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The map label for this gene is nahR [H]

Identifier: 77458189

GI number: 77458189

Start: 2238390

End: 2239313

Strand: Direct

Name: nahR [H]

Synonym: Pfl01_1962

Alternate gene names: 77458189

Gene position: 2238390-2239313 (Clockwise)

Preceding gene: 77458188

Following gene: 77458190

Centisome position: 34.77

GC content: 63.1

Gene sequence:

>924_bases
ATGAACCGTAACGATCTGCGCCGCGTCGACATGAACCTGCTGGTGATTTTCGAAGCGCTGATGTTCGAAAAGAACCTGAC
CCGCGTCGCCGAAAAACTGTTCATGGGCCAACCGGCGGTGAGCGCGGCGCTGGGGCGTCTGCGCGATCTGTTCGATGATC
CGCTGTTGCTGCGCAATGGCCGGGGCATGGAGCCGACGGCGCGGGCGCTGGCGATTCTCCAGGAGCTGCAACCGGCGATG
GACGTGATTTCCGGCGCGGTCAGCCGGGCCAAGGAATTCGATCCGGCGACCAGTTGCGACGTGTTTCGCATCGGCTTGTC
GGACGATGCCGAATTCGGTCTGTTCCCGCCGCTGCTGCGCCAGTTGCAGGAAGAGGCGCCGGGGATTGTCGTGGTGGTAC
GTCGCGCCAATTACCTGCTGATGCCGGGGTTGCTGGCTTCGGGGGAAATCTCTGTCGGCGTGAGCTACACCACCGATCTG
CCGGCCAACGCCAAACGCAAGAAATTGCGCGACATTCCCTGCAAGGTCCTGCGTGGCGACAATCGTCCGGGCCCGCTCAC
GCTTGACGAGTATTGCGAGCGCCCGCATGCGATGGTCTCGTTCTCCGGAGACCTGAGCGGCAACATCGACATGGACCTGG
CCAAGGTTGGCCGCAGCCGCCGTGTGGTGCTTGGTGTGCCGCAGTTCAGTGGATTGCGCGCGCTGCTGGCGGGCACCGAG
ATGATCGCCACCGTGCCGGATTATGCGGCGTGTGCGTTGGTGGAAGGGTGTGCGTTGCGGGCTGAAGATCCGCCGTTTCC
GATTGATGCGGCGCAACTGTCGATGGCGTGGAGCGGGGTGCATGACAACGACCCGGCGGAGAAATGGCTGCGGTCGCGGA
TCAGTCAGTTCATGTCGGTGACGCTGGATATTCCGGCGGTTTAG

Upstream 100 bases:

>100_bases
GCCGGTTGAATACGGCCCCTACAAACGCGCGGCCAAAGTGCCGCTGATCGAGTAAAGTTCCCACCTTTCACGTCAGGCTA
AAACAAGGAAAACGTGCCCC

Downstream 100 bases:

>100_bases
CGCGGTGTTGAAAGGCGTTTAAGGTTACTTCCGGTAAGCCACAACGCCTTGCGCCTTTGCCTACGTGTACGCCAGAATCC
GCCGGCTTGTGCGCCTAGGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MNRNDLRRVDMNLLVIFEALMFEKNLTRVAEKLFMGQPAVSAALGRLRDLFDDPLLLRNGRGMEPTARALAILQELQPAM
DVISGAVSRAKEFDPATSCDVFRIGLSDDAEFGLFPPLLRQLQEEAPGIVVVVRRANYLLMPGLLASGEISVGVSYTTDL
PANAKRKKLRDIPCKVLRGDNRPGPLTLDEYCERPHAMVSFSGDLSGNIDMDLAKVGRSRRVVLGVPQFSGLRALLAGTE
MIATVPDYAACALVEGCALRAEDPPFPIDAAQLSMAWSGVHDNDPAEKWLRSRISQFMSVTLDIPAV

Sequences:

>Translated_307_residues
MNRNDLRRVDMNLLVIFEALMFEKNLTRVAEKLFMGQPAVSAALGRLRDLFDDPLLLRNGRGMEPTARALAILQELQPAM
DVISGAVSRAKEFDPATSCDVFRIGLSDDAEFGLFPPLLRQLQEEAPGIVVVVRRANYLLMPGLLASGEISVGVSYTTDL
PANAKRKKLRDIPCKVLRGDNRPGPLTLDEYCERPHAMVSFSGDLSGNIDMDLAKVGRSRRVVLGVPQFSGLRALLAGTE
MIATVPDYAACALVEGCALRAEDPPFPIDAAQLSMAWSGVHDNDPAEKWLRSRISQFMSVTLDIPAV
>Mature_307_residues
MNRNDLRRVDMNLLVIFEALMFEKNLTRVAEKLFMGQPAVSAALGRLRDLFDDPLLLRNGRGMEPTARALAILQELQPAM
DVISGAVSRAKEFDPATSCDVFRIGLSDDAEFGLFPPLLRQLQEEAPGIVVVVRRANYLLMPGLLASGEISVGVSYTTDL
PANAKRKKLRDIPCKVLRGDNRPGPLTLDEYCERPHAMVSFSGDLSGNIDMDLAKVGRSRRVVLGVPQFSGLRALLAGTE
MIATVPDYAACALVEGCALRAEDPPFPIDAAQLSMAWSGVHDNDPAEKWLRSRISQFMSVTLDIPAV

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=310, Percent_Identity=26.4516129032258, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1790147, Length=309, Percent_Identity=23.9482200647249, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1786820, Length=79, Percent_Identity=40.5063291139241, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87081766, Length=89, Percent_Identity=35.9550561797753, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33591; Mature: 33591

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRNDLRRVDMNLLVIFEALMFEKNLTRVAEKLFMGQPAVSAALGRLRDLFDDPLLLRNG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEECC
RGMEPTARALAILQELQPAMDVISGAVSRAKEFDPATSCDVFRIGLSDDAEFGLFPPLLR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCHHHHH
QLQEEAPGIVVVVRRANYLLMPGLLASGEISVGVSYTTDLPANAKRKKLRDIPCKVLRGD
HHHHHCCCEEEEEECCCEEEECCEECCCCEEEEEEEECCCCCCHHHHHHHHCCHHHHCCC
NRPGPLTLDEYCERPHAMVSFSGDLSGNIDMDLAKVGRSRRVVLGVPQFSGLRALLAGTE
CCCCCCCHHHHHCCCCEEEEECCCCCCCCCHHHHHCCCCCEEEEECCCHHHHHHHHHCCH
MIATVPDYAACALVEGCALRAEDPPFPIDAAQLSMAWSGVHDNDPAEKWLRSRISQFMSV
HHHCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
TLDIPAV
HCCCCCC
>Mature Secondary Structure
MNRNDLRRVDMNLLVIFEALMFEKNLTRVAEKLFMGQPAVSAALGRLRDLFDDPLLLRNG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEECC
RGMEPTARALAILQELQPAMDVISGAVSRAKEFDPATSCDVFRIGLSDDAEFGLFPPLLR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCHHHHH
QLQEEAPGIVVVVRRANYLLMPGLLASGEISVGVSYTTDLPANAKRKKLRDIPCKVLRGD
HHHHHCCCEEEEEECCCEEEECCEECCCCEEEEEEEECCCCCCHHHHHHHHCCHHHHCCC
NRPGPLTLDEYCERPHAMVSFSGDLSGNIDMDLAKVGRSRRVVLGVPQFSGLRALLAGTE
CCCCCCCHHHHHCCCCEEEEECCCCCCCCCHHHHHCCCCCEEEEECCCHHHHHHHHHCCH
MIATVPDYAACALVEGCALRAEDPPFPIDAAQLSMAWSGVHDNDPAEKWLRSRISQFMSV
HHHCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
TLDIPAV
HCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]