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The map label for this gene is iorA [H]

Identifier: 77459648

GI number: 77459648

Start: 3907532

End: 3907996

Strand: Reverse

Name: iorA [H]

Synonym: Pfl01_3426

Alternate gene names: 77459648

Gene position: 3907996-3907532 (Counterclockwise)

Preceding gene: 77459658

Following gene: 77459647

Centisome position: 60.7

GC content: 63.01

Gene sequence:

>465_bases
ATGATTGCATTCACGGTTAACGGCGAACGACGCGAGCTGGATGAGGCGTCCCCCTCCATGCCCTTGTTATGGGTGTTGCG
TGATCAGTTGAAACTCACCGGCACCAAGTTCGGTTGCGGCATGGGCCTGTGCGGTGCCTGCACCGTGCACCTGAACGGCG
TCGCGGTACGTTCCTGCCAGTTGCCGCTGGCCGCCGTCGCGGGCCACAGCATCACCACCATCGAGGGTTTGTCACCCAGC
GAAAGCCATCCGCTGCAACTGGCCTGGGTCGCCGAAGATGTGCCGCAATGCGGCTACTGTCAATCCGGGCAGATCATGTC
GGCAGCCGCGCTGCTCAACACCGGCGCACCGGTCAACGACGACTCGATCCGCAACGCGATGTCCGGGAATATCTGCCGCT
GCGGCACGTACGGGCGCATCAACAAAGCGATCAAACGGGCGGCGAATGCGCCGAAGGAGGCGTGA

Upstream 100 bases:

>100_bases
ACCGGTTGGCAGAAATCGTCGCTGGCCGCGCGTTGCCGGGGGTTCCAATAATCGGTCACCAGGCCCGCACAAAGACGGGC
CGCTCTTTTGGAGCCTGACA

Downstream 100 bases:

>100_bases
TGAGCCTCATCGACGGCACCCTTCAAGAACCCTCGCGCCGGGTGTTTCTCAAACAGGCGGTGACAGTGGCGTCCGGTCTG
GCGATTGCGCTGTACCTGCC

Product: ferredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MIAFTVNGERRELDEASPSMPLLWVLRDQLKLTGTKFGCGMGLCGACTVHLNGVAVRSCQLPLAAVAGHSITTIEGLSPS
ESHPLQLAWVAEDVPQCGYCQSGQIMSAAALLNTGAPVNDDSIRNAMSGNICRCGTYGRINKAIKRAANAPKEA

Sequences:

>Translated_154_residues
MIAFTVNGERRELDEASPSMPLLWVLRDQLKLTGTKFGCGMGLCGACTVHLNGVAVRSCQLPLAAVAGHSITTIEGLSPS
ESHPLQLAWVAEDVPQCGYCQSGQIMSAAALLNTGAPVNDDSIRNAMSGNICRCGTYGRINKAIKRAANAPKEA
>Mature_154_residues
MIAFTVNGERRELDEASPSMPLLWVLRDQLKLTGTKFGCGMGLCGACTVHLNGVAVRSCQLPLAAVAGHSITTIEGLSPS
ESHPLQLAWVAEDVPQCGYCQSGQIMSAAALLNTGAPVNDDSIRNAMSGNICRCGTYGRINKAIKRAANAPKEA

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=159, Percent_Identity=34.5911949685535, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1786480, Length=168, Percent_Identity=45.8333333333333, Blast_Score=117, Evalue=3e-28,
Organism=Escherichia coli, GI1789232, Length=147, Percent_Identity=38.0952380952381, Blast_Score=82, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17540638, Length=158, Percent_Identity=36.7088607594937, Blast_Score=103, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17539860, Length=154, Percent_Identity=36.3636363636364, Blast_Score=92, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI32566215, Length=154, Percent_Identity=35.7142857142857, Blast_Score=90, Evalue=5e-19,
Organism=Drosophila melanogaster, GI17737937, Length=157, Percent_Identity=34.3949044585987, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24647193, Length=159, Percent_Identity=35.8490566037736, Blast_Score=77, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24647201, Length=154, Percent_Identity=34.4155844155844, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24647195, Length=162, Percent_Identity=34.5679012345679, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24647197, Length=162, Percent_Identity=34.5679012345679, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24647199, Length=154, Percent_Identity=34.4155844155844, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 16200; Mature: 16200

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
8.4 %Cys+Met (Translated Protein)
5.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
8.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAFTVNGERRELDEASPSMPLLWVLRDQLKLTGTKFGCGMGLCGACTVHLNGVAVRSCQ
CEEEEECCCHHHHHHCCCCCCEEEEEHHHHHCCCCCCCCCCCCCEEEEEEECCEEEEECC
LPLAAVAGHSITTIEGLSPSESHPLQLAWVAEDVPQCGYCQSGQIMSAAALLNTGAPVND
CCHHHHCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCH
DSIRNAMSGNICRCGTYGRINKAIKRAANAPKEA
HHHHHHHCCCEEECCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MIAFTVNGERRELDEASPSMPLLWVLRDQLKLTGTKFGCGMGLCGACTVHLNGVAVRSCQ
CEEEEECCCHHHHHHCCCCCCEEEEEHHHHHCCCCCCCCCCCCCEEEEEEECCEEEEECC
LPLAAVAGHSITTIEGLSPSESHPLQLAWVAEDVPQCGYCQSGQIMSAAALLNTGAPVND
CCHHHHCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCH
DSIRNAMSGNICRCGTYGRINKAIKRAANAPKEA
HHHHHHHCCCEEECCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]