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The map label for this gene is fabH [H]

Identifier: 77457751

GI number: 77457751

Start: 1713079

End: 1714005

Strand: Direct

Name: fabH [H]

Synonym: Pfl01_1524

Alternate gene names: 77457751

Gene position: 1713079-1714005 (Clockwise)

Preceding gene: 77457750

Following gene: 77457752

Centisome position: 26.61

GC content: 58.25

Gene sequence:

>927_bases
ATGATTGGCATAAAAAGCATTGCGAGCTACGTTCCTGTAGCCGGCGTGGATAACTACGCACAAGGTGCGAAATTCGAGAA
GGATGAAGAGTTCATCCTTGGCAAGATCGGTTCGGCCTTCCTGCCGCGCAAAGACGCGGAACAGGAGACCTCCGATCTGT
GCGTTGAAGCGGCCAATGCGTTGTTTGCCAGCAATCCGGATCTGAAACGCGAGTCCATCGACGCACTGATCGTCGTCACC
CAGAACGGTGACGAAGAAGGCCTGCCGCACACCGCAGCCATCGTTCAGGACAAGCTTGGTCTGCCAACCAACGTGGCCGC
GTTCGACATTTCCCTGGGGTGCTCCGGTTACGTCTACGGCATCTATGCGATCAAAGGTTTCATGGAAGCTGCCGGCCTCA
AGAACGGCCTGCTGATCACCGCTGACCCGTATTCGAAGATCGTTGACCCGGAAGACCGCAACACCACCATGCTGTTTGGC
GACGCTGCTACCGCCACCTGGATGGGCGAAGACCCGGTCTGGGCGCTGGGCAAGGCCAAGTTCGGCACCGACGGTTCCGG
CGCACCGCACCTGAAAGTCACCGATGGCGTGTTCTTCATGAACGGCCGTCAGGTGTTCAACTTCGCGCTGCTCAAGGTGC
CGGCCCACCTGCACGAACTGCTCGACGATTCCGGTCTCAAGGCCGATGACATCGATGCCTTCTGCATTCACCAGGGCAGT
GCGGCGATTGTCGACGCCGTGGCGCGGCGCTTCGAAGGCGAGCCGGAGAAGTTCATCAAGGACATGGTCGAGACCGGCAA
CACCGTGTCGTCCAGTGTGCCGCTGCTGCTGGAAAAACACGTGATGGATTCCGACTGGAATCGCATTGCAATCAGTGGTT
TCGGTGTCGGTTTGTCATGGGGGTCGGCGATTATTTATCGTCCTTGA

Upstream 100 bases:

>100_bases
TCCCCGTGGCTGCCCGTTGTGGCGGCCGTTTTCTGTTTGTCGGCGCCCCTCGAATCCTTGCGAGCGGTGGTATTGGGCAG
TTTATTATTGGGAAGCCGTA

Downstream 100 bases:

>100_bases
ATCCGCTAAGAACGACGGATACAAAAATAGCGTTCAAGGGTTAACCTTGAACGCTATTTTTTTTGCCTGAAGGGAGCGCG
AGGCGTCATGAGTGAGTTTT

Product: 3-oxoacyl-(acyl-carrier-protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MIGIKSIASYVPVAGVDNYAQGAKFEKDEEFILGKIGSAFLPRKDAEQETSDLCVEAANALFASNPDLKRESIDALIVVT
QNGDEEGLPHTAAIVQDKLGLPTNVAAFDISLGCSGYVYGIYAIKGFMEAAGLKNGLLITADPYSKIVDPEDRNTTMLFG
DAATATWMGEDPVWALGKAKFGTDGSGAPHLKVTDGVFFMNGRQVFNFALLKVPAHLHELLDDSGLKADDIDAFCIHQGS
AAIVDAVARRFEGEPEKFIKDMVETGNTVSSSVPLLLEKHVMDSDWNRIAISGFGVGLSWGSAIIYRP

Sequences:

>Translated_308_residues
MIGIKSIASYVPVAGVDNYAQGAKFEKDEEFILGKIGSAFLPRKDAEQETSDLCVEAANALFASNPDLKRESIDALIVVT
QNGDEEGLPHTAAIVQDKLGLPTNVAAFDISLGCSGYVYGIYAIKGFMEAAGLKNGLLITADPYSKIVDPEDRNTTMLFG
DAATATWMGEDPVWALGKAKFGTDGSGAPHLKVTDGVFFMNGRQVFNFALLKVPAHLHELLDDSGLKADDIDAFCIHQGS
AAIVDAVARRFEGEPEKFIKDMVETGNTVSSSVPLLLEKHVMDSDWNRIAISGFGVGLSWGSAIIYRP
>Mature_308_residues
MIGIKSIASYVPVAGVDNYAQGAKFEKDEEFILGKIGSAFLPRKDAEQETSDLCVEAANALFASNPDLKRESIDALIVVT
QNGDEEGLPHTAAIVQDKLGLPTNVAAFDISLGCSGYVYGIYAIKGFMEAAGLKNGLLITADPYSKIVDPEDRNTTMLFG
DAATATWMGEDPVWALGKAKFGTDGSGAPHLKVTDGVFFMNGRQVFNFALLKVPAHLHELLDDSGLKADDIDAFCIHQGS
AAIVDAVARRFEGEPEKFIKDMVETGNTVSSSVPLLLEKHVMDSDWNRIAISGFGVGLSWGSAIIYRP

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=242, Percent_Identity=25.6198347107438, Blast_Score=96, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 33023; Mature: 33023

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGIKSIASYVPVAGVDNYAQGAKFEKDEEFILGKIGSAFLPRKDAEQETSDLCVEAANA
CCCHHHHHHHCCCCCCCCHHCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
LFASNPDLKRESIDALIVVTQNGDEEGLPHTAAIVQDKLGLPTNVAAFDISLGCSGYVYG
HHCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCEEEEEEEECCCCCEEH
IYAIKGFMEAAGLKNGLLITADPYSKIVDPEDRNTTMLFGDAATATWMGEDPVWALGKAK
HHHHHHHHHHCCCCCCEEEEECCHHHCCCCCCCCEEEEEECCCEEEECCCCCEEEECCCC
FGTDGSGAPHLKVTDGVFFMNGRQVFNFALLKVPAHLHELLDDSGLKADDIDAFCIHQGS
CCCCCCCCCEEEEECCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCC
AAIVDAVARRFEGEPEKFIKDMVETGNTVSSSVPLLLEKHVMDSDWNRIAISGFGVGLSW
HHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCEEEEEEECEEECC
GSAIIYRP
CCEEEECC
>Mature Secondary Structure
MIGIKSIASYVPVAGVDNYAQGAKFEKDEEFILGKIGSAFLPRKDAEQETSDLCVEAANA
CCCHHHHHHHCCCCCCCCHHCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
LFASNPDLKRESIDALIVVTQNGDEEGLPHTAAIVQDKLGLPTNVAAFDISLGCSGYVYG
HHCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCEEEEEEEECCCCCEEH
IYAIKGFMEAAGLKNGLLITADPYSKIVDPEDRNTTMLFGDAATATWMGEDPVWALGKAK
HHHHHHHHHHCCCCCCEEEEECCHHHCCCCCCCCEEEEEECCCEEEECCCCCEEEECCCC
FGTDGSGAPHLKVTDGVFFMNGRQVFNFALLKVPAHLHELLDDSGLKADDIDAFCIHQGS
CCCCCCCCCEEEEECCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCC
AAIVDAVARRFEGEPEKFIKDMVETGNTVSSSVPLLLEKHVMDSDWNRIAISGFGVGLSW
HHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCEEEEEEECEEECC
GSAIIYRP
CCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]