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The map label for this gene is cobM [H]

Identifier: 77459325

GI number: 77459325

Start: 3555300

End: 3556046

Strand: Direct

Name: cobM [H]

Synonym: Pfl01_3103

Alternate gene names: 77459325

Gene position: 3555300-3556046 (Clockwise)

Preceding gene: 77459324

Following gene: 77459329

Centisome position: 55.22

GC content: 61.58

Gene sequence:

>747_bases
ATGACCGTTTACTTCATCGGCGCCGGCCCCGGCGACCCGGAATTGATCACTGTCAAAGGCCAGCGGCTGATCCGCCGTTG
TCCGGTGATCATCTACGCAGGTTCGCTGGTGCCGACGGCAGTGCTGGAAGGTCATTGCGCTGAAACGGTGGTCAACAGCG
CCGAACTGCACCTGGAACAGATCATCGACCTGATCAAGACCGCCCACGCCAAGGGCCAGGATGTGGCGCGGGTACATTCC
GGGGATCCGAGTCTGTATGGCGCCATTGGTGAGCAGATTCGTTATCTGCGTGAGCTGGATATTCCGTTCGAGATCATTCC
CGGTGTGACCGCCACCGCCGCGTGCGCCGCGCTGCTGGGCGCCGAACTGACCCTGCCGGACATCTCGCAAAGCGTGATCC
TGACCCGTTATGCGGACAAGACTGCAATGCCTGCCGGCGAAGAGCTCGACAACCTGGCGCAGCACGGGGCGACCATGGCG
ATTCATCTGGGGGTCAATCATCTGGAGAAGATCGTCGCCGAGCTGCTGCCGCATTACGGCGCGGATTGCCCGATCGCGGT
GATTCATAGGGCGACATGGCCGGATCAGGACTGGGTGACGGGGACGCTGGAAGATATTGCCGAGAAGGTGGCGGCGAAGG
GCTTTCGGCGTACGGCGTTGATTCTGGTCGGGCGGGTGTTGGGCAGCGATCATTTCAGCGAGTCTTCGCTGTATCGCGCC
GGGCATGCGCATTTGTACCGGCCATAA

Upstream 100 bases:

>100_bases
GCGGCGTAAATTCCCGATAATCCCCGCTTTCGATCATGAGCATTCTTCATCTGAAGGGCTGGTGAAGCACCGCCCTGCCC
CTTTTCTACAGGATCCAACG

Downstream 100 bases:

>100_bases
AAAAACGGCGCTCACGGGGCGCCGTTTTTCATGCCGCAGCGAACACCTTAGTAGTAGGCGTTTTCTTTCTGCGTGTGGTC
GGTCACGTCGCGCACGCCCT

Product: precorrin-4 C11-methyltransferase

Products: NA

Alternate protein names: Precorrin-3 methylase [H]

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MTVYFIGAGPGDPELITVKGQRLIRRCPVIIYAGSLVPTAVLEGHCAETVVNSAELHLEQIIDLIKTAHAKGQDVARVHS
GDPSLYGAIGEQIRYLRELDIPFEIIPGVTATAACAALLGAELTLPDISQSVILTRYADKTAMPAGEELDNLAQHGATMA
IHLGVNHLEKIVAELLPHYGADCPIAVIHRATWPDQDWVTGTLEDIAEKVAAKGFRRTALILVGRVLGSDHFSESSLYRA
GHAHLYRP

Sequences:

>Translated_248_residues
MTVYFIGAGPGDPELITVKGQRLIRRCPVIIYAGSLVPTAVLEGHCAETVVNSAELHLEQIIDLIKTAHAKGQDVARVHS
GDPSLYGAIGEQIRYLRELDIPFEIIPGVTATAACAALLGAELTLPDISQSVILTRYADKTAMPAGEELDNLAQHGATMA
IHLGVNHLEKIVAELLPHYGADCPIAVIHRATWPDQDWVTGTLEDIAEKVAAKGFRRTALILVGRVLGSDHFSESSLYRA
GHAHLYRP
>Mature_247_residues
TVYFIGAGPGDPELITVKGQRLIRRCPVIIYAGSLVPTAVLEGHCAETVVNSAELHLEQIIDLIKTAHAKGQDVARVHSG
DPSLYGAIGEQIRYLRELDIPFEIIPGVTATAACAALLGAELTLPDISQSVILTRYADKTAMPAGEELDNLAQHGATMAI
HLGVNHLEKIVAELLPHYGADCPIAVIHRATWPDQDWVTGTLEDIAEKVAAKGFRRTALILVGRVLGSDHFSESSLYRAG
HAHLYRP

Specific function: Catalyzes the methylation of C-11 in precorrin-4 to form precorrin-5 [H]

COG id: COG2875

COG function: function code H; Precorrin-4 methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789768, Length=236, Percent_Identity=33.8983050847458, Blast_Score=108, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6322922, Length=236, Percent_Identity=25.8474576271186, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR006362
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.133 [H]

Molecular weight: Translated: 26733; Mature: 26602

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS00839 SUMT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVYFIGAGPGDPELITVKGQRLIRRCPVIIYAGSLVPTAVLEGHCAETVVNSAELHLEQ
CEEEEEECCCCCCCEEEECHHHHHHHCCEEEEECCHHHHHHHHCHHHHHHHHHHHHHHHH
IIDLIKTAHAKGQDVARVHSGDPSLYGAIGEQIRYLRELDIPFEIIPGVTATAACAALLG
HHHHHHHHCCCCCCHHEEECCCCHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHC
AELTLPDISQSVILTRYADKTAMPAGEELDNLAQHGATMAIHLGVNHLEKIVAELLPHYG
CCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHCC
ADCPIAVIHRATWPDQDWVTGTLEDIAEKVAAKGFRRTALILVGRVLGSDHFSESSLYRA
CCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHC
GHAHLYRP
CCCCCCCC
>Mature Secondary Structure 
TVYFIGAGPGDPELITVKGQRLIRRCPVIIYAGSLVPTAVLEGHCAETVVNSAELHLEQ
EEEEEECCCCCCCEEEECHHHHHHHCCEEEEECCHHHHHHHHCHHHHHHHHHHHHHHHH
IIDLIKTAHAKGQDVARVHSGDPSLYGAIGEQIRYLRELDIPFEIIPGVTATAACAALLG
HHHHHHHHCCCCCCHHEEECCCCHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHC
AELTLPDISQSVILTRYADKTAMPAGEELDNLAQHGATMAIHLGVNHLEKIVAELLPHYG
CCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHCC
ADCPIAVIHRATWPDQDWVTGTLEDIAEKVAAKGFRRTALILVGRVLGSDHFSESSLYRA
CCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHC
GHAHLYRP
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]