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The map label for this gene is trkH [H]

Identifier: 77457706

GI number: 77457706

Start: 1659774

End: 1661228

Strand: Reverse

Name: trkH [H]

Synonym: Pfl01_1479

Alternate gene names: 77457706

Gene position: 1661228-1659774 (Counterclockwise)

Preceding gene: 77457708

Following gene: 77457704

Centisome position: 25.8

GC content: 62.68

Gene sequence:

>1455_bases
ATGGCGTTGCCGACCTTACGGATCATTGGTTTCATCATCGGCATCTTCCTGATCACCCTGGCCATCGCCATGGTCGTGCC
CATGGCCACCCTGGTGATTTTCGAGCGCACCGGCGATCTGCCGTCGTTCCTCTGGGCGAGCATGATCACCTTCGTCGCCG
GCCTCGCGCTGGTGATTCCGGGGCGTCCGGAACACATCCACCTGCGCCCCCGGGACATGTACCTGCTGACCGTCAGCAGC
TGGCTGGTGGTGTGCATCTTTGCCGCGCTGCCGTTTTTGCTGACCCAGCACATCAGCTACACCGACTCGTTCTTCGAAAG
CATGTCCGGCATCACGGCCACCGGGTCGACCGTGCTCAACCACCTGGACGACATGTCCCCCGGCATCCTGATGTGGCGCT
CGCTGCTGCACTGGATCGGCGGCATCGGCTTCATCGGCATGGCGGTGGCGATCCTGCCGCTGCTGCGCATCGGTGGCATG
CGCCTGTTCCAGACCGAATCCTCGGACCGCTCGGAAAAGGTCATGCCCCGCTCGCACATGGTGGCGCGGCTGATCGTGGC
GGCCTACGTCGGCATCACGATTCTCGGCAGCCTGGCGTTCTGGTGGGCCGGGATGAGCCCGTTCGATGCGATCAACCACG
CGATGTCAGCGATTTCCACAGGCGGGTTCTCGACCTCCGACCAGTCCCTGGCCAAGTGGACGCAACCGGCGGTGCACTGG
GTGGCCGTGGTGGTGATGATTCTCGGCAGTCTGCCGTTCACCCTGTACGTGGCGACGCTGCGCGGCAACCGTCGGGCGCT
GATCAAGGATCAACAGGTGCAGGGTTTGCTCGGGATGTTGCTGGCGACCTGGCTGGTGCTCGGCACCTGGTACTGGTGGA
CTACCAATCTGCATTGGCTGGACGCGCTGCGGCATGTGGCGCTGAACGTGACGTCGGTGGTCACTACCACCGGATTTGCG
CTGGGGGACTACAGCCTGTGGGGCAACTTCTCGCTGATGCTGTTCTTCTATCTGGGCTTCGTCGGCGGCTGCTCCGGCTC
GACGGCGGGCGGGATCAAGATCTTCCGTTTCCAGGTCGCCTACATCCTGCTCAAGGCCAACCTTAACCAGTTGATTCACC
CGCGTGCGGTGATCAAACAGAAGTACAACGGTCACCGCCTCGACGAAGAGATCGTCCGTTCGATTCTGACCTTTTCGTTC
TTCTTCGCCATCACCATCTGCGTGATCGCCCTGTTGCTGTCGCTGTTGGGCGTGGACTGGATGACGGCGTTGACCGGCGC
CGCCAGCACCGTCTCCGGCGTAGGTCCGGGCCTGGGCGAGACCATCGGCCCGGCCGGCAACTTCGCCAGCCTGCCGGATG
CGGCCAAATGGATTCTGTCGTTCGGCATGCTGCTCGGCCGACTGGAGATCATTACGGTGTTTGTACTGTGTATTCCGGCG
TTCTGGCGTCACTGA

Upstream 100 bases:

>100_bases
GTCCGGCTATTCTAGCTGCAAGTGATCCAGACGCGTCGGTTTACATGCCTTGCACCGCAGGTAGAATGGCGCCCTTCCCA
CATCAGCCCGAGCGGACTTC

Downstream 100 bases:

>100_bases
TCGCCTTCGGCGCTTCCAGCAACCGCGCCCGATAATCGCCGGGCGTGGTGTCGAACCAGCGGCGGAAGGCGCGGAAGAAA
TTGCTCGGGTCGGCAAAGCC

Product: K+ transporter Trk

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MALPTLRIIGFIIGIFLITLAIAMVVPMATLVIFERTGDLPSFLWASMITFVAGLALVIPGRPEHIHLRPRDMYLLTVSS
WLVVCIFAALPFLLTQHISYTDSFFESMSGITATGSTVLNHLDDMSPGILMWRSLLHWIGGIGFIGMAVAILPLLRIGGM
RLFQTESSDRSEKVMPRSHMVARLIVAAYVGITILGSLAFWWAGMSPFDAINHAMSAISTGGFSTSDQSLAKWTQPAVHW
VAVVVMILGSLPFTLYVATLRGNRRALIKDQQVQGLLGMLLATWLVLGTWYWWTTNLHWLDALRHVALNVTSVVTTTGFA
LGDYSLWGNFSLMLFFYLGFVGGCSGSTAGGIKIFRFQVAYILLKANLNQLIHPRAVIKQKYNGHRLDEEIVRSILTFSF
FFAITICVIALLLSLLGVDWMTALTGAASTVSGVGPGLGETIGPAGNFASLPDAAKWILSFGMLLGRLEIITVFVLCIPA
FWRH

Sequences:

>Translated_484_residues
MALPTLRIIGFIIGIFLITLAIAMVVPMATLVIFERTGDLPSFLWASMITFVAGLALVIPGRPEHIHLRPRDMYLLTVSS
WLVVCIFAALPFLLTQHISYTDSFFESMSGITATGSTVLNHLDDMSPGILMWRSLLHWIGGIGFIGMAVAILPLLRIGGM
RLFQTESSDRSEKVMPRSHMVARLIVAAYVGITILGSLAFWWAGMSPFDAINHAMSAISTGGFSTSDQSLAKWTQPAVHW
VAVVVMILGSLPFTLYVATLRGNRRALIKDQQVQGLLGMLLATWLVLGTWYWWTTNLHWLDALRHVALNVTSVVTTTGFA
LGDYSLWGNFSLMLFFYLGFVGGCSGSTAGGIKIFRFQVAYILLKANLNQLIHPRAVIKQKYNGHRLDEEIVRSILTFSF
FFAITICVIALLLSLLGVDWMTALTGAASTVSGVGPGLGETIGPAGNFASLPDAAKWILSFGMLLGRLEIITVFVLCIPA
FWRH
>Mature_483_residues
ALPTLRIIGFIIGIFLITLAIAMVVPMATLVIFERTGDLPSFLWASMITFVAGLALVIPGRPEHIHLRPRDMYLLTVSSW
LVVCIFAALPFLLTQHISYTDSFFESMSGITATGSTVLNHLDDMSPGILMWRSLLHWIGGIGFIGMAVAILPLLRIGGMR
LFQTESSDRSEKVMPRSHMVARLIVAAYVGITILGSLAFWWAGMSPFDAINHAMSAISTGGFSTSDQSLAKWTQPAVHWV
AVVVMILGSLPFTLYVATLRGNRRALIKDQQVQGLLGMLLATWLVLGTWYWWTTNLHWLDALRHVALNVTSVVTTTGFAL
GDYSLWGNFSLMLFFYLGFVGGCSGSTAGGIKIFRFQVAYILLKANLNQLIHPRAVIKQKYNGHRLDEEIVRSILTFSFF
FAITICVIALLLSLLGVDWMTALTGAASTVSGVGPGLGETIGPAGNFASLPDAAKWILSFGMLLGRLEIITVFVLCIPAF
WRH

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI1787626, Length=490, Percent_Identity=32.0408163265306, Blast_Score=234, Evalue=7e-63,
Organism=Escherichia coli, GI48994987, Length=486, Percent_Identity=34.156378600823, Blast_Score=227, Evalue=1e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 53074; Mature: 52942

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALPTLRIIGFIIGIFLITLAIAMVVPMATLVIFERTGDLPSFLWASMITFVAGLALVIP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEC
GRPEHIHLRPRDMYLLTVSSWLVVCIFAALPFLLTQHISYTDSFFESMSGITATGSTVLN
CCCCEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
HLDDMSPGILMWRSLLHWIGGIGFIGMAVAILPLLRIGGMRLFQTESSDRSEKVMPRSHM
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHCCCHHHH
VARLIVAAYVGITILGSLAFWWAGMSPFDAINHAMSAISTGGFSTSDQSLAKWTQPAVHW
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
VAVVVMILGSLPFTLYVATLRGNRRALIKDQQVQGLLGMLLATWLVLGTWYWWTTNLHWL
HHHHHHHHCCCCHHHEEEHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
DALRHVALNVTSVVTTTGFALGDYSLWGNFSLMLFFYLGFVGGCSGSTAGGIKIFRFQVA
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
YILLKANLNQLIHPRAVIKQKYNGHRLDEEIVRSILTFSFFFAITICVIALLLSLLGVDW
HHHHHHHHHHHHCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTALTGAASTVSGVGPGLGETIGPAGNFASLPDAAKWILSFGMLLGRLEIITVFVLCIPA
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FWRH
HHCC
>Mature Secondary Structure 
ALPTLRIIGFIIGIFLITLAIAMVVPMATLVIFERTGDLPSFLWASMITFVAGLALVIP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEC
GRPEHIHLRPRDMYLLTVSSWLVVCIFAALPFLLTQHISYTDSFFESMSGITATGSTVLN
CCCCEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
HLDDMSPGILMWRSLLHWIGGIGFIGMAVAILPLLRIGGMRLFQTESSDRSEKVMPRSHM
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHCCCHHHH
VARLIVAAYVGITILGSLAFWWAGMSPFDAINHAMSAISTGGFSTSDQSLAKWTQPAVHW
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
VAVVVMILGSLPFTLYVATLRGNRRALIKDQQVQGLLGMLLATWLVLGTWYWWTTNLHWL
HHHHHHHHCCCCHHHEEEHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
DALRHVALNVTSVVTTTGFALGDYSLWGNFSLMLFFYLGFVGGCSGSTAGGIKIFRFQVA
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
YILLKANLNQLIHPRAVIKQKYNGHRLDEEIVRSILTFSFFFAITICVIALLLSLLGVDW
HHHHHHHHHHHHCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTALTGAASTVSGVGPGLGETIGPAGNFASLPDAAKWILSFGMLLGRLEIITVFVLCIPA
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FWRH
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]