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The map label for this gene is thcR [H]

Identifier: 77458605

GI number: 77458605

Start: 2736378

End: 2737346

Strand: Reverse

Name: thcR [H]

Synonym: Pfl01_2378

Alternate gene names: 77458605

Gene position: 2737346-2736378 (Counterclockwise)

Preceding gene: 77458606

Following gene: 77458603

Centisome position: 42.52

GC content: 60.99

Gene sequence:

>969_bases
GTGTACTCAAGCCCGACGCGCCAGACCCTCATCCTGCGATCCGACAACATGGCCAGCGACGACTTCGGTGCCCTGTTCTC
GCGAATGTTCGGCAACCGTTATGGCGATACCCCGCCGCCGCCAAAAGACATCATCATCGGCGGCGTTTACGGACGGTATG
AAGGCGTGAGTTTCCGGCGCATGCATTACCGGGGCGATTTCACCGTTGCCTTCCCCGAGCCGTTCGACGAAATCACTTTC
GTCATTCCCACCGCCGGCAAGATCGTTTTCAACCATGAATCCGTGGGGCTGAGCGATGTGGGGCTGGCCATCGACAAGGC
TGACCTGCGTTCGATGCGTTTTATCGACAATCATGCCCAGCACGGCATGTCGATCAGCCGTGCGGCGCTCACCGAACGGC
TGTCGACCCTGCTGGGCAAACCGATCGTGCACAAGCTGCATTTCGAGCCGAGGGTGGATCTGAACAGCCCGGCGTGTCAG
GGCATTCGCGCGCTGATCGATCTGGCCACCGGTGCGGAATTCGATCTGCTGTTGAACGCTGGCTCGCTGATGCCGTCACG
GCTGCGGGAGATGCTGGTGGACGCGGTATTGGAAGCCTGGCCGCACAATTTCAGCCAGGCCTTGCGCCGTCCAGAGGCAT
TGATTGCGCCCAGGCATGTGCGGCAGGCGATCGATTACATTCAGGCGCATCCCGAGATTCAGATCAGTGGCACGGATCTG
GCGCGGCTGGCCAACGTCAGCCTGCGCGCATTGCAGGAAGGGTTTCGACGGTTTGCCGGGATGTCGATTGTCGGGTATCA
GCGGCAGGTGCGGCTGGAGCGCGCTTACGAAACGTTGCGTCAGGGCGTTTCGCCGTCGGTGACTGAGGTGGCGCTGCGAT
TGGGCTTCAGCAATGTCGGCCGGTTCAGCCAGTATTTCCAGAATGCCTACGGCGTGAGCCCGGCCGAGGTTCGAAAAGGA
TTGCGCTGA

Upstream 100 bases:

>100_bases
TGGCGTTCACGCACAGCATCGAACGTTGTCACATCGGCGTCATTCTCCCTTGGTAACGTCGTCGCGCCCCGATGCCCCGA
CCACCAAGGTGACCCTCCCG

Downstream 100 bases:

>100_bases
GGCAATCCTTTTCCTTCACCTTCAGTTGATCAGAACTGGTAACTGGCCTTGAGCCCGCCGCTGAAACCATGGCTGTCGCC
GCCACCGCTGGCACCGACTT

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MYSSPTRQTLILRSDNMASDDFGALFSRMFGNRYGDTPPPPKDIIIGGVYGRYEGVSFRRMHYRGDFTVAFPEPFDEITF
VIPTAGKIVFNHESVGLSDVGLAIDKADLRSMRFIDNHAQHGMSISRAALTERLSTLLGKPIVHKLHFEPRVDLNSPACQ
GIRALIDLATGAEFDLLLNAGSLMPSRLREMLVDAVLEAWPHNFSQALRRPEALIAPRHVRQAIDYIQAHPEIQISGTDL
ARLANVSLRALQEGFRRFAGMSIVGYQRQVRLERAYETLRQGVSPSVTEVALRLGFSNVGRFSQYFQNAYGVSPAEVRKG
LR

Sequences:

>Translated_322_residues
MYSSPTRQTLILRSDNMASDDFGALFSRMFGNRYGDTPPPPKDIIIGGVYGRYEGVSFRRMHYRGDFTVAFPEPFDEITF
VIPTAGKIVFNHESVGLSDVGLAIDKADLRSMRFIDNHAQHGMSISRAALTERLSTLLGKPIVHKLHFEPRVDLNSPACQ
GIRALIDLATGAEFDLLLNAGSLMPSRLREMLVDAVLEAWPHNFSQALRRPEALIAPRHVRQAIDYIQAHPEIQISGTDL
ARLANVSLRALQEGFRRFAGMSIVGYQRQVRLERAYETLRQGVSPSVTEVALRLGFSNVGRFSQYFQNAYGVSPAEVRKG
LR
>Mature_322_residues
MYSSPTRQTLILRSDNMASDDFGALFSRMFGNRYGDTPPPPKDIIIGGVYGRYEGVSFRRMHYRGDFTVAFPEPFDEITF
VIPTAGKIVFNHESVGLSDVGLAIDKADLRSMRFIDNHAQHGMSISRAALTERLSTLLGKPIVHKLHFEPRVDLNSPACQ
GIRALIDLATGAEFDLLLNAGSLMPSRLREMLVDAVLEAWPHNFSQALRRPEALIAPRHVRQAIDYIQAHPEIQISGTDL
ARLANVSLRALQEGFRRFAGMSIVGYQRQVRLERAYETLRQGVSPSVTEVALRLGFSNVGRFSQYFQNAYGVSPAEVRKG
LR

Specific function: Probably involved in the positive regulation of the thc operon for the degradation of the thiocarbamate herbicide EPTC [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 35992; Mature: 35992

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSSPTRQTLILRSDNMASDDFGALFSRMFGNRYGDTPPPPKDIIIGGVYGRYEGVSFRR
CCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCEEEE
MHYRGDFTVAFPEPFDEITFVIPTAGKIVFNHESVGLSDVGLAIDKADLRSMRFIDNHAQ
EEECCCEEEECCCCCCCEEEEEECCCEEEEECCCCCCHHHHHEECHHHHHHHHHHHHHHH
HGMSISRAALTERLSTLLGKPIVHKLHFEPRVDLNSPACQGIRALIDLATGAEFDLLLNA
HCCHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEC
GSLMPSRLREMLVDAVLEAWPHNFSQALRRPEALIAPRHVRQAIDYIQAHPEIQISGTDL
CCCCHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHCCHHHHHHHHHHHHCCCCEEECCCHH
ARLANVSLRALQEGFRRFAGMSIVGYQRQVRLERAYETLRQGVSPSVTEVALRLGFSNVG
HHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCHHHHH
RFSQYFQNAYGVSPAEVRKGLR
HHHHHHHHHCCCCHHHHHCCCC
>Mature Secondary Structure
MYSSPTRQTLILRSDNMASDDFGALFSRMFGNRYGDTPPPPKDIIIGGVYGRYEGVSFRR
CCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCEEEE
MHYRGDFTVAFPEPFDEITFVIPTAGKIVFNHESVGLSDVGLAIDKADLRSMRFIDNHAQ
EEECCCEEEECCCCCCCEEEEEECCCEEEEECCCCCCHHHHHEECHHHHHHHHHHHHHHH
HGMSISRAALTERLSTLLGKPIVHKLHFEPRVDLNSPACQGIRALIDLATGAEFDLLLNA
HCCHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEC
GSLMPSRLREMLVDAVLEAWPHNFSQALRRPEALIAPRHVRQAIDYIQAHPEIQISGTDL
CCCCHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHCCHHHHHHHHHHHHCCCCEEECCCHH
ARLANVSLRALQEGFRRFAGMSIVGYQRQVRLERAYETLRQGVSPSVTEVALRLGFSNVG
HHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCHHHHH
RFSQYFQNAYGVSPAEVRKGLR
HHHHHHHHHCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7836301 [H]