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The map label for this gene is pcbC [H]

Identifier: 77458561

GI number: 77458561

Start: 2693499

End: 2694551

Strand: Direct

Name: pcbC [H]

Synonym: Pfl01_2334

Alternate gene names: 77458561

Gene position: 2693499-2694551 (Clockwise)

Preceding gene: 77458560

Following gene: 77458562

Centisome position: 41.83

GC content: 62.96

Gene sequence:

>1053_bases
ATGCCGCACACCTCAAAGATCACCGCATTACCCATCCTCGACCTGTCCCTGCTCGACGGCACGCCGTCGCAACGCCAGGC
CTTTCTTGATGACCTGCGCCATGCTGCCCGCGATGTGGGTTTTTTCTACCTGACCGGCCATGGCATCGACGCCGGCCTGC
TCGAGCAAGTGCAGGACTACGCACGCCAGTTCTTCGCCTTGCCCGACAGCGAGAAAAACGCCGTCGGCATGATCAATTCG
CCGCACTTTCGCGGCTACAACCGCGCCGCTTCCGAGATCACCCGTGGCCAGCCCGATCAGCGTGAGCAATTCGATCTGGG
CGCCGAGCGCGACGTCTTGCCGTTGAACGCTGACAGTCCGTTATGGGCGCGGCTGCAAGGGCCGAATCAATGGCCCGGAG
CGTTGCCGCAACTCAAGCCGCTGTTGCTCGACTGGCAGCAGGCGATGACCCAAATGTCGCTGCGCCTGCTGCGCGCATTC
GCTCAGGCGCTGTCCTTGCCGGAAGACGCTTTCGACCGGTTGTACGGCGACAAACCCAACGAACACATCAAGCTGATGCG
CTATCCGGGGCAAGCCTCGACCGCGAGCAATCAGGGCGTCGGTGCGCACAAGGATTCGGGTTTTCTCAGCTTCCTGCTGC
AAGACCAGCAGGCCGGGCTGCAAGTGGAGATCGAAGAGGGGCGCTGGATCGATGCGCTGCCTCGGGACAATACGCTGGTG
GTGAACATCGGCGAGCTGCTGGAGCTGGCCACCAACGGTTATCTGCGCGCCACGGTGCATCGGGTGGTGTCGCCACCAGT
GGGCAGCGAGCGATTGTCCATCGCGTTTTTCCTCGGCGCGCAACTGGATGCGGTAGTGCCGCTGTACCCCTTGCCGACGG
CGCTGTTGCGTGAGGCGCGTGGCCCGGCGAGTGATCCGCTCAATCCGCTGTTTCGCGATGTCGGCTGGAATTACCTGAAG
GGCCGACTGCGCTCCCATCCCGATGTCGCGCAGCGTTTTTATGCCGATGCGTCGAATACCAGCACACCGCTGCGCAAGAC
CGCCAACGCCTGA

Upstream 100 bases:

>100_bases
ACGAATCAAAAGCATCAAACCGACAGACCCCCGATTGCCATGACGGCACACGCTGAATCGATCACAGGCTCTTCAGGTTT
GATTCACACGGGAGTGAATC

Downstream 100 bases:

>100_bases
TCCATCACTCGCAGAAGGACTCTTTCCATGTTGAAAAAAGCAGGCTTGACCCTGGCCGTCCTCGGCGCGCTGGTGACTTC
GTTCAGTGCCCAGGCGCTCG

Product: 2OG-Fe(II) oxygenase

Products: NA

Alternate protein names: IPNS [H]

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MPHTSKITALPILDLSLLDGTPSQRQAFLDDLRHAARDVGFFYLTGHGIDAGLLEQVQDYARQFFALPDSEKNAVGMINS
PHFRGYNRAASEITRGQPDQREQFDLGAERDVLPLNADSPLWARLQGPNQWPGALPQLKPLLLDWQQAMTQMSLRLLRAF
AQALSLPEDAFDRLYGDKPNEHIKLMRYPGQASTASNQGVGAHKDSGFLSFLLQDQQAGLQVEIEEGRWIDALPRDNTLV
VNIGELLELATNGYLRATVHRVVSPPVGSERLSIAFFLGAQLDAVVPLYPLPTALLREARGPASDPLNPLFRDVGWNYLK
GRLRSHPDVAQRFYADASNTSTPLRKTANA

Sequences:

>Translated_350_residues
MPHTSKITALPILDLSLLDGTPSQRQAFLDDLRHAARDVGFFYLTGHGIDAGLLEQVQDYARQFFALPDSEKNAVGMINS
PHFRGYNRAASEITRGQPDQREQFDLGAERDVLPLNADSPLWARLQGPNQWPGALPQLKPLLLDWQQAMTQMSLRLLRAF
AQALSLPEDAFDRLYGDKPNEHIKLMRYPGQASTASNQGVGAHKDSGFLSFLLQDQQAGLQVEIEEGRWIDALPRDNTLV
VNIGELLELATNGYLRATVHRVVSPPVGSERLSIAFFLGAQLDAVVPLYPLPTALLREARGPASDPLNPLFRDVGWNYLK
GRLRSHPDVAQRFYADASNTSTPLRKTANA
>Mature_349_residues
PHTSKITALPILDLSLLDGTPSQRQAFLDDLRHAARDVGFFYLTGHGIDAGLLEQVQDYARQFFALPDSEKNAVGMINSP
HFRGYNRAASEITRGQPDQREQFDLGAERDVLPLNADSPLWARLQGPNQWPGALPQLKPLLLDWQQAMTQMSLRLLRAFA
QALSLPEDAFDRLYGDKPNEHIKLMRYPGQASTASNQGVGAHKDSGFLSFLLQDQQAGLQVEIEEGRWIDALPRDNTLVV
NIGELLELATNGYLRATVHRVVSPPVGSERLSIAFFLGAQLDAVVPLYPLPTALLREARGPASDPLNPLFRDVGWNYLKG
RLRSHPDVAQRFYADASNTSTPLRKTANA

Specific function: Removes, in the presence of oxygen, 4 hydrogen atoms from delta-L-(alpha-aminoadipyl)-L-cysteinyl-D-valine (ACV) to form the azetidinone and thiazolidine rings of isopenicillin [H]

COG id: COG3491

COG function: function code R; Isopenicillin N synthase and related dioxygenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe2OG dioxygenase domain [H]

Homologues:

Organism=Drosophila melanogaster, GI28572124, Length=321, Percent_Identity=25.8566978193146, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002057
- InterPro:   IPR002283
- InterPro:   IPR005123 [H]

Pfam domain/function: PF03171 2OG-FeII_Oxy [H]

EC number: =1.21.3.1 [H]

Molecular weight: Translated: 38808; Mature: 38677

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHTSKITALPILDLSLLDGTPSQRQAFLDDLRHAARDVGFFYLTGHGIDAGLLEQVQDY
CCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHH
ARQFFALPDSEKNAVGMINSPHFRGYNRAASEITRGQPDQREQFDLGAERDVLPLNADSP
HHHHHCCCCCCCCCEECCCCCCCCCCHHHHHHHHCCCCCCHHHHCCCCCCCEEECCCCCC
LWARLQGPNQWPGALPQLKPLLLDWQQAMTQMSLRLLRAFAQALSLPEDAFDRLYGDKPN
CEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCC
EHIKLMRYPGQASTASNQGVGAHKDSGFLSFLLQDQQAGLQVEIEEGRWIDALPRDNTLV
CCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCEEECCCCCCEEE
VNIGELLELATNGYLRATVHRVVSPPVGSERLSIAFFLGAQLDAVVPLYPLPTALLREAR
EEHHHHHHHHHCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHCC
GPASDPLNPLFRDVGWNYLKGRLRSHPDVAQRFYADASNTSTPLRKTANA
CCCCCCHHHHHHHCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCCHHCCCC
>Mature Secondary Structure 
PHTSKITALPILDLSLLDGTPSQRQAFLDDLRHAARDVGFFYLTGHGIDAGLLEQVQDY
CCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHH
ARQFFALPDSEKNAVGMINSPHFRGYNRAASEITRGQPDQREQFDLGAERDVLPLNADSP
HHHHHCCCCCCCCCEECCCCCCCCCCHHHHHHHHCCCCCCHHHHCCCCCCCEEECCCCCC
LWARLQGPNQWPGALPQLKPLLLDWQQAMTQMSLRLLRAFAQALSLPEDAFDRLYGDKPN
CEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCC
EHIKLMRYPGQASTASNQGVGAHKDSGFLSFLLQDQQAGLQVEIEEGRWIDALPRDNTLV
CCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCEEECCCCCCEEE
VNIGELLELATNGYLRATVHRVVSPPVGSERLSIAFFLGAQLDAVVPLYPLPTALLREAR
EEHHHHHHHHHCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHCC
GPASDPLNPLFRDVGWNYLKGRLRSHPDVAQRFYADASNTSTPLRKTANA
CCCCCCHHHHHHHCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3130293 [H]