQRKSDLAVRYGGEEFAVLLPDTDINGALAIAGQIRR
SVMDKHITHSGSPTGYLTVSLGCYAFIPTGNDSPELFIQRADAALYQAKNAGRNRAAVLSMDVGVGELMRSDR

Sequences:

>Translated_553_residues
MVAPHNPVGYAHKKQGFRAFAPVVPAQDTLLPIPIHDPHQAPGGTLKRLPLRKAAVLFIVAVCLCLSGLLYLQIEQSRRQ
DLANAQVSSANLTRAMAQQAEDTFLAADLVMTSLVDWVQEDGYGAAQKPRLQRTFARRVQQLEQLHGMFLFDREGQWVIT
SFPDLPRGNGVADREYFKFHQQNVSGVAHIGPAIRSRENGEWIIPISKRVNDRAGNFQGVLLAGIKMSYFDKFFKSFSLD
DNGTMFLGMTDGTLLARRPFDESLIGTSLAKGEIYQKLLPNASAGTAMIDSVVDGVTRLYGYRQLESYPLVVAASSSRDT
ILQGWYDRAFQSSVIVALVMLGVALFGWVFIHQVRDGERIEKNLRKAQQALEQIATHDSLTGLANRRLFERSLEVEFARG
ARQSSPVSLIMLDIDFFKRYNDAYGHVAGDHCLTQVAQVVKNCCQRKSDLAVRYGGEEFAVLLPDTDINGALAIAGQIRR
SVMDKHITHSGSPTGYLTVSLGCYAFIPTGNDSPELFIQRADAALYQAKNAGRNRAAVLSMDVGVGELMRSDR
>Mature_553_residues
MVAPHNPVGYAHKKQGFRAFAPVVPAQDTLLPIPIHDPHQAPGGTLKRLPLRKAAVLFIVAVCLCLSGLLYLQIEQSRRQ
DLANAQVSSANLTRAMAQQAEDTFLAADLVMTSLVDWVQEDGYGAAQKPRLQRTFARRVQQLEQLHGMFLFDREGQWVIT
SFPDLPRGNGVADREYFKFHQQNVSGVAHIGPAIRSRENGEWIIPISKRVNDRAGNFQGVLLAGIKMSYFDKFFKSFSLD
DNGTMFLGMTDGTLLARRPFDESLIGTSLAKGEIYQKLLPNASAGTAMIDSVVDGVTRLYGYRQLESYPLVVAASSSRDT
ILQGWYDRAFQSSVIVALVMLGVALFGWVFIHQVRDGERIEKNLRKAQQALEQIATHDSLTGLANRRLFERSLEVEFARG
ARQSSPVSLIMLDIDFFKRYNDAYGHVAGDHCLTQVAQVVKNCCQRKSDLAVRYGGEEFAVLLPDTDINGALAIAGQIRR
SVMDKHITHSGSPTGYLTVSLGCYAFIPTGNDSPELFIQRADAALYQAKNAGRNRAAVLSMDVGVGELMRSDR

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG3706

COG function: function code T; Response regulator containing a CheY-like receiver domain and a GGDEF domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI87081881, Length=186, Percent_Identity=40.8602150537634, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI145693134, Length=193, Percent_Identity=33.6787564766839, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI87082007, Length=204, Percent_Identity=36.7647058823529, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1786584, Length=194, Percent_Identity=31.9587628865979, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1788381, Length=174, Percent_Identity=36.2068965517241, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1787262, Length=196, Percent_Identity=35.2040816326531, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1787541, Length=181, Percent_Identity=34.2541436464088, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI1787802, Length=169, Percent_Identity=33.7278106508876, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787816, Length=165, Percent_Identity=34.5454545454545, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI87081974, Length=192, Percent_Identity=30.7291666666667, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788085, Length=178, Percent_Identity=29.7752808988764, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI87081977, Length=223, Percent_Identity=29.5964125560538, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788956, Length=178, Percent_Identity=32.5842696629214, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 61155; Mature: 61155

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAPHNPVGYAHKKQGFRAFAPVVPAQDTLLPIPIHDPHQAPGGTLKRLPLRKAAVLFIV
CCCCCCCCCCCHHHCCCEECCCCCCCCCCEEECCCCCCCCCCCCCHHHCCHHHHHHHHHH
AVCLCLSGLLYLQIEQSRRQDLANAQVSSANLTRAMAQQAEDTFLAADLVMTSLVDWVQE
HHHHHHCCCEEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DGYGAAQKPRLQRTFARRVQQLEQLHGMFLFDREGQWVITSFPDLPRGNGVADREYFKFH
CCCCCCCCCHHHHHHHHHHHHHHHHCCEEEECCCCCEEEECCCCCCCCCCCCCHHHHHHH
QQNVSGVAHIGPAIRSRENGEWIIPISKRVNDRAGNFQGVLLAGIKMSYFDKFFKSFSLD
HHCCCCHHHHCHHHHCCCCCCEEEECHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCC
DNGTMFLGMTDGTLLARRPFDESLIGTSLAKGEIYQKLLPNASAGTAMIDSVVDGVTRLY
CCCEEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
GYRQLESYPLVVAASSSRDTILQGWYDRAFQSSVIVALVMLGVALFGWVFIHQVRDGERI
HHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
EKNLRKAQQALEQIATHDSLTGLANRRLFERSLEVEFARGARQSSPVSLIMLDIDFFKRY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHHH
NDAYGHVAGDHCLTQVAQVVKNCCQRKSDLAVRYGGEEFAVLLPDTDINGALAIAGQIRR
CHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEECCCCCCCHHHHHHHHHH
SVMDKHITHSGSPTGYLTVSLGCYAFIPTGNDSPELFIQRADAALYQAKNAGRNRAAVLS
HHHHHHHCCCCCCCEEEEEEECEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEE
MDVGVGELMRSDR
ECCCHHHHHHCCC
>Mature Secondary Structure
MVAPHNPVGYAHKKQGFRAFAPVVPAQDTLLPIPIHDPHQAPGGTLKRLPLRKAAVLFIV
CCCCCCCCCCCHHHCCCEECCCCCCCCCCEEECCCCCCCCCCCCCHHHCCHHHHHHHHHH
AVCLCLSGLLYLQIEQSRRQDLANAQVSSANLTRAMAQQAEDTFLAADLVMTSLVDWVQE
HHHHHHCCCEEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DGYGAAQKPRLQRTFARRVQQLEQLHGMFLFDREGQWVITSFPDLPRGNGVADREYFKFH
CCCCCCCCCHHHHHHHHHHHHHHHHCCEEEECCCCCEEEECCCCCCCCCCCCCHHHHHHH
QQNVSGVAHIGPAIRSRENGEWIIPISKRVNDRAGNFQGVLLAGIKMSYFDKFFKSFSLD
HHCCCCHHHHCHHHHCCCCCCEEEECHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCC
DNGTMFLGMTDGTLLARRPFDESLIGTSLAKGEIYQKLLPNASAGTAMIDSVVDGVTRLY
CCCEEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
GYRQLESYPLVVAASSSRDTILQGWYDRAFQSSVIVALVMLGVALFGWVFIHQVRDGERI
HHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
EKNLRKAQQALEQIATHDSLTGLANRRLFERSLEVEFARGARQSSPVSLIMLDIDFFKRY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHHH
NDAYGHVAGDHCLTQVAQVVKNCCQRKSDLAVRYGGEEFAVLLPDTDINGALAIAGQIRR
CHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEECCCCCCCHHHHHHHHHH
SVMDKHITHSGSPTGYLTVSLGCYAFIPTGNDSPELFIQRADAALYQAKNAGRNRAAVLS
HHHHHHHCCCCCCCEEEEEEECEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEE
MDVGVGELMRSDR
ECCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]