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The map label for this gene is entA [H]

Identifier: 77459692

GI number: 77459692

Start: 3955828

End: 3956571

Strand: Direct

Name: entA [H]

Synonym: Pfl01_3470

Alternate gene names: 77459692

Gene position: 3955828-3956571 (Clockwise)

Preceding gene: 77459689

Following gene: 77459694

Centisome position: 61.44

GC content: 62.77

Gene sequence:

>744_bases
ATGGATCATGTTTTTCAGGGCAAGCTTGCCGTCATCACCGGTGCCAGTTCGGGCATAGGCCTGGCCGCTACCGAGCGTCT
GCTCGATCAAGGCGCGCGCGTATTGGCCATGTCGCGAAAGCTCGGCGCACTGGCCGAACTGCTTGAGCGGTATCCGCAGC
AACTGGTGTGGCACTCCGGCGATGTCGCTCAAGCCGCTGACCTTGCCGCTTTGGCCGAGCAAGCTGCACGCATCGGTCCG
GTAAGTTTCGTGGTGCCCAACGCCGGTATCGCAGAACTGGCCGACGGGCTCGACAGCTCGGCATTCGGTCGCCAATGGGC
AGTAAACGGCGCCGGCGCCCTGAACACCTTGGCCGCCCTGCGCCCGCACCTTGCAGACAAGGCGTCAGTGGTGTTCATCG
GTACTTTTCTGGCCCGAATCAGTTTCGCGGGATTGGCCGCCTACATCGCGTCAAAAGCGGCGTTGATCGCCCATGCCCGA
ACCCTTGCAGTCGAGCTGGCACCCCACGGTGTGCGCATCAATTGCGTTTCCCCCGGCCCGACCGCAACGCCGATCTGGTC
GACATTGGGCCTGAGTGACGAAGCGCTCGGCGACGTGGCCCAAGGCGTCAACAAACGACTGCTGGGCGGACAATTCCTAG
AACCTGCGGCAGTGGCCGACGTCATTCTGTTCCAGCTGGGCAATGGCGCACGCGGCGTCATCGGTCAGGACTGGGTAGTC
GACAGCGGATACACCTTGAGCTAA

Upstream 100 bases:

>100_bases
ACCCTGCGCAGCCCTTGATATTAAAGGCTGTCCGGCATGGCCCGAAAATTGACTGGTCTCCCGTAGCCATTTGGCTGAAG
ACCAAAAACGGGAGTCGAAC

Downstream 100 bases:

>100_bases
CGCGCATGCACCGATCCGGGCGTGGAATCAGCCAACTGGCGACCTGACGAATCCCGCCCGGCTTCGGGCAAAACCAGCCC
CCAGCGCGATGACAATTCTC

Product: Short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MDHVFQGKLAVITGASSGIGLAATERLLDQGARVLAMSRKLGALAELLERYPQQLVWHSGDVAQAADLAALAEQAARIGP
VSFVVPNAGIAELADGLDSSAFGRQWAVNGAGALNTLAALRPHLADKASVVFIGTFLARISFAGLAAYIASKAALIAHAR
TLAVELAPHGVRINCVSPGPTATPIWSTLGLSDEALGDVAQGVNKRLLGGQFLEPAAVADVILFQLGNGARGVIGQDWVV
DSGYTLS

Sequences:

>Translated_247_residues
MDHVFQGKLAVITGASSGIGLAATERLLDQGARVLAMSRKLGALAELLERYPQQLVWHSGDVAQAADLAALAEQAARIGP
VSFVVPNAGIAELADGLDSSAFGRQWAVNGAGALNTLAALRPHLADKASVVFIGTFLARISFAGLAAYIASKAALIAHAR
TLAVELAPHGVRINCVSPGPTATPIWSTLGLSDEALGDVAQGVNKRLLGGQFLEPAAVADVILFQLGNGARGVIGQDWVV
DSGYTLS
>Mature_247_residues
MDHVFQGKLAVITGASSGIGLAATERLLDQGARVLAMSRKLGALAELLERYPQQLVWHSGDVAQAADLAALAEQAARIGP
VSFVVPNAGIAELADGLDSSAFGRQWAVNGAGALNTLAALRPHLADKASVVFIGTFLARISFAGLAAYIASKAALIAHAR
TLAVELAPHGVRINCVSPGPTATPIWSTLGLSDEALGDVAQGVNKRLLGGQFLEPAAVADVILFQLGNGARGVIGQDWVV
DSGYTLS

Specific function: Siderophore biosynthesis; enterobactin biosynthesis. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI5031737, Length=190, Percent_Identity=31.5789473684211, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI33667109, Length=190, Percent_Identity=31.5789473684211, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI32483357, Length=246, Percent_Identity=28.0487804878049, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI7705925, Length=252, Percent_Identity=26.5873015873016, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI40254992, Length=247, Percent_Identity=30.7692307692308, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI15277342, Length=241, Percent_Identity=30.7053941908714, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI59889578, Length=226, Percent_Identity=27.8761061946903, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI126723750, Length=252, Percent_Identity=25, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1786812, Length=253, Percent_Identity=33.9920948616601, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI87082100, Length=256, Percent_Identity=27.34375, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787335, Length=251, Percent_Identity=28.6852589641434, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI2367365, Length=182, Percent_Identity=30.7692307692308, Blast_Score=67, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=267, Percent_Identity=29.2134831460674, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17560150, Length=260, Percent_Identity=29.6153846153846, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17561402, Length=199, Percent_Identity=29.6482412060301, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17560332, Length=271, Percent_Identity=30.6273062730627, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562906, Length=264, Percent_Identity=29.1666666666667, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=262, Percent_Identity=29.3893129770992, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17544670, Length=266, Percent_Identity=26.6917293233083, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17562910, Length=261, Percent_Identity=27.2030651340996, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=271, Percent_Identity=29.8892988929889, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=262, Percent_Identity=29.3893129770992, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17562990, Length=260, Percent_Identity=29.2307692307692, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI72000259, Length=261, Percent_Identity=27.2030651340996, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=272, Percent_Identity=29.7794117647059, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25147288, Length=256, Percent_Identity=26.5625, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI115534694, Length=254, Percent_Identity=29.5275590551181, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17565030, Length=276, Percent_Identity=29.3478260869565, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=272, Percent_Identity=28.3088235294118, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71994604, Length=251, Percent_Identity=27.8884462151394, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=267, Percent_Identity=25.8426966292135, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=265, Percent_Identity=26.7924528301887, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=29.0836653386454, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17551412, Length=269, Percent_Identity=25.6505576208178, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322067, Length=202, Percent_Identity=28.7128712871287, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322226, Length=186, Percent_Identity=29.0322580645161, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=29.9595141700405, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI23397609, Length=248, Percent_Identity=31.8548387096774, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI21357041, Length=203, Percent_Identity=32.512315270936, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21355319, Length=253, Percent_Identity=30.0395256916996, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24644339, Length=198, Percent_Identity=32.3232323232323, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24639444, Length=232, Percent_Identity=29.7413793103448, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28571526, Length=201, Percent_Identity=29.3532338308458, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21358495, Length=194, Percent_Identity=30.4123711340206, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR003560
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.3.1.28 [H]

Molecular weight: Translated: 25394; Mature: 25394

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDHVFQGKLAVITGASSGIGLAATERLLDQGARVLAMSRKLGALAELLERYPQQLVWHSG
CCCCCCCCEEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DVAQAADLAALAEQAARIGPVSFVVPNAGIAELADGLDSSAFGRQWAVNGAGALNTLAAL
CHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHCCCCCCCCCCEEECCCCCHHHHHHHH
RPHLADKASVVFIGTFLARISFAGLAAYIASKAALIAHARTLAVELAPHGVRINCVSPGP
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEEECCCC
TATPIWSTLGLSDEALGDVAQGVNKRLLGGQFLEPAAVADVILFQLGNGARGVIGQDWVV
CCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEE
DSGYTLS
CCCCCCC
>Mature Secondary Structure
MDHVFQGKLAVITGASSGIGLAATERLLDQGARVLAMSRKLGALAELLERYPQQLVWHSG
CCCCCCCCEEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DVAQAADLAALAEQAARIGPVSFVVPNAGIAELADGLDSSAFGRQWAVNGAGALNTLAAL
CHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHCCCCCCCCCCEEECCCCCHHHHHHHH
RPHLADKASVVFIGTFLARISFAGLAAYIASKAALIAHARTLAVELAPHGVRINCVSPGP
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEEECCCC
TATPIWSTLGLSDEALGDVAQGVNKRLLGGQFLEPAAVADVILFQLGNGARGVIGQDWVV
CCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEE
DSGYTLS
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2521622; 2521621; 9278503 [H]