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The map label for this gene is mauR [H]

Identifier: 77458181

GI number: 77458181

Start: 2228663

End: 2229538

Strand: Direct

Name: mauR [H]

Synonym: Pfl01_1954

Alternate gene names: 77458181

Gene position: 2228663-2229538 (Clockwise)

Preceding gene: 77458176

Following gene: 77458183

Centisome position: 34.62

GC content: 63.36

Gene sequence:

>876_bases
ATGAACTGGGATGATGCAAGGGTGTTTCTAGCGGTCTGCCGCGAGTCGACATTGCGCGGGGCCGCGCGTGTACTGGGCGT
GGATCAGGCGACAGTCGGGCGCCGCATCACGGCACTGGAAAAGTCGCTGGGCGCGACCTTGTTCCTGCGCACCTCCGAGG
GCTATGCACTGACGGCAGTCGGCGAAGCGGCGCTCAAGTCGGTGGAAAAAATGGAGCATTCGGCGCTGGAACTGGAGCGG
CGTATCCAGGGCCTGGACGACCGCCTGACCGGCAGTGTGCGGGTCAGCACCACCGATTCGCTGGCCATCGACTTTCTGAT
CCCGGCGATGGCGCAGTTGCACGAACAGCATCCCGACGTGCGCGTGCAACTGGACGCCTCCACACAGATCCTCAGCCTGG
CCAAACGCGAAGCGGACATCGCCGTGCGCAATACCCGTCCAGACAATCCGGACTTGATCGCCCGGCGCATCGCGCGTTGG
CCGGTGGGGCTGTTTGCCTCGCAGGCTTATGTCGACAGCCATGGCGTACCGGCACCGGGCAGTTCGTTCGAGGGCCACGA
TCTGGTGGTTTACGAGCCGTATCTGCAGGGCAACAAGGATCTGACCCTGGTGTCCGAGCCCATGACTCGCGGGCGGATCG
TCGCCGGTCTGAGTTCCAGTCTGCTGGTGCGGCGCTCGATTGCCGCCGGTCTGGGTGTAGGAGAAATCCCGGTCTACATG
GGCGAGCGTGATGGTCTGGTCAGGCTGTGGCCGGAACGTACGCGGCCGTTACCTTATGAAGTGTGGCTGGTGACCCATGC
GGATTTACGCCACACCGCGCGGGTCAGGGCGGTGATCGAACACATCGTCGAGGCCTTTATGTCGGAAAACGAGTAG

Upstream 100 bases:

>100_bases
TTTGAAAGGTTTATGGCGCCCAGCATATCGGCTATCGTTGCTGCGTTAATGCAGCGAGTTTTCGTGATAGTGATGCGTTT
ATGCATCAATGGAGAACGCT

Downstream 100 bases:

>100_bases
TTGTTCTGCCAATAAAAAACGGCCTTCAGTGAAGGCCGTTTTTTGTGGGCGCCGAAACCTGCCCCTCATGGCATTTCCGG
CAGTTCCTGCGGCCGCAGGT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MNWDDARVFLAVCRESTLRGAARVLGVDQATVGRRITALEKSLGATLFLRTSEGYALTAVGEAALKSVEKMEHSALELER
RIQGLDDRLTGSVRVSTTDSLAIDFLIPAMAQLHEQHPDVRVQLDASTQILSLAKREADIAVRNTRPDNPDLIARRIARW
PVGLFASQAYVDSHGVPAPGSSFEGHDLVVYEPYLQGNKDLTLVSEPMTRGRIVAGLSSSLLVRRSIAAGLGVGEIPVYM
GERDGLVRLWPERTRPLPYEVWLVTHADLRHTARVRAVIEHIVEAFMSENE

Sequences:

>Translated_291_residues
MNWDDARVFLAVCRESTLRGAARVLGVDQATVGRRITALEKSLGATLFLRTSEGYALTAVGEAALKSVEKMEHSALELER
RIQGLDDRLTGSVRVSTTDSLAIDFLIPAMAQLHEQHPDVRVQLDASTQILSLAKREADIAVRNTRPDNPDLIARRIARW
PVGLFASQAYVDSHGVPAPGSSFEGHDLVVYEPYLQGNKDLTLVSEPMTRGRIVAGLSSSLLVRRSIAAGLGVGEIPVYM
GERDGLVRLWPERTRPLPYEVWLVTHADLRHTARVRAVIEHIVEAFMSENE
>Mature_291_residues
MNWDDARVFLAVCRESTLRGAARVLGVDQATVGRRITALEKSLGATLFLRTSEGYALTAVGEAALKSVEKMEHSALELER
RIQGLDDRLTGSVRVSTTDSLAIDFLIPAMAQLHEQHPDVRVQLDASTQILSLAKREADIAVRNTRPDNPDLIARRIARW
PVGLFASQAYVDSHGVPAPGSSFEGHDLVVYEPYLQGNKDLTLVSEPMTRGRIVAGLSSSLLVRRSIAAGLGVGEIPVYM
GERDGLVRLWPERTRPLPYEVWLVTHADLRHTARVRAVIEHIVEAFMSENE

Specific function: Transcriptional activator of the mau genes involved in methylamine metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=289, Percent_Identity=24.5674740484429, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1789639, Length=293, Percent_Identity=20.4778156996587, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787589, Length=191, Percent_Identity=26.7015706806283, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787601, Length=153, Percent_Identity=29.4117647058824, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI145693193, Length=269, Percent_Identity=21.9330855018587, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787128, Length=196, Percent_Identity=27.0408163265306, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87081978, Length=304, Percent_Identity=23.6842105263158, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32107; Mature: 32107

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNWDDARVFLAVCRESTLRGAARVLGVDQATVGRRITALEKSLGATLFLRTSEGYALTAV
CCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEH
GEAALKSVEKMEHSALELERRIQGLDDRLTGSVRVSTTDSLAIDFLIPAMAQLHEQHPDV
HHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCE
RVQLDASTQILSLAKREADIAVRNTRPDNPDLIARRIARWPVGLFASQAYVDSHGVPAPG
EEEECCCHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCC
SSFEGHDLVVYEPYLQGNKDLTLVSEPMTRGRIVAGLSSSLLVRRSIAAGLGVGEIPVYM
CCCCCCEEEEECCCCCCCCCEEEEECCCCCCEEEECCCHHHHHHHHHHHCCCCCCCEEEE
GERDGLVRLWPERTRPLPYEVWLVTHADLRHTARVRAVIEHIVEAFMSENE
CCCCCEEEECCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNWDDARVFLAVCRESTLRGAARVLGVDQATVGRRITALEKSLGATLFLRTSEGYALTAV
CCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEH
GEAALKSVEKMEHSALELERRIQGLDDRLTGSVRVSTTDSLAIDFLIPAMAQLHEQHPDV
HHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCE
RVQLDASTQILSLAKREADIAVRNTRPDNPDLIARRIARWPVGLFASQAYVDSHGVPAPG
EEEECCCHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCC
SSFEGHDLVVYEPYLQGNKDLTLVSEPMTRGRIVAGLSSSLLVRRSIAAGLGVGEIPVYM
CCCCCCEEEEECCCCCCCCCEEEEECCCCCCEEEECCCHHHHHHHHHHHCCCCCCCEEEE
GERDGLVRLWPERTRPLPYEVWLVTHADLRHTARVRAVIEHIVEAFMSENE
CCCCCEEEECCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7957249 [H]