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The map label for this gene is plsB [H]

Identifier: 77457311

GI number: 77457311

Start: 1253933

End: 1256437

Strand: Reverse

Name: plsB [H]

Synonym: Pfl01_1084

Alternate gene names: 77457311

Gene position: 1256437-1253933 (Counterclockwise)

Preceding gene: 77457313

Following gene: 77457310

Centisome position: 19.51

GC content: 62.12

Gene sequence:

>2505_bases
ATGACCCGTTCCCCGTTCCGCCGTCTTGTGTTTGGCACCTTGCGCCGACTGTTGTATCTCTGGGTTCGCTCCGAGACGAT
CAACCAGTCGTCGTTCACCCTCAACCTAGACCGCAGTCGTCCGGTGTTCTACGTCCTGCAAAACCCATCGCTGACTGATC
TGGCGGTGGTCGACACCGAGTGCACCAAGGCCGGTCTGCCGCGCCCGGTGCTGCCGGTGTCCGTGGGTTCGCTGATCGAA
CCCGCGGCGTTCTTCTACCTGACGCCGGACCCGGACTGGCTCGGCCGCCAGGACAAGCGCGGCGCGCCGCCGACCCTGAC
CCGCCTGGTCAGCGCCCTGAGCCAGAACGCTGCCGAAGATGCACAGATCATTCCGGTCAGCGTGTTCTGGGGCCAGTCGC
CGGACAGCGAGAACAGCCCATGGAAACTGCTGTTCGCCGACAGCTGGGCCGTCACCGGACGCCTGCGCCGGCTGCTGAGC
ATCATGATTCTGGGGCGCAAGACCCGCGTGCAGTTCTCCGCACCGATCCACCTGCGCGAACTGATCGAACACAACAAGGG
CCACGAACGCACCGTGCGCATGGCCCAGCGGATCCTGCGGGTGCACTTCCGCAACCTGAAAGCTGCGGTGATCGGCCCGG
ACATTTCCCACCGCCGCAACCTGGTCAAAGGCCTGCTCAACCAGCCGCTGGTCAAGCAAGCGATCCTCGACGAAGCCGAG
CGCGAAAACATCTCCCCGGAAAAAGCCAAGGCCCAGGCCCTGCGCTATGGCAACGAGATCGCCTCGGACTACACCTACAC
CGCGATCCGTTTTCTGGAAGTCGTACTGAGCTGGTTCTGGAACAAGATCTACGACGGGATCAAGGTCAACCACATCGAAG
GCGTGCAGAAGGTCGCCCAGGGTCACGAAGTGATCTACGTGCCGTGCCACCGCAGCCATATCGACTATCTGCTGCTGTCG
TACCTACTGTTCCGCAACGGCCTGACCCCGCCGCACATCGCCGCCGGAATCAACCTGAACATGCCGGTGATCGGCAGTCT
GCTGCGCCGTGGCGGGGCGTTTTTCATGCGCCGCACGTTCAAGGGCAATCCGCTGTACACCTCGGTGTTCAACGAATACC
TGCACACCCTGTTCACCAAAGGTTTCCCGGTCGAGTACTTCGTCGAAGGCGGGCGCTCGCGTACCGGGCGCATGCTGCAA
CCGAAAACCGGGATGCTGGCGATCACCCTGCGCAGTTTCCTGCGTTCGTCGCGGATGCCGATCGTGTTCGTGCCGGTGTA
CATCGGTTATGAGCGCGTGCTCGAAGGCCGCACCTACCTCGGCGAACTGCGCGGCGCGAGCAAGAAGAAAGAATCGATCT
TCGACATCTTCAAAGTCATCGGCGCGCTCAAGCAGCGCTTCGGCCAGGTGGCGGTGAACTTCGGCGAGCCGATCAAACTG
GCGGAATTCCTCGACAGTGAACAACCAGGCTGGCGCCAGCAGGAACTGGGCCCGCAGTTCAAACCGGCGTGGCTCAACGA
AACTACCAACCGCCTCGGCGAAAAAGTCGCGCAGCACCTGAACGAAGCGGCGGCGATCAACCCGGTCAACCTGGTGGCGC
TGGCGCTGCTGTCGACCACCCGCCTGGCACTGGATGATCGGGCCATGGCGCGGGTGCTGGATCTGTATCTGGCGCTGCTG
CGCAAGGTTCCGTATTCGCCGCACACCACCTTGCCGGAAGGCGATGGCCGCGCGTTGATCGAGCATGTGAAGGACATGGA
TCTGCTGTCCGAGCAGAACGATGCGCTGGGCAAGATTCTGTACCTGGACGAGCAGAACGCCGTCCTGATGACCTATTACC
GCAACAACGTGCTGCACATCTTCGCCCTGCCGGCGCTGCTGGCGAGCTTCTTCCAGAGCACCTCGCGCATGAGCCGCGAA
CAGATCCTGCGCTACACCCGCGCGCTGTATCCGTATCTGCAATCGGAACTGTTCATCCGCTGGACCCTGGACGAACTGGA
TGCAGTCATCGATCAGTGGCTGGAAGCGTTCGTCGAACAAGGCCTGCTGCGTTTCGAGAAAGACGTGTACCTGCGCCCGG
CACCAAGCTCGCGGCATTTCGTGCTGCTGACCCTGCTGTCGAAGAGCATTGCCCAGACCCTGCAACGCTTCTACATGACG
GTTTCACTGCTGCTCAACAGCGGCCAGAACAGCATCAGCGCCGAAGAACTGGAAGACTTGTGCACGGTCATGGCCCAGCG
CCTGTCGATCCTGCATGGCCTGAACGCGCCGGAATTCTTCGACAAGAGCCTGTTCCGCCACTTCATCCAGACCCTGCTCG
ACCTCGACGTGCTGCGTCGCGACGAAGCCGGCAAGTTGAGCTACCACGAACTGCTCGGCGAACTGGCCGAGGGTGCGGCC
AAACGGGTGTTGCCGGCGGAGATTCGCCTGTCGATCCGTCAGGTAGCCCTGCATCGCAGCGAAGATGCGGCCGATCAGGT
CGCCCCCCCTGTGCAAAACGACTAA

Upstream 100 bases:

>100_bases
AGGAGATTACTTCGCCGCTTTTTTGCCGATTTTCGAGTAATCCGGCAAACTGTCGCCCTCCCGAGCAAACGCTCGGTTTA
TCCACTCACGCAGAAGCCGT

Downstream 100 bases:

>100_bases
ATTCCTAAAGGCGCCAGGCTTCTTCTGGCGCCGTCGATACGGAGATCTGCGATGAAAAAACTTTCTCTGCTGGCCGCCGC
CACCCTGCTCAGCGCCTGCC

Product: glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: GPAT [H]

Number of amino acids: Translated: 834; Mature: 833

Protein sequence:

>834_residues
MTRSPFRRLVFGTLRRLLYLWVRSETINQSSFTLNLDRSRPVFYVLQNPSLTDLAVVDTECTKAGLPRPVLPVSVGSLIE
PAAFFYLTPDPDWLGRQDKRGAPPTLTRLVSALSQNAAEDAQIIPVSVFWGQSPDSENSPWKLLFADSWAVTGRLRRLLS
IMILGRKTRVQFSAPIHLRELIEHNKGHERTVRMAQRILRVHFRNLKAAVIGPDISHRRNLVKGLLNQPLVKQAILDEAE
RENISPEKAKAQALRYGNEIASDYTYTAIRFLEVVLSWFWNKIYDGIKVNHIEGVQKVAQGHEVIYVPCHRSHIDYLLLS
YLLFRNGLTPPHIAAGINLNMPVIGSLLRRGGAFFMRRTFKGNPLYTSVFNEYLHTLFTKGFPVEYFVEGGRSRTGRMLQ
PKTGMLAITLRSFLRSSRMPIVFVPVYIGYERVLEGRTYLGELRGASKKKESIFDIFKVIGALKQRFGQVAVNFGEPIKL
AEFLDSEQPGWRQQELGPQFKPAWLNETTNRLGEKVAQHLNEAAAINPVNLVALALLSTTRLALDDRAMARVLDLYLALL
RKVPYSPHTTLPEGDGRALIEHVKDMDLLSEQNDALGKILYLDEQNAVLMTYYRNNVLHIFALPALLASFFQSTSRMSRE
QILRYTRALYPYLQSELFIRWTLDELDAVIDQWLEAFVEQGLLRFEKDVYLRPAPSSRHFVLLTLLSKSIAQTLQRFYMT
VSLLLNSGQNSISAEELEDLCTVMAQRLSILHGLNAPEFFDKSLFRHFIQTLLDLDVLRRDEAGKLSYHELLGELAEGAA
KRVLPAEIRLSIRQVALHRSEDAADQVAPPVQND

Sequences:

>Translated_834_residues
MTRSPFRRLVFGTLRRLLYLWVRSETINQSSFTLNLDRSRPVFYVLQNPSLTDLAVVDTECTKAGLPRPVLPVSVGSLIE
PAAFFYLTPDPDWLGRQDKRGAPPTLTRLVSALSQNAAEDAQIIPVSVFWGQSPDSENSPWKLLFADSWAVTGRLRRLLS
IMILGRKTRVQFSAPIHLRELIEHNKGHERTVRMAQRILRVHFRNLKAAVIGPDISHRRNLVKGLLNQPLVKQAILDEAE
RENISPEKAKAQALRYGNEIASDYTYTAIRFLEVVLSWFWNKIYDGIKVNHIEGVQKVAQGHEVIYVPCHRSHIDYLLLS
YLLFRNGLTPPHIAAGINLNMPVIGSLLRRGGAFFMRRTFKGNPLYTSVFNEYLHTLFTKGFPVEYFVEGGRSRTGRMLQ
PKTGMLAITLRSFLRSSRMPIVFVPVYIGYERVLEGRTYLGELRGASKKKESIFDIFKVIGALKQRFGQVAVNFGEPIKL
AEFLDSEQPGWRQQELGPQFKPAWLNETTNRLGEKVAQHLNEAAAINPVNLVALALLSTTRLALDDRAMARVLDLYLALL
RKVPYSPHTTLPEGDGRALIEHVKDMDLLSEQNDALGKILYLDEQNAVLMTYYRNNVLHIFALPALLASFFQSTSRMSRE
QILRYTRALYPYLQSELFIRWTLDELDAVIDQWLEAFVEQGLLRFEKDVYLRPAPSSRHFVLLTLLSKSIAQTLQRFYMT
VSLLLNSGQNSISAEELEDLCTVMAQRLSILHGLNAPEFFDKSLFRHFIQTLLDLDVLRRDEAGKLSYHELLGELAEGAA
KRVLPAEIRLSIRQVALHRSEDAADQVAPPVQND
>Mature_833_residues
TRSPFRRLVFGTLRRLLYLWVRSETINQSSFTLNLDRSRPVFYVLQNPSLTDLAVVDTECTKAGLPRPVLPVSVGSLIEP
AAFFYLTPDPDWLGRQDKRGAPPTLTRLVSALSQNAAEDAQIIPVSVFWGQSPDSENSPWKLLFADSWAVTGRLRRLLSI
MILGRKTRVQFSAPIHLRELIEHNKGHERTVRMAQRILRVHFRNLKAAVIGPDISHRRNLVKGLLNQPLVKQAILDEAER
ENISPEKAKAQALRYGNEIASDYTYTAIRFLEVVLSWFWNKIYDGIKVNHIEGVQKVAQGHEVIYVPCHRSHIDYLLLSY
LLFRNGLTPPHIAAGINLNMPVIGSLLRRGGAFFMRRTFKGNPLYTSVFNEYLHTLFTKGFPVEYFVEGGRSRTGRMLQP
KTGMLAITLRSFLRSSRMPIVFVPVYIGYERVLEGRTYLGELRGASKKKESIFDIFKVIGALKQRFGQVAVNFGEPIKLA
EFLDSEQPGWRQQELGPQFKPAWLNETTNRLGEKVAQHLNEAAAINPVNLVALALLSTTRLALDDRAMARVLDLYLALLR
KVPYSPHTTLPEGDGRALIEHVKDMDLLSEQNDALGKILYLDEQNAVLMTYYRNNVLHIFALPALLASFFQSTSRMSREQ
ILRYTRALYPYLQSELFIRWTLDELDAVIDQWLEAFVEQGLLRFEKDVYLRPAPSSRHFVLLTLLSKSIAQTLQRFYMTV
SLLLNSGQNSISAEELEDLCTVMAQRLSILHGLNAPEFFDKSLFRHFIQTLLDLDVLRRDEAGKLSYHELLGELAEGAAK
RVLPAEIRLSIRQVALHRSEDAADQVAPPVQND

Specific function: De novo phospholipid biosynthesis; first step. [C]

COG id: COG2937

COG function: function code I; Glycerol-3-phosphate O-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPAT/DAPAT family [H]

Homologues:

Organism=Homo sapiens, GI7657134, Length=415, Percent_Identity=32.5301204819277, Blast_Score=196, Evalue=6e-50,
Organism=Homo sapiens, GI190358539, Length=585, Percent_Identity=24.957264957265, Blast_Score=158, Evalue=2e-38,
Organism=Escherichia coli, GI87082362, Length=831, Percent_Identity=38.8688327316486, Blast_Score=552, Evalue=1e-158,
Organism=Caenorhabditis elegans, GI25147672, Length=340, Percent_Identity=34.1176470588235, Blast_Score=173, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI71988723, Length=506, Percent_Identity=26.4822134387352, Blast_Score=148, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI71988728, Length=408, Percent_Identity=27.6960784313726, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI17864692, Length=313, Percent_Identity=34.185303514377, Blast_Score=172, Evalue=9e-43,
Organism=Drosophila melanogaster, GI21357731, Length=542, Percent_Identity=26.7527675276753, Blast_Score=152, Evalue=8e-37,
Organism=Drosophila melanogaster, GI24650752, Length=542, Percent_Identity=26.7527675276753, Blast_Score=152, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24650754, Length=542, Percent_Identity=26.7527675276753, Blast_Score=152, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR022284 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.15 [H]

Molecular weight: Translated: 94909; Mature: 94778

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRSPFRRLVFGTLRRLLYLWVRSETINQSSFTLNLDRSRPVFYVLQNPSLTDLAVVDTE
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEECCCCCCEEEEEECH
CTKAGLPRPVLPVSVGSLIEPAAFFYLTPDPDWLGRQDKRGAPPTLTRLVSALSQNAAED
HHHCCCCCCCCCCCHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCC
AQIIPVSVFWGQSPDSENSPWKLLFADSWAVTGRLRRLLSIMILGRKTRVQFSAPIHLRE
CEEEEEEEEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHH
LIEHNKGHERTVRMAQRILRVHFRNLKAAVIGPDISHRRNLVKGLLNQPLVKQAILDEAE
HHHCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHH
RENISPEKAKAQALRYGNEIASDYTYTAIRFLEVVLSWFWNKIYDGIKVNHIEGVQKVAQ
HCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHC
GHEVIYVPCHRSHIDYLLLSYLLFRNGLTPPHIAAGINLNMPVIGSLLRRGGAFFMRRTF
CCCEEEECCCCCHHHHHHHHHHHHHCCCCCCHHCCCCCCCHHHHHHHHHCCCHHHHHHHC
KGNPLYTSVFNEYLHTLFTKGFPVEYFVEGGRSRTGRMLQPKTGMLAITLRSFLRSSRMP
CCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
IVFVPVYIGYERVLEGRTYLGELRGASKKKESIFDIFKVIGALKQRFGQVAVNFGEPIKL
EEEEEHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHH
AEFLDSEQPGWRQQELGPQFKPAWLNETTNRLGEKVAQHLNEAAAINPVNLVALALLSTT
HHHHCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
RLALDDRAMARVLDLYLALLRKVPYSPHTTLPEGDGRALIEHVKDMDLLSEQNDALGKIL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEE
YLDEQNAVLMTYYRNNVLHIFALPALLASFFQSTSRMSREQILRYTRALYPYLQSELFIR
EEECCCCEEEEEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
WTLDELDAVIDQWLEAFVEQGLLRFEKDVYLRPAPSSRHFVLLTLLSKSIAQTLQRFYMT
EEHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VSLLLNSGQNSISAEELEDLCTVMAQRLSILHGLNAPEFFDKSLFRHFIQTLLDLDVLRR
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
DEAGKLSYHELLGELAEGAAKRVLPAEIRLSIRQVALHRSEDAADQVAPPVQND
CCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHCCCCCCCC
>Mature Secondary Structure 
TRSPFRRLVFGTLRRLLYLWVRSETINQSSFTLNLDRSRPVFYVLQNPSLTDLAVVDTE
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEECCCCCCEEEEEECH
CTKAGLPRPVLPVSVGSLIEPAAFFYLTPDPDWLGRQDKRGAPPTLTRLVSALSQNAAED
HHHCCCCCCCCCCCHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCC
AQIIPVSVFWGQSPDSENSPWKLLFADSWAVTGRLRRLLSIMILGRKTRVQFSAPIHLRE
CEEEEEEEEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHH
LIEHNKGHERTVRMAQRILRVHFRNLKAAVIGPDISHRRNLVKGLLNQPLVKQAILDEAE
HHHCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHH
RENISPEKAKAQALRYGNEIASDYTYTAIRFLEVVLSWFWNKIYDGIKVNHIEGVQKVAQ
HCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHC
GHEVIYVPCHRSHIDYLLLSYLLFRNGLTPPHIAAGINLNMPVIGSLLRRGGAFFMRRTF
CCCEEEECCCCCHHHHHHHHHHHHHCCCCCCHHCCCCCCCHHHHHHHHHCCCHHHHHHHC
KGNPLYTSVFNEYLHTLFTKGFPVEYFVEGGRSRTGRMLQPKTGMLAITLRSFLRSSRMP
CCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
IVFVPVYIGYERVLEGRTYLGELRGASKKKESIFDIFKVIGALKQRFGQVAVNFGEPIKL
EEEEEHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHH
AEFLDSEQPGWRQQELGPQFKPAWLNETTNRLGEKVAQHLNEAAAINPVNLVALALLSTT
HHHHCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
RLALDDRAMARVLDLYLALLRKVPYSPHTTLPEGDGRALIEHVKDMDLLSEQNDALGKIL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEE
YLDEQNAVLMTYYRNNVLHIFALPALLASFFQSTSRMSREQILRYTRALYPYLQSELFIR
EEECCCCEEEEEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
WTLDELDAVIDQWLEAFVEQGLLRFEKDVYLRPAPSSRHFVLLTLLSKSIAQTLQRFYMT
EEHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VSLLLNSGQNSISAEELEDLCTVMAQRLSILHGLNAPEFFDKSLFRHFIQTLLDLDVLRR
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
DEAGKLSYHELLGELAEGAAKRVLPAEIRLSIRQVALHRSEDAADQVAPPVQND
CCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA