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The map label for this gene is ygfU [H]

Identifier: 77458098

GI number: 77458098

Start: 2133599

End: 2135119

Strand: Direct

Name: ygfU [H]

Synonym: Pfl01_1871

Alternate gene names: 77458098

Gene position: 2133599-2135119 (Clockwise)

Preceding gene: 77458096

Following gene: 77458099

Centisome position: 33.14

GC content: 62.06

Gene sequence:

>1521_bases
ATGAAAACGCCCCATGTTTCACACCAACGGCCCGAGGACGAGAATCTCGGGGTCGGCGCGAATATGGCTTACGGCCTGCA
ACACGTTCTGACCATGTATGGCGGTATCGTCGCGGTGCCACTGATCATCGGTCAGGCCGCCGGGCTTTCGCCGGCGGACA
TCGGTCTGTTGATTGCTGCTTCATTGTTTGCGGGGGGGCTGGCCACGCTGCTGCAAACCCTGGGTTTACCATTTTTCGGC
TGTCAGTTGCCGCTGGTGCAGGGCGTGTCCTTCTCTGGCGTTGCCACCATGGTGGCGATTGTCAGCAGTGGCGGGGAGGG
CGGCTTCCAGTCGGTGCTCGGCGCGGTGATTGCGGCGTCGCTGATCGGCTTGCTGATCACCCCGGTATTTTCGCGAATCA
CCAAATTCTTCCCGCCGCTGGTAACCGGCATTGTGATCACCACCATCGGCCTGACGCTGATGCCCGTGGCTGCACGCTGG
GCCATGGGCGGCAACAGTCACGCGCCTGATTTCGGCAGCATGCAGAACATCGGTCTGGCGGCGGTGACGCTGGTGCTGGT
GCTTCTGTTGAGCAAGGTCGGCAGCTCCACCATCTCGCGTCTGTCGATCCTGTTGGCCATGGTGATCGGCACGGTGCTGG
CGGTGTTCCTCGGCATGGCGGACTTCTCCAGCGTCACCCAAGGCCCGATGTTCGGCTTCCCGACGCCGTTCCATTTCGGC
ATGCCGACCTTCCACTTCGCCGCGATCCTGTCGATGTGCATCGTGGTCATGGTGACCCTGGTGGAAACCTCGGCGGACAT
CCTGGCGGTCGGTGAAATCATCGGCACCAAAGTCGACTCCAAGCGTCTGGGCAACGGCCTGCGGGCGGACATGCTGTCGA
GCATGTTTGCACCGATCTTCGGCTCGTTCACCCAAAGCGCCTTCGCCCAGAACGTCGGGCTGGTGGCGGTGACCGGGATC
AAGAGCCGCTACGTGGTGGCGACCGGCGGTATCTTCCTGGTGATCCTCGGCCTGCTGCCGTTCATGGGCCGGGTCATTGC
AGCCGTGCCGACCTCGGTACTCGGCGGCGCCGGTATCGTGCTGTTCGGCACCGTGGCGGCAAGTGGTATCCGCACGCTGT
CCAAGGTCGATTACCGCAACAACGTCAACCTGATCATCGTCGCCACCTCGATCGGCTTCGGCATGATCCCGATTGCCGCG
CCGAACTTCTACGATCACTTCCCGAGCTGGTTCGCGACCATTTTCCATTCGGGAATCAGCTCGTCGGCGATCATGGCGAT
CCTGCTGAACCTGGCGTTCAACCACTTCACGGCGGGTAACTCGGACCAGCAGTCGGTGTTTGCGGCGGCAGAAGAGCGGA
CCCTGCGTTATCGCGATCTGGCCGCGCTGCGTGAAGGCGACTACTTCAGCGACGGCAAACTGCATGACTGCGACGGCAAT
GAAGTGCCGGTGATCGATCCGGATGCGGATCACGGTCATGGCGCGCCGAAGGTACATGCCAAGAGCAGCGAACACGTCTG
A

Upstream 100 bases:

>100_bases
AACCATTATGTGACTGATAAGTTGTATACAAGTCTATGGACATTTGTCCTGACTCTTGCATACAGTGTGTGCATAACAAA
AACCAGGGAACTCCCCCACC

Downstream 100 bases:

>100_bases
CCGTTGTAGTTGAATGAAAAGGGCCGATCAGTTGCGAAACTGATCGGCCCTTTTTATGGCGCTGACTTTTTCAATGCCAC
AAAAAAGCCCCTGAATCTTT

Product: xanthine/uracil permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 506; Mature: 506

Protein sequence:

>506_residues
MKTPHVSHQRPEDENLGVGANMAYGLQHVLTMYGGIVAVPLIIGQAAGLSPADIGLLIAASLFAGGLATLLQTLGLPFFG
CQLPLVQGVSFSGVATMVAIVSSGGEGGFQSVLGAVIAASLIGLLITPVFSRITKFFPPLVTGIVITTIGLTLMPVAARW
AMGGNSHAPDFGSMQNIGLAAVTLVLVLLLSKVGSSTISRLSILLAMVIGTVLAVFLGMADFSSVTQGPMFGFPTPFHFG
MPTFHFAAILSMCIVVMVTLVETSADILAVGEIIGTKVDSKRLGNGLRADMLSSMFAPIFGSFTQSAFAQNVGLVAVTGI
KSRYVVATGGIFLVILGLLPFMGRVIAAVPTSVLGGAGIVLFGTVAASGIRTLSKVDYRNNVNLIIVATSIGFGMIPIAA
PNFYDHFPSWFATIFHSGISSSAIMAILLNLAFNHFTAGNSDQQSVFAAAEERTLRYRDLAALREGDYFSDGKLHDCDGN
EVPVIDPDADHGHGAPKVHAKSSEHV

Sequences:

>Translated_506_residues
MKTPHVSHQRPEDENLGVGANMAYGLQHVLTMYGGIVAVPLIIGQAAGLSPADIGLLIAASLFAGGLATLLQTLGLPFFG
CQLPLVQGVSFSGVATMVAIVSSGGEGGFQSVLGAVIAASLIGLLITPVFSRITKFFPPLVTGIVITTIGLTLMPVAARW
AMGGNSHAPDFGSMQNIGLAAVTLVLVLLLSKVGSSTISRLSILLAMVIGTVLAVFLGMADFSSVTQGPMFGFPTPFHFG
MPTFHFAAILSMCIVVMVTLVETSADILAVGEIIGTKVDSKRLGNGLRADMLSSMFAPIFGSFTQSAFAQNVGLVAVTGI
KSRYVVATGGIFLVILGLLPFMGRVIAAVPTSVLGGAGIVLFGTVAASGIRTLSKVDYRNNVNLIIVATSIGFGMIPIAA
PNFYDHFPSWFATIFHSGISSSAIMAILLNLAFNHFTAGNSDQQSVFAAAEERTLRYRDLAALREGDYFSDGKLHDCDGN
EVPVIDPDADHGHGAPKVHAKSSEHV
>Mature_506_residues
MKTPHVSHQRPEDENLGVGANMAYGLQHVLTMYGGIVAVPLIIGQAAGLSPADIGLLIAASLFAGGLATLLQTLGLPFFG
CQLPLVQGVSFSGVATMVAIVSSGGEGGFQSVLGAVIAASLIGLLITPVFSRITKFFPPLVTGIVITTIGLTLMPVAARW
AMGGNSHAPDFGSMQNIGLAAVTLVLVLLLSKVGSSTISRLSILLAMVIGTVLAVFLGMADFSSVTQGPMFGFPTPFHFG
MPTFHFAAILSMCIVVMVTLVETSADILAVGEIIGTKVDSKRLGNGLRADMLSSMFAPIFGSFTQSAFAQNVGLVAVTGI
KSRYVVATGGIFLVILGLLPFMGRVIAAVPTSVLGGAGIVLFGTVAASGIRTLSKVDYRNNVNLIIVATSIGFGMIPIAA
PNFYDHFPSWFATIFHSGISSSAIMAILLNLAFNHFTAGNSDQQSVFAAAEERTLRYRDLAALREGDYFSDGKLHDCDGN
EVPVIDPDADHGHGAPKVHAKSSEHV

Specific function: Unknown

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Homo sapiens, GI44680148, Length=440, Percent_Identity=25.9090909090909, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI40316845, Length=440, Percent_Identity=25.9090909090909, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI44680145, Length=522, Percent_Identity=23.3716475095785, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI44680143, Length=527, Percent_Identity=23.3396584440228, Blast_Score=83, Evalue=6e-16,
Organism=Escherichia coli, GI87082181, Length=456, Percent_Identity=39.0350877192982, Blast_Score=311, Evalue=8e-86,
Organism=Escherichia coli, GI1790087, Length=421, Percent_Identity=33.729216152019, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI87082178, Length=460, Percent_Identity=30, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI87081818, Length=402, Percent_Identity=29.8507462686567, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1788843, Length=375, Percent_Identity=27.2, Blast_Score=111, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17558856, Length=512, Percent_Identity=23.046875, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17542262, Length=433, Percent_Identity=21.2471131639723, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17541904, Length=415, Percent_Identity=21.4457831325301, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21356175, Length=457, Percent_Identity=25.382932166302, Blast_Score=101, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017588
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 52665; Mature: 52665

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTPHVSHQRPEDENLGVGANMAYGLQHVLTMYGGIVAVPLIIGQAAGLSPADIGLLIAA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
SLFAGGLATLLQTLGLPFFGCQLPLVQGVSFSGVATMVAIVSSGGEGGFQSVLGAVIAAS
HHHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LIGLLITPVFSRITKFFPPLVTGIVITTIGLTLMPVAARWAMGGNSHAPDFGSMQNIGLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
AVTLVLVLLLSKVGSSTISRLSILLAMVIGTVLAVFLGMADFSSVTQGPMFGFPTPFHFG
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
MPTFHFAAILSMCIVVMVTLVETSADILAVGEIIGTKVDSKRLGNGLRADMLSSMFAPIF
CHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHH
GSFTQSAFAQNVGLVAVTGIKSRYVVATGGIFLVILGLLPFMGRVIAAVPTSVLGGAGIV
HHHHHHHHHHCCCEEEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LFGTVAASGIRTLSKVDYRNNVNLIIVATSIGFGMIPIAAPNFYDHFPSWFATIFHSGIS
HHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
SSAIMAILLNLAFNHFTAGNSDQQSVFAAAEERTLRYRDLAALREGDYFSDGKLHDCDGN
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCC
EVPVIDPDADHGHGAPKVHAKSSEHV
CCCEECCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKTPHVSHQRPEDENLGVGANMAYGLQHVLTMYGGIVAVPLIIGQAAGLSPADIGLLIAA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
SLFAGGLATLLQTLGLPFFGCQLPLVQGVSFSGVATMVAIVSSGGEGGFQSVLGAVIAAS
HHHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LIGLLITPVFSRITKFFPPLVTGIVITTIGLTLMPVAARWAMGGNSHAPDFGSMQNIGLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
AVTLVLVLLLSKVGSSTISRLSILLAMVIGTVLAVFLGMADFSSVTQGPMFGFPTPFHFG
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
MPTFHFAAILSMCIVVMVTLVETSADILAVGEIIGTKVDSKRLGNGLRADMLSSMFAPIF
CHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHH
GSFTQSAFAQNVGLVAVTGIKSRYVVATGGIFLVILGLLPFMGRVIAAVPTSVLGGAGIV
HHHHHHHHHHCCCEEEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LFGTVAASGIRTLSKVDYRNNVNLIIVATSIGFGMIPIAAPNFYDHFPSWFATIFHSGIS
HHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
SSAIMAILLNLAFNHFTAGNSDQQSVFAAAEERTLRYRDLAALREGDYFSDGKLHDCDGN
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCC
EVPVIDPDADHGHGAPKVHAKSSEHV
CCCEECCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]