Click here to switch to the map view.

The map label for this gene is pcs [H]

Identifier: 77458320

GI number: 77458320

Start: 2378106

End: 2378855

Strand: Reverse

Name: pcs [H]

Synonym: Pfl01_2093

Alternate gene names: 77458320

Gene position: 2378855-2378106 (Counterclockwise)

Preceding gene: 77458325

Following gene: 77458317

Centisome position: 36.95

GC content: 59.73

Gene sequence:

>750_bases
TTGCTGCATTTTCTGGAGAACGCCTTCGTGATATCGACCGTCCACATCGCCAGGCTCAAGGCCTGGGGCGCCCATGGTTT
CACCGCGACCGGCGTGGTCACCGCTTTTCTGGCCACCCTTGCCCTGCTGGAAAACCAGCCAATCCACTGCCTGATGTGGC
TCGGCGTGGCGCTGATCGTCGACGGCCTCGACGGGGCGCTGGCACGCAAGGTCAACGTGCAGTCGGTGCTGCCGAGTTTC
GACGGATCGATCCTCGATCTGGTGATCGATTACCTGACCTATGTGTTCATTCCGGCGCTGTTCATCTATCGCTACATTCC
CCTGCCCGACTACACCCTGCTGCTGACCGTATCGCTGATTCTGGTGTCGTCACTGTTCTGCTTCTGCAACGTCAACATGA
AGAGCAAGGACAACTATTTCGTCGGCTTCCCCGCCGCCTGGAACGTGGTTGCGTTGTGTCTGTACATCATCGATCCGGGG
CCGTGGCTCACCTTCCTGACGGTGATCGGCCTGGCGCTGCTGACCGTGACCCGCATGAAATTCCTCCATCCTTTCCGGGT
ACGCCGGTTCATGCCGATCAACATTGCGGTGACGGCGATCTGGCTGCTGTGCAGTCTGTCGCTGGTGCTGAACCACCCGG
TGATCAACCCGCTGGTGATGGGCCTGTGGCTGCTGGCGTCGGCGTACTTTCTCGGCATCTGCATCTGGCGCACGGCGTTG
GAGTGGTTTGACGGTGCGCATCTGAAATAG

Upstream 100 bases:

>100_bases
ATCTTCACGAATGGGTGAACCTTGACCCGGCCCGACCGGTCGATAGCTGCAACCCCGACCCGGTTGGTCGCCGCCCTTGC
TGCCCAAGGGTTTACGCGGC

Downstream 100 bases:

>100_bases
AAGCCCTGTCGCAATCCCTGTGGGAGCGAGCAAGCTCGCTCCCACAGTTGTTTTGCATGACGCTCAGCGTTTGGTTATCA
CCACCTCCAGATACTCGCTC

Product: CDP-diacylglycerol-choline O-phosphatidyltransferase

Products: NA

Alternate protein names: PC synthase; CDP-diglyceride-choline O-phosphatidyltransferase [H]

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MLHFLENAFVISTVHIARLKAWGAHGFTATGVVTAFLATLALLENQPIHCLMWLGVALIVDGLDGALARKVNVQSVLPSF
DGSILDLVIDYLTYVFIPALFIYRYIPLPDYTLLLTVSLILVSSLFCFCNVNMKSKDNYFVGFPAAWNVVALCLYIIDPG
PWLTFLTVIGLALLTVTRMKFLHPFRVRRFMPINIAVTAIWLLCSLSLVLNHPVINPLVMGLWLLASAYFLGICIWRTAL
EWFDGAHLK

Sequences:

>Translated_249_residues
MLHFLENAFVISTVHIARLKAWGAHGFTATGVVTAFLATLALLENQPIHCLMWLGVALIVDGLDGALARKVNVQSVLPSF
DGSILDLVIDYLTYVFIPALFIYRYIPLPDYTLLLTVSLILVSSLFCFCNVNMKSKDNYFVGFPAAWNVVALCLYIIDPG
PWLTFLTVIGLALLTVTRMKFLHPFRVRRFMPINIAVTAIWLLCSLSLVLNHPVINPLVMGLWLLASAYFLGICIWRTAL
EWFDGAHLK
>Mature_249_residues
MLHFLENAFVISTVHIARLKAWGAHGFTATGVVTAFLATLALLENQPIHCLMWLGVALIVDGLDGALARKVNVQSVLPSF
DGSILDLVIDYLTYVFIPALFIYRYIPLPDYTLLLTVSLILVSSLFCFCNVNMKSKDNYFVGFPAAWNVVALCLYIIDPG
PWLTFLTVIGLALLTVTRMKFLHPFRVRRFMPINIAVTAIWLLCSLSLVLNHPVINPLVMGLWLLASAYFLGICIWRTAL
EWFDGAHLK

Specific function: Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP [H]

COG id: COG1183

COG function: function code I; Phosphatidylserine synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.24 [H]

Molecular weight: Translated: 27873; Mature: 27873

Theoretical pI: Translated: 8.13; Mature: 8.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCCCCC
>Mature Secondary Structure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HHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]