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The map label for this gene is caiD [C]

Identifier: 77459107

GI number: 77459107

Start: 3323358

End: 3324170

Strand: Reverse

Name: caiD [C]

Synonym: Pfl01_2882

Alternate gene names: 77459107

Gene position: 3324170-3323358 (Counterclockwise)

Preceding gene: 77459108

Following gene: 77459106

Centisome position: 51.63

GC content: 59.53

Gene sequence:

>813_bases
ATGACTCAATACACCGCCTTCAGCGTCGAACTGGCCGACAACATCGCCCATGTGCAGATCAATCGTCCGGAAAAGATCAA
CTCGATGAACGCCGCGTTCTGGAGCGAAATCGTCGAGGTGTTCCAGTGGATCGACGACACCGACGAAGTGCGGGTGGTGG
TGCTCAGCGGTGCCGGTAAACATTTCTCCTCGGGCATCGACCTGATGATGCTGGCCGGTGTGGCCAATGAGCTGGGCAAG
GACGTGGGCCGCAATGCGCGCCTGCTGCGCAAAAAGATCCTGACCCTGCAAGCCTCGTTCAATGCGGTCGACAATTGCCG
TAAACCGGTACTCGCGGCGATCCAGGGTTATTGCCTGGGCGGCGCTATCGACCTGATCGCCGCCTGCGACATGCGCTACG
CCGCCGAAGACGCGCAATTCTCGATCAAGGAAATCGACATCGGCATGGCGGCTGACGTCGGCACCTTGCAACGGTTGCCA
CGGATCATCGGTGACGGCATGCTGCGTGAACTGGCTTACACCGGTCGCACCTTTGGCGCCGAAGAAGCGCGCAGCATCGG
CCTGGTCAATCGCGTCTACAGCGACAAGGACGGCTTGATCGAAGGCGTGATGGACATTGCCCGGGACATCGCCGGCAAGT
CGCCGATCGCGGTCACCGGCACCAAGGAAATGATCAGCTACATGCGCGACCATCGCATTGACGACGGTCTCGAGTACGTT
GCCACCTGGAACGCCGCCATGCTGCAATCCAACGATTTGCGCGTGGCCATGGCCGCCCATATGAGCAAACAGAAACCCGA
ATTTCTGGATTGA

Upstream 100 bases:

>100_bases
GCGGTGAAGAACGGCTAGAGTCCCGCATTTGGCCGAACCGCCGTGCTGATGCCTTGTTATAGTTCGGGCCTCATTTTCAG
CCCGGTAAAGGATTTCTGCC

Downstream 100 bases:

>100_bases
GAAACCATGACATCTCGCTGGACCACTGCAGTACTGGACACCGATCAACCCGGCGGCTGGGCCGTGGCGCGCAGCCCCGA
GGGTTTCCTGTTCGATGACA

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MTQYTAFSVELADNIAHVQINRPEKINSMNAAFWSEIVEVFQWIDDTDEVRVVVLSGAGKHFSSGIDLMMLAGVANELGK
DVGRNARLLRKKILTLQASFNAVDNCRKPVLAAIQGYCLGGAIDLIAACDMRYAAEDAQFSIKEIDIGMAADVGTLQRLP
RIIGDGMLRELAYTGRTFGAEEARSIGLVNRVYSDKDGLIEGVMDIARDIAGKSPIAVTGTKEMISYMRDHRIDDGLEYV
ATWNAAMLQSNDLRVAMAAHMSKQKPEFLD

Sequences:

>Translated_270_residues
MTQYTAFSVELADNIAHVQINRPEKINSMNAAFWSEIVEVFQWIDDTDEVRVVVLSGAGKHFSSGIDLMMLAGVANELGK
DVGRNARLLRKKILTLQASFNAVDNCRKPVLAAIQGYCLGGAIDLIAACDMRYAAEDAQFSIKEIDIGMAADVGTLQRLP
RIIGDGMLRELAYTGRTFGAEEARSIGLVNRVYSDKDGLIEGVMDIARDIAGKSPIAVTGTKEMISYMRDHRIDDGLEYV
ATWNAAMLQSNDLRVAMAAHMSKQKPEFLD
>Mature_269_residues
TQYTAFSVELADNIAHVQINRPEKINSMNAAFWSEIVEVFQWIDDTDEVRVVVLSGAGKHFSSGIDLMMLAGVANELGKD
VGRNARLLRKKILTLQASFNAVDNCRKPVLAAIQGYCLGGAIDLIAACDMRYAAEDAQFSIKEIDIGMAADVGTLQRLPR
IIGDGMLRELAYTGRTFGAEEARSIGLVNRVYSDKDGLIEGVMDIARDIAGKSPIAVTGTKEMISYMRDHRIDDGLEYVA
TWNAAMLQSNDLRVAMAAHMSKQKPEFLD

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI70995211, Length=242, Percent_Identity=49.1735537190083, Blast_Score=250, Evalue=1e-66,
Organism=Homo sapiens, GI194097323, Length=258, Percent_Identity=27.1317829457364, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI20127408, Length=183, Percent_Identity=31.1475409836066, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI31542718, Length=257, Percent_Identity=25.6809338521401, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI260274832, Length=224, Percent_Identity=25.4464285714286, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI45643119, Length=224, Percent_Identity=25.4464285714286, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI260275230, Length=224, Percent_Identity=25.4464285714286, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI68989263, Length=194, Percent_Identity=28.8659793814433, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI4502327, Length=254, Percent_Identity=26.3779527559055, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI221136756, Length=224, Percent_Identity=23.2142857142857, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI221136753, Length=224, Percent_Identity=23.2142857142857, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI221307494, Length=224, Percent_Identity=23.2142857142857, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI116235487, Length=148, Percent_Identity=29.7297297297297, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI37594469, Length=220, Percent_Identity=27.2727272727273, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI37594471, Length=220, Percent_Identity=27.2727272727273, Blast_Score=68, Evalue=7e-12,
Organism=Escherichia coli, GI221142681, Length=259, Percent_Identity=30.8880308880309, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1787659, Length=250, Percent_Identity=26.8, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1788682, Length=212, Percent_Identity=31.1320754716981, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1787660, Length=258, Percent_Identity=26.7441860465116, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI87082183, Length=270, Percent_Identity=24.0740740740741, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788597, Length=259, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790281, Length=201, Percent_Identity=25.8706467661692, Blast_Score=72, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17534483, Length=260, Percent_Identity=45, Blast_Score=245, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI17536985, Length=261, Percent_Identity=42.911877394636, Blast_Score=232, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI17554946, Length=256, Percent_Identity=27.34375, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI25145438, Length=257, Percent_Identity=29.9610894941634, Blast_Score=122, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17560910, Length=223, Percent_Identity=28.6995515695067, Blast_Score=101, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17540714, Length=215, Percent_Identity=33.0232558139535, Blast_Score=100, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17558304, Length=199, Percent_Identity=30.1507537688442, Blast_Score=87, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI25144276, Length=200, Percent_Identity=30.5, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17508951, Length=200, Percent_Identity=30.5, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17508953, Length=200, Percent_Identity=30.5, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17535521, Length=194, Percent_Identity=23.7113402061856, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17540306, Length=249, Percent_Identity=24.0963855421687, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI25141363, Length=182, Percent_Identity=26.9230769230769, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6320241, Length=201, Percent_Identity=25.8706467661692, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI19920382, Length=258, Percent_Identity=43.7984496124031, Blast_Score=223, Evalue=1e-58,
Organism=Drosophila melanogaster, GI20129971, Length=257, Percent_Identity=26.0700389105058, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24653477, Length=257, Percent_Identity=26.0700389105058, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24653139, Length=258, Percent_Identity=27.906976744186, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21357171, Length=187, Percent_Identity=31.5508021390374, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24654903, Length=190, Percent_Identity=25.7894736842105, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24650670, Length=210, Percent_Identity=30.952380952381, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI19921000, Length=186, Percent_Identity=26.3440860215054, Blast_Score=64, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24583077, Length=185, Percent_Identity=26.4864864864865, Blast_Score=64, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24583079, Length=185, Percent_Identity=26.4864864864865, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 29652; Mature: 29521

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQYTAFSVELADNIAHVQINRPEKINSMNAAFWSEIVEVFQWIDDTDEVRVVVLSGAGK
CCCEEEEEEEECCCEEEEEECCCHHHCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCC
HFSSGIDLMMLAGVANELGKDVGRNARLLRKKILTLQASFNAVDNCRKPVLAAIQGYCLG
HHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAIDLIAACDMRYAAEDAQFSIKEIDIGMAADVGTLQRLPRIIGDGMLRELAYTGRTFGA
HHHHHHHHHHHHHHCCCCCEEHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCH
EEARSIGLVNRVYSDKDGLIEGVMDIARDIAGKSPIAVTGTKEMISYMRDHRIDDGLEYV
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHCCCCCCHHHH
ATWNAAMLQSNDLRVAMAAHMSKQKPEFLD
HHCCHHHHCCCCCEEHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TQYTAFSVELADNIAHVQINRPEKINSMNAAFWSEIVEVFQWIDDTDEVRVVVLSGAGK
CCEEEEEEEECCCEEEEEECCCHHHCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCC
HFSSGIDLMMLAGVANELGKDVGRNARLLRKKILTLQASFNAVDNCRKPVLAAIQGYCLG
HHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAIDLIAACDMRYAAEDAQFSIKEIDIGMAADVGTLQRLPRIIGDGMLRELAYTGRTFGA
HHHHHHHHHHHHHHCCCCCEEHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCH
EEARSIGLVNRVYSDKDGLIEGVMDIARDIAGKSPIAVTGTKEMISYMRDHRIDDGLEYV
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHCCCCCCHHHH
ATWNAAMLQSNDLRVAMAAHMSKQKPEFLD
HHCCHHHHCCCCCEEHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA