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The map label for this gene is hlyB [H]

Identifier: 77458779

GI number: 77458779

Start: 2924537

End: 2926528

Strand: Reverse

Name: hlyB [H]

Synonym: Pfl01_2554

Alternate gene names: 77458779

Gene position: 2926528-2924537 (Counterclockwise)

Preceding gene: 77458781

Following gene: 77458778

Centisome position: 45.45

GC content: 62.0

Gene sequence:

>1992_bases
ATGCCCGCATTCCGCACCATTCAGGCTCGCTACACGCTGTTTCTGGTTCTGTTCATTTTGTTGCTGTCGGTGCTGACCGT
GGTCGGCATCAGCCAGCTGGTCGCGCCCAAGCTGCGCCATACCGAAGAACAAGTCGTGCTCAACCGCATTGCGGAAGTGG
CCGAGCAGATCCAGGGCGAATTGAACAAGGTCCAGGCGCAACAGCGCAGCATCACCCAGACCATCCCGCTGCTCGACAGC
GCGGCCATCGACAGCGTGTTGCCGGGGCTGGTCGATCAATATGGCGAACTGAAAGTGTTCGGCGGCGGCATCTGGCCATT
GCCCGGTCAGCGTGAGGCCGGACGCAACAAGTTCAGTACGTTCTGGCACCGGGATGCCTCCGGCAAACTGGCGGTGAACA
CGTTCTGGAACAGCGACGCGGCCCCCAACTATTACGACCAGAGCTGGTACAAGGGCGGCATGCAGACCCCGCGCGGCCAA
TGCGCGTGGGCCGCTGCCTATAAAGATGACGCCAGCGCCGAACCGCGCACCAACTGCGCCATGGCCATCCAGAAAAACGG
CAGCGCCTGGGGCGTCTCGACCATCGACGTGACCCTGGGCTTCTTCAACGATCTGGTGGCGCGCAAGGAAAAAGACCTCA
ACGCCGAAATGCTGATCGTCGAGGCCGACGGCAAGATCATCAGCAACAGCTCGCGTATCAACGGGCCGATCGTGCTGAAG
AACATCAGCGAACTGGCCGGCGGCTCGACCTTCGCCAGCCAGATCAAAGCCGGGCTGCAAAACCGCGAGCAGGCACAGCG
TGTCGAGTTCGACAACCACGGTGAAGCCAGCACCTTCTTCATGCGCCCAATCGAAGGCACCCCGTGGTTCCTCGCCACCG
CGCTGCCGACCAAGATGCTCACCGCCCAGCGTGACGACGTACTCAGCAGCCTGAGTCTGCTGCAGATTCCGCTGGTGATC
CTGCTGGTGCTGTTGCAGGTCTACGCGATCCGCCAACTGGTCTCGCGCATGAAAGCGCTGAAGGCCAATATCGATTCACT
GTCCAGCGGCGATGCCGACCTGACCCGGCGCATCACCATCCGCGCTGAAGATGAACTCGGTGCCATCGGGCATTCAGTCA
ACACCTTCATCGCCTACCTGCAGAACATGATCGGCGAAGTGACCCAGGCTACCGGCGCCATGGCCTCGAGCCTCGACAAC
CTGCAGCGCACCTCGGCGCACACCAGCCAGATTCTGCTGCGCCACGCTTCGGAAACCGACCAGACCGTTACCGCGATCAA
CGAAATGAGCTCGACTGCCGAAAGCGTCGCGCAGAACGCTGCCGAAACCGCTGCCTTCACCCAGCGCGCCAACGAAAACG
CCGACCGTTCCCGCATCGTGGTCGGTGAAGCGTCAAGCAGCGTAGTGGCGTTGATCGACGAAGTGGCCAGCGCCACCCAC
AAGGTAGAAAGCATGCAGCAGGACGCCCAGCGCATCACCGAAATCCTCGGCGTGATCGGCGCCATTGCCGGCCAGACCAA
CCTGCTGGCGCTCAACGCTGCGATTGAAGCGGCCCGCGCCGGTGAACAGGGTCGCGGTTTTGCCGTGGTAGCGGACGAAG
TACGAGCCCTCGCCGCCCGCACCCAGGCCAGCACCTCGGAAATCAACGAAATGTTGAGCCGTCTGACCCAAGGTGTGAGT
TCCTCGGTCAGCGCCATGGAAAACACTCAGGCCAGTTGTCAGTCAGCCGCCGATGCCACGGCGCGAGTCAACAGTGGCCT
CGACGAAATGGCCGGTTCGGTCAGCCACATCAACAGCCTCAGCACCCAGATCGCCACCGCCGCGGAACAACAAAGCGCAG
TCACCGAAGAGATCAACCGCAGCATGGTGCAGATCCGCCACATGGTTGATGAGCTGGTGGAAAGCGGCCAGGCCAGCGAA
CTTAACACCCGCCAGCTGCTGGAAGCCAACAGCCGGGTGAGCGCGATCATGGGGCGTTTCAAGGTGCGCTGA

Upstream 100 bases:

>100_bases
AAAGTACCTAAAGCTTCCCGAAGACCCGACGATACGTTAGGAAACCCGCGCTGCTTTTCCCCTGCCCACAATAAGAATCC
CTGCTCAAGGACCGGTTTCC

Downstream 100 bases:

>100_bases
CAGTTTTGTCATCTTGCGCTCAGTGGCCTGTCAGCTTTGATCTACGATCATGTTGGCAGGCCTGCCTCGTATCACTTGGA
AACACTCCGTTGATGCCAGG

Product: chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 663; Mature: 662

Protein sequence:

>663_residues
MPAFRTIQARYTLFLVLFILLLSVLTVVGISQLVAPKLRHTEEQVVLNRIAEVAEQIQGELNKVQAQQRSITQTIPLLDS
AAIDSVLPGLVDQYGELKVFGGGIWPLPGQREAGRNKFSTFWHRDASGKLAVNTFWNSDAAPNYYDQSWYKGGMQTPRGQ
CAWAAAYKDDASAEPRTNCAMAIQKNGSAWGVSTIDVTLGFFNDLVARKEKDLNAEMLIVEADGKIISNSSRINGPIVLK
NISELAGGSTFASQIKAGLQNREQAQRVEFDNHGEASTFFMRPIEGTPWFLATALPTKMLTAQRDDVLSSLSLLQIPLVI
LLVLLQVYAIRQLVSRMKALKANIDSLSSGDADLTRRITIRAEDELGAIGHSVNTFIAYLQNMIGEVTQATGAMASSLDN
LQRTSAHTSQILLRHASETDQTVTAINEMSSTAESVAQNAAETAAFTQRANENADRSRIVVGEASSSVVALIDEVASATH
KVESMQQDAQRITEILGVIGAIAGQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAARTQASTSEINEMLSRLTQGVS
SSVSAMENTQASCQSAADATARVNSGLDEMAGSVSHINSLSTQIATAAEQQSAVTEEINRSMVQIRHMVDELVESGQASE
LNTRQLLEANSRVSAIMGRFKVR

Sequences:

>Translated_663_residues
MPAFRTIQARYTLFLVLFILLLSVLTVVGISQLVAPKLRHTEEQVVLNRIAEVAEQIQGELNKVQAQQRSITQTIPLLDS
AAIDSVLPGLVDQYGELKVFGGGIWPLPGQREAGRNKFSTFWHRDASGKLAVNTFWNSDAAPNYYDQSWYKGGMQTPRGQ
CAWAAAYKDDASAEPRTNCAMAIQKNGSAWGVSTIDVTLGFFNDLVARKEKDLNAEMLIVEADGKIISNSSRINGPIVLK
NISELAGGSTFASQIKAGLQNREQAQRVEFDNHGEASTFFMRPIEGTPWFLATALPTKMLTAQRDDVLSSLSLLQIPLVI
LLVLLQVYAIRQLVSRMKALKANIDSLSSGDADLTRRITIRAEDELGAIGHSVNTFIAYLQNMIGEVTQATGAMASSLDN
LQRTSAHTSQILLRHASETDQTVTAINEMSSTAESVAQNAAETAAFTQRANENADRSRIVVGEASSSVVALIDEVASATH
KVESMQQDAQRITEILGVIGAIAGQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAARTQASTSEINEMLSRLTQGVS
SSVSAMENTQASCQSAADATARVNSGLDEMAGSVSHINSLSTQIATAAEQQSAVTEEINRSMVQIRHMVDELVESGQASE
LNTRQLLEANSRVSAIMGRFKVR
>Mature_662_residues
PAFRTIQARYTLFLVLFILLLSVLTVVGISQLVAPKLRHTEEQVVLNRIAEVAEQIQGELNKVQAQQRSITQTIPLLDSA
AIDSVLPGLVDQYGELKVFGGGIWPLPGQREAGRNKFSTFWHRDASGKLAVNTFWNSDAAPNYYDQSWYKGGMQTPRGQC
AWAAAYKDDASAEPRTNCAMAIQKNGSAWGVSTIDVTLGFFNDLVARKEKDLNAEMLIVEADGKIISNSSRINGPIVLKN
ISELAGGSTFASQIKAGLQNREQAQRVEFDNHGEASTFFMRPIEGTPWFLATALPTKMLTAQRDDVLSSLSLLQIPLVIL
LVLLQVYAIRQLVSRMKALKANIDSLSSGDADLTRRITIRAEDELGAIGHSVNTFIAYLQNMIGEVTQATGAMASSLDNL
QRTSAHTSQILLRHASETDQTVTAINEMSSTAESVAQNAAETAAFTQRANENADRSRIVVGEASSSVVALIDEVASATHK
VESMQQDAQRITEILGVIGAIAGQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAARTQASTSEINEMLSRLTQGVSS
SVSAMENTQASCQSAADATARVNSGLDEMAGSVSHINSLSTQIATAAEQQSAVTEEINRSMVQIRHMVDELVESGQASEL
NTRQLLEANSRVSAIMGRFKVR

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=379, Percent_Identity=27.9683377308707, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI2367378, Length=302, Percent_Identity=29.4701986754967, Blast_Score=111, Evalue=2e-25,
Organism=Escherichia coli, GI1788195, Length=297, Percent_Identity=29.6296296296296, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1787690, Length=311, Percent_Identity=30.2250803858521, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI1789453, Length=282, Percent_Identity=30.1418439716312, Blast_Score=99, Evalue=8e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 71524; Mature: 71392

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAFRTIQARYTLFLVLFILLLSVLTVVGISQLVAPKLRHTEEQVVLNRIAEVAEQIQGE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
LNKVQAQQRSITQTIPLLDSAAIDSVLPGLVDQYGELKVFGGGIWPLPGQREAGRNKFST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCHHHH
FWHRDASGKLAVNTFWNSDAAPNYYDQSWYKGGMQTPRGQCAWAAAYKDDASAEPRTNCA
HHCCCCCCCEEEEEEECCCCCCCCCCHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCEE
MAIQKNGSAWGVSTIDVTLGFFNDLVARKEKDLNAEMLIVEADGKIISNSSRINGPIVLK
EEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEECCCCCCCCCEEEH
NISELAGGSTFASQIKAGLQNREQAQRVEFDNHGEASTFFMRPIEGTPWFLATALPTKML
HHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCEEHHHHHHHHHH
TAQRDDVLSSLSLLQIPLVILLVLLQVYAIRQLVSRMKALKANIDSLSSGDADLTRRITI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCEEEEEE
RAEDELGAIGHSVNTFIAYLQNMIGEVTQATGAMASSLDNLQRTSAHTSQILLRHASETD
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
QTVTAINEMSSTAESVAQNAAETAAFTQRANENADRSRIVVGEASSSVVALIDEVASATH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHH
KVESMQQDAQRITEILGVIGAIAGQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAAR
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHHH
TQASTSEINEMLSRLTQGVSSSVSAMENTQASCQSAADATARVNSGLDEMAGSVSHINSL
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
STQIATAAEQQSAVTEEINRSMVQIRHMVDELVESGQASELNTRQLLEANSRVSAIMGRF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
KVR
CCC
>Mature Secondary Structure 
PAFRTIQARYTLFLVLFILLLSVLTVVGISQLVAPKLRHTEEQVVLNRIAEVAEQIQGE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
LNKVQAQQRSITQTIPLLDSAAIDSVLPGLVDQYGELKVFGGGIWPLPGQREAGRNKFST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCHHHH
FWHRDASGKLAVNTFWNSDAAPNYYDQSWYKGGMQTPRGQCAWAAAYKDDASAEPRTNCA
HHCCCCCCCEEEEEEECCCCCCCCCCHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCEE
MAIQKNGSAWGVSTIDVTLGFFNDLVARKEKDLNAEMLIVEADGKIISNSSRINGPIVLK
EEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEECCCCCCCCCEEEH
NISELAGGSTFASQIKAGLQNREQAQRVEFDNHGEASTFFMRPIEGTPWFLATALPTKML
HHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCEEHHHHHHHHHH
TAQRDDVLSSLSLLQIPLVILLVLLQVYAIRQLVSRMKALKANIDSLSSGDADLTRRITI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCEEEEEE
RAEDELGAIGHSVNTFIAYLQNMIGEVTQATGAMASSLDNLQRTSAHTSQILLRHASETD
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
QTVTAINEMSSTAESVAQNAAETAAFTQRANENADRSRIVVGEASSSVVALIDEVASATH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHH
KVESMQQDAQRITEILGVIGAIAGQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAAR
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHHH
TQASTSEINEMLSRLTQGVSSSVSAMENTQASCQSAADATARVNSGLDEMAGSVSHINSL
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
STQIATAAEQQSAVTEEINRSMVQIRHMVDELVESGQASELNTRQLLEANSRVSAIMGRF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
KVR
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]