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The map label for this gene is nhaB [H]

Identifier: 77458814

GI number: 77458814

Start: 2966720

End: 2968222

Strand: Reverse

Name: nhaB [H]

Synonym: Pfl01_2589

Alternate gene names: 77458814

Gene position: 2968222-2966720 (Counterclockwise)

Preceding gene: 77458815

Following gene: 77458810

Centisome position: 46.1

GC content: 60.88

Gene sequence:

>1503_bases
ATGTCCGGTTCGATGGCCCAAGCGTTCGCGCACAACTTTCTCGGGCATTCGCCCCGCTGGTACAAGGCGTGCATCGTCGG
GTTTCTGATGCTCAACGCGCTGGTGCTGTGGAGCGTCGGTCCGGTCGCCGCTGGCTGGTTGCTGGTGATTGAGTTCATTT
TCACCCTGGCCATGGCGCTCAAGTGCTACCCCCTGATGCCCGGCGGTTTGCTGCTGATCGAAGCGCTGCTGCTGAAAATG
ACCACGCCCCAGGCGCTGTATGAAGAGCTGCAGCACAATTTCCCGGTGATTCTGCTGCTGATGTTCATGGTCGCCGGCAT
CTACTTCATGAAAGACCTGCTGCTGTTCCTGTTCTCGCGCCTGTTGCTGGGCGTGCGTTCGAAGGCGCTGCTGGCCCTGA
TGTTCTGCTTTCTGTCGGCATTTCTTTCGGCGTTTCTCGACGCACTGACCGTCACCGCAGTGATCATCAGCGCCGCCGTG
GGCTTCTATTCGGTTTATCACCGGGTGGCCTCCGGCAACGATCCACGCCAGGACAGCGAATTCAGCGATGACCAGCATCT
GCCTCAACTGCATCACGAGGACTTGGAGCAGTTTCGCGCCTTCCTGCGCAGCCTGTTGATGCACGGCGCTGTCGGCACTG
CATTGGGTGGCGTCTGCACCCTGGTGGGTGAGCCACAAAACCTGCTGATTGGTCACGAGATGGGCTGGCACTTCGCCGAG
TTTTTCCTGAAGGTCGCGCCGGTGTCGCTGCCGGTTCTGGTTGCGGGACTGGTGACCTGCCTGCTGCTGGAGAAATTGCG
CTGGTTCGGTTACGGCACGCTGCTGCCGGACAACGTACGTGCCGTGCTGGCCAACTACGCCGCCGAAGACAACGCGGAGC
GCACCCCGCGCCAACGCGCCGCCCTGCTGGTGCAAGGCTGCGCTGCGCTGATCCTGATCGCCGGGCTGGCGTTCCATATC
GCGGAAGTCGGCTTGATCGGACTGATGGTGATTGTGTTGATCACTGCGTTCACCGGGATCACCGACGAGCACCGACTGGG
CAGCGCATTCAAGGACGCGATGCCGTTCACCGCGTTGCTGGTGGTGTTCTTCGCCGTGGTCGCGGTGATTCACGACCAGC
AACTGTTCGCGCCGCTGATTCAGTGGGTGCTGGCACTGCCGGCCGACCAGCAACCGGGGATGCTGTTCATCGCTAACGGC
CTGCTGTCGGCGATCAGTGACAACGTGTTCGTTGCCACGATCTATATCACTGAAGTAAAACAGGCTTTCCTGTCCGGACA
CATGAGCCGCGAGCACTTCGAGACGCTGGCAATTGCGATCAACACCGGCACCAATCTGCCGAGCGTGGCGACGCCCAATG
GTCAGGCGGCGTTTCTGTTTCTGCTGACGTCGGCGATTGCACCGCTGGTACGGTTGTCGTACGGGCGGATGGTGTGGATG
GCGTTGCCTTACACCGTGGTGATGGGATTGCTCGGCTGGTACGCCGTGAGCTACTGGCTGTAG

Upstream 100 bases:

>100_bases
TAGTCGCGCGTTATCTGAATCATTGATGCGAACCTTCCTACACTTGATCTTGCCCATGGCTTACGGCAACTTGCGCGCTT
CTTAATACAAGGAGCAACCG

Downstream 100 bases:

>100_bases
AAACAACAACGGGAGCCCTGGGGCTCCCGTTTTTTTATACATAAATCAGCGCGGCAATATGTGCTGCTCGATGGCCTGCG
CCACACCGTCCTCGGTGTTG

Product: sodium/proton antiporter

Products: Na (I) [Periplasm]; Proton [Cytoplasm] [C]

Alternate protein names: Sodium/proton antiporter nhaB [H]

Number of amino acids: Translated: 500; Mature: 499

Protein sequence:

>500_residues
MSGSMAQAFAHNFLGHSPRWYKACIVGFLMLNALVLWSVGPVAAGWLLVIEFIFTLAMALKCYPLMPGGLLLIEALLLKM
TTPQALYEELQHNFPVILLLMFMVAGIYFMKDLLLFLFSRLLLGVRSKALLALMFCFLSAFLSAFLDALTVTAVIISAAV
GFYSVYHRVASGNDPRQDSEFSDDQHLPQLHHEDLEQFRAFLRSLLMHGAVGTALGGVCTLVGEPQNLLIGHEMGWHFAE
FFLKVAPVSLPVLVAGLVTCLLLEKLRWFGYGTLLPDNVRAVLANYAAEDNAERTPRQRAALLVQGCAALILIAGLAFHI
AEVGLIGLMVIVLITAFTGITDEHRLGSAFKDAMPFTALLVVFFAVVAVIHDQQLFAPLIQWVLALPADQQPGMLFIANG
LLSAISDNVFVATIYITEVKQAFLSGHMSREHFETLAIAINTGTNLPSVATPNGQAAFLFLLTSAIAPLVRLSYGRMVWM
ALPYTVVMGLLGWYAVSYWL

Sequences:

>Translated_500_residues
MSGSMAQAFAHNFLGHSPRWYKACIVGFLMLNALVLWSVGPVAAGWLLVIEFIFTLAMALKCYPLMPGGLLLIEALLLKM
TTPQALYEELQHNFPVILLLMFMVAGIYFMKDLLLFLFSRLLLGVRSKALLALMFCFLSAFLSAFLDALTVTAVIISAAV
GFYSVYHRVASGNDPRQDSEFSDDQHLPQLHHEDLEQFRAFLRSLLMHGAVGTALGGVCTLVGEPQNLLIGHEMGWHFAE
FFLKVAPVSLPVLVAGLVTCLLLEKLRWFGYGTLLPDNVRAVLANYAAEDNAERTPRQRAALLVQGCAALILIAGLAFHI
AEVGLIGLMVIVLITAFTGITDEHRLGSAFKDAMPFTALLVVFFAVVAVIHDQQLFAPLIQWVLALPADQQPGMLFIANG
LLSAISDNVFVATIYITEVKQAFLSGHMSREHFETLAIAINTGTNLPSVATPNGQAAFLFLLTSAIAPLVRLSYGRMVWM
ALPYTVVMGLLGWYAVSYWL
>Mature_499_residues
SGSMAQAFAHNFLGHSPRWYKACIVGFLMLNALVLWSVGPVAAGWLLVIEFIFTLAMALKCYPLMPGGLLLIEALLLKMT
TPQALYEELQHNFPVILLLMFMVAGIYFMKDLLLFLFSRLLLGVRSKALLALMFCFLSAFLSAFLDALTVTAVIISAAVG
FYSVYHRVASGNDPRQDSEFSDDQHLPQLHHEDLEQFRAFLRSLLMHGAVGTALGGVCTLVGEPQNLLIGHEMGWHFAEF
FLKVAPVSLPVLVAGLVTCLLLEKLRWFGYGTLLPDNVRAVLANYAAEDNAERTPRQRAALLVQGCAALILIAGLAFHIA
EVGLIGLMVIVLITAFTGITDEHRLGSAFKDAMPFTALLVVFFAVVAVIHDQQLFAPLIQWVLALPADQQPGMLFIANGL
LSAISDNVFVATIYITEVKQAFLSGHMSREHFETLAIAINTGTNLPSVATPNGQAAFLFLLTSAIAPLVRLSYGRMVWMA
LPYTVVMGLLGWYAVSYWL

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG3067

COG function: function code P; Na+/H+ antiporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nhaB Na(+)/H(+) (TC 2.A.34) antiporter family [H]

Homologues:

Organism=Escherichia coli, GI1787435, Length=484, Percent_Identity=61.9834710743802, Blast_Score=592, Evalue=1e-170,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004671 [H]

Pfam domain/function: PF06450 NhaB [H]

EC number: NA

Molecular weight: Translated: 54796; Mature: 54665

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SGSMAQAFAHNFLGHSPRWYKACIVGFLMLNALVLWSVGPVAAGWLLVIEFIFTLAMAL
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
KCYPLMPGGLLLIEALLLKMTTPQALYEELQHNFPVILLLMFMVAGIYFMKDLLLFLFSR
HHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLGVRSKALLALMFCFLSAFLSAFLDALTVTAVIISAAVGFYSVYHRVASGNDPRQDSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
FSDDQHLPQLHHEDLEQFRAFLRSLLMHGAVGTALGGVCTLVGEPQNLLIGHEMGWHFAE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHH
FFLKVAPVSLPVLVAGLVTCLLLEKLRWFGYGTLLPDNVRAVLANYAAEDNAERTPRQRA
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHH
ALLVQGCAALILIAGLAFHIAEVGLIGLMVIVLITAFTGITDEHRLGSAFKDAMPFTALL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHH
VVFFAVVAVIHDQQLFAPLIQWVLALPADQQPGMLFIANGLLSAISDNVFVATIYITEVK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHCCCEEEEEHHHHHHH
QAFLSGHMSREHFETLAIAINTGTNLPSVATPNGQAAFLFLLTSAIAPLVRLSYGRMVWM
HHHHHCCCCHHHHHHHHEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ALPYTVVMGLLGWYAVSYWL
HHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 3 Proton [Periplasm]; Na (I) [Cytoplasm] [C]

Specific reaction: 3 Proton [Periplasm] + 2 Na (I) [Cytoplasm] = 2 Na (I) [Periplasm] + 3 Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA