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The map label for this gene is ybiO [H]

Identifier: 77457915

GI number: 77457915

Start: 1884738

End: 1886897

Strand: Reverse

Name: ybiO [H]

Synonym: Pfl01_1688

Alternate gene names: 77457915

Gene position: 1886897-1884738 (Counterclockwise)

Preceding gene: 77457916

Following gene: 77457913

Centisome position: 29.31

GC content: 62.59

Gene sequence:

>2160_bases
GTGTTCGCTCGTCTTTTTGCCCTGCCCTGCCTGTTTCTCGTCTGCCTGATGACCCTGACGTCGCCGGCACCTGCCGACGC
CGCCGGTCTGCCGGGACTGCTCACGGGTAGCGGCAAGGCTCAGCCCGAAGCTCAGGAACCGCTCGGCCAGTCGCTGGACG
AGGTCATCAAGTCGCTGGAAAACGACAAGCAACGTGCCCAGTTGCTGACCGACCTGAAAAAACTGCGCGATGCCACGAAA
AAAGCCCAGGCCACCCCGGAAGAAGGGGTACTGGGACTGATCGGCGGCACCCTCGCCACTTTCGAAAAACAATTCTCTGG
CGCCGACAGTCCGCTCAATCGCTGGTCCGCTGAATTCGACATGGCCCAGGACGAACTGAAAGGCCTGATGCTGCCGGCCA
GCGAATGGCTGCCGATCATCTTCGCCTTCGCCGTGATCCTCGCGGTCTGGAGCCTGCTCGCCGCCGCACTGATCTGGCTC
GGTCACCGGGTACGCATGCGCTTCGGCCTGACCGAAGAACTGCCGCAACATCCCCGAGCCCTCGACATGCTGCGCTTCGC
CCTGCGCAAGCTCGGGCCGTGGATGATCGCCCTGGTCATCACGGTGTACATGAGTTACGCACTGCCCTCGTCGCTGGGCA
AAAGCCTGGCGATGGTACTGGCTTATGCGCTGGTGGTCGGCACCTGTTTCTCGGCCATCTGCGTGATCGCCTTCTCCGTA
CTCGACGGTCCGCACCGTCATCGCGCGCTGTACATCCTGCGTCACCAGGCCTTTCGGCCGCTGTGGCTGATCGGCAGCTT
CGCCGCGTTCGGTGAAGCCCTGAGCGATCCGCGACTGGTGGCCGGTCTCGGCGTGCACCTGGCCCACACCGCCGCCACCG
TCGCCAATGTCCTCGCGGCGCTGTCGACCGGCCTGTTCATCCTGCGCTTCCGCCGACCGATCGCCCACCTGATCCGCAAC
CAGCCACTGTCCCGCCGCCTGACCCGCCGCGCCCTGAGCGACACCATCGAAATCCTCGGCACCTTCTGGTACGTCCCGGC
GCTGGTGCTGGTGGGTATTTCGCTGTTCGCCACCTTCGTCTCCGCCGGCGACACCAGCACCGCCTTGCGCCAGTCGCTGA
TCTGCACCGTGCTGCTGGTGTTGTGCATGGTCATCAACGGCCTCGTCCGCCGCCACGCCCTCAAACCCCAACGCGGGCCG
AAACGCCACGCGCTATATTCCGAGCGCCTGAAAAGCTTCTTTTACACCCTCGCCCATTTGCTGGTGTGGCTGGCCTTCAT
CGAACTCGGCCTGCGGGTGTGGGGCATGTCACTGATCGGCTTCACCGAAGGCGAAGGCCACGACGTCAGCGTCAAACTGT
TCAGTTTGATCGGCACGCTGATCTTCGCGTGGCTGGTCTGGATCCTCAGCGACACCGCCGTGCACCACGCCCTCACCCGT
TCTCGCAAAGGCCTGGCCAACGCCCGCGCGCAAACCATGATGCCGCTGATCCGCAACGTACTGTTCGTGGCGATCTTCAT
CATCGCCCTGATCGTCGCCCTGGCGAACATGGGCATGAACGTCACGCCCCTGCTGGCCGGTGCCGGCGTGATCGGCCTGG
CGATCGGCTTCGGTGCGCAATCGCTGGTGGCCGACCTGATCACCGGCCTGTTCATCATCATCGAAGACTCTTTGGCCATC
GACGACTACGTCGACGTCGGCGGGCACCTGGGCACCGTCGAAGGCCTGACCATCCGCACCGTACGCCTGCGGGACATCGA
CGGCATCGTCCACACCATCCCGTTCAGCGAAATCAAAAGCATAAAAAACTACTCCCGCGAATTCGGCTACGCCATCTTCC
GCGTCGCCGTGCCGTTCAACATGAGCATCGACGAAGCCATCAAACTGATGCGCGACGTCGGCCAGAAAATGCGCACAGAT
CCACTGCAGCGGCGCAACATCTGGTCACCGCTGGAATTTCAGGGCGTGGAAAGTTTCGAGTCCGGCAACGCGATATTGCG
TGCAAGATTCAAGACCGCACCGATCAAACAATGGGAAGTTTCACGGGCATTCAACCTGTCGCTGAAACGGCATCTGGACG
AGGCCGGACTGGACTTGGCGACGCCAAGGATGAATGTGCAAGTGATCACCGCAGGCGGTGGTGGCCAAACTCAAGAATAG

Upstream 100 bases:

>100_bases
ATCCTGGCCAAACTCAACGAATAAATCCGCGCCCGGCTCGCATTGAATCTGGCGGGCTCGTACACTCGCCCGATCCGCCC
CTTGCGAGGTTGACCGCCTA

Downstream 100 bases:

>100_bases
ACCCGAAGAATCGGGCCAACTTCAAGGCCCTCATCGCTGGCAAGCCAGCTCCCACCACTCACCACGATGAGCGTTAGCTC
GAGTACCGCTCTTGACGTGC

Product: mechanosensitive ion channel MscS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 719; Mature: 719

Protein sequence:

>719_residues
MFARLFALPCLFLVCLMTLTSPAPADAAGLPGLLTGSGKAQPEAQEPLGQSLDEVIKSLENDKQRAQLLTDLKKLRDATK
KAQATPEEGVLGLIGGTLATFEKQFSGADSPLNRWSAEFDMAQDELKGLMLPASEWLPIIFAFAVILAVWSLLAAALIWL
GHRVRMRFGLTEELPQHPRALDMLRFALRKLGPWMIALVITVYMSYALPSSLGKSLAMVLAYALVVGTCFSAICVIAFSV
LDGPHRHRALYILRHQAFRPLWLIGSFAAFGEALSDPRLVAGLGVHLAHTAATVANVLAALSTGLFILRFRRPIAHLIRN
QPLSRRLTRRALSDTIEILGTFWYVPALVLVGISLFATFVSAGDTSTALRQSLICTVLLVLCMVINGLVRRHALKPQRGP
KRHALYSERLKSFFYTLAHLLVWLAFIELGLRVWGMSLIGFTEGEGHDVSVKLFSLIGTLIFAWLVWILSDTAVHHALTR
SRKGLANARAQTMMPLIRNVLFVAIFIIALIVALANMGMNVTPLLAGAGVIGLAIGFGAQSLVADLITGLFIIIEDSLAI
DDYVDVGGHLGTVEGLTIRTVRLRDIDGIVHTIPFSEIKSIKNYSREFGYAIFRVAVPFNMSIDEAIKLMRDVGQKMRTD
PLQRRNIWSPLEFQGVESFESGNAILRARFKTAPIKQWEVSRAFNLSLKRHLDEAGLDLATPRMNVQVITAGGGGQTQE

Sequences:

>Translated_719_residues
MFARLFALPCLFLVCLMTLTSPAPADAAGLPGLLTGSGKAQPEAQEPLGQSLDEVIKSLENDKQRAQLLTDLKKLRDATK
KAQATPEEGVLGLIGGTLATFEKQFSGADSPLNRWSAEFDMAQDELKGLMLPASEWLPIIFAFAVILAVWSLLAAALIWL
GHRVRMRFGLTEELPQHPRALDMLRFALRKLGPWMIALVITVYMSYALPSSLGKSLAMVLAYALVVGTCFSAICVIAFSV
LDGPHRHRALYILRHQAFRPLWLIGSFAAFGEALSDPRLVAGLGVHLAHTAATVANVLAALSTGLFILRFRRPIAHLIRN
QPLSRRLTRRALSDTIEILGTFWYVPALVLVGISLFATFVSAGDTSTALRQSLICTVLLVLCMVINGLVRRHALKPQRGP
KRHALYSERLKSFFYTLAHLLVWLAFIELGLRVWGMSLIGFTEGEGHDVSVKLFSLIGTLIFAWLVWILSDTAVHHALTR
SRKGLANARAQTMMPLIRNVLFVAIFIIALIVALANMGMNVTPLLAGAGVIGLAIGFGAQSLVADLITGLFIIIEDSLAI
DDYVDVGGHLGTVEGLTIRTVRLRDIDGIVHTIPFSEIKSIKNYSREFGYAIFRVAVPFNMSIDEAIKLMRDVGQKMRTD
PLQRRNIWSPLEFQGVESFESGNAILRARFKTAPIKQWEVSRAFNLSLKRHLDEAGLDLATPRMNVQVITAGGGGQTQE
>Mature_719_residues
MFARLFALPCLFLVCLMTLTSPAPADAAGLPGLLTGSGKAQPEAQEPLGQSLDEVIKSLENDKQRAQLLTDLKKLRDATK
KAQATPEEGVLGLIGGTLATFEKQFSGADSPLNRWSAEFDMAQDELKGLMLPASEWLPIIFAFAVILAVWSLLAAALIWL
GHRVRMRFGLTEELPQHPRALDMLRFALRKLGPWMIALVITVYMSYALPSSLGKSLAMVLAYALVVGTCFSAICVIAFSV
LDGPHRHRALYILRHQAFRPLWLIGSFAAFGEALSDPRLVAGLGVHLAHTAATVANVLAALSTGLFILRFRRPIAHLIRN
QPLSRRLTRRALSDTIEILGTFWYVPALVLVGISLFATFVSAGDTSTALRQSLICTVLLVLCMVINGLVRRHALKPQRGP
KRHALYSERLKSFFYTLAHLLVWLAFIELGLRVWGMSLIGFTEGEGHDVSVKLFSLIGTLIFAWLVWILSDTAVHHALTR
SRKGLANARAQTMMPLIRNVLFVAIFIIALIVALANMGMNVTPLLAGAGVIGLAIGFGAQSLVADLITGLFIIIEDSLAI
DDYVDVGGHLGTVEGLTIRTVRLRDIDGIVHTIPFSEIKSIKNYSREFGYAIFRVAVPFNMSIDEAIKLMRDVGQKMRTD
PLQRRNIWSPLEFQGVESFESGNAILRARFKTAPIKQWEVSRAFNLSLKRHLDEAGLDLATPRMNVQVITAGGGGQTQE

Specific function: Unknown

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI87081787, Length=304, Percent_Identity=33.8815789473684, Blast_Score=132, Evalue=7e-32,
Organism=Escherichia coli, GI1789291, Length=208, Percent_Identity=27.4038461538462, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 78908; Mature: 78908

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFARLFALPCLFLVCLMTLTSPAPADAAGLPGLLTGSGKAQPEAQEPLGQSLDEVIKSLE
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHH
NDKQRAQLLTDLKKLRDATKKAQATPEEGVLGLIGGTLATFEKQFSGADSPLNRWSAEFD
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
MAQDELKGLMLPASEWLPIIFAFAVILAVWSLLAAALIWLGHRVRMRFGLTEELPQHPRA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCHH
LDMLRFALRKLGPWMIALVITVYMSYALPSSLGKSLAMVLAYALVVGTCFSAICVIAFSV
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDGPHRHRALYILRHQAFRPLWLIGSFAAFGEALSDPRLVAGLGVHLAHTAATVANVLAA
HCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
LSTGLFILRFRRPIAHLIRNQPLSRRLTRRALSDTIEILGTFWYVPALVLVGISLFATFV
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAGDTSTALRQSLICTVLLVLCMVINGLVRRHALKPQRGPKRHALYSERLKSFFYTLAHL
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LVWLAFIELGLRVWGMSLIGFTEGEGHDVSVKLFSLIGTLIFAWLVWILSDTAVHHALTR
HHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRKGLANARAQTMMPLIRNVLFVAIFIIALIVALANMGMNVTPLLAGAGVIGLAIGFGAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHCCHH
SLVADLITGLFIIIEDSLAIDDYVDVGGHLGTVEGLTIRTVRLRDIDGIVHTIPFSEIKS
HHHHHHHHHHHHHEECCCCHHHHHHCCCCCCCCCCCEEEEEEEEHHCCHHHHCCHHHHHH
IKNYSREFGYAIFRVAVPFNMSIDEAIKLMRDVGQKMRTDPLQRRNIWSPLEFQGVESFE
HHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCHHCC
SGNAILRARFKTAPIKQWEVSRAFNLSLKRHLDEAGLDLATPRMNVQVITAGGGGQTQE
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCC
>Mature Secondary Structure
MFARLFALPCLFLVCLMTLTSPAPADAAGLPGLLTGSGKAQPEAQEPLGQSLDEVIKSLE
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHH
NDKQRAQLLTDLKKLRDATKKAQATPEEGVLGLIGGTLATFEKQFSGADSPLNRWSAEFD
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
MAQDELKGLMLPASEWLPIIFAFAVILAVWSLLAAALIWLGHRVRMRFGLTEELPQHPRA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCHH
LDMLRFALRKLGPWMIALVITVYMSYALPSSLGKSLAMVLAYALVVGTCFSAICVIAFSV
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDGPHRHRALYILRHQAFRPLWLIGSFAAFGEALSDPRLVAGLGVHLAHTAATVANVLAA
HCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
LSTGLFILRFRRPIAHLIRNQPLSRRLTRRALSDTIEILGTFWYVPALVLVGISLFATFV
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAGDTSTALRQSLICTVLLVLCMVINGLVRRHALKPQRGPKRHALYSERLKSFFYTLAHL
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LVWLAFIELGLRVWGMSLIGFTEGEGHDVSVKLFSLIGTLIFAWLVWILSDTAVHHALTR
HHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRKGLANARAQTMMPLIRNVLFVAIFIIALIVALANMGMNVTPLLAGAGVIGLAIGFGAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHCCHH
SLVADLITGLFIIIEDSLAIDDYVDVGGHLGTVEGLTIRTVRLRDIDGIVHTIPFSEIKS
HHHHHHHHHHHHHEECCCCHHHHHHCCCCCCCCCCCEEEEEEEEHHCCHHHHCCHHHHHH
IKNYSREFGYAIFRVAVPFNMSIDEAIKLMRDVGQKMRTDPLQRRNIWSPLEFQGVESFE
HHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCHHCC
SGNAILRARFKTAPIKQWEVSRAFNLSLKRHLDEAGLDLATPRMNVQVITAGGGGQTQE
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]