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The map label for this gene is yfnA [H]

Identifier: 77459018

GI number: 77459018

Start: 3217164

End: 3218480

Strand: Reverse

Name: yfnA [H]

Synonym: Pfl01_2793

Alternate gene names: 77459018

Gene position: 3218480-3217164 (Counterclockwise)

Preceding gene: 77459019

Following gene: 77459015

Centisome position: 49.99

GC content: 55.81

Gene sequence:

>1317_bases
GTGATGACCTTGCCCTCCAAGACCTCCCTGCGCCGGGCCGTTACCGGCCCGATGCTTTTTCTATTTATTCTCGGCGATGT
GCTCGGGGCGGGCGTTTATGCTCTTGCCGGGACAATTGCAGGGGAGGTGGGTGGCGCAATATGGATGCCGCTGCTGATTG
CTCTTTTTTTCGCGATGCTTACTGCAGGTTCCTATGCCGAGTTGGTGACAAAATATCCCCACGCGGGCGCCGCTTCGGTT
TTCGCCGAGAAAGCGTTCGGGTCACCGCTCATTTCTTTTCTCGTGGGCTTTTGCATGCTATCTGCAGCTGTCACGAGCGC
TGCGGGTTTATCGCTGGCGTTTGCGGGTGATTACCTGGCGGCGTTCATCCATGTACCACCTCACATTTCAGCCTTACTGT
TCCTTCTCGTGATCGCGCTACTCAATGCGAGGGGAATTAAAGAATCCTTGGGAGCCAACTTGGTGATGACAGTCATTGAG
CTGTCAGGCCTTCTTTTGGTCGTTGTTGCCGCCGCCTGGTATTTCCGTACAGGTGATGCAGATTTGGGTCGCAGCCTGGA
GTTCAAGCCGGGAGTCAGCCCGGTGTTAGCCGTTTTGGGGGCGGCACTGATCGCCTTCTATTCTTTTGTAGGATTCGAAA
CATCCGCCAATCTTGCAGAAGAAATTCGAGACGTTCGAAAAGTCTACCCCCGCGCATTGTTTGGCGCATTGCTGACCGCC
GGAGTCCTCTACATGGCGGTCGGTGTAGCTGCATCTTCCGTACTGCCCATGGAAAAACTGGTTGCAACCTCTGCTCCTCT
TCTTGAGGTGGTTCGGGCGTCAGGTTTGAACATCCCGCCTCGCGTCTTTGCCTTTATTGCATTGGTCGCGGTAGCCAACG
GCGCACTTCTAACCATGATAATGGCCAGCCGCCTTACTTATGGCATGGCCTGCCTTGGACTTTTGCCGAATGCCTTGAGC
AAAGTGCTGCCTCAACGACGCACCCCGTGGATAGCAGTGATCGCTACCACCCTCGTAGCAATCGGGCTCACGCTGACGGG
GACGCTAGCCACGCTCGCTGAAACGGTCGTCCTGCTCCTGCTGTTCGTATTTCTCAGTACCAATTTGTCCGTGTTGATCC
TGCGCCGTGACGAGGTTGCGCAAGATCATTTTCGAGTACCTACGTGGGTTCCGCTACTTGCTATCGTCTCGTGCCTGGTA
CTGCTTAGTCAGCAAAGTCTGGAAACCTGGATGCGTGGAGGCGCGCTGATCCTGACAGGCATGCTGCTTTTCGCCTGTGC
AAGAGTGGCACTGCCGGCGCCAGTGGAGCCTGGCTAG

Upstream 100 bases:

>100_bases
TGAACTTTAGTGATACGCGAATTTCCATTGCTTGAGAGTGAAGCCGCCTGGCTTCCAGCCCGGTAATCGGCCCTCCGAAC
CTCAAGTCAGGAAGTAGATC

Downstream 100 bases:

>100_bases
GCTTGTAAGCGCTTTCCCTGTCTACCGCAGCGTTAACTTGGCTACGTCATACAAATGCCAGAGGGCGAGCGGTTGTATTG
GGTGCATCCGACCTAGGATC

Product: amino acid permease-associated protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MMTLPSKTSLRRAVTGPMLFLFILGDVLGAGVYALAGTIAGEVGGAIWMPLLIALFFAMLTAGSYAELVTKYPHAGAASV
FAEKAFGSPLISFLVGFCMLSAAVTSAAGLSLAFAGDYLAAFIHVPPHISALLFLLVIALLNARGIKESLGANLVMTVIE
LSGLLLVVVAAAWYFRTGDADLGRSLEFKPGVSPVLAVLGAALIAFYSFVGFETSANLAEEIRDVRKVYPRALFGALLTA
GVLYMAVGVAASSVLPMEKLVATSAPLLEVVRASGLNIPPRVFAFIALVAVANGALLTMIMASRLTYGMACLGLLPNALS
KVLPQRRTPWIAVIATTLVAIGLTLTGTLATLAETVVLLLLFVFLSTNLSVLILRRDEVAQDHFRVPTWVPLLAIVSCLV
LLSQQSLETWMRGGALILTGMLLFACARVALPAPVEPG

Sequences:

>Translated_438_residues
MMTLPSKTSLRRAVTGPMLFLFILGDVLGAGVYALAGTIAGEVGGAIWMPLLIALFFAMLTAGSYAELVTKYPHAGAASV
FAEKAFGSPLISFLVGFCMLSAAVTSAAGLSLAFAGDYLAAFIHVPPHISALLFLLVIALLNARGIKESLGANLVMTVIE
LSGLLLVVVAAAWYFRTGDADLGRSLEFKPGVSPVLAVLGAALIAFYSFVGFETSANLAEEIRDVRKVYPRALFGALLTA
GVLYMAVGVAASSVLPMEKLVATSAPLLEVVRASGLNIPPRVFAFIALVAVANGALLTMIMASRLTYGMACLGLLPNALS
KVLPQRRTPWIAVIATTLVAIGLTLTGTLATLAETVVLLLLFVFLSTNLSVLILRRDEVAQDHFRVPTWVPLLAIVSCLV
LLSQQSLETWMRGGALILTGMLLFACARVALPAPVEPG
>Mature_438_residues
MMTLPSKTSLRRAVTGPMLFLFILGDVLGAGVYALAGTIAGEVGGAIWMPLLIALFFAMLTAGSYAELVTKYPHAGAASV
FAEKAFGSPLISFLVGFCMLSAAVTSAAGLSLAFAGDYLAAFIHVPPHISALLFLLVIALLNARGIKESLGANLVMTVIE
LSGLLLVVVAAAWYFRTGDADLGRSLEFKPGVSPVLAVLGAALIAFYSFVGFETSANLAEEIRDVRKVYPRALFGALLTA
GVLYMAVGVAASSVLPMEKLVATSAPLLEVVRASGLNIPPRVFAFIALVAVANGALLTMIMASRLTYGMACLGLLPNALS
KVLPQRRTPWIAVIATTLVAIGLTLTGTLATLAETVVLLLLFVFLSTNLSVLILRRDEVAQDHFRVPTWVPLLAIVSCLV
LLSQQSLETWMRGGALILTGMLLFACARVALPAPVEPG

Specific function: Probable Amino-Acid Or Metabolite Transport Protein. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=410, Percent_Identity=26.5853658536585, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI258614003, Length=410, Percent_Identity=26.5853658536585, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI258614005, Length=410, Percent_Identity=26.5853658536585, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI258645169, Length=410, Percent_Identity=26.0975609756098, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI181337167, Length=386, Percent_Identity=26.1658031088083, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI114326544, Length=408, Percent_Identity=26.9607843137255, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI114326550, Length=408, Percent_Identity=26.9607843137255, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI110347453, Length=354, Percent_Identity=28.2485875706215, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI87081869, Length=392, Percent_Identity=25.5102040816327, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI87082023, Length=421, Percent_Identity=25.8907363420428, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI87082250, Length=398, Percent_Identity=23.3668341708543, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790653, Length=437, Percent_Identity=24.2562929061785, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786694, Length=368, Percent_Identity=23.3695652173913, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786302, Length=420, Percent_Identity=22.3809523809524, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI87081708, Length=432, Percent_Identity=23.1481481481481, Blast_Score=62, Evalue=7e-11,
Organism=Escherichia coli, GI1790584, Length=255, Percent_Identity=30.9803921568627, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17531343, Length=403, Percent_Identity=27.5434243176179, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17533459, Length=423, Percent_Identity=25.0591016548463, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17532491, Length=397, Percent_Identity=24.6851385390428, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI71990446, Length=414, Percent_Identity=25.3623188405797, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI32566699, Length=301, Percent_Identity=26.2458471760797, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI193208714, Length=407, Percent_Identity=23.8329238329238, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI32566695, Length=407, Percent_Identity=23.8329238329238, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24667468, Length=429, Percent_Identity=27.7389277389277, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI221512776, Length=397, Percent_Identity=27.2040302267003, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24666159, Length=397, Percent_Identity=27.2040302267003, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI161077963, Length=393, Percent_Identity=25.1908396946565, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24668806, Length=392, Percent_Identity=26.7857142857143, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI21356285, Length=392, Percent_Identity=26.7857142857143, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24668802, Length=392, Percent_Identity=26.7857142857143, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24651635, Length=409, Percent_Identity=25.9168704156479, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24651633, Length=409, Percent_Identity=25.9168704156479, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI281366235, Length=388, Percent_Identity=27.0618556701031, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI116007820, Length=388, Percent_Identity=27.0618556701031, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 45960; Mature: 45960

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]