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The map label for this gene is dhbF [H]

Identifier: 77458076

GI number: 77458076

Start: 2101002

End: 2105153

Strand: Reverse

Name: dhbF [H]

Synonym: Pfl01_1849

Alternate gene names: 77458076

Gene position: 2105153-2101002 (Counterclockwise)

Preceding gene: 77458077

Following gene: 77458070

Centisome position: 32.7

GC content: 63.03

Gene sequence:

>4152_bases
ATGAACGAACTTCTTGATGATGACCTGCTGGCGCTGCTGTTGGCCGATGCCGACGCCGTCGAGCCAGACCCGGTCGCCAC
CCGCCGCGCGCGCCTGGATCGGGCGCCGCTGTCGTACGCCCAGCAACGCCTGTGGCTGGTGCAGCAACAGGCACCGACGA
ATACCGCCTACAACTTGCCGCGCGCCCTGCGCCTGGACGGTGACCTCGATCCGCAGGCGCTGGAAACCGCGCTCAACGCG
GTGATCGACCGCCACGACATCTTGCGCAGTGCCTTTCGCGAAATCGACGGTGTGCCGACCCAGGTGGTCGAGCGCCAGAC
ACGCCTGAACCTCAAGCGCCAGGACCTGTCCTCACTGGATGAGGACACCCGTCGCCTGCACCTCGAACAACGCCTGCAAA
CCCAGGCCCTGCAACCGTTCGACCTGAGCCGCGCGCCGCTGATCCGCACCACCCTGGTCAAGACCGCCGAGCGTGAACAT
GTGCTGCTGCTGAACATGCACCACATCGTGTCTGACGCCTGGTCCAACGCGATCCTCATGCAGGATCTGGCGCGCGCCTA
TGCTCAGGCCAGCGCCGGCCTCGCCCCGGTGCTGAGCGAGTTGCCGATCCAGTACAGCGACTACGCGCAGTGGCAACGCA
GCGAATACCTCGACGGCGTCGCCTGCAAGCGCGCCGACCATTACTGGCGTCAGTATCTGGGTCGCGAACTGCCGGTGCTT
GAACTGCCCGTCGATCATGCCCGCGCCGAAGGCCAGCAACACTTGGCCGGGCGTCATTCTCTGAGCCTTGAGCCCACAGC
GCTGCAAGCCCTCAACCGCTTCTGCCAGAACGAAGGCCTGACCCCGTTCGTGCTGGCGATGGGCGCGTGGCAATTGCTGC
TGGGCCGTTACAGTCAGCAACGCGAATTCACCGTCGGCGTGCCCAACGCCAGCCGCAACCGCAGCGACAGCCAGGAACTG
GTGGGCTTTTTTGTCAGCAGTCAGGTGTACAAGGCGACGCTCGACGGCCAGCAACCGGTGCGGGACTTCCTGCACGCCTT
GCGCGCGCATTCACTGGCGACCCTGGAACACGCCGATTACCCTCTTGAGCTGTTGTTCGATCAACTGCAACGCGGCAGTG
CCACCTCGCTCAATCCGCTGTTCCAGGTGCTGTTCAACTGGCGCACGGGCGGCGGCGAGCCAGCGGCCGTGGAATGGGCC
GGGCTCAACCTGCAATTTCTCGATGCCGGCGAAAGCCAGGCCAAGTTCGACCTGTCGCTGGACGTCGACTTCAGTCCGCA
GAACCTGCAAGCCACCTTCGAATACAGCCGCGACCTCTACACCCCCGCCACCATCGAGCGCATGGCCCGGCACTGGCAGC
AATTGCTGCTGCAACTGATCGCCCGCCCCGATTTGCGCCTGGACGAGTTGCAGTTGCTTGATGCCGAAGAGCATCGGCAG
ACCCTCGCCGAATGGAACCCGCAGCAGACCCGAATCGCCCCGTCGCTATGCCTGCATCAGTTGATCGAAGCGCAGGTCGC
GCGCGATGGTGCCGCCATCGCCCTGACCTTCGGCGCACAACAGGTCAGTTACGCCGAGCTCAACCGCCAGGCCAACCGTC
TGGCCCACCGTTTGATCGCCAACGGTGTCGGCCCGGATGTGCTGGTGGGCATCGCTGCCGAGCGCTCGCCGCAGATGCTG
ATCGGCTTGCTGGCGATTCTCAAGGCCGGCGGCGCCTATGTGCCACTGGACCCGGCCTACCCGGCTGATCGTCTGGCTTA
CATGATCGAGGACAGCCGCATCGACTGGGTCCTGACCCAGTCCCATCTGCGTGAACAATTGCCATTGCCGGCCCACGTGC
GCTGCGTGCTGCTCGACGACGCCACGAGCCTGATCGACGCCGCCGAGCACAACCCCGACGTCGCCGTTCAGCCGGACAAT
CTGGCGTACGTGATCTACACCTCCGGCTCGACCGGCAAACCCAAGGGCGCCCTGCTGGCGCATCACAACGTGGTACGCCT
GTTCGAAGCCACCAGCGGTTGGTTCGGCTTCGATCAGAACGATGTCTGGAGCCTGTTCCATTCCTATGCCTTCGACTTCT
CGGTCTGGGAGATCTTTGGTGCGTTGCTGTACGGTGGACGCCTGGTGATCGTGCCGCACGCCGTCAGTCGTTCTCCGCAA
GACGTCTACACGCTGCTCTGCGAAGAAAAGGTCAGCGTGCTGAACCAGACGCCGTCGGCGTTCAAGCAACTGATGAAAGT
CGCCTGTGAAGCCGACCAGCCGTTGACCCAGCACCTGCGCTACGTGATTTTCGGCGGTGAGGCGATCGAGGTGAAAAGCC
TGCGCCCCTGGTTCGAACGCTTCGGCGATCAGACCCCGCAACTGATCAACATGTACGGCATCACCGAAACCACCGTCCAC
GTCACCTACCGGCCGCTGTCACTGGCTGACCTGAACGCCGAGTCCGCCAGCCCTATCGGCGTGCCGATTGCCGACCTGTC
CTGGTATCTGCTGGATGAAGGCCTCAACCCGGTCGCCAAAGGCTGCACCGGTGAGCTGTACATCGGTCGCGCCGGGCTGG
CCCGGGGTTACCTGAACCGCACCGACCTGACCGCCACGCGCTTCATCCCCGACCCCTTCGACAGTGTTGCGGGTGGGCGT
CTGTACCGTACCGGCGACCTGGCGAAATACTGCAACGACGGCAGCATCGAATACGTCGGACGGATCGACCATCAAGTAAA
AATCCGCGGCTTCCGCATCGAACTGGGCGAGATCGAAGCGCGTCTGCTCGATCAGCCGCAGGTGCAGGATTGCGCGGTGC
TGACCCACGACGGCCCGAGCGGTCTGCAATTGGTGGCCTACGTCATCGCAGCGGATTCGACGGAACTGCGCGACACCCTG
ATCGCTGCTCTGCGGGCGCAATTGCCCGATTACATGGTGCCTGCACACTTGCTGTTCCTTGAGCGCTTCCCCTTGAACGC
CAACGGCAAACTCGACCGCAAAGCCCTGCCGGAACCGGATGCCAGCCTCTGGCAACGAACCTACGTGGCGCCGGGCAATC
CGCTGGAAGAAGCGCTGGCCGGTCTTTGGCAGCAATCGTTGAACATTGAGCGCGTCGGGATCACCGACAACTTCTTCGAG
TTGGGCGGCCATTCGATTCTCGCGATCCAGTTGATCGCCCAGCTCAAGGCACAGCTCGATATCGAAGTACGTCTGCAAGA
GTTGCTGGCTCACCCGACCATCGCCGAACTGTCCGCTTTCGTCGCTCGCCAGCATTTCGCAACCGCGCAGTGTGTGGTCG
AACTCAACAACGCACCGGCCGACGCACCGGCACTGTTCTGCCTGCACCCCAGCGGTGGCATCGTGTTCTGCTATCAGCCG
CTGGCCAAACGCCTGAACAACCGGGCGAAAGTCTACGGCGTGATGCATCGCGGCTTCGCGCAGCAACACAACGACGCGCA
AACCTGGTCGGAGATGATCGCCGACTACAGCCGTGAAATCGTCAACACCCAGCCGCAGGGGCCTTATCACCTGATGGGCT
GGTCGTTGGGTGGCCCGCTGGCCATGGACGTGGCCGCTACGCTGGAGTCTCAGGGTCACGAAGTGGCGTTTCTGGGGCTG
GTCGACGGCACCGTGCCGGCGTCGGCCTTCCCTGCCGACCTGCCACGCTTCCAGCGAACGGACGACGAAGCGCTCGGCGT
CACCTCCGAAGAAGTGCTCGATGCCGTGCACTACTTCAATCTGTTGTTCCCGACCCTGGCACCGCGCACCGCTGCCTACC
TGCAAACGTCGCCGCACGGCAGCGTCAAGGACTTCTATGACTGGGCGGCCGGTCAGGTCGAACCGGGCCAAGGCGACTTG
CTGGCCGTTGTGCAGAACATCAAGAGTGAAGTCATGAACGCCCAGGCGTTCTCGGTGCACGAACGTCTAGTGGAAGCCTT
TGACGCCTTTACCTTCAAGCCACTGCGAGTCAAACCGAGTTGCTGGTGGGCGGTGCCGGAAAAAACCGCAGAAGAACTGG
CCTTCAGCCAGGCGCTGATTCAGCGCTACAGCCAATCGGGCGAACTGAACTGCTCGATACTGTCACCTCTGGAACACCGC
AGCATGATCTTCCAGGATGAACTGCTTGAACCCCTGATCGATACGTTCCTGAGCAACAGTCGAGTGCGCTGA

Upstream 100 bases:

>100_bases
CCAACTGGTACGCATGCAAGGCGGCCAGGTCATCAGCGAAAAAGCCCCGGCAGCCGTCTGCTGAACCGGGCCCGCCCCTG
TCGAGTGTTAAGAGAAAGCC

Downstream 100 bases:

>100_bases
GCCTCTGTGCAGGACCTGAAAAACCCCGTCAATCATTGATTGACGGGGTTTTTCTTTGGCCGCTTTTTCGTTCATCCGTC
GCTGGAGCCTTTCTTCCGGG

Product: amino acid adenylation

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: NA

Number of amino acids: Translated: 1383; Mature: 1383

Protein sequence:

>1383_residues
MNELLDDDLLALLLADADAVEPDPVATRRARLDRAPLSYAQQRLWLVQQQAPTNTAYNLPRALRLDGDLDPQALETALNA
VIDRHDILRSAFREIDGVPTQVVERQTRLNLKRQDLSSLDEDTRRLHLEQRLQTQALQPFDLSRAPLIRTTLVKTAEREH
VLLLNMHHIVSDAWSNAILMQDLARAYAQASAGLAPVLSELPIQYSDYAQWQRSEYLDGVACKRADHYWRQYLGRELPVL
ELPVDHARAEGQQHLAGRHSLSLEPTALQALNRFCQNEGLTPFVLAMGAWQLLLGRYSQQREFTVGVPNASRNRSDSQEL
VGFFVSSQVYKATLDGQQPVRDFLHALRAHSLATLEHADYPLELLFDQLQRGSATSLNPLFQVLFNWRTGGGEPAAVEWA
GLNLQFLDAGESQAKFDLSLDVDFSPQNLQATFEYSRDLYTPATIERMARHWQQLLLQLIARPDLRLDELQLLDAEEHRQ
TLAEWNPQQTRIAPSLCLHQLIEAQVARDGAAIALTFGAQQVSYAELNRQANRLAHRLIANGVGPDVLVGIAAERSPQML
IGLLAILKAGGAYVPLDPAYPADRLAYMIEDSRIDWVLTQSHLREQLPLPAHVRCVLLDDATSLIDAAEHNPDVAVQPDN
LAYVIYTSGSTGKPKGALLAHHNVVRLFEATSGWFGFDQNDVWSLFHSYAFDFSVWEIFGALLYGGRLVIVPHAVSRSPQ
DVYTLLCEEKVSVLNQTPSAFKQLMKVACEADQPLTQHLRYVIFGGEAIEVKSLRPWFERFGDQTPQLINMYGITETTVH
VTYRPLSLADLNAESASPIGVPIADLSWYLLDEGLNPVAKGCTGELYIGRAGLARGYLNRTDLTATRFIPDPFDSVAGGR
LYRTGDLAKYCNDGSIEYVGRIDHQVKIRGFRIELGEIEARLLDQPQVQDCAVLTHDGPSGLQLVAYVIAADSTELRDTL
IAALRAQLPDYMVPAHLLFLERFPLNANGKLDRKALPEPDASLWQRTYVAPGNPLEEALAGLWQQSLNIERVGITDNFFE
LGGHSILAIQLIAQLKAQLDIEVRLQELLAHPTIAELSAFVARQHFATAQCVVELNNAPADAPALFCLHPSGGIVFCYQP
LAKRLNNRAKVYGVMHRGFAQQHNDAQTWSEMIADYSREIVNTQPQGPYHLMGWSLGGPLAMDVAATLESQGHEVAFLGL
VDGTVPASAFPADLPRFQRTDDEALGVTSEEVLDAVHYFNLLFPTLAPRTAAYLQTSPHGSVKDFYDWAAGQVEPGQGDL
LAVVQNIKSEVMNAQAFSVHERLVEAFDAFTFKPLRVKPSCWWAVPEKTAEELAFSQALIQRYSQSGELNCSILSPLEHR
SMIFQDELLEPLIDTFLSNSRVR

Sequences:

>Translated_1383_residues
MNELLDDDLLALLLADADAVEPDPVATRRARLDRAPLSYAQQRLWLVQQQAPTNTAYNLPRALRLDGDLDPQALETALNA
VIDRHDILRSAFREIDGVPTQVVERQTRLNLKRQDLSSLDEDTRRLHLEQRLQTQALQPFDLSRAPLIRTTLVKTAEREH
VLLLNMHHIVSDAWSNAILMQDLARAYAQASAGLAPVLSELPIQYSDYAQWQRSEYLDGVACKRADHYWRQYLGRELPVL
ELPVDHARAEGQQHLAGRHSLSLEPTALQALNRFCQNEGLTPFVLAMGAWQLLLGRYSQQREFTVGVPNASRNRSDSQEL
VGFFVSSQVYKATLDGQQPVRDFLHALRAHSLATLEHADYPLELLFDQLQRGSATSLNPLFQVLFNWRTGGGEPAAVEWA
GLNLQFLDAGESQAKFDLSLDVDFSPQNLQATFEYSRDLYTPATIERMARHWQQLLLQLIARPDLRLDELQLLDAEEHRQ
TLAEWNPQQTRIAPSLCLHQLIEAQVARDGAAIALTFGAQQVSYAELNRQANRLAHRLIANGVGPDVLVGIAAERSPQML
IGLLAILKAGGAYVPLDPAYPADRLAYMIEDSRIDWVLTQSHLREQLPLPAHVRCVLLDDATSLIDAAEHNPDVAVQPDN
LAYVIYTSGSTGKPKGALLAHHNVVRLFEATSGWFGFDQNDVWSLFHSYAFDFSVWEIFGALLYGGRLVIVPHAVSRSPQ
DVYTLLCEEKVSVLNQTPSAFKQLMKVACEADQPLTQHLRYVIFGGEAIEVKSLRPWFERFGDQTPQLINMYGITETTVH
VTYRPLSLADLNAESASPIGVPIADLSWYLLDEGLNPVAKGCTGELYIGRAGLARGYLNRTDLTATRFIPDPFDSVAGGR
LYRTGDLAKYCNDGSIEYVGRIDHQVKIRGFRIELGEIEARLLDQPQVQDCAVLTHDGPSGLQLVAYVIAADSTELRDTL
IAALRAQLPDYMVPAHLLFLERFPLNANGKLDRKALPEPDASLWQRTYVAPGNPLEEALAGLWQQSLNIERVGITDNFFE
LGGHSILAIQLIAQLKAQLDIEVRLQELLAHPTIAELSAFVARQHFATAQCVVELNNAPADAPALFCLHPSGGIVFCYQP
LAKRLNNRAKVYGVMHRGFAQQHNDAQTWSEMIADYSREIVNTQPQGPYHLMGWSLGGPLAMDVAATLESQGHEVAFLGL
VDGTVPASAFPADLPRFQRTDDEALGVTSEEVLDAVHYFNLLFPTLAPRTAAYLQTSPHGSVKDFYDWAAGQVEPGQGDL
LAVVQNIKSEVMNAQAFSVHERLVEAFDAFTFKPLRVKPSCWWAVPEKTAEELAFSQALIQRYSQSGELNCSILSPLEHR
SMIFQDELLEPLIDTFLSNSRVR
>Mature_1383_residues
MNELLDDDLLALLLADADAVEPDPVATRRARLDRAPLSYAQQRLWLVQQQAPTNTAYNLPRALRLDGDLDPQALETALNA
VIDRHDILRSAFREIDGVPTQVVERQTRLNLKRQDLSSLDEDTRRLHLEQRLQTQALQPFDLSRAPLIRTTLVKTAEREH
VLLLNMHHIVSDAWSNAILMQDLARAYAQASAGLAPVLSELPIQYSDYAQWQRSEYLDGVACKRADHYWRQYLGRELPVL
ELPVDHARAEGQQHLAGRHSLSLEPTALQALNRFCQNEGLTPFVLAMGAWQLLLGRYSQQREFTVGVPNASRNRSDSQEL
VGFFVSSQVYKATLDGQQPVRDFLHALRAHSLATLEHADYPLELLFDQLQRGSATSLNPLFQVLFNWRTGGGEPAAVEWA
GLNLQFLDAGESQAKFDLSLDVDFSPQNLQATFEYSRDLYTPATIERMARHWQQLLLQLIARPDLRLDELQLLDAEEHRQ
TLAEWNPQQTRIAPSLCLHQLIEAQVARDGAAIALTFGAQQVSYAELNRQANRLAHRLIANGVGPDVLVGIAAERSPQML
IGLLAILKAGGAYVPLDPAYPADRLAYMIEDSRIDWVLTQSHLREQLPLPAHVRCVLLDDATSLIDAAEHNPDVAVQPDN
LAYVIYTSGSTGKPKGALLAHHNVVRLFEATSGWFGFDQNDVWSLFHSYAFDFSVWEIFGALLYGGRLVIVPHAVSRSPQ
DVYTLLCEEKVSVLNQTPSAFKQLMKVACEADQPLTQHLRYVIFGGEAIEVKSLRPWFERFGDQTPQLINMYGITETTVH
VTYRPLSLADLNAESASPIGVPIADLSWYLLDEGLNPVAKGCTGELYIGRAGLARGYLNRTDLTATRFIPDPFDSVAGGR
LYRTGDLAKYCNDGSIEYVGRIDHQVKIRGFRIELGEIEARLLDQPQVQDCAVLTHDGPSGLQLVAYVIAADSTELRDTL
IAALRAQLPDYMVPAHLLFLERFPLNANGKLDRKALPEPDASLWQRTYVAPGNPLEEALAGLWQQSLNIERVGITDNFFE
LGGHSILAIQLIAQLKAQLDIEVRLQELLAHPTIAELSAFVARQHFATAQCVVELNNAPADAPALFCLHPSGGIVFCYQP
LAKRLNNRAKVYGVMHRGFAQQHNDAQTWSEMIADYSREIVNTQPQGPYHLMGWSLGGPLAMDVAATLESQGHEVAFLGL
VDGTVPASAFPADLPRFQRTDDEALGVTSEEVLDAVHYFNLLFPTLAPRTAAYLQTSPHGSVKDFYDWAAGQVEPGQGDL
LAVVQNIKSEVMNAQAFSVHERLVEAFDAFTFKPLRVKPSCWWAVPEKTAEELAFSQALIQRYSQSGELNCSILSPLEHR
SMIFQDELLEPLIDTFLSNSRVR

Specific function: Specifically adenylates threonine and glycine, and loads them onto their corresponding peptidyl carrier domains [H]

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 acyl carrier domain [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=542, Percent_Identity=26.7527675276753, Blast_Score=136, Evalue=1e-31,
Organism=Homo sapiens, GI187761345, Length=543, Percent_Identity=25.7826887661142, Blast_Score=111, Evalue=5e-24,
Organism=Homo sapiens, GI187761343, Length=543, Percent_Identity=25.7826887661142, Blast_Score=111, Evalue=5e-24,
Organism=Homo sapiens, GI28416953, Length=533, Percent_Identity=25.891181988743, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI13375727, Length=529, Percent_Identity=20.6049149338374, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI157311624, Length=511, Percent_Identity=22.1135029354207, Blast_Score=75, Evalue=3e-13,
Organism=Homo sapiens, GI157311622, Length=511, Percent_Identity=22.1135029354207, Blast_Score=75, Evalue=3e-13,
Organism=Homo sapiens, GI115511026, Length=475, Percent_Identity=22.1052631578947, Blast_Score=72, Evalue=4e-12,
Organism=Homo sapiens, GI122937307, Length=383, Percent_Identity=22.7154046997389, Blast_Score=70, Evalue=1e-11,
Organism=Homo sapiens, GI58082049, Length=507, Percent_Identity=21.1045364891519, Blast_Score=70, Evalue=2e-11,
Organism=Escherichia coli, GI1786801, Length=1214, Percent_Identity=29.9011532125206, Blast_Score=386, Evalue=1e-108,
Organism=Escherichia coli, GI145693145, Length=527, Percent_Identity=24.4781783681214, Blast_Score=108, Evalue=3e-24,
Organism=Escherichia coli, GI1788107, Length=487, Percent_Identity=24.6406570841889, Blast_Score=103, Evalue=7e-23,
Organism=Escherichia coli, GI1790505, Length=539, Percent_Identity=23.0055658627087, Blast_Score=96, Evalue=2e-20,
Organism=Escherichia coli, GI1789201, Length=414, Percent_Identity=26.0869565217391, Blast_Score=87, Evalue=9e-18,
Organism=Escherichia coli, GI1786810, Length=509, Percent_Identity=25.3438113948919, Blast_Score=80, Evalue=1e-15,
Organism=Escherichia coli, GI1786529, Length=388, Percent_Identity=24.7422680412371, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17550940, Length=1204, Percent_Identity=22.7574750830565, Blast_Score=199, Evalue=6e-51,
Organism=Caenorhabditis elegans, GI17556356, Length=609, Percent_Identity=24.7947454844007, Blast_Score=147, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI17558820, Length=530, Percent_Identity=23.2075471698113, Blast_Score=100, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI32563687, Length=542, Percent_Identity=23.6162361623616, Blast_Score=99, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17559526, Length=380, Percent_Identity=25.2631578947368, Blast_Score=91, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI71983001, Length=567, Percent_Identity=20.6349206349206, Blast_Score=68, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71982997, Length=567, Percent_Identity=20.6349206349206, Blast_Score=68, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6319591, Length=777, Percent_Identity=25.2252252252252, Blast_Score=200, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6319264, Length=543, Percent_Identity=25.0460405156538, Blast_Score=91, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6323182, Length=540, Percent_Identity=22.7777777777778, Blast_Score=72, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6319699, Length=369, Percent_Identity=21.4092140921409, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24648676, Length=653, Percent_Identity=31.2404287901991, Blast_Score=241, Evalue=2e-63,
Organism=Drosophila melanogaster, GI24582852, Length=504, Percent_Identity=27.1825396825397, Blast_Score=110, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24581924, Length=544, Percent_Identity=24.2647058823529, Blast_Score=105, Evalue=2e-22,
Organism=Drosophila melanogaster, GI18859661, Length=549, Percent_Identity=24.7723132969035, Blast_Score=98, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24667955, Length=496, Percent_Identity=25.2016129032258, Blast_Score=87, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24667959, Length=496, Percent_Identity=25.2016129032258, Blast_Score=86, Evalue=2e-16,
Organism=Drosophila melanogaster, GI62472339, Length=497, Percent_Identity=25.1509054325956, Blast_Score=86, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21355181, Length=546, Percent_Identity=23.0769230769231, Blast_Score=79, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding; PF00975 Thioesterase [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 154144; Mature: 154144

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNELLDDDLLALLLADADAVEPDPVATRRARLDRAPLSYAQQRLWLVQQQAPTNTAYNLP
CCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHCCC
RALRLDGDLDPQALETALNAVIDRHDILRSAFREIDGVPTQVVERQTRLNLKRQDLSSLD
CEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHH
EDTRRLHLEQRLQTQALQPFDLSRAPLIRTTLVKTAEREHVLLLNMHHIVSDAWSNAILM
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEHHHHHHHHHCCHHHH
QDLARAYAQASAGLAPVLSELPIQYSDYAQWQRSEYLDGVACKRADHYWRQYLGRELPVL
HHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEE
ELPVDHARAEGQQHLAGRHSLSLEPTALQALNRFCQNEGLTPFVLAMGAWQLLLGRYSQQ
ECCCHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCC
REFTVGVPNASRNRSDSQELVGFFVSSQVYKATLDGQQPVRDFLHALRAHSLATLEHADY
CEEEEECCCCCCCCCCHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHCCCC
PLELLFDQLQRGSATSLNPLFQVLFNWRTGGGEPAAVEWAGLNLQFLDAGESQAKFDLSL
CHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCEEEEEECCCCCCEEEEEE
DVDFSPQNLQATFEYSRDLYTPATIERMARHWQQLLLQLIARPDLRLDELQLLDAEEHRQ
ECCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHH
TLAEWNPQQTRIAPSLCLHQLIEAQVARDGAAIALTFGAQQVSYAELNRQANRLAHRLIA
HHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHH
NGVGPDVLVGIAAERSPQMLIGLLAILKAGGAYVPLDPAYPADRLAYMIEDSRIDWVLTQ
CCCCCHHEEEECCCCCHHHHHHHHHHHHCCCCEECCCCCCCHHHHHEEEECCCCEEEEEH
SHLREQLPLPAHVRCVLLDDATSLIDAAEHNPDVAVQPDNLAYVIYTSGSTGKPKGALLA
HHHHHHCCCCCCEEEEEECCHHHHHHHHCCCCCEEECCCCEEEEEEECCCCCCCCCCEEE
HHNVVRLFEATSGWFGFDQNDVWSLFHSYAFDFSVWEIFGALLYGGRLVIVPHAVSRSPQ
HHHHHEEEECCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEEECHHCCCHH
DVYTLLCEEKVSVLNQTPSAFKQLMKVACEADQPLTQHLRYVIFGGEAIEVKSLRPWFER
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHCCEEEEECCCEEEECCCCHHHHH
FGDQTPQLINMYGITETTVHVTYRPLSLADLNAESASPIGVPIADLSWYLLDEGLNPVAK
HCCCCCCCEEEECCCEEEEEEEECCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCHHHC
GCTGELYIGRAGLARGYLNRTDLTATRFIPDPFDSVAGGRLYRTGDLAKYCNDGSIEYVG
CCCCEEEECCHHHHHCCCCCCCCCEECCCCCCHHHHCCCCEEECCCHHHHCCCCCEEEEE
RIDHQVKIRGFRIELGEIEARLLDQPQVQDCAVLTHDGPSGLQLVAYVIAADSTELRDTL
CCCCEEEEEEEEEEHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCHHHHHHH
IAALRAQLPDYMVPAHLLFLERFPLNANGKLDRKALPEPDASLWQRTYVAPGNPLEEALA
HHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCHHHHHH
GLWQQSLNIERVGITDNFFELGGHSILAIQLIAQLKAQLDIEVRLQELLAHPTIAELSAF
HHHHHCCCEEEECCCCCHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHH
VARQHFATAQCVVELNNAPADAPALFCLHPSGGIVFCYQPLAKRLNNRAKVYGVMHRGFA
HHHHHHHHEEEEEEECCCCCCCCEEEEEECCCCEEEEEHHHHHHHCCHHHHHHHHHHHHH
QQHNDAQTWSEMIADYSREIVNTQPQGPYHLMGWSLGGPLAMDVAATLESQGHEVAFLGL
HCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEEEEEE
VDGTVPASAFPADLPRFQRTDDEALGVTSEEVLDAVHYFNLLFPTLAPRTAAYLQTSPHG
ECCCCCCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHEECCCCC
SVKDFYDWAAGQVEPGQGDLLAVVQNIKSEVMNAQAFSVHERLVEAFDAFTFKPLRVKPS
CHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCEEECCC
CWWAVPEKTAEELAFSQALIQRYSQSGELNCSILSPLEHRSMIFQDELLEPLIDTFLSNS
EEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCC
RVR
CCC
>Mature Secondary Structure
MNELLDDDLLALLLADADAVEPDPVATRRARLDRAPLSYAQQRLWLVQQQAPTNTAYNLP
CCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHCCC
RALRLDGDLDPQALETALNAVIDRHDILRSAFREIDGVPTQVVERQTRLNLKRQDLSSLD
CEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHH
EDTRRLHLEQRLQTQALQPFDLSRAPLIRTTLVKTAEREHVLLLNMHHIVSDAWSNAILM
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEHHHHHHHHHCCHHHH
QDLARAYAQASAGLAPVLSELPIQYSDYAQWQRSEYLDGVACKRADHYWRQYLGRELPVL
HHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEE
ELPVDHARAEGQQHLAGRHSLSLEPTALQALNRFCQNEGLTPFVLAMGAWQLLLGRYSQQ
ECCCHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCC
REFTVGVPNASRNRSDSQELVGFFVSSQVYKATLDGQQPVRDFLHALRAHSLATLEHADY
CEEEEECCCCCCCCCCHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHCCCC
PLELLFDQLQRGSATSLNPLFQVLFNWRTGGGEPAAVEWAGLNLQFLDAGESQAKFDLSL
CHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCEEEEEECCCCCCEEEEEE
DVDFSPQNLQATFEYSRDLYTPATIERMARHWQQLLLQLIARPDLRLDELQLLDAEEHRQ
ECCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHH
TLAEWNPQQTRIAPSLCLHQLIEAQVARDGAAIALTFGAQQVSYAELNRQANRLAHRLIA
HHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHH
NGVGPDVLVGIAAERSPQMLIGLLAILKAGGAYVPLDPAYPADRLAYMIEDSRIDWVLTQ
CCCCCHHEEEECCCCCHHHHHHHHHHHHCCCCEECCCCCCCHHHHHEEEECCCCEEEEEH
SHLREQLPLPAHVRCVLLDDATSLIDAAEHNPDVAVQPDNLAYVIYTSGSTGKPKGALLA
HHHHHHCCCCCCEEEEEECCHHHHHHHHCCCCCEEECCCCEEEEEEECCCCCCCCCCEEE
HHNVVRLFEATSGWFGFDQNDVWSLFHSYAFDFSVWEIFGALLYGGRLVIVPHAVSRSPQ
HHHHHEEEECCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEEECHHCCCHH
DVYTLLCEEKVSVLNQTPSAFKQLMKVACEADQPLTQHLRYVIFGGEAIEVKSLRPWFER
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHCCEEEEECCCEEEECCCCHHHHH
FGDQTPQLINMYGITETTVHVTYRPLSLADLNAESASPIGVPIADLSWYLLDEGLNPVAK
HCCCCCCCEEEECCCEEEEEEEECCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCHHHC
GCTGELYIGRAGLARGYLNRTDLTATRFIPDPFDSVAGGRLYRTGDLAKYCNDGSIEYVG
CCCCEEEECCHHHHHCCCCCCCCCEECCCCCCHHHHCCCCEEECCCHHHHCCCCCEEEEE
RIDHQVKIRGFRIELGEIEARLLDQPQVQDCAVLTHDGPSGLQLVAYVIAADSTELRDTL
CCCCEEEEEEEEEEHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCHHHHHHH
IAALRAQLPDYMVPAHLLFLERFPLNANGKLDRKALPEPDASLWQRTYVAPGNPLEEALA
HHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCHHHHHH
GLWQQSLNIERVGITDNFFELGGHSILAIQLIAQLKAQLDIEVRLQELLAHPTIAELSAF
HHHHHCCCEEEECCCCCHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHH
VARQHFATAQCVVELNNAPADAPALFCLHPSGGIVFCYQPLAKRLNNRAKVYGVMHRGFA
HHHHHHHHEEEEEEECCCCCCCCEEEEEECCCCEEEEEHHHHHHHCCHHHHHHHHHHHHH
QQHNDAQTWSEMIADYSREIVNTQPQGPYHLMGWSLGGPLAMDVAATLESQGHEVAFLGL
HCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEEEEEE
VDGTVPASAFPADLPRFQRTDDEALGVTSEEVLDAVHYFNLLFPTLAPRTAAYLQTSPHG
ECCCCCCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHEECCCCC
SVKDFYDWAAGQVEPGQGDLLAVVQNIKSEVMNAQAFSVHERLVEAFDAFTFKPLRVKPS
CHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCEEECCC
CWWAVPEKTAEELAFSQALIQRYSQSGELNCSILSPLEHRSMIFQDELLEPLIDTFLSNS
EEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCC
RVR
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11112781; 9384377; 10568751; 8550523 [H]