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The map label for this gene is yfjP [H]

Identifier: 77458383

GI number: 77458383

Start: 2439190

End: 2439816

Strand: Reverse

Name: yfjP [H]

Synonym: Pfl01_2156

Alternate gene names: 77458383

Gene position: 2439816-2439190 (Counterclockwise)

Preceding gene: 77458384

Following gene: 77458379

Centisome position: 37.89

GC content: 63.48

Gene sequence:

>627_bases
ATGCCCGATCCCTACCAACCGGCCAGCGAGTTTCTGGCCAGCCTCGATGCCGACTGGCAGCGCCACATTGCTGCGGTCGG
TCCCTGCCTGCATCAGCCGCATCCGACGCGCGATCCGTATGAATCGCTGGTGCGGGCGATTGCCTATCAGCAACTGCACG
CCAAGGCTGGCGATGCGATTGTCGGGCGGCTGGTGGGGTTGTTTCCCGGGCAGACGTTTCCGCGTCCGGAGCAGATTCTG
GCGACGGACTTCGATCAATTGCGCGGTTGCGGGTTTTCGGCGGGCAAGATTGCGACGATTCAGGGGATTGCCCAGGCGAC
CCTGGACGGTGTGGTGCCGGATTACCCTACCGCGCTGGCGATGGAGGATGAGGCGCTGATCGAGCGGTTGGTCAGCCTGC
GCGGGGTTGGGCGCTGGACGGTGGAGATGTTGCTGATCTACAGCCTGGAGCGGCCGGATATTCTGCCGGCCGACGATTTC
GGAGTGCGCGAAGGGTATCGGCGGTTGAAGGGGCTGGAGGTGCAGCCTGCGCGCAAACAAATGATTGAGATCGGGTTGGA
TTGGAAGCCGTTTCGGACGGTGGCGGCCTGGTATTTGTGGCGGGTGCCGAAAAGCCCCTCACCCTAG

Upstream 100 bases:

>100_bases
GGGCTCACTGGTGAAAAGTTTTCTCGCCAGCGGCAAGCTCGACACCCATGACCTCAAGGCCTTCACCTATGGCGAAGTCA
ACGGTCTGCTGAAGTAACTC

Downstream 100 bases:

>100_bases
CCCTCTCCCGGGGGGTAGAGGGGACCGATTCGGGGATATTGGCGATTTCCGCCGACCTGAAACGGCAACTGTGAATCCAG
CGGCGCCAAGACTTTTTGAA

Product: DNA-3-methyladenine glycosylase II

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MPDPYQPASEFLASLDADWQRHIAAVGPCLHQPHPTRDPYESLVRAIAYQQLHAKAGDAIVGRLVGLFPGQTFPRPEQIL
ATDFDQLRGCGFSAGKIATIQGIAQATLDGVVPDYPTALAMEDEALIERLVSLRGVGRWTVEMLLIYSLERPDILPADDF
GVREGYRRLKGLEVQPARKQMIEIGLDWKPFRTVAAWYLWRVPKSPSP

Sequences:

>Translated_208_residues
MPDPYQPASEFLASLDADWQRHIAAVGPCLHQPHPTRDPYESLVRAIAYQQLHAKAGDAIVGRLVGLFPGQTFPRPEQIL
ATDFDQLRGCGFSAGKIATIQGIAQATLDGVVPDYPTALAMEDEALIERLVSLRGVGRWTVEMLLIYSLERPDILPADDF
GVREGYRRLKGLEVQPARKQMIEIGLDWKPFRTVAAWYLWRVPKSPSP
>Mature_207_residues
PDPYQPASEFLASLDADWQRHIAAVGPCLHQPHPTRDPYESLVRAIAYQQLHAKAGDAIVGRLVGLFPGQTFPRPEQILA
TDFDQLRGCGFSAGKIATIQGIAQATLDGVVPDYPTALAMEDEALIERLVSLRGVGRWTVEMLLIYSLERPDILPADDFG
VREGYRRLKGLEVQPARKQMIEIGLDWKPFRTVAAWYLWRVPKSPSP

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, 3-methylguanine, 7-methylguanine, O2- methylthymine, and O2-methylcytosine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG0122

COG function: function code L; 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alkylbase DNA glycosidase alkA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011257
- InterPro:   IPR003265
- InterPro:   IPR003583
- InterPro:   IPR023170 [H]

Pfam domain/function: PF00730 HhH-GPD [H]

EC number: =3.2.2.21 [H]

Molecular weight: Translated: 23202; Mature: 23071

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDPYQPASEFLASLDADWQRHIAAVGPCLHQPHPTRDPYESLVRAIAYQQLHAKAGDAI
CCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHH
VGRLVGLFPGQTFPRPEQILATDFDQLRGCGFSAGKIATIQGIAQATLDGVVPDYPTALA
HHHHHHHCCCCCCCCHHHHHHHCHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHH
MEDEALIERLVSLRGVGRWTVEMLLIYSLERPDILPADDFGVREGYRRLKGLEVQPARKQ
CCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHH
MIEIGLDWKPFRTVAAWYLWRVPKSPSP
HHHHCCCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PDPYQPASEFLASLDADWQRHIAAVGPCLHQPHPTRDPYESLVRAIAYQQLHAKAGDAI
CCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHH
VGRLVGLFPGQTFPRPEQILATDFDQLRGCGFSAGKIATIQGIAQATLDGVVPDYPTALA
HHHHHHHCCCCCCCCHHHHHHHCHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHH
MEDEALIERLVSLRGVGRWTVEMLLIYSLERPDILPADDFGVREGYRRLKGLEVQPARKQ
CCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHH
MIEIGLDWKPFRTVAAWYLWRVPKSPSP
HHHHCCCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]