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The map label for this gene is ptxB [H]

Identifier: 77458659

GI number: 77458659

Start: 2787391

End: 2788242

Strand: Reverse

Name: ptxB [H]

Synonym: Pfl01_2434

Alternate gene names: 77458659

Gene position: 2788242-2787391 (Counterclockwise)

Preceding gene: 77458660

Following gene: 77458658

Centisome position: 43.31

GC content: 62.79

Gene sequence:

>852_bases
ATGCTCAAGCGAACCCTGGCACTGACCGCTGGTTTGGCCCTGTCCCTGTCCGCCGTGCTGGCGCAAGCCGCGGAGGTGTT
GAAGGTCAGCGCGATTCCCGATGAAGCCCCGACCGAGCTGCTGCGCAAGTTCGAGCCGCTGGGCAAGTACCTGCAACAGC
AATTGGGCATGGACGTGCAGTTCGTTCCCGTGGCGGATTACCCGGCGGTGGTTGAAGCGCTGGCCACTGACCGCCTCGAT
CTGGCGTGGCTCGGCGGTTTCACCTTCGTTCAGGCGCGGCTGAAAACCGGCAACGCCATTCCGCTGGTGCAGCGTGAGCA
AGATGCGCAGTTCACCAGCAAATTCATCACCGCCGACCCGAACGTCAAAAGCCTTGCCGACCTCAAGGGCAAGACCTTCG
CCTTTGGCTCCGTGTCATCCACCTCCGGCAGCCTGATGCCGCGCTACTTCATGCTCAAGGACGGCATCAAACCGGAAAGC
TATTTCAGCCGCGTCGGCTACTCCGGCGCCCACGACGCCACCGTCGCCTGGGTGCAGGCCGGCAAGGTCGACGCCGGCGT
GCTGAACGCCAGCGTCTGGCAGAAACTGGTGGACGCCGGCAAGGTCGACACCAACAAGGTCAAGGTCTTCGCCACCACCC
CGACCTACTTCGATTACAACTGGACCGTGCGCGGCACCCTCGATCCGGCGCTGGCGGCGAAGATCAAAAAAGCCTTCCTC
GACCTCGACCCCGCCAACCCCGAGCACAAGAAAATCCTCGACCTGCAAGCCGCCAGTCGCTTCATCGAAACCAGCCCGGA
CAATTACAAAGGCATCGAGGAAGCCGCCCGCGCCGCCGACTTGCTGAAATGA

Upstream 100 bases:

>100_bases
CCTCGCACTTTCACCGTTTCGTCTAACCTGACGTTGCACCCGACGATGATTGCCCATCGACGGGTGCATCGACCTTGATG
CCCACGAAACGGAGAATTCC

Downstream 100 bases:

>100_bases
CGCTGCGCCTCAAACAGGCTTTTCTGCACCACACCAATGGCGTGGAGGCCTTGCGCGGCGTCGATTTGCAGATCGAGGCC
GGCGAACAGGTGGCGATCAT

Product: phosphonate-binding periplasmic protein

Products: 3-phospho-serine [Cytoplasm]; phosphate [Cytoplasm]; alkylphosphonate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MLKRTLALTAGLALSLSAVLAQAAEVLKVSAIPDEAPTELLRKFEPLGKYLQQQLGMDVQFVPVADYPAVVEALATDRLD
LAWLGGFTFVQARLKTGNAIPLVQREQDAQFTSKFITADPNVKSLADLKGKTFAFGSVSSTSGSLMPRYFMLKDGIKPES
YFSRVGYSGAHDATVAWVQAGKVDAGVLNASVWQKLVDAGKVDTNKVKVFATTPTYFDYNWTVRGTLDPALAAKIKKAFL
DLDPANPEHKKILDLQAASRFIETSPDNYKGIEEAARAADLLK

Sequences:

>Translated_283_residues
MLKRTLALTAGLALSLSAVLAQAAEVLKVSAIPDEAPTELLRKFEPLGKYLQQQLGMDVQFVPVADYPAVVEALATDRLD
LAWLGGFTFVQARLKTGNAIPLVQREQDAQFTSKFITADPNVKSLADLKGKTFAFGSVSSTSGSLMPRYFMLKDGIKPES
YFSRVGYSGAHDATVAWVQAGKVDAGVLNASVWQKLVDAGKVDTNKVKVFATTPTYFDYNWTVRGTLDPALAAKIKKAFL
DLDPANPEHKKILDLQAASRFIETSPDNYKGIEEAARAADLLK
>Mature_283_residues
MLKRTLALTAGLALSLSAVLAQAAEVLKVSAIPDEAPTELLRKFEPLGKYLQQQLGMDVQFVPVADYPAVVEALATDRLD
LAWLGGFTFVQARLKTGNAIPLVQREQDAQFTSKFITADPNVKSLADLKGKTFAFGSVSSTSGSLMPRYFMLKDGIKPES
YFSRVGYSGAHDATVAWVQAGKVDAGVLNASVWQKLVDAGKVDTNKVKVFATTPTYFDYNWTVRGTLDPALAAKIKKAFL
DLDPANPEHKKILDLQAASRFIETSPDNYKGIEEAARAADLLK

Specific function: Probably forms part of a binding-protein-dependent phosphite transporter. Required for oxidation of phosphite to phosphate [H]

COG id: COG3221

COG function: function code P; ABC-type phosphate/phosphonate transport system, periplasmic component

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790543, Length=260, Percent_Identity=24.2307692307692, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015168
- InterPro:   IPR005770 [H]

Pfam domain/function: PF09084 NMT1 [H]

EC number: NA

Molecular weight: Translated: 30731; Mature: 30731

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKRTLALTAGLALSLSAVLAQAAEVLKVSAIPDEAPTELLRKFEPLGKYLQQQLGMDVQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEE
FVPVADYPAVVEALATDRLDLAWLGGFTFVQARLKTGNAIPLVQREQDAQFTSKFITADP
EEECCCCHHHHHHHHHCCCCEEECCHHHHHHHHHCCCCCCCEEECCCHHHHHHHHCCCCC
NVKSLADLKGKTFAFGSVSSTSGSLMPRYFMLKDGIKPESYFSRVGYSGAHDATVAWVQA
CHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHCCCCHHHHHHHCCCCCCCCCEEEEEEC
GKVDAGVLNASVWQKLVDAGKVDTNKVKVFATTPTYFDYNWTVRGTLDPALAAKIKKAFL
CCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEECCEEEECCCCHHHHHHHHHHHH
DLDPANPEHKKILDLQAASRFIETSPDNYKGIEEAARAADLLK
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MLKRTLALTAGLALSLSAVLAQAAEVLKVSAIPDEAPTELLRKFEPLGKYLQQQLGMDVQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEE
FVPVADYPAVVEALATDRLDLAWLGGFTFVQARLKTGNAIPLVQREQDAQFTSKFITADP
EEECCCCHHHHHHHHHCCCCEEECCHHHHHHHHHCCCCCCCEEECCCHHHHHHHHCCCCC
NVKSLADLKGKTFAFGSVSSTSGSLMPRYFMLKDGIKPESYFSRVGYSGAHDATVAWVQA
CHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHCCCCHHHHHHHCCCCCCCCCEEEEEEC
GKVDAGVLNASVWQKLVDAGKVDTNKVKVFATTPTYFDYNWTVRGTLDPALAAKIKKAFL
CCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEECCEEEECCCCHHHHHHHHHHHH
DLDPANPEHKKILDLQAASRFIETSPDNYKGIEEAARAADLLK
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 3-phospho-serine [Periplasm]; phosphite [Periplasm]; H2O; phosphate [Periplasm]; alkylphosphonate [Periplasm] [C]

Specific reaction: H2O + ATP + 3-phospho-serine [Periplasm] = ADP + phosphate + 3-phospho-serine [Cytoplasm] ATP + phosphite [Periplasm] + H2O = phosphite [Cytoplasm] + ADP + phosphate phosphate [Periplasm] + ATP + H2O = ADP + phosphate [Cytoplasm] + phosphate [Cytoplasm] A

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9791102 [H]