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The map label for this gene is xylH [H]

Identifier: 77458527

GI number: 77458527

Start: 2651529

End: 2652665

Strand: Reverse

Name: xylH [H]

Synonym: Pfl01_2300

Alternate gene names: 77458527

Gene position: 2652665-2651529 (Counterclockwise)

Preceding gene: 77458528

Following gene: 77458526

Centisome position: 41.2

GC content: 62.97

Gene sequence:

>1137_bases
ATGAATCAGGTCAAACAACTCTTCACCCGCTACAAGATGCTCGCACTGGTGTTTGCCGTGGCGTTGATCTGGCTGTTCTT
CAGCTGGCAGACCGAGGGCGGATTCCTGACACCACGCAACCTCTCCAACCTGCTGCGCCAGATGTCCATCACCGGGATCC
TCGCCTGCGGCATGGTGCTGGTCATCATCAGCGGCGAGATCGATCTGTCCGTCGGCTCATTGCTGGGCCTGCTCGGTGGC
GTGGCAGCCATTCTCGACGTTGTCTATCACATACCACTGCTGGCGAACCTGAGCCTTGTGGTGGTGTGCGGACTGCTGAT
CGGCCTCGCCAACGGCTACATGGCGGCCTACCTGCGCATTCCGTCGTTCATCGTGGGGCTGGGAGGCATGCTGGCTTTTC
GGGGGATTTTGCTGGGGATCACCGGCGGCACGACCATTGCGCCGGTGTCGCCGGAACTCGTCTACATTGGCCAGGGTTAT
CTGCCCCATACGGTCGGCGCGGGTCTGGGTGTCCTGCTGTTCGCACTGACGTTGTTCCTGACCTGGAAACAACGGCGCAA
TCGCGCCCTTCACGGCCTCGCGGCACATTCACTGGCGCGTGACGTGGCACGCGTGTTGCTGATCGGCGCGGTGCTGGCCG
GGTTTGTCCAGACCCTCAACAGCTATGACGGCATTCCCGTGCCGGTCCTGCTCCTGCTGATCCTGCTGGGCGGATTCAGC
TATGTGACCAGCCAGACCGTGTTCGGCCGACGCGTCTATTCCGTGGGCAGCAACATGGAAGCGACGCGCCTGTCCGGTAT
CAATGTGCAGGCCGTGAAGCTCTGGATCTTCGGGATCATGGGCGTGATGTGCGCCCTCGCCGGCGTGGTCAACACCGCGC
GCCTGGCCGCCGGCTCCCCCTCGGCCGGCAGCATGGGCGAACTCGACGCCATCGCCGCCTGCTTCATCGGTGGCACCTCG
ATGCGTGGCGGTTCCGGCACAGTCTATGGCGCCCTCCTCGGCGCCCTGGTCATCACCAGCCTGGACAACGGCATGTCCAT
GCTCGACGTCGACAGCTACTGGCAGATGATCGTCAAGGGCAGCATTCTGGTGTTGGCGGTTTGGGTTGATGTGAGTACGC
GGACTGGGCGGCGTTGA

Upstream 100 bases:

>100_bases
GGGCGATTTCGTCAACCATGAACTCACTCAGGAACAGGTACTCGCCGCCGCACTCAGCCAGCCTGACAGCCATAACAATA
AAGATCGGAAATCCGCGTAA

Downstream 100 bases:

>100_bases
CAGGCTGCTGTCATCCCAGGCCTTTATCCGAAGCAGTCCAAAGCCTAAATTGGCGTCCATGGCACTGGATCACGCCAGTG
TAATTTCATCGATAACCGAG

Product: inner-membrane translocator

Products: ADP; phosphate; xylose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MNQVKQLFTRYKMLALVFAVALIWLFFSWQTEGGFLTPRNLSNLLRQMSITGILACGMVLVIISGEIDLSVGSLLGLLGG
VAAILDVVYHIPLLANLSLVVVCGLLIGLANGYMAAYLRIPSFIVGLGGMLAFRGILLGITGGTTIAPVSPELVYIGQGY
LPHTVGAGLGVLLFALTLFLTWKQRRNRALHGLAAHSLARDVARVLLIGAVLAGFVQTLNSYDGIPVPVLLLLILLGGFS
YVTSQTVFGRRVYSVGSNMEATRLSGINVQAVKLWIFGIMGVMCALAGVVNTARLAAGSPSAGSMGELDAIAACFIGGTS
MRGGSGTVYGALLGALVITSLDNGMSMLDVDSYWQMIVKGSILVLAVWVDVSTRTGRR

Sequences:

>Translated_378_residues
MNQVKQLFTRYKMLALVFAVALIWLFFSWQTEGGFLTPRNLSNLLRQMSITGILACGMVLVIISGEIDLSVGSLLGLLGG
VAAILDVVYHIPLLANLSLVVVCGLLIGLANGYMAAYLRIPSFIVGLGGMLAFRGILLGITGGTTIAPVSPELVYIGQGY
LPHTVGAGLGVLLFALTLFLTWKQRRNRALHGLAAHSLARDVARVLLIGAVLAGFVQTLNSYDGIPVPVLLLLILLGGFS
YVTSQTVFGRRVYSVGSNMEATRLSGINVQAVKLWIFGIMGVMCALAGVVNTARLAAGSPSAGSMGELDAIAACFIGGTS
MRGGSGTVYGALLGALVITSLDNGMSMLDVDSYWQMIVKGSILVLAVWVDVSTRTGRR
>Mature_378_residues
MNQVKQLFTRYKMLALVFAVALIWLFFSWQTEGGFLTPRNLSNLLRQMSITGILACGMVLVIISGEIDLSVGSLLGLLGG
VAAILDVVYHIPLLANLSLVVVCGLLIGLANGYMAAYLRIPSFIVGLGGMLAFRGILLGITGGTTIAPVSPELVYIGQGY
LPHTVGAGLGVLLFALTLFLTWKQRRNRALHGLAAHSLARDVARVLLIGAVLAGFVQTLNSYDGIPVPVLLLLILLGGFS
YVTSQTVFGRRVYSVGSNMEATRLSGINVQAVKLWIFGIMGVMCALAGVVNTARLAAGSPSAGSMGELDAIAACFIGGTS
MRGGSGTVYGALLGALVITSLDNGMSMLDVDSYWQMIVKGSILVLAVWVDVSTRTGRR

Specific function: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4214

COG function: function code G; ABC-type xylose transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789992, Length=363, Percent_Identity=53.4435261707989, Blast_Score=336, Evalue=1e-93,
Organism=Escherichia coli, GI1790191, Length=147, Percent_Identity=46.2585034013605, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1788896, Length=151, Percent_Identity=40.3973509933775, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1790524, Length=147, Percent_Identity=42.1768707482993, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI145693152, Length=205, Percent_Identity=30.2439024390244, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1787793, Length=336, Percent_Identity=27.9761904761905, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788471, Length=135, Percent_Identity=39.2592592592593, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI145693214, Length=152, Percent_Identity=35.5263157894737, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI87082395, Length=129, Percent_Identity=34.8837209302326, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 39826; Mature: 39826

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQVKQLFTRYKMLALVFAVALIWLFFSWQTEGGFLTPRNLSNLLRQMSITGILACGMVL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VIISGEIDLSVGSLLGLLGGVAAILDVVYHIPLLANLSLVVVCGLLIGLANGYMAAYLRI
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PSFIVGLGGMLAFRGILLGITGGTTIAPVSPELVYIGQGYLPHTVGAGLGVLLFALTLFL
HHHHHHHHHHHHHHHHHEEECCCCEECCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHH
TWKQRRNRALHGLAAHSLARDVARVLLIGAVLAGFVQTLNSYDGIPVPVLLLLILLGGFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHH
YVTSQTVFGRRVYSVGSNMEATRLSGINVQAVKLWIFGIMGVMCALAGVVNTARLAAGSP
HHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SAGSMGELDAIAACFIGGTSMRGGSGTVYGALLGALVITSLDNGMSMLDVDSYWQMIVKG
CCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHCC
SILVLAVWVDVSTRTGRR
CEEEEEEEEECCCCCCCC
>Mature Secondary Structure
MNQVKQLFTRYKMLALVFAVALIWLFFSWQTEGGFLTPRNLSNLLRQMSITGILACGMVL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VIISGEIDLSVGSLLGLLGGVAAILDVVYHIPLLANLSLVVVCGLLIGLANGYMAAYLRI
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PSFIVGLGGMLAFRGILLGITGGTTIAPVSPELVYIGQGYLPHTVGAGLGVLLFALTLFL
HHHHHHHHHHHHHHHHHEEECCCCEECCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHH
TWKQRRNRALHGLAAHSLARDVARVLLIGAVLAGFVQTLNSYDGIPVPVLLLLILLGGFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHH
YVTSQTVFGRRVYSVGSNMEATRLSGINVQAVKLWIFGIMGVMCALAGVVNTARLAAGSP
HHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SAGSMGELDAIAACFIGGTSMRGGSGTVYGALLGALVITSLDNGMSMLDVDSYWQMIVKG
CCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHCC
SILVLAVWVDVSTRTGRR
CEEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; xylose [Periplasm]; H2O [C]

Specific reaction: ATP + xylose [Periplasm] + H2O = ADP + phosphate + xylose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]