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The map label for this gene is apeB [H]

Identifier: 77457917

GI number: 77457917

Start: 1887283

End: 1888572

Strand: Reverse

Name: apeB [H]

Synonym: Pfl01_1690

Alternate gene names: 77457917

Gene position: 1888572-1887283 (Counterclockwise)

Preceding gene: 77457918

Following gene: 77457916

Centisome position: 29.33

GC content: 64.5

Gene sequence:

>1290_bases
ATGCGCGAAGAGTTGAACCAAGGCCTGATCGACTTCCTCAAGGCCTCCCCTACCCCGTTCCACGCCACCGCCAGCCTTGT
TCAACGCCTGGAGGCCGCCGGTTATGTGCGCCTCGACGAGCGCGAAACCTGGCACACCGAAGCCAATGGTCGTTACTACG
TCACCCGTAACGACTCCTCGATCGTCGCGATCAAGATGGGCCGCAACTCGCCGCTGCACGACGGCATCCGCCTGGTCGGC
GCCCACACCGACAGCCCGTGCCTGCGGGTCAAGCCACAACCTGAATTGCAACGCCAGGGCTTCTGGCAGCTCGGCGTCGA
AGTCTACGGCGGTGCGCTGCTGGCGCCATGGTTCGACCGCGACCTGTCGCTGGCCGGCCGCGTCACTTTCCGCCGCGACG
GCAAAGTCGAAAGCCAGCTGATCGACTTCAAGGCCCCGATCGCGATCATTCCCAACCTGGCGATTCACCTCAACCGTGAA
GCCAACCAGGGCTGGGCCATTAACGCCCAGACCGAACTGCCGCCGATTCTCGCGCAGTTCGCCGGTGACGAGCGCGTGGA
CTTCCGCGCGGTGCTCACCGATCAACTGGCCCGCGAACACGGCCTCAACGCCGACGTGGTGCTGGATTACGAGCTGAGCT
TCTACGACACCCAGAGCGCTGCGGTCATCGGCCTGCACGGTGATTTCATCGCCGGCGCGCGCCTGGACAACCTGCTGTCG
TGCTACGCCGGCCTGCAAGCCTTGCTGAACGCCGACACCGAAGAAACCTGCGTGCTGGTGTGCAACGACCACGAAGAAGT
CGGCTCCTGCTCGGCATGCGGCGCCGACGGCCCGATGCTCGAACAGACCCTGCGCCGTCTGCTGCCGGAAGGTGATGAAT
TCGTACGCACCATCCAGAAGTCCCTGCTGGTTTCTGCCGACAACGCCCACGGCGTGCACCCGAACTACGCCGAGAAGCAC
GACGCCAACCACGGCCCGAAACTCAACGCCGGCCCGGTGATCAAGGTCAACAGCAACCAGCGCTACGCCACCAACAGCGA
AACCGCCGGTTTCTTCCGCCATCTGTGCATGGCCGAAGAAGTGCCGGTGCAAAGCTTCGTGGTGCGCAGCGACATGGGTT
GCGGCTCGACCATCGGCCCGATCACCGCCAGCAACCTCGGCGTGCGCACGGTCGACATCGGCCTGCCGACCTTCGCCATG
CACTCGATCCGCGAACTGTGCGGCAGCCATGACCTGGCCCACCTGGTCAAAGTGCTGAGCGCGTTCTACGCCAGCCGCGA
ACTTCCGTAG

Upstream 100 bases:

>100_bases
AAACGCGTGGCCGCCGCTCGTTGACGCGAGCGGCACATGCCATGTCCCAAGCATCAGGCCGATGCGTTAAACTCCCGCCC
ATTGCTGTCTGGAGCTTCTT

Downstream 100 bases:

>100_bases
AACACAGCCGGGATCGCAGCCTCGAGCTGCGGTCCCCCGGCCCGTAAAACCGGCTCATTTCTGATACACATCAGCACCGT
CCATCGAAAACCCACCTAGA

Product: putative aminopeptidase 2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MREELNQGLIDFLKASPTPFHATASLVQRLEAAGYVRLDERETWHTEANGRYYVTRNDSSIVAIKMGRNSPLHDGIRLVG
AHTDSPCLRVKPQPELQRQGFWQLGVEVYGGALLAPWFDRDLSLAGRVTFRRDGKVESQLIDFKAPIAIIPNLAIHLNRE
ANQGWAINAQTELPPILAQFAGDERVDFRAVLTDQLAREHGLNADVVLDYELSFYDTQSAAVIGLHGDFIAGARLDNLLS
CYAGLQALLNADTEETCVLVCNDHEEVGSCSACGADGPMLEQTLRRLLPEGDEFVRTIQKSLLVSADNAHGVHPNYAEKH
DANHGPKLNAGPVIKVNSNQRYATNSETAGFFRHLCMAEEVPVQSFVVRSDMGCGSTIGPITASNLGVRTVDIGLPTFAM
HSIRELCGSHDLAHLVKVLSAFYASRELP

Sequences:

>Translated_429_residues
MREELNQGLIDFLKASPTPFHATASLVQRLEAAGYVRLDERETWHTEANGRYYVTRNDSSIVAIKMGRNSPLHDGIRLVG
AHTDSPCLRVKPQPELQRQGFWQLGVEVYGGALLAPWFDRDLSLAGRVTFRRDGKVESQLIDFKAPIAIIPNLAIHLNRE
ANQGWAINAQTELPPILAQFAGDERVDFRAVLTDQLAREHGLNADVVLDYELSFYDTQSAAVIGLHGDFIAGARLDNLLS
CYAGLQALLNADTEETCVLVCNDHEEVGSCSACGADGPMLEQTLRRLLPEGDEFVRTIQKSLLVSADNAHGVHPNYAEKH
DANHGPKLNAGPVIKVNSNQRYATNSETAGFFRHLCMAEEVPVQSFVVRSDMGCGSTIGPITASNLGVRTVDIGLPTFAM
HSIRELCGSHDLAHLVKVLSAFYASRELP
>Mature_429_residues
MREELNQGLIDFLKASPTPFHATASLVQRLEAAGYVRLDERETWHTEANGRYYVTRNDSSIVAIKMGRNSPLHDGIRLVG
AHTDSPCLRVKPQPELQRQGFWQLGVEVYGGALLAPWFDRDLSLAGRVTFRRDGKVESQLIDFKAPIAIIPNLAIHLNRE
ANQGWAINAQTELPPILAQFAGDERVDFRAVLTDQLAREHGLNADVVLDYELSFYDTQSAAVIGLHGDFIAGARLDNLLS
CYAGLQALLNADTEETCVLVCNDHEEVGSCSACGADGPMLEQTLRRLLPEGDEFVRTIQKSLLVSADNAHGVHPNYAEKH
DANHGPKLNAGPVIKVNSNQRYATNSETAGFFRHLCMAEEVPVQSFVVRSDMGCGSTIGPITASNLGVRTVDIGLPTFAM
HSIRELCGSHDLAHLVKVLSAFYASRELP

Specific function: Unknown

COG id: COG1362

COG function: function code E; Aspartyl aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M18 family [H]

Homologues:

Organism=Homo sapiens, GI156416028, Length=442, Percent_Identity=42.0814479638009, Blast_Score=339, Evalue=3e-93,
Organism=Caenorhabditis elegans, GI17552916, Length=444, Percent_Identity=41.6666666666667, Blast_Score=327, Evalue=1e-89,
Organism=Saccharomyces cerevisiae, GI6321905, Length=457, Percent_Identity=40.2625820568928, Blast_Score=327, Evalue=2e-90,
Organism=Saccharomyces cerevisiae, GI6322746, Length=454, Percent_Identity=27.9735682819383, Blast_Score=196, Evalue=5e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022984
- InterPro:   IPR001948 [H]

Pfam domain/function: PF02127 Peptidase_M18 [H]

EC number: NA

Molecular weight: Translated: 47060; Mature: 47060

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREELNQGLIDFLKASPTPFHATASLVQRLEAAGYVRLDERETWHTEANGRYYVTRNDSS
CCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEECCCCCEEECCCCEEEEEECCCE
IVAIKMGRNSPLHDGIRLVGAHTDSPCLRVKPQPELQRQGFWQLGVEVYGGALLAPWFDR
EEEEEECCCCCCCCCEEEEECCCCCCEEEECCCCCHHHCCHHHCCHHHHCCEEECCCCCC
DLSLAGRVTFRRDGKVESQLIDFKAPIAIIPNLAIHLNREANQGWAINAQTELPPILAQF
CCCEEEEEEEECCCCHHHHHHHCCCCCEECCCEEEEEECCCCCCEEEECCCCCCHHHHHH
AGDERVDFRAVLTDQLAREHGLNADVVLDYELSFYDTQSAAVIGLHGDFIAGARLDNLLS
CCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCEEEEEECCCEECHHHHHHHHH
CYAGLQALLNADTEETCVLVCNDHEEVGSCSACGADGPMLEQTLRRLLPEGDEFVRTIQK
HHHHHHHHHCCCCCCEEEEEECCCHHHCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHH
SLLVSADNAHGVHPNYAEKHDANHGPKLNAGPVIKVNSNQRYATNSETAGFFRHLCMAEE
HHEEECCCCCCCCCCCHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCC
VPVQSFVVRSDMGCGSTIGPITASNLGVRTVDIGLPTFAMHSIRELCGSHDLAHLVKVLS
CCHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHH
AFYASRELP
HHHHHCCCC
>Mature Secondary Structure
MREELNQGLIDFLKASPTPFHATASLVQRLEAAGYVRLDERETWHTEANGRYYVTRNDSS
CCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEECCCCCEEECCCCEEEEEECCCE
IVAIKMGRNSPLHDGIRLVGAHTDSPCLRVKPQPELQRQGFWQLGVEVYGGALLAPWFDR
EEEEEECCCCCCCCCEEEEECCCCCCEEEECCCCCHHHCCHHHCCHHHHCCEEECCCCCC
DLSLAGRVTFRRDGKVESQLIDFKAPIAIIPNLAIHLNREANQGWAINAQTELPPILAQF
CCCEEEEEEEECCCCHHHHHHHCCCCCEECCCEEEEEECCCCCCEEEECCCCCCHHHHHH
AGDERVDFRAVLTDQLAREHGLNADVVLDYELSFYDTQSAAVIGLHGDFIAGARLDNLLS
CCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCEEEEEECCCEECHHHHHHHHH
CYAGLQALLNADTEETCVLVCNDHEEVGSCSACGADGPMLEQTLRRLLPEGDEFVRTIQK
HHHHHHHHHCCCCCCEEEEEECCCHHHCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHH
SLLVSADNAHGVHPNYAEKHDANHGPKLNAGPVIKVNSNQRYATNSETAGFFRHLCMAEE
HHEEECCCCCCCCCCCHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCC
VPVQSFVVRSDMGCGSTIGPITASNLGVRTVDIGLPTFAMHSIRELCGSHDLAHLVKVLS
CCHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHH
AFYASRELP
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA