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The map label for this gene is aaeR [H]

Identifier: 77459029

GI number: 77459029

Start: 3230839

End: 3231765

Strand: Reverse

Name: aaeR [H]

Synonym: Pfl01_2804

Alternate gene names: 77459029

Gene position: 3231765-3230839 (Counterclockwise)

Preceding gene: 77459052

Following gene: 77459027

Centisome position: 50.2

GC content: 57.17

Gene sequence:

>927_bases
ATGGATAAACTTTCAAATATGTCGGTGTACGTAAAAGTGGTCGAGATGGGCAGTTTCACGGCCGTTGCGAACCATCTGGA
CTCCACTGTCGGCAATGTCTCGCGCGCCGTCTCGGCACTTGAAAATGTGCTCGATGCGCGTCTGTTGCAACGATCTACCC
GACGTCTTTCGGTGACCGACGCGGGTCGTCGGTTCTACGAGCGATGCATCAAGATCCTGGCTGACCTGGAAAGTGCAGAA
GCAGAAGCGAGCAATGCAGCCTTGAAGCCCAGGGGAACCTTGCGCGTGCACTGCGTACCTGGACTTGCTCGGCACCTGGT
GACCGGCGCAGTGCTGGCGTACCGCAATGAATTTCCGGACGTCACCGTGGATTTGATGCTCTCGCAGCGCATGCCCAACC
TGCTCGAGGACCAGTTGGATGTCTCGATCCTGATTGCCCGTACGCTGCCGGATTCAGCGTATGTCAGTCAGAAGATCGGC
GTCAGTCATTGCGTTCTGGCCGCGTCGCCCGACTATCTGGAACGACACGGAACCCCGACCACGCCTGACGAACTCAGCGC
TCATCAATGCTTGCTGCTCGGAACGGTGGACTATGTGCGGGATGAGTGGCAGCTCAAGAGCAAAGCAGGTGACGCGACCT
TCGTTCCCACCGGACCGAGCTTCAGCGTGAATGACATGGACGCGATGGCGGTCGCCATTCGGCAAGGGGCCGGTATCGGC
TTGCTGGCTGGATTTACCGCTATCGATGATTTTCGCTCTGGCCAACTGGTTCGGGTTCTGCCTGACTACCATACGTATGA
GCGAAACGTGTATGCGGTCTACACGTCTCGACAGTTCGTCGATGCCAAGATCACACGCTTTATCGACAGTTTGAAGGACC
GTGTGGGGAGTCAGCTGGCAGCAACGGCTCAGGCACTTATCGATTGA

Upstream 100 bases:

>100_bases
GGGAATCATTGTTGTCCCCAGAGGTAATATCGGGGGGCCGGGGGAGGGTGTAGCATCCGCACTTGTCTCAAGCGGATTGC
AGGTCTGAAGGACGATCAGG

Downstream 100 bases:

>100_bases
AAGCCCCAGGCCGCATCGGTGAGGCAGGGGACTGCAAGGATTGAATGCCGCGCATCCCCGGTTGCGCGGCAAGATAGTGT
TTCGAGACTCAGCAAGCGAT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MDKLSNMSVYVKVVEMGSFTAVANHLDSTVGNVSRAVSALENVLDARLLQRSTRRLSVTDAGRRFYERCIKILADLESAE
AEASNAALKPRGTLRVHCVPGLARHLVTGAVLAYRNEFPDVTVDLMLSQRMPNLLEDQLDVSILIARTLPDSAYVSQKIG
VSHCVLAASPDYLERHGTPTTPDELSAHQCLLLGTVDYVRDEWQLKSKAGDATFVPTGPSFSVNDMDAMAVAIRQGAGIG
LLAGFTAIDDFRSGQLVRVLPDYHTYERNVYAVYTSRQFVDAKITRFIDSLKDRVGSQLAATAQALID

Sequences:

>Translated_308_residues
MDKLSNMSVYVKVVEMGSFTAVANHLDSTVGNVSRAVSALENVLDARLLQRSTRRLSVTDAGRRFYERCIKILADLESAE
AEASNAALKPRGTLRVHCVPGLARHLVTGAVLAYRNEFPDVTVDLMLSQRMPNLLEDQLDVSILIARTLPDSAYVSQKIG
VSHCVLAASPDYLERHGTPTTPDELSAHQCLLLGTVDYVRDEWQLKSKAGDATFVPTGPSFSVNDMDAMAVAIRQGAGIG
LLAGFTAIDDFRSGQLVRVLPDYHTYERNVYAVYTSRQFVDAKITRFIDSLKDRVGSQLAATAQALID
>Mature_308_residues
MDKLSNMSVYVKVVEMGSFTAVANHLDSTVGNVSRAVSALENVLDARLLQRSTRRLSVTDAGRRFYERCIKILADLESAE
AEASNAALKPRGTLRVHCVPGLARHLVTGAVLAYRNEFPDVTVDLMLSQRMPNLLEDQLDVSILIARTLPDSAYVSQKIG
VSHCVLAASPDYLERHGTPTTPDELSAHQCLLLGTVDYVRDEWQLKSKAGDATFVPTGPSFSVNDMDAMAVAIRQGAGIG
LLAGFTAIDDFRSGQLVRVLPDYHTYERNVYAVYTSRQFVDAKITRFIDSLKDRVGSQLAATAQALID

Specific function: Activates transcription of the aaeXAB operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=297, Percent_Identity=35.016835016835, Blast_Score=172, Evalue=4e-44,
Organism=Escherichia coli, GI1786401, Length=291, Percent_Identity=33.6769759450172, Blast_Score=148, Evalue=5e-37,
Organism=Escherichia coli, GI87081978, Length=289, Percent_Identity=31.4878892733564, Blast_Score=144, Evalue=5e-36,
Organism=Escherichia coli, GI1789440, Length=287, Percent_Identity=28.5714285714286, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI145693193, Length=291, Percent_Identity=28.1786941580756, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1787128, Length=292, Percent_Identity=26.7123287671233, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1787589, Length=304, Percent_Identity=25.6578947368421, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1786448, Length=242, Percent_Identity=26.8595041322314, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788481, Length=293, Percent_Identity=22.8668941979522, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788297, Length=142, Percent_Identity=30.9859154929577, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33690; Mature: 33690

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLSNMSVYVKVVEMGSFTAVANHLDSTVGNVSRAVSALENVLDARLLQRSTRRLSVTD
CCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEHHH
AGRRFYERCIKILADLESAEAEASNAALKPRGTLRVHCVPGLARHLVTGAVLAYRNEFPD
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHCCCCC
VTVDLMLSQRMPNLLEDQLDVSILIARTLPDSAYVSQKIGVSHCVLAASPDYLERHGTPT
HHHHHHHHHHCHHHHHHHCCEEEEEEECCCCHHHHHHHCCHHHEEEECCCHHHHHCCCCC
TPDELSAHQCLLLGTVDYVRDEWQLKSKAGDATFVPTGPSFSVNDMDAMAVAIRQGAGIG
CHHHHCCCCEEEEECHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHCCCCEE
LLAGFTAIDDFRSGQLVRVLPDYHTYERNVYAVYTSRQFVDAKITRFIDSLKDRVGSQLA
HHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
ATAQALID
HHHHHHCC
>Mature Secondary Structure
MDKLSNMSVYVKVVEMGSFTAVANHLDSTVGNVSRAVSALENVLDARLLQRSTRRLSVTD
CCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEHHH
AGRRFYERCIKILADLESAEAEASNAALKPRGTLRVHCVPGLARHLVTGAVLAYRNEFPD
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHCCCCC
VTVDLMLSQRMPNLLEDQLDVSILIARTLPDSAYVSQKIGVSHCVLAASPDYLERHGTPT
HHHHHHHHHHCHHHHHHHCCEEEEEEECCCCHHHHHHHCCHHHEEEECCCHHHHHCCCCC
TPDELSAHQCLLLGTVDYVRDEWQLKSKAGDATFVPTGPSFSVNDMDAMAVAIRQGAGIG
CHHHHCCCCEEEEECHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHCCCCEE
LLAGFTAIDDFRSGQLVRVLPDYHTYERNVYAVYTSRQFVDAKITRFIDSLKDRVGSQLA
HHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
ATAQALID
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]