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The map label for this gene is lysR [H]

Identifier: 77458417

GI number: 77458417

Start: 2474402

End: 2475295

Strand: Reverse

Name: lysR [H]

Synonym: Pfl01_2190

Alternate gene names: 77458417

Gene position: 2475295-2474402 (Counterclockwise)

Preceding gene: 77458418

Following gene: 77458411

Centisome position: 38.45

GC content: 65.44

Gene sequence:

>894_bases
ATGCGTTTACGTCATATCGAAGTGATTCAGGCGCTTTTGCAGACCGGTCACGTGGGCACCGCCGCCGAATGGCTGCAACT
CCCGGCGCCCGAGGTCGAGGAGCGTTTGCGCGAAGCCGAGAGTCAGCTTGGTTTCATGCTGTTCGCCAGCGTACGCGGAC
GACTTCAGCCAACTCCGGAGGCCCGGGCGCTGCAAGTCGAGATCGGCCACATCTATGAAGCGCTGGAACCGGTGCAACGG
CTGGCCAGCAGCCTCAAGCAATACCTCGCCCCGCCCCTGCGGATCATCGGCACCCCGCCGCTGGCCCAGCAACTGCTTCC
GCAAAGCCTCGCCGCCCTGCGCCGTTGCTTGCCCGACGTGCCCTGCACCCTGCTCAGCGAACCGACCCGTGACATTGTCC
GCCACCTGCTGCTGCGCGACAGCGATCTGGGCCTGAGCCTGCACGACCCACAACACCCCGACATTGATTGCCAGCCGCTG
GCCCAGGGCAAATTGCAATTGCTCGCGCCCCACGGCTGGCTGCAACCGAAGCAGAAATACATTTCCCTGCAGGATCTGGC
CGGCCAGGCGATGGTCGGCCTCGAAGGCCAGGACCCGCTGAGTCCGGCCCTGGAAAACAAGCTCCAGGCCCTGCGCCCGG
CGCCGACCATCCAGACCCGCGTACAAACCCACCAGATGATGCGCAGCATGGTCGAGGCCGGCGAAGGCCTGGCGATCGTC
GATCCGTTCACCGCCCTCGGTGCACGGGCGGGCGGTCTCGATGTCTGCCCACTGTCGCCGGCGGTGCCGATCAGCCTCTA
TGCCCTGACCTTCAAACACGCCACGCCGTCAGCGGCGATTCAGACGCTGCTCGGTATCGTCACGGAACAAGCCGAGGCGA
TGCTGGCGAACTGA

Upstream 100 bases:

>100_bases
TCGGTCGCTTCATAACCGATCGTTATGAGCAGAAGTCATCCGCGCCGAGTTGGGGTAGGATTCAGCCACTGACCCCAACG
GCCGGACATGGACTTCACGC

Downstream 100 bases:

>100_bases
TCGGATGCTCCAGCGGATTATCGAACAATCGATACCAGAACAACGCCACTTCGGCGGTGTTCGGATCGATGCCGCGATAA
CGCAGATGGTCGATGCCGCC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MRLRHIEVIQALLQTGHVGTAAEWLQLPAPEVEERLREAESQLGFMLFASVRGRLQPTPEARALQVEIGHIYEALEPVQR
LASSLKQYLAPPLRIIGTPPLAQQLLPQSLAALRRCLPDVPCTLLSEPTRDIVRHLLLRDSDLGLSLHDPQHPDIDCQPL
AQGKLQLLAPHGWLQPKQKYISLQDLAGQAMVGLEGQDPLSPALENKLQALRPAPTIQTRVQTHQMMRSMVEAGEGLAIV
DPFTALGARAGGLDVCPLSPAVPISLYALTFKHATPSAAIQTLLGIVTEQAEAMLAN

Sequences:

>Translated_297_residues
MRLRHIEVIQALLQTGHVGTAAEWLQLPAPEVEERLREAESQLGFMLFASVRGRLQPTPEARALQVEIGHIYEALEPVQR
LASSLKQYLAPPLRIIGTPPLAQQLLPQSLAALRRCLPDVPCTLLSEPTRDIVRHLLLRDSDLGLSLHDPQHPDIDCQPL
AQGKLQLLAPHGWLQPKQKYISLQDLAGQAMVGLEGQDPLSPALENKLQALRPAPTIQTRVQTHQMMRSMVEAGEGLAIV
DPFTALGARAGGLDVCPLSPAVPISLYALTFKHATPSAAIQTLLGIVTEQAEAMLAN
>Mature_297_residues
MRLRHIEVIQALLQTGHVGTAAEWLQLPAPEVEERLREAESQLGFMLFASVRGRLQPTPEARALQVEIGHIYEALEPVQR
LASSLKQYLAPPLRIIGTPPLAQQLLPQSLAALRRCLPDVPCTLLSEPTRDIVRHLLLRDSDLGLSLHDPQHPDIDCQPL
AQGKLQLLAPHGWLQPKQKYISLQDLAGQAMVGLEGQDPLSPALENKLQALRPAPTIQTRVQTHQMMRSMVEAGEGLAIV
DPFTALGARAGGLDVCPLSPAVPISLYALTFKHATPSAAIQTLLGIVTEQAEAMLAN

Specific function: This protein activates the transcription of the lysA gene encoding diaminopimelate decarboxylase. LysR is also a negative regulator of its own expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789204, Length=287, Percent_Identity=28.9198606271777, Blast_Score=99, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32357; Mature: 32357

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLRHIEVIQALLQTGHVGTAAEWLQLPAPEVEERLREAESQLGFMLFASVRGRLQPTPE
CCCHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
ARALQVEIGHIYEALEPVQRLASSLKQYLAPPLRIIGTPPLAQQLLPQSLAALRRCLPDV
CEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHHCCCC
PCTLLSEPTRDIVRHLLLRDSDLGLSLHDPQHPDIDCQPLAQGKLQLLAPHGWLQPKQKY
CHHHHCCCHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHH
ISLQDLAGQAMVGLEGQDPLSPALENKLQALRPAPTIQTRVQTHQMMRSMVEAGEGLAIV
HHHHHHCCCCEECCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEE
DPFTALGARAGGLDVCPLSPAVPISLYALTFKHATPSAAIQTLLGIVTEQAEAMLAN
CCHHHHCCCCCCCCCCCCCCCCCHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRLRHIEVIQALLQTGHVGTAAEWLQLPAPEVEERLREAESQLGFMLFASVRGRLQPTPE
CCCHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
ARALQVEIGHIYEALEPVQRLASSLKQYLAPPLRIIGTPPLAQQLLPQSLAALRRCLPDV
CEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHHCCCC
PCTLLSEPTRDIVRHLLLRDSDLGLSLHDPQHPDIDCQPLAQGKLQLLAPHGWLQPKQKY
CHHHHCCCHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHH
ISLQDLAGQAMVGLEGQDPLSPALENKLQALRPAPTIQTRVQTHQMMRSMVEAGEGLAIV
HHHHHHCCCCEECCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEE
DPFTALGARAGGLDVCPLSPAVPISLYALTFKHATPSAAIQTLLGIVTEQAEAMLAN
CCHHHHCCCCCCCCCCCCCCCCCHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6350602; 9278503; 2836407 [H]