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The map label for this gene is mmgC [H]

Identifier: 77458036

GI number: 77458036

Start: 2021896

End: 2023044

Strand: Direct

Name: mmgC [H]

Synonym: Pfl01_1809

Alternate gene names: 77458036

Gene position: 2021896-2023044 (Clockwise)

Preceding gene: 77458035

Following gene: 77458039

Centisome position: 31.4

GC content: 61.1

Gene sequence:

>1149_bases
ATGCCCGCCTTCCAGGAATACTTCGATCCCAGCCACCAAATGGTCCGCGACAGCGTCAGTCGTTTCGTCGAACGCGAGAT
CCTGCCGGATATCGATGCGTGGGAAGAAGCCGAAAACTTTCCCCGTGAGCTGTACCTCAAGGCCGGCGCGGCCGGCATCC
TCGGCATCGGTTACCCCGAAGCGCTGGGCGGCAGTCACGAAGGTGATCTGTTCGCCAAGATCGCCGCCAGCGAAGAACTG
ATGCGTTGCGGCTCCGGCGGGCTGGTGGCAGGGCTCGGTTCGCTGGATATCGGTTTGCCGCCGATCGTCAAATGGGCCCG
GCCCGAAGTCCGCGATTGCGTCGTCCCCCAAGTGCTCCGCGGCGAGAAGATCAGCGCCTTGGCCGTCACCGAGCCGGGCG
GCGGTTCCGACGTCGCCAACCTGCAGACCCGCGCCGTACGCGATGGCGATTATTACCGGGTCAGTGGCAGCAAAACCTTC
ATCACCAGTGGGGTACGCGCCGACTACTACACGGTCGCGGTACGTACCGGTGCGCCTGGTTTTGGCGGCATCAGCCTGCT
GCTGATCGAGAAGAGTACGCCAGGTTTCACTGTCGGCCGGCAACTGAAGAAAATGGGCTGGTGGGCGTCAGACACCGCTG
AATTGTTCTTCGACGATTGCCGGGTGCCTGTAGGAAATCTGATTGGCGCGGAGAACATGGGCTTTGCCTGCATCATGGGC
AACTTTCAGAGCGAGCGTCTGGCGCTGGCGCTGATGGCCAACATGACCGCACAACTGGCGCTGGAAGAGAGCGTGAAGTG
GGCGAAGGAGCGTGAAGCGTTCGGCAAACCCATCGGCAAGTTCCAGGTGATCAAGCATCGCCTCGCGGAAATGGCCACGA
CGCTGGAAGTCTCGCGGGAGTTCACCTACCGGCAGGCGGCGAAGATGGCGGCGGGGCAGAGCGTGATCAAGGAGATTTCC
ATGGCCAAGAACTTTGCCACGGACACTTCGGATCGCATCACCAATGAAGCGGTGCAGATTCTCGGTGGGCTGGGTTACGT
GCGCGAAAGCCTGGTGGAGCGGCTTTATCGGGATAACCGCATTTTGTCGATTGGCGGCGGGACGCGGGAAGTGATGAACG
AGATCATCAGCAAGCAGATGGGACTGTAA

Upstream 100 bases:

>100_bases
TTGCCGGGCGCAAGCCGATTTCCCTCTGAGCCACACAATTCTGTTGAAAACCAAGCAAGCGCTCGGTTAAGTTCGGCGAA
CCCTTCCATGGAGTTCGCCG

Downstream 100 bases:

>100_bases
TCTTCGGTGTTTGATCGTTCCCACGCGGAGCGTGGGAACGATCGAGGCGCGGGGCTGATTATTTATCAGTCAACGCAAAC
TGCGTCAGGCAGAACGTCGG

Product: acyl-CoA dehydrogenase-like protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MPAFQEYFDPSHQMVRDSVSRFVEREILPDIDAWEEAENFPRELYLKAGAAGILGIGYPEALGGSHEGDLFAKIAASEEL
MRCGSGGLVAGLGSLDIGLPPIVKWARPEVRDCVVPQVLRGEKISALAVTEPGGGSDVANLQTRAVRDGDYYRVSGSKTF
ITSGVRADYYTVAVRTGAPGFGGISLLLIEKSTPGFTVGRQLKKMGWWASDTAELFFDDCRVPVGNLIGAENMGFACIMG
NFQSERLALALMANMTAQLALEESVKWAKEREAFGKPIGKFQVIKHRLAEMATTLEVSREFTYRQAAKMAAGQSVIKEIS
MAKNFATDTSDRITNEAVQILGGLGYVRESLVERLYRDNRILSIGGGTREVMNEIISKQMGL

Sequences:

>Translated_382_residues
MPAFQEYFDPSHQMVRDSVSRFVEREILPDIDAWEEAENFPRELYLKAGAAGILGIGYPEALGGSHEGDLFAKIAASEEL
MRCGSGGLVAGLGSLDIGLPPIVKWARPEVRDCVVPQVLRGEKISALAVTEPGGGSDVANLQTRAVRDGDYYRVSGSKTF
ITSGVRADYYTVAVRTGAPGFGGISLLLIEKSTPGFTVGRQLKKMGWWASDTAELFFDDCRVPVGNLIGAENMGFACIMG
NFQSERLALALMANMTAQLALEESVKWAKEREAFGKPIGKFQVIKHRLAEMATTLEVSREFTYRQAAKMAAGQSVIKEIS
MAKNFATDTSDRITNEAVQILGGLGYVRESLVERLYRDNRILSIGGGTREVMNEIISKQMGL
>Mature_381_residues
PAFQEYFDPSHQMVRDSVSRFVEREILPDIDAWEEAENFPRELYLKAGAAGILGIGYPEALGGSHEGDLFAKIAASEELM
RCGSGGLVAGLGSLDIGLPPIVKWARPEVRDCVVPQVLRGEKISALAVTEPGGGSDVANLQTRAVRDGDYYRVSGSKTFI
TSGVRADYYTVAVRTGAPGFGGISLLLIEKSTPGFTVGRQLKKMGWWASDTAELFFDDCRVPVGNLIGAENMGFACIMGN
FQSERLALALMANMTAQLALEESVKWAKEREAFGKPIGKFQVIKHRLAEMATTLEVSREFTYRQAAKMAAGQSVIKEISM
AKNFATDTSDRITNEAVQILGGLGYVRESLVERLYRDNRILSIGGGTREVMNEIISKQMGL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=378, Percent_Identity=37.3015873015873, Blast_Score=241, Evalue=1e-63,
Organism=Homo sapiens, GI4557233, Length=372, Percent_Identity=37.0967741935484, Blast_Score=225, Evalue=7e-59,
Organism=Homo sapiens, GI226958412, Length=374, Percent_Identity=31.8181818181818, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI7656849, Length=360, Percent_Identity=33.6111111111111, Blast_Score=201, Evalue=7e-52,
Organism=Homo sapiens, GI226958414, Length=372, Percent_Identity=31.989247311828, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI187960098, Length=380, Percent_Identity=32.6315789473684, Blast_Score=192, Evalue=5e-49,
Organism=Homo sapiens, GI4557231, Length=380, Percent_Identity=32.6315789473684, Blast_Score=192, Evalue=5e-49,
Organism=Homo sapiens, GI4501859, Length=376, Percent_Identity=30.3191489361702, Blast_Score=186, Evalue=2e-47,
Organism=Homo sapiens, GI4557235, Length=374, Percent_Identity=32.3529411764706, Blast_Score=161, Evalue=9e-40,
Organism=Homo sapiens, GI76496475, Length=374, Percent_Identity=32.3529411764706, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI21361497, Length=370, Percent_Identity=29.7297297297297, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI4503943, Length=383, Percent_Identity=26.1096605744125, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI7669494, Length=359, Percent_Identity=27.0194986072423, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI38505218, Length=388, Percent_Identity=26.5463917525773, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI211971008, Length=271, Percent_Identity=25.830258302583, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI48976061, Length=271, Percent_Identity=25.830258302583, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI87081958, Length=344, Percent_Identity=32.5581395348837, Blast_Score=177, Evalue=7e-46,
Organism=Escherichia coli, GI1786223, Length=332, Percent_Identity=32.2289156626506, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI87082384, Length=303, Percent_Identity=28.3828382838284, Blast_Score=90, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17570075, Length=370, Percent_Identity=34.3243243243243, Blast_Score=210, Evalue=9e-55,
Organism=Caenorhabditis elegans, GI17538396, Length=370, Percent_Identity=33.5135135135135, Blast_Score=202, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI17534899, Length=374, Percent_Identity=33.1550802139037, Blast_Score=199, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI17505929, Length=384, Percent_Identity=32.8125, Blast_Score=195, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI17551932, Length=376, Percent_Identity=32.7127659574468, Blast_Score=194, Evalue=6e-50,
Organism=Caenorhabditis elegans, GI17569725, Length=382, Percent_Identity=32.1989528795811, Blast_Score=190, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17533517, Length=370, Percent_Identity=31.3513513513514, Blast_Score=189, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17508101, Length=362, Percent_Identity=28.1767955801105, Blast_Score=161, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI17506239, Length=365, Percent_Identity=27.3972602739726, Blast_Score=151, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI71985184, Length=357, Percent_Identity=29.1316526610644, Blast_Score=148, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI71990804, Length=292, Percent_Identity=28.4246575342466, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI71985192, Length=300, Percent_Identity=29, Blast_Score=118, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI17534353, Length=386, Percent_Identity=25.6476683937824, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI32563615, Length=234, Percent_Identity=28.6324786324786, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71982178, Length=278, Percent_Identity=21.5827338129496, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17562446, Length=325, Percent_Identity=24.9230769230769, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI21355753, Length=378, Percent_Identity=32.8042328042328, Blast_Score=213, Evalue=2e-55,
Organism=Drosophila melanogaster, GI21356377, Length=370, Percent_Identity=33.2432432432432, Blast_Score=209, Evalue=2e-54,
Organism=Drosophila melanogaster, GI24660351, Length=364, Percent_Identity=34.3406593406593, Blast_Score=199, Evalue=4e-51,
Organism=Drosophila melanogaster, GI24646207, Length=373, Percent_Identity=31.3672922252011, Blast_Score=181, Evalue=8e-46,
Organism=Drosophila melanogaster, GI24666513, Length=381, Percent_Identity=29.1338582677165, Blast_Score=164, Evalue=6e-41,
Organism=Drosophila melanogaster, GI281363737, Length=336, Percent_Identity=30.0595238095238, Blast_Score=152, Evalue=3e-37,
Organism=Drosophila melanogaster, GI19920834, Length=373, Percent_Identity=24.3967828418231, Blast_Score=82, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 41636; Mature: 41505

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAFQEYFDPSHQMVRDSVSRFVEREILPDIDAWEEAENFPRELYLKAGAAGILGIGYPE
CCCCHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCHHEEHHCCCCCEEECCCHH
ALGGSHEGDLFAKIAASEELMRCGSGGLVAGLGSLDIGLPPIVKWARPEVRDCVVPQVLR
HCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHCCCCHHHHHHHHHHC
GEKISALAVTEPGGGSDVANLQTRAVRDGDYYRVSGSKTFITSGVRADYYTVAVRTGAPG
CCCEEEEEEECCCCCCCHHHHHHHHCCCCCEEEECCCCEEEECCCCCCEEEEEEECCCCC
FGGISLLLIEKSTPGFTVGRQLKKMGWWASDTAELFFDDCRVPVGNLIGAENMGFACIMG
CCCEEEEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHCCCCCCCEEEEEC
NFQSERLALALMANMTAQLALEESVKWAKEREAFGKPIGKFQVIKHRLAEMATTLEVSRE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
FTYRQAAKMAAGQSVIKEISMAKNFATDTSDRITNEAVQILGGLGYVRESLVERLYRDNR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ILSIGGGTREVMNEIISKQMGL
EEEECCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PAFQEYFDPSHQMVRDSVSRFVEREILPDIDAWEEAENFPRELYLKAGAAGILGIGYPE
CCCHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCHHEEHHCCCCCEEECCCHH
ALGGSHEGDLFAKIAASEELMRCGSGGLVAGLGSLDIGLPPIVKWARPEVRDCVVPQVLR
HCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHCCCCHHHHHHHHHHC
GEKISALAVTEPGGGSDVANLQTRAVRDGDYYRVSGSKTFITSGVRADYYTVAVRTGAPG
CCCEEEEEEECCCCCCCHHHHHHHHCCCCCEEEECCCCEEEECCCCCCEEEEEEECCCCC
FGGISLLLIEKSTPGFTVGRQLKKMGWWASDTAELFFDDCRVPVGNLIGAENMGFACIMG
CCCEEEEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHCCCCCCCEEEEEC
NFQSERLALALMANMTAQLALEESVKWAKEREAFGKPIGKFQVIKHRLAEMATTLEVSRE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
FTYRQAAKMAAGQSVIKEISMAKNFATDTSDRITNEAVQILGGLGYVRESLVERLYRDNR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ILSIGGGTREVMNEIISKQMGL
EEEECCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]