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The map label for this gene is yhdY [H]

Identifier: 77458195

GI number: 77458195

Start: 2243936

End: 2245363

Strand: Reverse

Name: yhdY [H]

Synonym: Pfl01_1968

Alternate gene names: 77458195

Gene position: 2245363-2243936 (Counterclockwise)

Preceding gene: 77458196

Following gene: 77458187

Centisome position: 34.87

GC content: 62.89

Gene sequence:

>1428_bases
ATGAGCCTTTTTTCTGCCCACCTGCTGTCCTGGAGCGCTCTGCTGCTGGTGCTCGACACCTTGCTCTGGCACCTCGCACC
GTTCAAGCATCGCGCGCAACGGGTCGCCGTGCGACTGGTGCTGTTCCTGGCCTTCAACGCGCTGGCCATCAACGCCGGCG
TCAGCCCGTTGCAGGCGCCGCTGTTTGCCGACGACCCGGTGGCGCAACTCGGAGCGACGGCACTGGGCATTCTCTGGTGG
CTGTACGCCGCGCGGGTGCTGACCGAAGTCATCGGCCTGATCCTGATGCGCCGCATCGGCCACAGCGGTCGTCTGTTGCA
GGACGTGATCGGTGCGCTGGTGTTTCTGGCGGCCATCGTCGCAGCGGCCGGTTATGTGCTGGATCTGCCGGTCAAAGGCC
TGCTGGCGACTTCCGGGGTGGTGGCGATCGTCATTGGTCTGGCGCTGCAAAGCACCTTGGCCGACGTGTTTTCCGGCATC
GTGCTCAACACCACCAAGCCGTATCAGGTAGATGATCTGGTGGTCATCGATGGTGTCGAAGGCAAGGTGCTCGACATCAA
CTGGCGTGCCACGCACCTGCTGTCCAGCACCGGCACTCTGGCCGTGGTGCCGAACTCGGTGGCGGCCAAGGCCAAGATCG
TCAACCTCAGCCGCCCGAACAACCTGCACGGCGTGTCGATCAGCATCAAGGTGCCGAACCACATTCGCCCGCGCCGAGTG
CTCGACGCCCTCGAGCGCACGCTGCAAGGCAGCAGCAGTCTGTTGCTGACGCCCGCACCGAAAGCGGTGCTGAAAGAGGC
CGGCGACGAAATGTCGGAATACGTGGCCAGCGGATTCATCGCCGAACTGGGCAAGAAAAGCGAGGTGCGCAATCAACTGT
TCGACCTCGCCCACCGCCATCTCGAAGCGGCCGGTATTTCGCGGCACCCGGACGGTGTGATCGAACCTTCGACCCGCGCC
CGCGCGTTGCTCGATGAAGTGAAAATCTTCCGCTCGCTGAGCCACGAGGAACGCGATCGCCTCGCCGAATCGATGGTCGC
GCAGCAGTACAGCGCCGGGCAGGTGGTGCTCGATCTGGAGGAAGTGCCGGACAGCCTGTTCGTGATCGCCACCGGTGTGG
TCAGCGCCAGCGTGCCGGATGGCAATGGTTTCACCGAGGCCGGACGCATGGGGCCGAGTGAGGTCATGGGTGAGCAAAGC
ATCCTCGCGGACACGCCTTCGCAAGCGACGTTTACCGCACTGACGTCTTCGATCATTTATCGCCTCGACAAGAACCTGAC
TCGCCAGTGCATGGAACAGCGCAGTGAAGTGGGTCGGGCGTTGAACAAGTTGCAGGCGGTAAGGCAGCAGAACAGTCGGC
TGGCGTTGATGGCCAAACCGGCACCGGTGAAAAAAGGTGGATTTCTGGGCTGGTTGCAAAAGCGCTGA

Upstream 100 bases:

>100_bases
CCAGGCTGCGGCAGAACTCAAGACCCACCTGAACTGAGTCCAGCCACTCGCCACACCTTCGGGTGTGGCGTTTTCTTTTG
TGTCCGCCGGAGTTCACCTC

Downstream 100 bases:

>100_bases
GCCCTTTTCTGAAGGCAAAAAGAGGCCCGCCATTTTGGCGGGCCTCTTCGTTACAAGCTTACTTGGCAGTGAACTTGGTG
TAGCTGTTGATCAGGTTGCG

Product: cyclic nucleotide-regulated small mechanosensitive ion channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 475; Mature: 474

Protein sequence:

>475_residues
MSLFSAHLLSWSALLLVLDTLLWHLAPFKHRAQRVAVRLVLFLAFNALAINAGVSPLQAPLFADDPVAQLGATALGILWW
LYAARVLTEVIGLILMRRIGHSGRLLQDVIGALVFLAAIVAAAGYVLDLPVKGLLATSGVVAIVIGLALQSTLADVFSGI
VLNTTKPYQVDDLVVIDGVEGKVLDINWRATHLLSSTGTLAVVPNSVAAKAKIVNLSRPNNLHGVSISIKVPNHIRPRRV
LDALERTLQGSSSLLLTPAPKAVLKEAGDEMSEYVASGFIAELGKKSEVRNQLFDLAHRHLEAAGISRHPDGVIEPSTRA
RALLDEVKIFRSLSHEERDRLAESMVAQQYSAGQVVLDLEEVPDSLFVIATGVVSASVPDGNGFTEAGRMGPSEVMGEQS
ILADTPSQATFTALTSSIIYRLDKNLTRQCMEQRSEVGRALNKLQAVRQQNSRLALMAKPAPVKKGGFLGWLQKR

Sequences:

>Translated_475_residues
MSLFSAHLLSWSALLLVLDTLLWHLAPFKHRAQRVAVRLVLFLAFNALAINAGVSPLQAPLFADDPVAQLGATALGILWW
LYAARVLTEVIGLILMRRIGHSGRLLQDVIGALVFLAAIVAAAGYVLDLPVKGLLATSGVVAIVIGLALQSTLADVFSGI
VLNTTKPYQVDDLVVIDGVEGKVLDINWRATHLLSSTGTLAVVPNSVAAKAKIVNLSRPNNLHGVSISIKVPNHIRPRRV
LDALERTLQGSSSLLLTPAPKAVLKEAGDEMSEYVASGFIAELGKKSEVRNQLFDLAHRHLEAAGISRHPDGVIEPSTRA
RALLDEVKIFRSLSHEERDRLAESMVAQQYSAGQVVLDLEEVPDSLFVIATGVVSASVPDGNGFTEAGRMGPSEVMGEQS
ILADTPSQATFTALTSSIIYRLDKNLTRQCMEQRSEVGRALNKLQAVRQQNSRLALMAKPAPVKKGGFLGWLQKR
>Mature_474_residues
SLFSAHLLSWSALLLVLDTLLWHLAPFKHRAQRVAVRLVLFLAFNALAINAGVSPLQAPLFADDPVAQLGATALGILWWL
YAARVLTEVIGLILMRRIGHSGRLLQDVIGALVFLAAIVAAAGYVLDLPVKGLLATSGVVAIVIGLALQSTLADVFSGIV
LNTTKPYQVDDLVVIDGVEGKVLDINWRATHLLSSTGTLAVVPNSVAAKAKIVNLSRPNNLHGVSISIKVPNHIRPRRVL
DALERTLQGSSSLLLTPAPKAVLKEAGDEMSEYVASGFIAELGKKSEVRNQLFDLAHRHLEAAGISRHPDGVIEPSTRAR
ALLDEVKIFRSLSHEERDRLAESMVAQQYSAGQVVLDLEEVPDSLFVIATGVVSASVPDGNGFTEAGRMGPSEVMGEQSI
LADTPSQATFTALTSSIIYRLDKNLTRQCMEQRSEVGRALNKLQAVRQQNSRLALMAKPAPVKKGGFLGWLQKR

Specific function: May play a role in resistance to osmotic downshock [H]

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR006686
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 51179; Mature: 51048

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFSAHLLSWSALLLVLDTLLWHLAPFKHRAQRVAVRLVLFLAFNALAINAGVSPLQAP
CCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
LFADDPVAQLGATALGILWWLYAARVLTEVIGLILMRRIGHSGRLLQDVIGALVFLAAIV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
AAAGYVLDLPVKGLLATSGVVAIVIGLALQSTLADVFSGIVLNTTKPYQVDDLVVIDGVE
HHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCEECCEEEEECCC
GKVLDINWRATHLLSSTGTLAVVPNSVAAKAKIVNLSRPNNLHGVSISIKVPNHIRPRRV
CCEEEECCHHHHHHCCCCCEEECCCCHHHHEEEEECCCCCCCCEEEEEEECCCCCCHHHH
LDALERTLQGSSSLLLTPAPKAVLKEAGDEMSEYVASGFIAELGKKSEVRNQLFDLAHRH
HHHHHHHHCCCCCEEECCCCHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LEAAGISRHPDGVIEPSTRARALLDEVKIFRSLSHEERDRLAESMVAQQYSAGQVVLDLE
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCEEEEHH
EVPDSLFVIATGVVSASVPDGNGFTEAGRMGPSEVMGEQSILADTPSQATFTALTSSIIY
HCCCCEEEEEHHHHEECCCCCCCCCHHCCCCHHHHHCCCHHHCCCCCCHHHHHHHHHHHH
RLDKNLTRQCMEQRSEVGRALNKLQAVRQQNSRLALMAKPAPVKKGGFLGWLQKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHCCC
>Mature Secondary Structure 
SLFSAHLLSWSALLLVLDTLLWHLAPFKHRAQRVAVRLVLFLAFNALAINAGVSPLQAP
CCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
LFADDPVAQLGATALGILWWLYAARVLTEVIGLILMRRIGHSGRLLQDVIGALVFLAAIV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
AAAGYVLDLPVKGLLATSGVVAIVIGLALQSTLADVFSGIVLNTTKPYQVDDLVVIDGVE
HHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCEECCEEEEECCC
GKVLDINWRATHLLSSTGTLAVVPNSVAAKAKIVNLSRPNNLHGVSISIKVPNHIRPRRV
CCEEEECCHHHHHHCCCCCEEECCCCHHHHEEEEECCCCCCCCEEEEEEECCCCCCHHHH
LDALERTLQGSSSLLLTPAPKAVLKEAGDEMSEYVASGFIAELGKKSEVRNQLFDLAHRH
HHHHHHHHCCCCCEEECCCCHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LEAAGISRHPDGVIEPSTRARALLDEVKIFRSLSHEERDRLAESMVAQQYSAGQVVLDLE
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCEEEEHH
EVPDSLFVIATGVVSASVPDGNGFTEAGRMGPSEVMGEQSILADTPSQATFTALTSSIIY
HCCCCEEEEEHHHHEECCCCCCCCCHHCCCCHHHHHCCCHHHCCCCCCHHHHHHHHHHHH
RLDKNLTRQCMEQRSEVGRALNKLQAVRQQNSRLALMAKPAPVKKGGFLGWLQKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]