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The map label for this gene is anr [H]

Identifier: 77458038

GI number: 77458038

Start: 2023730

End: 2024464

Strand: Reverse

Name: anr [H]

Synonym: Pfl01_1811

Alternate gene names: 77458038

Gene position: 2024464-2023730 (Counterclockwise)

Preceding gene: 77458040

Following gene: 77458037

Centisome position: 31.44

GC content: 60.27

Gene sequence:

>735_bases
ATGTCCGAGCCAGTTAAACTGCGCGCTCACAACCAGGCTAATTGCAAGGATTGCAGCCTGGCCCCTCTCTGCCTGCCACT
TTCGCTGAATCTGGAAGACATGGATGCGCTGGACGAAATCGTTAAACGTGGCCGCCCGTTGAAAAAGGGTGAGTTCCTGT
TCCGTCAGGGCGATACCTTCGATTCCGTTTATGCAGTACGCTCCGGCGCCCTCAAGACCTTCAGCCTGAGCGACACCGGC
GAAGAGCAACTGACCGGCTTCCACCTGCCGAGCGAACTGGTCGGGCTGTCCGGCATGGACACCGAGAAACACCCGGTCTC
CGCCCAGGCGCTGGAAACCACTTCGGTCTGCGAGATTCCGTTCGAACGCCTCGACGAACTGGCCCTGCAATTGCCGCAGC
TGCGCCGTCAGTTGATGCGTGTGATGAGCCGCGAAATTCGCGACGACCAGCAAATGATGTTGCTGCTGTCGAAGAAAACC
GCCGACGAGCGCATCGCCACCTTCCTGGTCAACCTGTCGGCGCGTTTCCGCGCTCGCGGCTTCTCGGCCAACCAGTTCCG
CCTGAGCATGTCGCGCAATGAAATCGGCAACTACCTGGGGCTGGCGGTGGAAACCGTGTCCCGGGTCTTCACCCGCTTCC
AACAGAACGAACTGATCGCCGCCGAGGGCAAGGAAATCCATATTCTCGACCCGATCCAGCTCTGTGCCCTGGCCGGCGGC
TCGCTCGAAGTCTGA

Upstream 100 bases:

>100_bases
GCTTTATGCCGAGGGGGCAATCTCGCCCCAAGCTGGCCTGAATGTCCTCCGCTGGGTTACCCTTACGCCTTATGTGTGTT
TTCCCACAAGGATCCAAGAA

Downstream 100 bases:

>100_bases
TCTCGACCCGCGGCCGAGCGTATCGTTTCAGCCGCGGGTATACTGCGCCGTTTGCAGCCCTGCCAGGACACCTCGACGAT
GGTCTTCGACTCCTTCGACA

Product: Crp/FNR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 243

Protein sequence:

>244_residues
MSEPVKLRAHNQANCKDCSLAPLCLPLSLNLEDMDALDEIVKRGRPLKKGEFLFRQGDTFDSVYAVRSGALKTFSLSDTG
EEQLTGFHLPSELVGLSGMDTEKHPVSAQALETTSVCEIPFERLDELALQLPQLRRQLMRVMSREIRDDQQMMLLLSKKT
ADERIATFLVNLSARFRARGFSANQFRLSMSRNEIGNYLGLAVETVSRVFTRFQQNELIAAEGKEIHILDPIQLCALAGG
SLEV

Sequences:

>Translated_244_residues
MSEPVKLRAHNQANCKDCSLAPLCLPLSLNLEDMDALDEIVKRGRPLKKGEFLFRQGDTFDSVYAVRSGALKTFSLSDTG
EEQLTGFHLPSELVGLSGMDTEKHPVSAQALETTSVCEIPFERLDELALQLPQLRRQLMRVMSREIRDDQQMMLLLSKKT
ADERIATFLVNLSARFRARGFSANQFRLSMSRNEIGNYLGLAVETVSRVFTRFQQNELIAAEGKEIHILDPIQLCALAGG
SLEV
>Mature_243_residues
SEPVKLRAHNQANCKDCSLAPLCLPLSLNLEDMDALDEIVKRGRPLKKGEFLFRQGDTFDSVYAVRSGALKTFSLSDTGE
EQLTGFHLPSELVGLSGMDTEKHPVSAQALETTSVCEIPFERLDELALQLPQLRRQLMRVMSREIRDDQQMMLLLSKKTA
DERIATFLVNLSARFRARGFSANQFRLSMSRNEIGNYLGLAVETVSRVFTRFQQNELIAAEGKEIHILDPIQLCALAGGS
LEV

Specific function: Transcriptional activator of anaerobic gene expression [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=231, Percent_Identity=51.9480519480519, Blast_Score=265, Evalue=1e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 27302; Mature: 27171

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS50042 CNMP_BINDING_3 ; PS00042 HTH_CRP_1 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPVKLRAHNQANCKDCSLAPLCLPLSLNLEDMDALDEIVKRGRPLKKGEFLFRQGDTF
CCCCCEEECCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCEEEECCCCH
DSVYAVRSGALKTFSLSDTGEEQLTGFHLPSELVGLSGMDTEKHPVSAQALETTSVCEIP
HHHHHHHHCCEEEEECCCCCHHHHCCCCCCHHHHCCCCCCCCCCCCCHHHHCCCHHHHCC
FERLDELALQLPQLRRQLMRVMSREIRDDQQMMLLLSKKTADERIATFLVNLSARFRARG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
FSANQFRLSMSRNEIGNYLGLAVETVSRVFTRFQQNELIAAEGKEIHILDPIQLCALAGG
CCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEEECHHHHHHHCCC
SLEV
CCCC
>Mature Secondary Structure 
SEPVKLRAHNQANCKDCSLAPLCLPLSLNLEDMDALDEIVKRGRPLKKGEFLFRQGDTF
CCCCEEECCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCEEEECCCCH
DSVYAVRSGALKTFSLSDTGEEQLTGFHLPSELVGLSGMDTEKHPVSAQALETTSVCEIP
HHHHHHHHCCEEEEECCCCCHHHHCCCCCCHHHHCCCCCCCCCCCCCHHHHCCCHHHHCC
FERLDELALQLPQLRRQLMRVMSREIRDDQQMMLLLSKKTADERIATFLVNLSARFRARG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
FSANQFRLSMSRNEIGNYLGLAVETVSRVFTRFQQNELIAAEGKEIHILDPIQLCALAGG
CCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEEECHHHHHHHCCC
SLEV
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1787797; 1787798; 10984043 [H]