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The map label for this gene is yciR [C]

Identifier: 77457479

GI number: 77457479

Start: 1423661

End: 1425943

Strand: Reverse

Name: yciR [C]

Synonym: Pfl01_1252

Alternate gene names: 77457479

Gene position: 1425943-1423661 (Counterclockwise)

Preceding gene: 77457480

Following gene: 77457477

Centisome position: 22.15

GC content: 61.8

Gene sequence:

>2283_bases
ATGGAGTGGCTTGGTTTGCAGTTCGTTGCCGAGCAGCCGGAGAGCGGGCAGGTCATCCTCAATTGCACACACAATCCCCT
GCTGGTGCTGGTGGCTTACCTGGTCGCCTGCGCCGCGAGCTTCGCCACCCTCGACATGGCCGAACGGGTCGCCCACGCTG
AAGAGCCCGGCTCGCAGCGGATATGGCGCTGGATCGGTGCCACCTGTCTGGCCGGCGGCATCTGGGCCATGCACTTCATC
AGCATGCTGGCGTTCCAGGCGCCGATCGGCATTCAGTACGACCTGCCCGTGACCCTGTTTTCCCTGGTGATCGCGCTACT
GGCGTCCTGGCTGGCGATGCACACCCTGAGCACGCCCCAGCCGAGCCTGCTGCAGTACCTCAAGACCGCCATCGTCATTG
GTCTGGGCATCGCCGGCATGCACTACGTCGGCATGGCCGCCATCGAATCCGCCGCCTCGGCTTACTACGACCCCACTCTG
TTTCTGGCCTCGATCGTGATCGCGATCGGCGCCAGCTTCGCCGCACTGTGGGTGGCCGGTTATCTGCGCGAAGGCAGCGG
CCTGCACATCCAGATGCTCAAATACGTGGCGGCGCTGATTCTCGGTGCGGGCATCCTCAGCATGCATTTCACCGGCATGG
CGGCGCTGCAACTGGTGCTGCCCGAAGGGCAACTGCCGACCCTGGCGTCGCAAACCAGCCATTTGCAGTTGGGCCTGACC
GTCGCGCTGATCACCTTGCTGATTCTTGGCAGCGCCATCAGCGCCGCATTGGCCGACAAGAAGCTGCAGAACAAGGAGCA
CGATCTGCGCCGGGTCAACGCCCTGCTCAGCCAGCTGGATCAGGCACGCATGTCGCTGCAGCACGTGGCCAACTACGACG
CGCTGACCAACCTGATCAACCGGCGTGGCTTCAATCAGATCTTCGCTGAAAAACTCAGCCAGAAAACCAGCGAAGGCGGG
ATGCTGGCAGTGATGTTTCTCGACATCGACCACTTCAAACGCATCAATGACAGCCTCGGCCATGACGCCGGCGACGAACT
GCTGAAGGTCATTGCCCAGCACATCAAGGGCTCGGTGCGCAGCCATGAAGATGTGGTGGCGCGGTTCGGCGGCGACGAGT
TCTGCATCCTGATCGGTCTGCGCGACCGCGAAGAGGCGCGCAACCTGGCCCAGCGCATCATGCTCAAGATGAAAGAGCCG
ATCGAACTGGCCGGACGGCGCATGGTGATGACCACCAGCATCGGCATCAGCCTGTTTCCCGAGGACGGGTCCACCTGCGA
TGAACTGCTCAAGCACGCGGATCTGGCGCTGTACCAGTCCAAGGGCGCCGGGCGCAACGGCGTGCACTTTTTCGATTCCA
ATCTGAAAAACCGCGCCAGCCTTGAACTGCAACTGGAGGAAGAGTTGCGCCACGCGCTGCGTCAGGAGAACGGTCTGCTG
CTGTATTACCAGCCGATCTTCGAACTCAAGACCGGCAAGGTTACCAAGCTTGAAGCGCTGATCCGCTGGCAGCACCCGGT
GCACGGCCTGCTCACCCCGGACCGATTCATTGCCATCGCCGAAAACAACGGCCTGATTGCCGAACTCGACAACTGGGTCC
TGCGCAAGGCCTGTGAGGACCTTGGCGAGCTGTCGCGCCATGGCTGTGAAGAACTGAAGATTGCCTGGAACTGCTCACCG
CTGAATCTGGCCCGGGAAGAACTGGCCAATGAAATCGAGCATGCCTTGCGCAGCGCCGGGGTCGCCCCGGAACGGCTGGA
ACTGGAAGTCACCGAAAACGCCTTGATGGGCAACATCGCCAACACCCTGGTGCTGCTGCGGCAGATCCGCGCCCTCGGCG
TGTCACTGTCGATCGACGACTTCGGTACCGGCTATTCGTCGCTGGCCTATCTCAAACGCCTGCCGCTCAACACCCTGAAG
GTCGACCGCTCGTTCATCCTCGACATTCCCAAGGCCACCGCCGACATGGAGATCGTCCAGGCGATCATCGTCATGGCGCA
CACCCTGCACTTGCAGGTGGTCACCGAAGGCGTCGAAAGCCTGGAGCAATACGAATTCCTGGAGCGCTCGGGCTGCGACT
TCATTCAGGGTTACCTGCTCAGCCGCCCGGTGCCACTGGCCGAACTGCGTCCGGTGCTGGAGGAAATCAATCAGCGCAAA
CACGCGCACGCGGTCAATCCGTTGAGTCTGGCGCGCGGTACATTTGCACCAGTGTCGCTGGATCCTTCTGCAAAAAGCCT
TGTGCCCCATGCAGGCGCATCAGTTGTGCGGCCAATCCGCTGA

Upstream 100 bases:

>100_bases
ATGTGCCACTACCGCTTGCACGGCAAAAACCGCCTCTATACTGCAAACATTCGCCTGCGTTGATGACGCAGTAAGGACGT
ATTCAGAGACGGGGCATGCT

Downstream 100 bases:

>100_bases
TCGGCGTGGCCGAGCCGGTTTCCCGGGAAAACTTGACCGCGGTATCCAGATCTTTCAGCAGCGTGCGCACGTGCCACTTC
ACCGGCTCGAAACGGCTTTC

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 760; Mature: 760

Protein sequence:

>760_residues
MEWLGLQFVAEQPESGQVILNCTHNPLLVLVAYLVACAASFATLDMAERVAHAEEPGSQRIWRWIGATCLAGGIWAMHFI
SMLAFQAPIGIQYDLPVTLFSLVIALLASWLAMHTLSTPQPSLLQYLKTAIVIGLGIAGMHYVGMAAIESAASAYYDPTL
FLASIVIAIGASFAALWVAGYLREGSGLHIQMLKYVAALILGAGILSMHFTGMAALQLVLPEGQLPTLASQTSHLQLGLT
VALITLLILGSAISAALADKKLQNKEHDLRRVNALLSQLDQARMSLQHVANYDALTNLINRRGFNQIFAEKLSQKTSEGG
MLAVMFLDIDHFKRINDSLGHDAGDELLKVIAQHIKGSVRSHEDVVARFGGDEFCILIGLRDREEARNLAQRIMLKMKEP
IELAGRRMVMTTSIGISLFPEDGSTCDELLKHADLALYQSKGAGRNGVHFFDSNLKNRASLELQLEEELRHALRQENGLL
LYYQPIFELKTGKVTKLEALIRWQHPVHGLLTPDRFIAIAENNGLIAELDNWVLRKACEDLGELSRHGCEELKIAWNCSP
LNLAREELANEIEHALRSAGVAPERLELEVTENALMGNIANTLVLLRQIRALGVSLSIDDFGTGYSSLAYLKRLPLNTLK
VDRSFILDIPKATADMEIVQAIIVMAHTLHLQVVTEGVESLEQYEFLERSGCDFIQGYLLSRPVPLAELRPVLEEINQRK
HAHAVNPLSLARGTFAPVSLDPSAKSLVPHAGASVVRPIR

Sequences:

>Translated_760_residues
MEWLGLQFVAEQPESGQVILNCTHNPLLVLVAYLVACAASFATLDMAERVAHAEEPGSQRIWRWIGATCLAGGIWAMHFI
SMLAFQAPIGIQYDLPVTLFSLVIALLASWLAMHTLSTPQPSLLQYLKTAIVIGLGIAGMHYVGMAAIESAASAYYDPTL
FLASIVIAIGASFAALWVAGYLREGSGLHIQMLKYVAALILGAGILSMHFTGMAALQLVLPEGQLPTLASQTSHLQLGLT
VALITLLILGSAISAALADKKLQNKEHDLRRVNALLSQLDQARMSLQHVANYDALTNLINRRGFNQIFAEKLSQKTSEGG
MLAVMFLDIDHFKRINDSLGHDAGDELLKVIAQHIKGSVRSHEDVVARFGGDEFCILIGLRDREEARNLAQRIMLKMKEP
IELAGRRMVMTTSIGISLFPEDGSTCDELLKHADLALYQSKGAGRNGVHFFDSNLKNRASLELQLEEELRHALRQENGLL
LYYQPIFELKTGKVTKLEALIRWQHPVHGLLTPDRFIAIAENNGLIAELDNWVLRKACEDLGELSRHGCEELKIAWNCSP
LNLAREELANEIEHALRSAGVAPERLELEVTENALMGNIANTLVLLRQIRALGVSLSIDDFGTGYSSLAYLKRLPLNTLK
VDRSFILDIPKATADMEIVQAIIVMAHTLHLQVVTEGVESLEQYEFLERSGCDFIQGYLLSRPVPLAELRPVLEEINQRK
HAHAVNPLSLARGTFAPVSLDPSAKSLVPHAGASVVRPIR
>Mature_760_residues
MEWLGLQFVAEQPESGQVILNCTHNPLLVLVAYLVACAASFATLDMAERVAHAEEPGSQRIWRWIGATCLAGGIWAMHFI
SMLAFQAPIGIQYDLPVTLFSLVIALLASWLAMHTLSTPQPSLLQYLKTAIVIGLGIAGMHYVGMAAIESAASAYYDPTL
FLASIVIAIGASFAALWVAGYLREGSGLHIQMLKYVAALILGAGILSMHFTGMAALQLVLPEGQLPTLASQTSHLQLGLT
VALITLLILGSAISAALADKKLQNKEHDLRRVNALLSQLDQARMSLQHVANYDALTNLINRRGFNQIFAEKLSQKTSEGG
MLAVMFLDIDHFKRINDSLGHDAGDELLKVIAQHIKGSVRSHEDVVARFGGDEFCILIGLRDREEARNLAQRIMLKMKEP
IELAGRRMVMTTSIGISLFPEDGSTCDELLKHADLALYQSKGAGRNGVHFFDSNLKNRASLELQLEEELRHALRQENGLL
LYYQPIFELKTGKVTKLEALIRWQHPVHGLLTPDRFIAIAENNGLIAELDNWVLRKACEDLGELSRHGCEELKIAWNCSP
LNLAREELANEIEHALRSAGVAPERLELEVTENALMGNIANTLVLLRQIRALGVSLSIDDFGTGYSSLAYLKRLPLNTLK
VDRSFILDIPKATADMEIVQAIIVMAHTLHLQVVTEGVESLEQYEFLERSGCDFIQGYLLSRPVPLAELRPVLEEINQRK
HAHAVNPLSLARGTFAPVSLDPSAKSLVPHAGASVVRPIR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=430, Percent_Identity=34.1860465116279, Blast_Score=261, Evalue=1e-70,
Organism=Escherichia coli, GI87081921, Length=436, Percent_Identity=30.2752293577982, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI226510982, Length=404, Percent_Identity=28.7128712871287, Blast_Score=170, Evalue=3e-43,
Organism=Escherichia coli, GI1788502, Length=250, Percent_Identity=34.8, Blast_Score=152, Evalue=7e-38,
Organism=Escherichia coli, GI1790496, Length=259, Percent_Identity=32.8185328185328, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI87081743, Length=231, Percent_Identity=33.3333333333333, Blast_Score=132, Evalue=6e-32,
Organism=Escherichia coli, GI1788849, Length=274, Percent_Identity=31.7518248175182, Blast_Score=132, Evalue=7e-32,
Organism=Escherichia coli, GI87082096, Length=253, Percent_Identity=32.4110671936759, Blast_Score=127, Evalue=3e-30,
Organism=Escherichia coli, GI1786507, Length=224, Percent_Identity=30.8035714285714, Blast_Score=125, Evalue=8e-30,
Organism=Escherichia coli, GI87081980, Length=232, Percent_Identity=31.4655172413793, Blast_Score=124, Evalue=3e-29,
Organism=Escherichia coli, GI1787055, Length=396, Percent_Identity=26.010101010101, Blast_Score=120, Evalue=4e-28,
Organism=Escherichia coli, GI87081845, Length=250, Percent_Identity=30.8, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI1787262, Length=170, Percent_Identity=38.2352941176471, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI145693134, Length=171, Percent_Identity=36.2573099415205, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1788381, Length=201, Percent_Identity=35.3233830845771, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI1786584, Length=170, Percent_Identity=31.1764705882353, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI87081881, Length=171, Percent_Identity=35.672514619883, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87082007, Length=190, Percent_Identity=36.3157894736842, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1787816, Length=172, Percent_Identity=36.046511627907, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1787802, Length=162, Percent_Identity=32.0987654320988, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1788085, Length=167, Percent_Identity=34.1317365269461, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1787410, Length=154, Percent_Identity=29.2207792207792, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI87081977, Length=169, Percent_Identity=28.9940828402367, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1787056, Length=161, Percent_Identity=32.2981366459627, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1788956, Length=184, Percent_Identity=32.6086956521739, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI87081974, Length=149, Percent_Identity=32.8859060402685, Blast_Score=73, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 83538; Mature: 83538

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS50924 MHYT ; PS50883 EAL ; PS50887 GGDEF ; PS00284 SERPIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWLGLQFVAEQPESGQVILNCTHNPLLVLVAYLVACAASFATLDMAERVAHAEEPGSQR
CCCCCCCCEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
IWRWIGATCLAGGIWAMHFISMLAFQAPIGIQYDLPVTLFSLVIALLASWLAMHTLSTPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHCCCCC
PSLLQYLKTAIVIGLGIAGMHYVGMAAIESAASAYYDPTLFLASIVIAIGASFAALWVAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
YLREGSGLHIQMLKYVAALILGAGILSMHFTGMAALQLVLPEGQLPTLASQTSHLQLGLT
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHCCCCHHHHHHH
VALITLLILGSAISAALADKKLQNKEHDLRRVNALLSQLDQARMSLQHVANYDALTNLIN
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRGFNQIFAEKLSQKTSEGGMLAVMFLDIDHFKRINDSLGHDAGDELLKVIAQHIKGSVR
HCCHHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCC
SHEDVVARFGGDEFCILIGLRDREEARNLAQRIMLKMKEPIELAGRRMVMTTSIGISLFP
CHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCHHHCCCEEEEEEECCEEEEC
EDGSTCDELLKHADLALYQSKGAGRNGVHFFDSNLKNRASLELQLEEELRHALRQENGLL
CCCCHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCEEEEEHHHHHHHHHHHCCCEE
LYYQPIFELKTGKVTKLEALIRWQHPVHGLLTPDRFIAIAENNGLIAELDNWVLRKACED
EEECCHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCEEEHHHHHHHHHHHHH
LGELSRHGCEELKIAWNCSPLNLAREELANEIEHALRSAGVAPERLELEVTENALMGNIA
HHHHHHCCHHHEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHH
NTLVLLRQIRALGVSLSIDDFGTGYSSLAYLKRLPLNTLKVDRSFILDIPKATADMEIVQ
HHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHCCCCHHCCCCHHEEECCCCCHHHHHHH
AIIVMAHTLHLQVVTEGVESLEQYEFLERSGCDFIQGYLLSRPVPLAELRPVLEEINQRK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHH
HAHAVNPLSLARGTFAPVSLDPSAKSLVPHAGASVVRPIR
HHCCCCCHHHHCCCCCCCCCCCCHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MEWLGLQFVAEQPESGQVILNCTHNPLLVLVAYLVACAASFATLDMAERVAHAEEPGSQR
CCCCCCCCEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
IWRWIGATCLAGGIWAMHFISMLAFQAPIGIQYDLPVTLFSLVIALLASWLAMHTLSTPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHCCCCC
PSLLQYLKTAIVIGLGIAGMHYVGMAAIESAASAYYDPTLFLASIVIAIGASFAALWVAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
YLREGSGLHIQMLKYVAALILGAGILSMHFTGMAALQLVLPEGQLPTLASQTSHLQLGLT
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHCCCCHHHHHHH
VALITLLILGSAISAALADKKLQNKEHDLRRVNALLSQLDQARMSLQHVANYDALTNLIN
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRGFNQIFAEKLSQKTSEGGMLAVMFLDIDHFKRINDSLGHDAGDELLKVIAQHIKGSVR
HCCHHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCC
SHEDVVARFGGDEFCILIGLRDREEARNLAQRIMLKMKEPIELAGRRMVMTTSIGISLFP
CHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCHHHCCCEEEEEEECCEEEEC
EDGSTCDELLKHADLALYQSKGAGRNGVHFFDSNLKNRASLELQLEEELRHALRQENGLL
CCCCHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCEEEEEHHHHHHHHHHHCCCEE
LYYQPIFELKTGKVTKLEALIRWQHPVHGLLTPDRFIAIAENNGLIAELDNWVLRKACED
EEECCHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCEEEHHHHHHHHHHHHH
LGELSRHGCEELKIAWNCSPLNLAREELANEIEHALRSAGVAPERLELEVTENALMGNIA
HHHHHHCCHHHEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHH
NTLVLLRQIRALGVSLSIDDFGTGYSSLAYLKRLPLNTLKVDRSFILDIPKATADMEIVQ
HHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHCCCCHHCCCCHHEEECCCCCHHHHHHH
AIIVMAHTLHLQVVTEGVESLEQYEFLERSGCDFIQGYLLSRPVPLAELRPVLEEINQRK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHH
HAHAVNPLSLARGTFAPVSLDPSAKSLVPHAGASVVRPIR
HHCCCCCHHHHCCCCCCCCCCCCHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]