Click here to switch to the map view.

The map label for this gene is adh [H]

Identifier: 77459981

GI number: 77459981

Start: 4257472

End: 4258428

Strand: Reverse

Name: adh [H]

Synonym: Pfl01_3759

Alternate gene names: 77459981

Gene position: 4258428-4257472 (Counterclockwise)

Preceding gene: 77459982

Following gene: 77459978

Centisome position: 66.14

GC content: 64.89

Gene sequence:

>957_bases
ATGAAAGCACTGCAATTCGATAAAACCGGCGACCTGTCGTCCCTGCGCTTCGTCGAGGTGCCGACGCCGGTGCCGGGCGC
TGACGAGGTGCTGGTGCAGATCAAGGCTGCAGGCCTCAATCCCAGCGACGTGAAGAACGTACTCGGGCGTTTTCCGTACA
CCACGCTGCCGCGTATTCCCGGTCGTGACTTTGCCGGTGTGGTGGTCGAAGGGCCGCAGGCGTTGATCGGTCAGGAAGTC
TGGGGCACCGGGCGTGAGCTGGGTTTTTTCGCCGATGGCTCCCACGCGCAGTTCGTCAAACTGCCGGCCAAGGGCGTGGC
GCATAAACCTTCGCGTTTGAGTTTCACTCAGGCCGCCAGCCTCGGGGTGCCTTACACCACGGCGTGGGATGCGCTCGAGC
GCAGTCTGGTCAGTGCGCAAACCCGTCTGCTGGTCATCGGCGGCGGGGCGGTGGCGACGGCGGCGCTGGCGCTGGCCAAA
GTGCGCGGCGCGCAGTTGCTGGCGGCGGCGCGGCGGACGGAGCAAGTCAAGGATCTGCAGGCGCAGGGTTATCAGACGAT
TCAGCTGGACAAGCCCGAGGAGCTGGGGGCGCAGGTCGATGCGGTGTATCGCGGCGGTGCCGATGTGATCTTCGACACCA
CCGGTTTCTGGCTGCCGGCCTCGGTCGCGGCATTGGCGACCTTCGGACGGATCGCGATCATCGCCGCACCGGTTGACGGG
CATGTGCAACTGCCGGCGCTGGCCCTGTATCGCAAGGGCGGTTCGGTGGTCGGCATCAACTCGTTGCTGTATGGCGTTGA
AGCCTGCGCGGCGATGCTGGATCAGTTTGGCCGGTTCTTCGACGAAGACCTGCTGCCACTGCCGCAAGGGTTGGTGGAAG
CGCCGCTGGCCGAAGGGCTGGCGCGGTATGCCGATGTGAATCAGGGCAGTGGCGACAAAGTGATTCTTGTCCCCTGA

Upstream 100 bases:

>100_bases
CTGGGCATGCTGGCGGGCGAGCAGTTGTGGCCGATGGGCCGGCAACTGGTCAGTGGCTGGCTGTCCTGAATCCTGTCTTT
TTCCTTTGGTGGAGATTTCC

Downstream 100 bases:

>100_bases
CAGTCTCTGTTTTTCATGACATCACAAAACTGTGGGAGCGAATTCGCTCCCACGGTTTTTTGGGTCTCAGGATTGCGGGA
CGCCGTTCTCCCACGCCGAC

Product: zinc-containing alcohol dehydrogenase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MKALQFDKTGDLSSLRFVEVPTPVPGADEVLVQIKAAGLNPSDVKNVLGRFPYTTLPRIPGRDFAGVVVEGPQALIGQEV
WGTGRELGFFADGSHAQFVKLPAKGVAHKPSRLSFTQAASLGVPYTTAWDALERSLVSAQTRLLVIGGGAVATAALALAK
VRGAQLLAAARRTEQVKDLQAQGYQTIQLDKPEELGAQVDAVYRGGADVIFDTTGFWLPASVAALATFGRIAIIAAPVDG
HVQLPALALYRKGGSVVGINSLLYGVEACAAMLDQFGRFFDEDLLPLPQGLVEAPLAEGLARYADVNQGSGDKVILVP

Sequences:

>Translated_318_residues
MKALQFDKTGDLSSLRFVEVPTPVPGADEVLVQIKAAGLNPSDVKNVLGRFPYTTLPRIPGRDFAGVVVEGPQALIGQEV
WGTGRELGFFADGSHAQFVKLPAKGVAHKPSRLSFTQAASLGVPYTTAWDALERSLVSAQTRLLVIGGGAVATAALALAK
VRGAQLLAAARRTEQVKDLQAQGYQTIQLDKPEELGAQVDAVYRGGADVIFDTTGFWLPASVAALATFGRIAIIAAPVDG
HVQLPALALYRKGGSVVGINSLLYGVEACAAMLDQFGRFFDEDLLPLPQGLVEAPLAEGLARYADVNQGSGDKVILVP
>Mature_318_residues
MKALQFDKTGDLSSLRFVEVPTPVPGADEVLVQIKAAGLNPSDVKNVLGRFPYTTLPRIPGRDFAGVVVEGPQALIGQEV
WGTGRELGFFADGSHAQFVKLPAKGVAHKPSRLSFTQAASLGVPYTTAWDALERSLVSAQTRLLVIGGGAVATAALALAK
VRGAQLLAAARRTEQVKDLQAQGYQTIQLDKPEELGAQVDAVYRGGADVIFDTTGFWLPASVAALATFGRIAIIAAPVDG
HVQLPALALYRKGGSVVGINSLLYGVEACAAMLDQFGRFFDEDLLPLPQGLVEAPLAEGLARYADVNQGSGDKVILVP

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=337, Percent_Identity=27.299703264095, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI22538444, Length=337, Percent_Identity=27.299703264095, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI194239674, Length=270, Percent_Identity=25.1851851851852, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI13236495, Length=270, Percent_Identity=25.1851851851852, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17507255, Length=286, Percent_Identity=29.3706293706294, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI71987554, Length=214, Percent_Identity=32.2429906542056, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 33456; Mature: 33456

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALQFDKTGDLSSLRFVEVPTPVPGADEVLVQIKAAGLNPSDVKNVLGRFPYTTLPRIP
CCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCCCC
GRDFAGVVVEGPQALIGQEVWGTGRELGFFADGSHAQFVKLPAKGVAHKPSRLSFTQAAS
CCCCCCEEEECCHHHHHHHHHCCCCCEEEEECCCCCEEEECCCCCCCCCCCCCCHHHHHH
LGVPYTTAWDALERSLVSAQTRLLVIGGGAVATAALALAKVRGAQLLAAARRTEQVKDLQ
CCCCCHHHHHHHHHHHHHHCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQGYQTIQLDKPEELGAQVDAVYRGGADVIFDTTGFWLPASVAALATFGRIAIIAAPVDG
HCCCEEEECCCCHHHCCCEEHHCCCCCCEEEECCCCCHHHHHHHHHHCCCEEEEEECCCC
HVQLPALALYRKGGSVVGINSLLYGVEACAAMLDQFGRFFDEDLLPLPQGLVEAPLAEGL
CEECCHHEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
ARYADVNQGSGDKVILVP
HHHHCCCCCCCCEEEEEC
>Mature Secondary Structure
MKALQFDKTGDLSSLRFVEVPTPVPGADEVLVQIKAAGLNPSDVKNVLGRFPYTTLPRIP
CCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCCCC
GRDFAGVVVEGPQALIGQEVWGTGRELGFFADGSHAQFVKLPAKGVAHKPSRLSFTQAAS
CCCCCCEEEECCHHHHHHHHHCCCCCEEEEECCCCCEEEECCCCCCCCCCCCCCHHHHHH
LGVPYTTAWDALERSLVSAQTRLLVIGGGAVATAALALAKVRGAQLLAAARRTEQVKDLQ
CCCCCHHHHHHHHHHHHHHCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQGYQTIQLDKPEELGAQVDAVYRGGADVIFDTTGFWLPASVAALATFGRIAIIAAPVDG
HCCCEEEECCCCHHHCCCEEHHCCCCCCEEEECCCCCHHHHHHHHHHCCCEEEEEECCCC
HVQLPALALYRKGGSVVGINSLLYGVEACAAMLDQFGRFFDEDLLPLPQGLVEAPLAEGL
CEECCHHEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
ARYADVNQGSGDKVILVP
HHHHCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572479 [H]