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The map label for this gene is aer [H]

Identifier: 77458060

GI number: 77458060

Start: 2051002

End: 2052567

Strand: Reverse

Name: aer [H]

Synonym: Pfl01_1833

Alternate gene names: 77458060

Gene position: 2052567-2051002 (Counterclockwise)

Preceding gene: 77458061

Following gene: 77458056

Centisome position: 31.88

GC content: 62.64

Gene sequence:

>1566_bases
ATGCGTAACAACCAGCCCATTACACAACGCGAACGGACTTTCCCGGCTCAGCAACGGTTGATTTCCACAACCGACGCCAA
GGGCGTGATCACCTACTGCAACGACGCTTTCGTCGAAATCAGCGGGTTTTCGCGTGAGGAACTGATCCGTGCGCCGCACA
ACCTGGTTCGTCACCCTGACGTGCCGGCGGCGGTGTTTTCGCACATGTGGGGCACACTGAAACAAGGCTTGCCATGGATG
GGCATTGTCAAGAATCGCTGCAAGACCGGTGACCATTACTGGGTGAACGCCTATGTAACGCCGGTGTTCGAGGGCAATCA
GGTGGTCGGTTACGAGTCGGTGCGGGTCAAACCCACCGCCGAACAGATCCGCCGTGCCGAAGCGCTCTACCAACGCATCA
ACCAGGGCAAGTCGGCGATTCCTTCGAGCGACAAGTGGCTGCCGATTGTGCAGGACTGGCTGCCGTTCATTCTGGTCAGC
CAGCTGAGCTTCATGATCGGCGCCACGCTGAACTCGCAGTGGGGCTTCGCCCTCGCCGCCGGTCTGTCGGTGCCGCTGGG
CCTGCTGGGCCTGCAATGGCAACAACGCGGGCTCAAGCGCCTGCTGCGTCTGGCCGAGCAGACCACCTCCGACCCGTTGA
TCGCGCAGATGTACACCGACAGCCGTGGCGCCCAGGCGCGTCTGGAAATGTCGATCCTCAGCCAAGAAGCGCGCCTGAAA
ACCTGCCTGACCCGTCTGCAGGACACCGCCGAGCACCTGACCGATCAGGCCAAACAGTCCGACGCCCTGGCGCATAACAG
CTCCAGCGGGCTGGAACGTCAGCGCGTGGAAACCGAACAGGTCGCCACCGCCGTCAACCAGATGGCCGCCACCACCCAGG
AAGTGGCGAGCCACGTCCAACGCACCGCCGACGCCACCCAGGAAGCCAATCGCCTGACCGGTCGCGGCCGCGACATCGCC
GGGGAAACCCGCGAAGCCATCCAGCGCCTGTCGGTCGTGGTCGGTGAAACCGGCCTGACCGTCACCCAACTGGCCAAGGA
CAGCGACGAAATCGGCGGCGTGGTCGACGTGATCAAAGGCATCGCCGACCAAACCAACCTGCTCGCGCTCAACGCCGCGA
TTGAAGCCGCGCGTGCCGGCGAGATGGGCCGTGGTTTTGCCGTGGTCGCCGACGAAGTCCGCCAACTGGCACAACGCACC
AGCGAATCCACCGGCCAGATCCACGCCCTGATCGCCAAACTGCAACAGACTGCATCCAGCGCCGTACAAACCATGGAAGC
CGGGCATCGCCAGGCGGAAGAAGGTGTAGCGCGGGTTCTGGAAGCGGATCAGGCCCTGGTCGGCATCAGCGAAGCGGTGG
CCAACATCACCGACATGACCACCCAGATCGCCGCCGCGACCGAAGAGCAAAGTGCCGTGGCTGAAGAAATCAGCCGCAAC
ATCAGCAACATCTCGGAACTGGCGGACCAGACCTCGGAACAGGCGCATAACTCGGCGCTGTTGAGTGAAGAGCTGACCAA
GACTGCCAACACGCAATACTCGTTGGTGGAGCGGTTTAACCGCTGA

Upstream 100 bases:

>100_bases
CAAGGGCCGTTTTGCGACGCCGTACTTATAAATGAAAAAAAATTTCAATAAATGGCCGACCCCGCCGACAACCTTTCAAA
GCCTTGCGGATTGAAAAACC

Downstream 100 bases:

>100_bases
TTGTTCTGGCAATAAAGAAACCCCGGACAGCGAAAGCTTCCGGGGTTTTTATTGCCTGTCTGAAATGGACGTAGCCAGCA
CCGACCTCTTCGTGGGCAAG

Product: Pas/Pac sensor-containing chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 521; Mature: 521

Protein sequence:

>521_residues
MRNNQPITQRERTFPAQQRLISTTDAKGVITYCNDAFVEISGFSREELIRAPHNLVRHPDVPAAVFSHMWGTLKQGLPWM
GIVKNRCKTGDHYWVNAYVTPVFEGNQVVGYESVRVKPTAEQIRRAEALYQRINQGKSAIPSSDKWLPIVQDWLPFILVS
QLSFMIGATLNSQWGFALAAGLSVPLGLLGLQWQQRGLKRLLRLAEQTTSDPLIAQMYTDSRGAQARLEMSILSQEARLK
TCLTRLQDTAEHLTDQAKQSDALAHNSSSGLERQRVETEQVATAVNQMAATTQEVASHVQRTADATQEANRLTGRGRDIA
GETREAIQRLSVVVGETGLTVTQLAKDSDEIGGVVDVIKGIADQTNLLALNAAIEAARAGEMGRGFAVVADEVRQLAQRT
SESTGQIHALIAKLQQTASSAVQTMEAGHRQAEEGVARVLEADQALVGISEAVANITDMTTQIAAATEEQSAVAEEISRN
ISNISELADQTSEQAHNSALLSEELTKTANTQYSLVERFNR

Sequences:

>Translated_521_residues
MRNNQPITQRERTFPAQQRLISTTDAKGVITYCNDAFVEISGFSREELIRAPHNLVRHPDVPAAVFSHMWGTLKQGLPWM
GIVKNRCKTGDHYWVNAYVTPVFEGNQVVGYESVRVKPTAEQIRRAEALYQRINQGKSAIPSSDKWLPIVQDWLPFILVS
QLSFMIGATLNSQWGFALAAGLSVPLGLLGLQWQQRGLKRLLRLAEQTTSDPLIAQMYTDSRGAQARLEMSILSQEARLK
TCLTRLQDTAEHLTDQAKQSDALAHNSSSGLERQRVETEQVATAVNQMAATTQEVASHVQRTADATQEANRLTGRGRDIA
GETREAIQRLSVVVGETGLTVTQLAKDSDEIGGVVDVIKGIADQTNLLALNAAIEAARAGEMGRGFAVVADEVRQLAQRT
SESTGQIHALIAKLQQTASSAVQTMEAGHRQAEEGVARVLEADQALVGISEAVANITDMTTQIAAATEEQSAVAEEISRN
ISNISELADQTSEQAHNSALLSEELTKTANTQYSLVERFNR
>Mature_521_residues
MRNNQPITQRERTFPAQQRLISTTDAKGVITYCNDAFVEISGFSREELIRAPHNLVRHPDVPAAVFSHMWGTLKQGLPWM
GIVKNRCKTGDHYWVNAYVTPVFEGNQVVGYESVRVKPTAEQIRRAEALYQRINQGKSAIPSSDKWLPIVQDWLPFILVS
QLSFMIGATLNSQWGFALAAGLSVPLGLLGLQWQQRGLKRLLRLAEQTTSDPLIAQMYTDSRGAQARLEMSILSQEARLK
TCLTRLQDTAEHLTDQAKQSDALAHNSSSGLERQRVETEQVATAVNQMAATTQEVASHVQRTADATQEANRLTGRGRDIA
GETREAIQRLSVVVGETGLTVTQLAKDSDEIGGVVDVIKGIADQTNLLALNAAIEAARAGEMGRGFAVVADEVRQLAQRT
SESTGQIHALIAKLQQTASSAVQTMEAGHRQAEEGVARVLEADQALVGISEAVANITDMTTQIAAATEEQSAVAEEISRN
ISNISELADQTSEQAHNSALLSEELTKTANTQYSLVERFNR

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=526, Percent_Identity=31.7490494296578, Blast_Score=229, Evalue=4e-61,
Organism=Escherichia coli, GI1788195, Length=267, Percent_Identity=33.3333333333333, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1788194, Length=242, Percent_Identity=33.8842975206612, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI1787690, Length=237, Percent_Identity=35.0210970464135, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI2367378, Length=194, Percent_Identity=37.6288659793814, Blast_Score=103, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 56961; Mature: 56961

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS50112 PAS ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNNQPITQRERTFPAQQRLISTTDAKGVITYCNDAFVEISGFSREELIRAPHNLVRHPD
CCCCCCCCHHHHCCCHHHHHHHCCCCCCEEEECCCCEEEECCCCHHHHHHCCHHHHCCCC
VPAAVFSHMWGTLKQGLPWMGIVKNRCKTGDHYWVNAYVTPVFEGNQVVGYESVRVKPTA
CHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEEEEEEEECCCEEECCCCEECCCHH
EQIRRAEALYQRINQGKSAIPSSDKWLPIVQDWLPFILVSQLSFMIGATLNSQWGFALAA
HHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
GLSVPLGLLGLQWQQRGLKRLLRLAEQTTSDPLIAQMYTDSRGAQARLEMSILSQEARLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHCCCCCCHHHHHHHHHHHHHHHH
TCLTRLQDTAEHLTDQAKQSDALAHNSSSGLERQRVETEQVATAVNQMAATTQEVASHVQ
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTADATQEANRLTGRGRDIAGETREAIQRLSVVVGETGLTVTQLAKDSDEIGGVVDVIKG
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHCHHHHCHHHHHHHH
IADQTNLLALNAAIEAARAGEMGRGFAVVADEVRQLAQRTSESTGQIHALIAKLQQTASS
HCCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
AVQTMEAGHRQAEEGVARVLEADQALVGISEAVANITDMTTQIAAATEEQSAVAEEISRN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISNISELADQTSEQAHNSALLSEELTKTANTQYSLVERFNR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCC
>Mature Secondary Structure
MRNNQPITQRERTFPAQQRLISTTDAKGVITYCNDAFVEISGFSREELIRAPHNLVRHPD
CCCCCCCCHHHHCCCHHHHHHHCCCCCCEEEECCCCEEEECCCCHHHHHHCCHHHHCCCC
VPAAVFSHMWGTLKQGLPWMGIVKNRCKTGDHYWVNAYVTPVFEGNQVVGYESVRVKPTA
CHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEEEEEEEECCCEEECCCCEECCCHH
EQIRRAEALYQRINQGKSAIPSSDKWLPIVQDWLPFILVSQLSFMIGATLNSQWGFALAA
HHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
GLSVPLGLLGLQWQQRGLKRLLRLAEQTTSDPLIAQMYTDSRGAQARLEMSILSQEARLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHCCCCCCHHHHHHHHHHHHHHHH
TCLTRLQDTAEHLTDQAKQSDALAHNSSSGLERQRVETEQVATAVNQMAATTQEVASHVQ
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTADATQEANRLTGRGRDIAGETREAIQRLSVVVGETGLTVTQLAKDSDEIGGVVDVIKG
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHCHHHHCHHHHHHHH
IADQTNLLALNAAIEAARAGEMGRGFAVVADEVRQLAQRTSESTGQIHALIAKLQQTASS
HCCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
AVQTMEAGHRQAEEGVARVLEADQALVGISEAVANITDMTTQIAAATEEQSAVAEEISRN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISNISELADQTSEQAHNSALLSEELTKTANTQYSLVERFNR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]