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The map label for this gene is yfcG [H]

Identifier: 77457441

GI number: 77457441

Start: 1388227

End: 1388871

Strand: Reverse

Name: yfcG [H]

Synonym: Pfl01_1214

Alternate gene names: 77457441

Gene position: 1388871-1388227 (Counterclockwise)

Preceding gene: 77457443

Following gene: 77457440

Centisome position: 21.57

GC content: 59.84

Gene sequence:

>645_bases
ATGATCGACCTGTATTACTGGACCACGCCCAACGGCCACAAGATTTCCCTGTTCCTCGAAGAAGCGGGCCTGCGTTACGA
CGTGCACCCGATCAATATCAGCCAGGGCGAGCAGTTCCAGCCGCACTTTCTGAAAATCGCCCCGAACAACCGCATCCCGG
CCATCGTCGATCATGAGCCGGCCGATGGCGGCGAACCGTTGTCGCTGTTCGAGTCCGGGGCGATACTGCTGTACCTCGCG
GAAAAGACCGGCAAGTTCCTGCCCAAGGATCTGCGTGGCCGCCAGGTGGCGCTGCAATGGTTGTTCTGGCAAATGGGCGG
GCTGGGGCCGATGGCCGGGCAGAACCATCATTTCAGCCAGTTCGCGCCGGAAAAAATCCCCTACGCGATCAAGCGCTACG
TCGATGAAACCGCCCGCCTGTACGGGGTGCTGGACAAGCAACTGGCCAACAATGAGTTCGTCGCCGGCGGCGAATACAGC
ATCGCCGACATGGCGATCTACCCGTGGATCGTCTCGCACAAATGGCAAAGCCAGAACCTTGAAGACTTCCCGAACGTGCA
GCGCTGGTTCAACCACATCAAGGATCGCCCGGCGACCGTGAAGGCCTACGCGCTGGTGCAGAAGATCAATCCACCGAAGG
CTTGA

Upstream 100 bases:

>100_bases
CACCTCCTGTGACTAAGCAAGCTATCGAACGCACACAGGACAACCTGAAGCCGGCGTTTGCTGTCCGCACGTAAGCCATT
TTCCTGATTTGGAGCTTTCC

Downstream 100 bases:

>100_bases
GTCACCCGGCCTGATCGTTCCCGTGCGCGGGAACGATCAACGGGAAGAAATAACCGCTCGCCCCGCTTGCGCGGCCCCCT
CCTGCTCACTAACGTAGCGG

Product: glutathione S-transferase-like protein

Products: NA

Alternate protein names: GST-like protein yfcG [H]

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MIDLYYWTTPNGHKISLFLEEAGLRYDVHPINISQGEQFQPHFLKIAPNNRIPAIVDHEPADGGEPLSLFESGAILLYLA
EKTGKFLPKDLRGRQVALQWLFWQMGGLGPMAGQNHHFSQFAPEKIPYAIKRYVDETARLYGVLDKQLANNEFVAGGEYS
IADMAIYPWIVSHKWQSQNLEDFPNVQRWFNHIKDRPATVKAYALVQKINPPKA

Sequences:

>Translated_214_residues
MIDLYYWTTPNGHKISLFLEEAGLRYDVHPINISQGEQFQPHFLKIAPNNRIPAIVDHEPADGGEPLSLFESGAILLYLA
EKTGKFLPKDLRGRQVALQWLFWQMGGLGPMAGQNHHFSQFAPEKIPYAIKRYVDETARLYGVLDKQLANNEFVAGGEYS
IADMAIYPWIVSHKWQSQNLEDFPNVQRWFNHIKDRPATVKAYALVQKINPPKA
>Mature_214_residues
MIDLYYWTTPNGHKISLFLEEAGLRYDVHPINISQGEQFQPHFLKIAPNNRIPAIVDHEPADGGEPLSLFESGAILLYLA
EKTGKFLPKDLRGRQVALQWLFWQMGGLGPMAGQNHHFSQFAPEKIPYAIKRYVDETARLYGVLDKQLANNEFVAGGEYS
IADMAIYPWIVSHKWQSQNLEDFPNVQRWFNHIKDRPATVKAYALVQKINPPKA

Specific function: Has disulfide bond reductase activity (in vitro). Has low hydroperoxidase activity with cumene hydroperoxide. Has very low glutathione-S-transferase activity (in vitro) [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1788640, Length=207, Percent_Identity=60.3864734299517, Blast_Score=257, Evalue=5e-70,
Organism=Escherichia coli, GI87082195, Length=224, Percent_Identity=44.1964285714286, Blast_Score=175, Evalue=2e-45,
Organism=Escherichia coli, GI87081789, Length=179, Percent_Identity=30.7262569832402, Blast_Score=64, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6324100, Length=234, Percent_Identity=33.7606837606838, Blast_Score=125, Evalue=6e-30,
Organism=Drosophila melanogaster, GI17933730, Length=196, Percent_Identity=31.1224489795918, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28571670, Length=175, Percent_Identity=30.8571428571429, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI17864592, Length=199, Percent_Identity=32.1608040201005, Blast_Score=90, Evalue=9e-19,
Organism=Drosophila melanogaster, GI17864598, Length=206, Percent_Identity=29.6116504854369, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI17864594, Length=197, Percent_Identity=28.4263959390863, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI17864596, Length=195, Percent_Identity=27.1794871794872, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24646249, Length=198, Percent_Identity=30.3030303030303, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI85725204, Length=202, Percent_Identity=29.7029702970297, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17737923, Length=202, Percent_Identity=29.7029702970297, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24646251, Length=199, Percent_Identity=27.6381909547739, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI20130115, Length=193, Percent_Identity=29.0155440414508, Blast_Score=71, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: NA

Molecular weight: Translated: 24459; Mature: 24459

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDLYYWTTPNGHKISLFLEEAGLRYDVHPINISQGEQFQPHFLKIAPNNRIPAIVDHEP
CEEEEEEECCCCCEEEEEEECCCCEEEEEEEECCCCCCCCCEEEEECCCCCCCEEECCCC
ADGGEPLSLFESGAILLYLAEKTGKFLPKDLRGRQVALQWLFWQMGGLGPMAGQNHHFSQ
CCCCCCHHHHCCCEEEEEEECCCCCCCCCHHCCHHHHHHHHHHHHCCCCCCCCCCCCCHH
FAPEKIPYAIKRYVDETARLYGVLDKQLANNEFVAGGEYSIADMAIYPWIVSHKWQSQNL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHEEEHHHCCCCCCCCCC
EDFPNVQRWFNHIKDRPATVKAYALVQKINPPKA
CCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MIDLYYWTTPNGHKISLFLEEAGLRYDVHPINISQGEQFQPHFLKIAPNNRIPAIVDHEP
CEEEEEEECCCCCEEEEEEECCCCEEEEEEEECCCCCCCCCEEEEECCCCCCCEEECCCC
ADGGEPLSLFESGAILLYLAEKTGKFLPKDLRGRQVALQWLFWQMGGLGPMAGQNHHFSQ
CCCCCCHHHHCCCEEEEEEECCCCCCCCCHHCCHHHHHHHHHHHHCCCCCCCCCCCCCHH
FAPEKIPYAIKRYVDETARLYGVLDKQLANNEFVAGGEYSIADMAIYPWIVSHKWQSQNL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHEEEHHHCCCCCCCCCC
EDFPNVQRWFNHIKDRPATVKAYALVQKINPPKA
CCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]